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Regulation Of Germline Transcription In The Immunoglobulin Heavy Chain Locus
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Book Synopsis Regulation of Germline Transcription in the Immunoglobulin Heavy Chain Locus by : Jurga Laurencikiene
Download or read book Regulation of Germline Transcription in the Immunoglobulin Heavy Chain Locus written by Jurga Laurencikiene and published by . This book was released on 2004 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunoglobulin Genes by : Tasuku Honjo
Download or read book Immunoglobulin Genes written by Tasuku Honjo and published by Academic Press. This book was released on 2012-12-02 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunoglobin Genes is the first comprehensive book on the structure, function, and expression of the genes encoding antibodies in normal and neoplastic cells.
Book Synopsis Role of Immunoglobulin [subscript Mu] Heavy Chain in the Regulation of [subscript Kappa] Light Chain Gene Rearrangement by : Alan Murray Shapiro
Download or read book Role of Immunoglobulin [subscript Mu] Heavy Chain in the Regulation of [subscript Kappa] Light Chain Gene Rearrangement written by Alan Murray Shapiro and published by . This book was released on 1993 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis V(D)J Recombination by : Pierre Ferrier
Download or read book V(D)J Recombination written by Pierre Ferrier and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: v(D)J recombination: for the community of immunologists and developmental biologists, the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. Yet, for many-from experienced scientists to trainees-it represents a (rather too) sophisticated process whose true insight is excessively demanding. However, when not simplyconsidered as a private ground for a few aficionados, it can be seen as a way of understanding how maturelympho cytes carry on their basic functions. For the group of aficionados-which includes this editor-it is an elegant paradigm featuring many fascinating evolutionary achievements of which the biological world alone has the secret. These include a subtle biochemical principle most likelyhijacked some 470 million years ago from an ancestral gene invader and since then cleverly adapted by jawed vertebrates to precisely cleave and rearrange their antigen receptor (Ig andTCR)loci. This invader would itself have assigned the services of the nonhomologous end joining (NHEJ) DNArepair machinery as well as various DNApolymerases or transferases to work in concert with developmental clues in lymphoid cell lineages to generate an immune repertoire and efficient host surveillance while avoiding autoimmunity. Recently, important new refinements in these systems have emerged, continuing to challenge ourknowledge andbeliefs. These arejust thetopics covered by the senior authors-all established leaders in this field-and their colleagues, whilst writing the various chapters in V(D)J Recombination.
Book Synopsis Janeway's Immunobiology by : Kenneth Murphy
Download or read book Janeway's Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Book Synopsis Regulatory Elements Necessary for Termination of Transcription with the Immunoglobulin Heavy Chain Gene Locus by : Bethany Sue Beilue Moore
Download or read book Regulatory Elements Necessary for Termination of Transcription with the Immunoglobulin Heavy Chain Gene Locus written by Bethany Sue Beilue Moore and published by . This book was released on 1992 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci by :
Download or read book Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci written by and published by Academic Press. This book was released on 2015-11-16 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes. Focuses on the generation of an effective immune response to invading pathogens Contains contributions from leading authorities Informs and updates on all the latest developments in the field of immunology
Book Synopsis The Generation of Diversity by : Alfred I. Tauber
Download or read book The Generation of Diversity written by Alfred I. Tauber and published by Harvard University Press. This book was released on 2000 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an intellectual history of the major theoretical problem in immunology and its resolution in the post-World War II period. In recent years immunology has been one of the most exciting--and successful--fields of biomedical research; this book provides essential background for understanding the conceptual conflicts occurring in the field.
Book Synopsis Transcription Factors Regulating the Immunoglobulin Heavy Chain Locus by : Tove Andersson
Download or read book Transcription Factors Regulating the Immunoglobulin Heavy Chain Locus written by Tove Andersson and published by . This book was released on 1999 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Molecular Biology of B Cells by : Tasuku Honjo
Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Academic Press. This book was released on 2014-12-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
Book Synopsis Epigenetic Regulation of Lymphocyte Development by : Cornelis Murre
Download or read book Epigenetic Regulation of Lymphocyte Development written by Cornelis Murre and published by Springer Science & Business Media. This book was released on 2012-01-13 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.
Book Synopsis The Roles of E2A and EBF in the Regulation of the Recombination of the Immunoglobulin Loci by : William Joseph Jr Romanow
Download or read book The Roles of E2A and EBF in the Regulation of the Recombination of the Immunoglobulin Loci written by William Joseph Jr Romanow and published by . This book was released on 2000 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Transgene Analysis of Switch Recombination and Murine Γ1 Germline Transcription by : Kirk Alan Cunningham
Download or read book Transgene Analysis of Switch Recombination and Murine Γ1 Germline Transcription written by Kirk Alan Cunningham and published by . This book was released on 1997 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Immunoglobulin FactsBook by : Marie-Paule Lefranc
Download or read book The Immunoglobulin FactsBook written by Marie-Paule Lefranc and published by Academic Press. This book was released on 2001-05-23 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The FactsBook series has established itself as the best source of easily accessible and accurate facts about protein groups. Books in the series use an easy-to-follow format and are meticulously researched and compiled by experts in the field.The Immunoglobulin FactsBook is the first published reference for all 203 human functional and ORF immunoglobulin genes. It is complete and standardized and employs nomenclature approved by the HUGO Nomenclature Committee.
Book Synopsis Germline Transcription of the Murine Immunoglobulin Γ1 Locus by : Laura Ann Elenich
Download or read book Germline Transcription of the Murine Immunoglobulin Γ1 Locus written by Laura Ann Elenich and published by . This book was released on 1994 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Comparative Immunoglobulin Genetics by : Azad K. Kaushik
Download or read book Comparative Immunoglobulin Genetics written by Azad K. Kaushik and published by CRC Press. This book was released on 2014-05-01 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contemporary book covers significant new knowledge that has emerged during the last two decades and, thus, provides novel antibody phylogenetic perspectives relevant to development of new antibody-based therapeutics and vaccines. It fills a much-needed niche in the area of immunoglobulin genetics across species from a comparative perspective.
Book Synopsis Regulation of Recombination at the Immunoglobulin Heavy Chain Locus by : Jamie Kathleen Geier
Download or read book Regulation of Recombination at the Immunoglobulin Heavy Chain Locus written by Jamie Kathleen Geier and published by . This book was released on 2006 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Heavy Chain locus undergoes a series of two rearrangements in B cells; the first joins a DH and JH gene segment; and the second joins a VH gene segment to the rearranged DJH segments. The three segments together code for a complete Heavy Chain protein that is expressed exclusively in B cells. Once a Heavy Chain is expressed, V-to-DJ rearrangement is blocked, in a process referred to as allelic exclusion. Our research sought to identify mechanisms involved in maintaining the cell-type and stage specificity of VH to DJH recombination as well as in maintaining allelic exclusion.
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