Regulation Of Caveolae Medicated Endocytosis And Endothelial Cell Permeability By Intersectin 2l

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Lung Endothelium

Author : Mary I. Townsley
Publisher : Biota Publishing
ISBN 13 : 1615044493
Total Pages : 68 pages
Book Rating : 4.6/5 (15 download)

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Book Synopsis Lung Endothelium by : Mary I. Townsley

Download or read book Lung Endothelium written by Mary I. Townsley and published by Biota Publishing. This book was released on 2015-09-01 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pulmonary endothelium forms the inner lining of blood vessels, where it interprets the complex mechanical and chemical environment within the circulation and adjusts its behavior to facilitate vascular homeostasis. Although endothelium fulfills many essential functions, including regulation of vascular pressure, circulating cell transmigration, coagulation, and hormone metabolism and/or delivery, a principal role is to form a semi-permeable barrier that limits fluid, solute and macromolecular access to the interstitial space. Physiological properties that govern such permeability characteristics are defined by the Starling equation, which assumes that endothelial cells throughout the circulation are all alike. However, in recent years it has become evident that endothelial cells in pulmonary arteries, capillary and veins are heterogeneous in structure and function. Here, we review evidence for endothelial heterogeneity among these pulmonary vascular segments, and consider the implications for such heterogeneity in lung fluid balance, especially as it relates to the Starling equation.

Trafficking Inside Cells

Author : Nava Segev
Publisher : Springer Science & Business Media
ISBN 13 : 038793877X
Total Pages : 459 pages
Book Rating : 4.3/5 (879 download)

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Book Synopsis Trafficking Inside Cells by : Nava Segev

Download or read book Trafficking Inside Cells written by Nava Segev and published by Springer Science & Business Media. This book was released on 2010-05-30 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

Biology and Regulation of Blood‐Tissue Barriers

Author : C. Yan Cheng
Publisher : Springer Science & Business Media
ISBN 13 : 1461447119
Total Pages : 380 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Biology and Regulation of Blood‐Tissue Barriers by : C. Yan Cheng

Download or read book Biology and Regulation of Blood‐Tissue Barriers written by C. Yan Cheng and published by Springer Science & Business Media. This book was released on 2014-01-25 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was written by many outstanding investigators who have spent decades to study different aspects of blood‐tissue barrier function. They have summarized some of the latest and fascinating development in their fields of research including the blood‐brain barrier, the blood‐retinal barrier, the gut barrier, the blood‐biliary barrier, the blood‐follicle barrier, the blood‐epididymis barrier, the blood‐testis barrier, the tight junction barrier in general as well as barriers in the female reproductive tract. Included are also chapters that focus on topics that are physiologically applicable to all blood‐tissue barriers. Many of these chapters also include information on specific human diseases, such as pathological changes of the gut barrier that cause bowel disorders resulting from inflammation of the epithelial lining in the intestine, and infertility in men as a result of disruption of the blood‐epididymal and/or blood‐testis barriers; and on new therapeutic approaches (e.g., drug delivery across the blood‐brain and the blood‐retinal barriers).

Drug Transport Across the Blood-brain Barrier

Author : A.G. de Boer
Publisher : CRC Press
ISBN 13 : 9789057020322
Total Pages : 240 pages
Book Rating : 4.0/5 (23 download)

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Book Synopsis Drug Transport Across the Blood-brain Barrier by : A.G. de Boer

Download or read book Drug Transport Across the Blood-brain Barrier written by A.G. de Boer and published by CRC Press. This book was released on 1997-04-08 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: The availability of various in vitro and in vivo techniques has considerably advanced the research on drug transport and metabolism across the blood-brain barrier (BBB). These specialized and sophisticated experimental strategies are of fundamental importance if one is to gain a greater understanding of enhanced and selective drug delivery to the brain. The reader will find in this book methods for in vitro endothelial/astrocyte cell culture models, and for in vivo intracerebral microdialysis to study drug tranport across the BBB. This book, however, is not merely a laboratory manual consisting of recipes for BBB research; it permits the presentation of the different methods in fine detail, revealing tricks and short cuts that frequently do not appear in the literature. The researcher is well aware that differences (subtle or otherwise) in experimental steps used in different laboratories may influence the outcome of any particular procedure. The book also illustrates the accessibility and the application of the different methods in different species. Background information of the protocol is given in every chapter, which also contains a literature list that the reader may wish to refer to for further information. This volume will be invaluable to basic researchers as well as to those involved in the search for agents suitable for pharmaceutic intervention in the central nervous system.

The Biophysics of Cell Membranes

Author : Richard M. Epand
Publisher : Springer
ISBN 13 : 9811062447
Total Pages : 224 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis The Biophysics of Cell Membranes by : Richard M. Epand

Download or read book The Biophysics of Cell Membranes written by Richard M. Epand and published by Springer. This book was released on 2017-09-25 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.

Brain Peptides

Author : Dorothy T. Krieger
Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 1054 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Brain Peptides by : Dorothy T. Krieger

Download or read book Brain Peptides written by Dorothy T. Krieger and published by Wiley-Interscience. This book was released on 1983-11-14 with total page 1054 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first major comprehensive overview of the anatomical, physiological, evolutionary, and embryological aspects of brain peptides, focusing on peptides described in the past decade. Examines the role of peptides in affecting major homeostatic systems. Presents the methodologies applicable to the study of brain peptides. Summarizes current knowledge of individual peptides.

Nanocarrier Technologies

Author : M. Reza Mozafari
Publisher : Springer Science & Business Media
ISBN 13 : 1402050410
Total Pages : 238 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Nanocarrier Technologies by : M. Reza Mozafari

Download or read book Nanocarrier Technologies written by M. Reza Mozafari and published by Springer Science & Business Media. This book was released on 2006-09-24 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as an advanced survey of the field, this book describes the key research parameters of nanocarrier technologies. It is the first book with this topic. It comprises a collection of scientific articles from top research people in the field and provides an up-to-date source containing recent citation and bibliography. The book is an indispensable source of information for new researchers and scientists.

Cell Physiology Source Book

Author : Nicholas Sperelakis
Publisher : Elsevier
ISBN 13 : 0080574556
Total Pages : 1262 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Cell Physiology Source Book by : Nicholas Sperelakis

Download or read book Cell Physiology Source Book written by Nicholas Sperelakis and published by Elsevier. This book was released on 2012-12-02 with total page 1262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This authoritative book gathers together a broad range of ideas and topics that define the field. It provides clear, concise, and comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics. The Third Edition contains substantial new material. Most chapters have been thoroughly reworked. The book includes chapters on important topics such as sensory transduction, the physiology of protozoa and bacteria, the regulation of cell division, and programmed cell death. - Completely revised and updated - includes 8 new chapters on such topics as membrane structure, intracellular chloride regulation, transport, sensory receptors, pressure, and olfactory/taste receptors - Includes broad coverage of both animal and plant cells - Appendixes review basics of the propagation of action potentials, electricity, and cable properties - Authored by leading experts in the field - Clear, concise, comprehensive coverage of all aspects of cellular physiology from fundamental concepts to more advanced topics

Regenerative Pharmacology

Author : George J. Christ
Publisher : Cambridge University Press
ISBN 13 : 0521899494
Total Pages : 361 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Regenerative Pharmacology by : George J. Christ

Download or read book Regenerative Pharmacology written by George J. Christ and published by Cambridge University Press. This book was released on 2013-04-15 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: A state-of-the-art primer on the role of pharmacological sciences in regenerative medicine, for advanced students, postdoctoral fellows, and researchers.

Clinical Aspects of Electroporation

Author : Stephen T. Kee
Publisher : Springer Science & Business Media
ISBN 13 : 1441983635
Total Pages : 251 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Clinical Aspects of Electroporation by : Stephen T. Kee

Download or read book Clinical Aspects of Electroporation written by Stephen T. Kee and published by Springer Science & Business Media. This book was released on 2011-04-06 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electroporation is the forefront in tumor ablation. This book presents the basic principles and clinical applications of electroporation, including the latest research results and patient data. A comprehensive approach to the basic science behind the development of this ground-breaking technique and its introduction into clinical practice, the book discusses the entire spectrum of currently available reversible treatments, the emerging irreversible applications, and their impact on patient care. Clinical Aspects of Electroporation is the first book intended for clinicians on this extremely important and rapidly developing field.

The Glutamate Receptors

Author : Robert W. Gereau
Publisher : Springer Science & Business Media
ISBN 13 : 1597450553
Total Pages : 585 pages
Book Rating : 4.5/5 (974 download)

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Book Synopsis The Glutamate Receptors by : Robert W. Gereau

Download or read book The Glutamate Receptors written by Robert W. Gereau and published by Springer Science & Business Media. This book was released on 2008-02-23 with total page 585 pages. Available in PDF, EPUB and Kindle. Book excerpt: This insightful and comprehensive book covers nearly every aspect of glutamate receptor structure and function for the working researcher and student. It condenses two previous landmark volumes into one easily accessible volume, and covers the extraordinary research and significant developments in the decade since the previous books were published. This includes the central role glutamate receptors play in neurotransmission.

An Introduction to Biotechnology

Author : W.T. Godbey
Publisher : Elsevier
ISBN 13 : 1908818484
Total Pages : 435 pages
Book Rating : 4.9/5 (88 download)

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Book Synopsis An Introduction to Biotechnology by : W.T. Godbey

Download or read book An Introduction to Biotechnology written by W.T. Godbey and published by Elsevier. This book was released on 2014-12-08 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: An Introduction to Biotechnology is a biotechnology textbook aimed at undergraduates. It covers the basics of cell biology, biochemistry and molecular biology, and introduces laboratory techniques specific to the technologies addressed in the book; it addresses specific biotechnologies at both the theoretical and application levels.Biotechnology is a field that encompasses both basic science and engineering. There are currently few, if any, biotechnology textbooks that adequately address both areas. Engineering books are equation-heavy and are written in a manner that is very difficult for the non-engineer to understand. Numerous other attempts to present biotechnology are written in a flowery manner with little substance. The author holds one of the first PhDs granted in both biosciences and bioengineering. He is more than an author enamoured with the wow-factor associated with biotechnology; he is a practicing researcher in gene therapy, cell/tissue engineering, and other areas and has been involved with emerging technologies for over a decade. Having made the assertion that there is no acceptable text for teaching a course to introduce biotechnology to both scientists and engineers, the author committed himself to resolving the issue by writing his own. - The book is of interest to a wide audience because it includes the necessary background for understanding how a technology works. - Engineering principles are addressed, but in such a way that an instructor can skip the sections without hurting course content - The author has been involved with many biotechnologies through his own direct research experiences. The text is more than a compendium of information - it is an integrated work written by an author who has experienced first-hand the nuances associated with many of the major biotechnologies of general interest today.

Fundamental Neuroscience

Author : Larry Squire
Publisher : Academic Press
ISBN 13 : 0080561020
Total Pages : 1277 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Fundamental Neuroscience by : Larry Squire

Download or read book Fundamental Neuroscience written by Larry Squire and published by Academic Press. This book was released on 2008-04-02 with total page 1277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamental Neuroscience, Third Edition introduces graduate and upper-level undergraduate students to the full range of contemporary neuroscience. Addressing instructor and student feedback on the previous edition, all of the chapters are rewritten to make this book more concise and student-friendly than ever before. Each chapter is once again heavily illustrated and provides clinical boxes describing experiments, disorders, and methodological approaches and concepts.Capturing the promise and excitement of this fast-moving field, Fundamental Neuroscience, 3rd Edition is the text that students will be able to reference throughout their neuroscience careers! 30% new material including new chapters on Dendritic Development and Spine Morphogenesis, Chemical Senses, Cerebellum, Eye Movements, Circadian Timing, Sleep and Dreaming, and Consciousness Additional text boxes describing key experiments, disorders, methods, and concepts Multiple model system coverage beyond rats, mice, and monkeys Extensively expanded index for easier referencing

Elements of Molecular Neurobiology

Author : C. U. M. Smith
Publisher : John Wiley & Sons
ISBN 13 : 047085717X
Total Pages : 630 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Elements of Molecular Neurobiology by : C. U. M. Smith

Download or read book Elements of Molecular Neurobiology written by C. U. M. Smith and published by John Wiley & Sons. This book was released on 2003-06-13 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edition of the popular text incorporates recent advances in neurobiology enabled by modern molecular biology techniques. Understanding how the brain works from a molecular level allows research to better understand behaviours, cognition, and neuropathologies. Since the appearance six years ago of the second edition, much more has been learned about the molecular biology of development and its relations with early evolution. This "evodevo" (as it has come to be known) framework also has a great deal of bearing on our understanding of neuropathologies as dysfunction of early onset genes can cause neurodegeneration in later life. Advances in our understanding of the genomes and proteomes of a number of organisms also greatly influence our understanding of neurobiology. * Well known and widely used as a text throughout the UK, good reviews from students and lecturers. * Good complement to Fundementals of Psychopharmacology by Brian Leonard. This book will be of particular interest to biomedical undergraduates undertaking a neuroscience unit, neuroscience postgraduates, physiologists, pharmacologists. It is also a useful basic reference for university libraries. Maurice Elphick, Queen Mary, University of London "I do like this book and it is the recommended textbook for my course in Molecular Neuroscience. The major strength of the book is the overall simplicity of the format both in terms of layout and diagrams."

Polymer Science and Nanotechnology

Author : Ravin Narain
Publisher : Elsevier
ISBN 13 : 0128168072
Total Pages : 488 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polymer Science and Nanotechnology by : Ravin Narain

Download or read book Polymer Science and Nanotechnology written by Ravin Narain and published by Elsevier. This book was released on 2020-06-16 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymer Science and Nanotechnology: Fundamentals and Applications brings together the latest advances in polymer science and nanoscience. Sections explain the fundamentals of polymer science, including key aspects and methods in terms of molecular structure, synthesis, characterization, microstructure, phase structure and processing and properties before discussing the materials of particular interest and utility for novel applications, such as hydrogels, natural polymers, smart polymers and polymeric biomaterials. The second part of the book examines essential techniques in nanotechnology, with an emphasis on the utilization of advanced polymeric materials in the context of nanoscience. Throughout the book, chapters are prepared so that materials and products can be geared towards specific applications. Two chapters cover, in detail, major application areas, including fuel and solar cells, tissue engineering, drug and gene delivery, membranes, water treatment and oil recovery. - Presents the latest applications of polymers and polymeric nanomaterials, across energy, biomedical, pharmaceutical, and environmental fields - Contains detailed coverage of polymer nanocomposites, polymer nanoparticles, and hybrid polymer-metallic nanoparticles - Supports an interdisciplinary approach, enabling readers from different disciplines to understand polymer science and nanotechnology and the interface between them

Transport Organs

Author : G. Giebisch
Publisher : Springer
ISBN 13 : 9783540088950
Total Pages : 508 pages
Book Rating : 4.0/5 (889 download)

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Book Synopsis Transport Organs by : G. Giebisch

Download or read book Transport Organs written by G. Giebisch and published by Springer. This book was released on 1979 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Physics of Cancer

Author : Claudia Mierke
Publisher : Iph001
ISBN 13 : 9780750317511
Total Pages : 500 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis Physics of Cancer by : Claudia Mierke

Download or read book Physics of Cancer written by Claudia Mierke and published by Iph001. This book was released on 2018-10-24 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.