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Transport Organs
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Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman
Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Book Synopsis Organ Procurement and Transplantation by : Institute of Medicine
Download or read book Organ Procurement and Transplantation written by Institute of Medicine and published by National Academies Press. This book was released on 1999-12-09 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each day, nearly 60 Americans receive a transplanted kidney, liver, or other organâ€"a literal "second chance at life"â€"but 11 others die waiting for an organ transplant. The number of donors, although rising, is not growing fast enough to meet the increasing demand. Intended to improve the current system of organ procurement and allocation, the "Final Rule," a 1998 regulation issued by the U.S. Department of Health and Human Services, sparked further controversy with its attempts to eliminate the apparent geographic disparities in the time an individual must wait for an organ. This book assesses the potential impact of the Final Rule on organ transplantation. It also presents new, original analyses of data, and assesses medical practices, social and economic observations, and other information on: access to transplantation services for low-income populations and racial and ethnic minority groups; organ donation rates; waiting times for transplantation; patient survival rates and organ failure rates leading to retransplantation; and cost of organ transplantation services.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309464870 Total Pages :171 pages Book Rating :4.3/5 (94 download)
Book Synopsis Opportunities for Organ Donor Intervention Research by : National Academies of Sciences, Engineering, and Medicine
Download or read book Opportunities for Organ Donor Intervention Research written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-01-21 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: The organ donation and transplantation system strives to honor the gift of donated organs by fully using those organs to save and improve the quality of the lives of their recipients. However, there are not enough donated organs to meet the demand and some donated organs may not be recovered, some recovered organs may not be transplanted, and some transplanted organs may not function adequately. Organ donor intervention research can test and assess interventions (e.g., medications, devices, and donor management protocols) to maintain or improve organ quality prior to, during, and following transplantation. The intervention is administered either while the organ is still in the deceased donor or after it is recovered from the donor but before it is transplanted into a recipient. Organ donor intervention research presents new challenges to the organ donation and transplantation community because of ethical questions about who should be considered a human subject in a research study, whose permission and oversight are needed, and how to ensure that such research does not threaten the equitable distribution of a scarce and valuable resource. Opportunities for Organ Donor Intervention Research focuses on the ethical, legal, regulatory, policy, and organizational issues relevant to the conduct of research in the United States involving deceased organ donors. This report provides recommendations for how to conduct organ donor intervention research in a manner that maintains high ethical standards, that ensures dignity and respect for deceased organ donors and their families, that provides transparency and information for transplant candidates who might receive a research organ, and that supports and sustains the public's trust in the process of organ donation and transplantation.
Book Synopsis Surgical Technique of the Abdominal Organ Procurement by : Andrzej Baranski
Download or read book Surgical Technique of the Abdominal Organ Procurement written by Andrzej Baranski and published by Springer Science & Business Media. This book was released on 2009-03-01 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book encompasses Dr Baranski’s 20 year experience in the field of abdominal organ donation. It is a step-by-step guide with photographs and drawings with clear explanations highlighting pitfalls. The book quickly and easily guides the reader through the difficult steps during organ procurement. It is mainly illustration-based, without much text, and covers surgical technical mistakes and organ damage.
Download or read book Transport Organs written by G. Giebisch and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Book Synopsis How Death Becomes Life by : Joshua Mezrich
Download or read book How Death Becomes Life written by Joshua Mezrich and published by . This book was released on 2020 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A beautifully written and compelling memoir of a largely unexplored area of medicine: transplant surgery. Leading transplant surgeon Dr Joshua Mezrich creates life from loss, moving organs from one body to another. In this intimate, profoundly moving work, he examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the stories of his own patients. Gripping and evocative, How Death Becomes Life takes us inside the operating room and presents the stark dilemmas that transplant surgeons must face daily: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? The human story behind the most exceptional medicine of our time, Mezrich's riveting book is a poignant reminder that a life lost can also offer the hope of a new beginning.
Book Synopsis Contemporary Bioethics by : Mohammed Ali Al-Bar
Download or read book Contemporary Bioethics written by Mohammed Ali Al-Bar and published by Springer. This book was released on 2015-05-27 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the common principles of morality and ethics derived from divinely endowed intuitive reason through the creation of al-fitr' a (nature) and human intellect (al-‘aql). Biomedical topics are presented and ethical issues related to topics such as genetic testing, assisted reproduction and organ transplantation are discussed. Whereas these natural sources are God’s special gifts to human beings, God’s revelation as given to the prophets is the supernatural source of divine guidance through which human communities have been guided at all times through history. The second part of the book concentrates on the objectives of Islamic religious practice – the maqa' sid – which include: Preservation of Faith, Preservation of Life, Preservation of Mind (intellect and reason), Preservation of Progeny (al-nasl) and Preservation of Property. Lastly, the third part of the book discusses selected topical issues, including abortion, assisted reproduction devices, genetics, organ transplantation, brain death and end-of-life aspects. For each topic, the current medical evidence is followed by a detailed discussion of the ethical issues involved.
Book Synopsis Anatomy and Physiology by : J. Gordon Betts
Download or read book Anatomy and Physiology written by J. Gordon Betts and published by . This book was released on 2013-04-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Organs-on-chips by : Yu-suke Torisawa
Download or read book Organs-on-chips written by Yu-suke Torisawa and published by MDPI. This book was released on 2020-05-27 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within microfluidic devices. Since the physiological microenvironments in living systems are mostly microfluidic in nature, the use of microfluidic devices facilitates engineering cellular microenvironments; the microfluidic devices allow for control of local chemical gradients and dynamic mechanical forces, which play important roles in cellular viability and function. The organ-on-chip microdevices have great potential to promote drug discovery and development, to model human physiology and disease, and to replace animal models for efficacy and toxicity testing. Recently, induced pluripotent stem (iPS) cells have been leveraged to develop organs-on-chips, which enable various types of organ models and disease models not possible with primary cells and cell lines. This Special Issue seeks to showcase research papers, short communications, and review articles that focus on: (1) microdevices to mimic or control cellular microenvironment; (2) microdevices to evaluate interactions between different organ models; (3) microdevices to maintain iPS cells or iPSC-derived cells; and (4) sensors and techniques to evaluate drug efficacy or toxicity.
Download or read book Transport Organs written by and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Pharmaceutical Applications of Cell and Tissue Culture to Drug Transport by : Glynn Wilson
Download or read book Pharmaceutical Applications of Cell and Tissue Culture to Drug Transport written by Glynn Wilson and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there have been rapid advances in the growth and differentiation of mammalian cells in culture. This has led to increasing use of such in vitro systems in a wide variety of studies on fundamental aspects of cell structure and function, including normal growth and metabolism, mechanisms of differentiation and oncogenesis, mechanisms of protein and membrane synthesis and cell polarity. Recent advances in our ability to grow cells, including human cells, on permeable supports, to generate confluent cellular barriers with the morphological polarity corresponding to their in vivo counterparts has greatly facilitated such studies. In particular these new techniques have led to an increasing interest in the use of cell and tissue culture systems as a means for examining the transport of drugs across epithelial and endothelial barriers. An obvious question is whether these new in vitro methodologies will provide convenient systems that can substitute for and replace animal models. Various research groups both in academia and in the pharmaceutical industry have been investigating these types of methodologies in order to develop convenient well characterized systems that can be used to examine basic aspects of transcellular transport and to evaluate the permeability of drug molecules and delivery systems. Of particular note is use of confluent cell layers to study the transport of large molecules such as peptides and proteins produced through recombinant DNA technology.
Download or read book Transport Organs written by G. Giebisch and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Science of Grapevines by : Markus Keller
Download or read book The Science of Grapevines written by Markus Keller and published by Academic Press. This book was released on 2015-02-02 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Science of Grapevines: Anatomy and Physiology is an introduction to the physical structure of the grapevine, its various organs, their functions and their interactions with the environment. Beginning with a brief overview of the botanical classification (including an introduction to the concepts of species, cultivars, clones, and rootstocks), plant morphology and anatomy, and growth cycles of grapevines, The Science of Grapevines covers the basic concepts in growth and development, water relations, photosynthesis and respiration, mineral uptake and utilization, and carbon partitioning. These concepts are put to use to understand plant-environment interactions including canopy dynamics, yield formation, and fruit composition, and concludes with an introduction to stress physiology, including water stress (drought and flooding), nutrient deficiency and excess, extreme temperatures (heat and cold), and the impact and response to of other organisms. Based on the author’s years of teaching grapevine anatomy as well as his research experience with grapevines and practical experience growing grapes, this book provides an important guide to understanding the entire plant. Chapter 7 broken into two chapters, now "Environmental Constraints and Stress Physiology and Chapter 8 "Living with Other Organisms" to better reflect specific concepts Integration of new research results including: Latest research on implementing drip irrigation to maximize sugar accumulation within grapes Effect of drought stress on grapevine’s hydraulic system and options for optimum plant maintenance in drought conditions The recently discovered plant hormone – strigolactones – and their contribution of apical dominance that has suddenly outdated dogma on apical dominance control Chapter summaries added Key literature references missed in the first edition as well as references to research completed since the 1e publication will be added
Book Synopsis Tissue Engineering and Artificial Organs by : Joseph D. Bronzino
Download or read book Tissue Engineering and Artificial Organs written by Joseph D. Bronzino and published by CRC Press. This book was released on 2006-05-01 with total page 1328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last century, medicine has come out of the "black bag" and emerged as one of the most dynamic and advanced fields of development in science and technology. Today, biomedical engineering plays a critical role in patient diagnosis, care, and rehabilitation. As such, the field encompasses a wide range of disciplines, from biology and physiology to material science and nanotechnology. Reflecting the enormous growth and change in biomedical engineering during the infancy of the 21st century, The Biomedical Engineering Handbook enters its third edition as a set of three carefully focused and conveniently organized books. Reviewing applications at the leading edge of modern biomedical engineering, Tissue Engineering and Artificial Organs explores transport phenomena, biomimetics systems, biotechnology, prostheses, artificial organs, and ethical issues. The book features approximately 90% new material in the tissue engineering section, integrates coverage of life sciences with a new section on molecular biology, and includes a new section on bionanotechnology. Prominent leaders from around the world share their expertise in their respective fields with many new and updated chapters. New technologies and methods spawned by biomedical engineering have the potential to improve the quality of life for everyone, and Tissue Engineering and Artificial Organs sheds light on the tools that will enable these advances.
Book Synopsis Transport Phenomena in Biomedical Engineering: Artifical organ Design and Development, and Tissue Engineering by : Kal Sharma
Download or read book Transport Phenomena in Biomedical Engineering: Artifical organ Design and Development, and Tissue Engineering written by Kal Sharma and published by McGraw Hill Professional. This book was released on 2010-07-21 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Cutting-Edge Guide to Applying Transport Phenomena Principles to Bioengineering Systems Transport Phenomena in Biomedical Engineering: Artificial Order Design and Development and Tissue Engineering explains how to apply the equations of continuity, momentum, energy, and mass to human anatomical systems. This authoritative resource presents solutions along with term-by-term medical significance. Worked exercises illustrate the equations derived, and detailed case studies highlight real-world examples of artificial organ design and human tissue engineering. Coverage includes: Fundamentals of fluid mechanics and principles of molecular diffusion Osmotic pressure, solvent permeability, and solute transport Rheology of blood and transport Gas transport Pharmacokinetics Tissue design Bioartificial organ design and immunoisolation Bioheat transport 541 end-of-chapter exercises and review questions 106 illustrations 1,469 equations derived from first principles
Book Synopsis Tissues and Organs by : G. A. Chauvet
Download or read book Tissues and Organs written by G. A. Chauvet and published by Elsevier. This book was released on 2013-09-11 with total page 555 pages. Available in PDF, EPUB and Kindle. Book excerpt: Theoretical Systems in Biology: Hierarchical and Functional Integration, Volume II: Tissues and Organs discusses the phenomenology of physiological mechanisms. The book is comprised 10 chapters that are organized into two parts. The first part covers topics about the cell and its environment, such as cell membrane structure, mechanisms of membrane transport, and cell excitability. The second part deals with the mechanisms of physiological functions, which include the metabolic system, the respiratory system, and the renal system. The book will be of great use to researchers and professionals whose work requires a good understanding of human physiology.
Book Synopsis Monitoring in Anesthesia and Perioperative Care by : David L. Reich
Download or read book Monitoring in Anesthesia and Perioperative Care written by David L. Reich and published by Cambridge University Press. This book was released on 2011-08-08 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monitoring in Anesthesia and Perioperative Care is a practical and comprehensive resource documenting the current art and science of perioperative patient monitoring, addressing the systems-based practice issues that drive the highly regulated health care industry of the early twenty-first century. Initial chapters cover the history, medicolegal implications, validity of measurement and education issues relating to monitoring. The core of the book addresses the many monitoring modalities, with the majority of the chapters organized in a systematic fashion to describe technical concepts, parameters monitored, evidence of utility complications, credentialing and monitoring standards, and practice guidelines. Describing each device, technique and principle of clinical monitoring in an accessible style, Monitoring in Anesthesia and Perioperative Care is full of invaluable advice from the leading experts in the field, making it an essential tool for every anesthesiologist.
