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Refractory Depression Current Strategies And Future Directions
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Book Synopsis Electroconvulsive Therapy in Children and Adolescents by : Neera Ghaziuddin
Download or read book Electroconvulsive Therapy in Children and Adolescents written by Neera Ghaziuddin and published by Oxford University Press. This book was released on 2013-12 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a pioneering book about the use of ECT in adolescents who are diagnosed with severe, disabling psychiatric disorders or fail conventional treatment. Included are a review of the literature, firsthand experience of the authors and case descriptions making it an invaluable guide to treatment.
Book Synopsis Refractory Depression, Current Strategies and Future Directions by : Willem A. Nolen
Download or read book Refractory Depression, Current Strategies and Future Directions written by Willem A. Nolen and published by . This book was released on 1994-06-30 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Refractory Depression Current Strategies and Future Directions Edited by Willem A. Nolen Psychiatric Centre Bloemendaal, The Hague, The Netherlands Joseph Zohar The Chaim Sheba Medical Center, Israel Steven P. Roose New York State Psychiatric Institute, New York, USA Jay D. Amsterdam Department of Psychiatry, University of Pennsylvania, USA As many as 30% of depressed patients fail to respond to conventional antidepressant therapy, and 15% may develop a chronic unremitting depression. A variety of pharmacological, biochemical and clinical factors may contribute to this situation. However, even after making allowances for these variables, a substantial number of patients remain refractory to treatment. This text offers the clinician a broad insight into the problem of refractory depression, providing new information on the adequacy of standard treatments and the major alternatives as well as reviews of a number of other possible alternatives for those patients remaining depressed. Finally, some future directions and developments are presented which may soon lead to a better understanding of the problem of refractory depression. Written by an international field of authors, the book will be of value to all researchers and clinicians in the field of psychiatry.
Book Synopsis Pharmacotherapy For Depression And Treatment-resistant Depression by : George I Papakostas
Download or read book Pharmacotherapy For Depression And Treatment-resistant Depression written by George I Papakostas and published by World Scientific. This book was released on 2010-04-28 with total page 726 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique ground-breaking work, authored by renowned Harvard-based researchers G I Papakostas and M Fava, represents, by far, the most comprehensive compilation to date of medical studies and reports involving the use of antidepressants for the treatment of major depressive disorder, one of the most prevalent and devastating medical illnesses afflicting mankind today. Given the breadth of the scientific literature focusing on the use of antidepressants for major depressive disorder, this work represents an invaluable tool for clinicians as well as scientists in search of a reference manual to help guide them through the field. The book is organized into four parts; each part focusing on a separate theme that will facilitate the reader to precisely access particular information of interest, whether be it clinical or scientific in nature. Each part is then sub-divided into several thematic chapters, which are enriched with tables and figures citing results from the most influential studies in the field. Finally, clinical and research “pearls” are listed throughout the book in bullet-point fashion to help summarize the available knowledge-base in a user-friendly format.
Book Synopsis Ketamine for Treatment-Resistant Depression by : Sanjay J. Mathew
Download or read book Ketamine for Treatment-Resistant Depression written by Sanjay J. Mathew and published by Springer. This book was released on 2016-11-25 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research.
Book Synopsis Managing Treatment-Resistant Depression by : Joao Luciano de Quevedo
Download or read book Managing Treatment-Resistant Depression written by Joao Luciano de Quevedo and published by Elsevier. This book was released on 2022-04-04 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD. Defines Treatment-Resistant Depression and Staging Treatment Intensity Includes Treatment-Resistant Depression options for children, adolescents, geriatrics, during pregnancy, and during post-partum and menopause transitions Discusses the use of Ketamine and Esketamine for treatment-resistant depression
Author :American Psychiatric Association Publisher :American Psychiatric Pub ISBN 13 :1585627879 Total Pages :364 pages Book Rating :4.5/5 (856 download)
Book Synopsis The Practice of Electroconvulsive Therapy by : American Psychiatric Association
Download or read book The Practice of Electroconvulsive Therapy written by American Psychiatric Association and published by American Psychiatric Pub. This book was released on 2008-08-13 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the development of pharmacoconvulsive therapy in 1934 and of electroconvulsive therapy (ECT) in 1938, ECT has proven far more valuable than just the intervention of last resort. In comparison with psychotropic medications, we now know that ECT can act more effectively and more rapidly, with substantial clinical improvement that is often seen after only a few treatments. This is especially true for severely ill patients -- those with severe major depression with psychotic features, acute mania with psychotic features, or catatonia. For patients who are physically debilitated, elderly, or pregnant, ECT is also safer than psychotropic medications. The findings of the American Psychiatric Association (APA) Task Force on ECT were published by the APA in 1990 as the first edition of The Practice of Electroconvulsive Therapy, inaugurating the development of ECT guidelines by groups both within the United States and internationally. Since then, advances in the use of this technically demanding treatment prompted the APA to mandate a second edition. The updated format of this second edition presents background information followed by a summary of applicable recommendations for each chapter. This close integration of the recommendations with their justifications makes the material easy to read, understand, and use. To further enhance usability, recommendations critical to the safe, effective delivery of treatment are marked with the designation "should" to distinguish them from recommendations that are advisable but nonessential (with the designations "encouraged," "suggested," "considered"). The updated content of this second edition, which spans indication for use of ECT, patient evaluation, side effects, concurrent medications, consent procedures (with sample consent forms and patient information booklet), staffing, treatment administration, monitoring of outcome, management of patients following ECT, and documentation, as well as education, and clinical privileging. This volume reflects not only the wide expertise of its contributors, but also involved solicitation of input from a variety of other sources, including applicable medical professional organizations, individual experts in relevant fields, regulatory bodies, and major lay mental health organizations. In addition, the bibliography of this second edition is based upon an exhaustive search of the clinical ECT literature over the past decade and contains more than four times the original number of citations. Complemented by extensive annotations and useful appendixes, this remarkably comprehensive yet practical overview will prove an invaluable resource for practitioners and trainees in psychiatry and related disciplines.
Download or read book Rapid Acting Antidepressants written by and published by Academic Press. This book was released on 2020-06-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Book Synopsis Treatment-Resistant Mood Disorders by : Jay D. Amsterdam
Download or read book Treatment-Resistant Mood Disorders written by Jay D. Amsterdam and published by Cambridge University Press. This book was released on 2001-06-28 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely book assesses all aspects of treatment-resistant depression and will be invaluable to professionals.
Book Synopsis A Clinical Guide to Transcranial Magnetic Stimulation by : Paul E. Holtzheimer
Download or read book A Clinical Guide to Transcranial Magnetic Stimulation written by Paul E. Holtzheimer and published by Oxford University Press. This book was released on 2014-02-21 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Clinical Guide serves as a reference tool for clinicians in the administration of transcranial magnetic stimulation (TMS) for neuropsychiatric disorders. The primary intent of this Guide is to focus on the clinical applications of TMS and to offer detailed information on the safe and effective administration of TMS with consideration of the neurophysiological effects particularly in relation to safety, targeting specific cortical areas and practical issues such as the length of treatment sessions and the durability of the TMS response. The Guide focuses on the evidenced based literature and utilizes this literature to inform specific recommendations on the use of rTMS in a clinical setting. The efficacy and safety of TMS for neuropsychiatric disorders, including its use in special populations, such as the elderly, will be reviewed to facilitate clinical decision-making. The Guide will also outline setting up a TMS service including practical issues such as considerations for the qualifications of the person administering the treatment, the use of concomitant medications, what equipment is necessary to have in the treatment room and monitoring the outcomes to treatment. The Guide is intended to be a practical reference for the practicing clinician in the safe and effective administration of TMS.
Book Synopsis Treating Resistant Depression by : Joseph Zohar
Download or read book Treating Resistant Depression written by Joseph Zohar and published by . This book was released on 1987 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Shock Therapy written by Edward Shorter and published by Rutgers University Press. This book was released on 2007 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Shock therapy is making a comeback today in the treatment of serious mental illness. Despite its reemergence as a safe and effective psychiatric tool, however, it continues to be shrouded by a longstanding negative public image, not least due to films such as the classic One Flew over the Cuckoo's Nest, where the inmate of a psychiatric clinic (played by Jack Nicholson) is subjected to electro-shock to curb his rebellious behavior. Beyond its vilification in popular culture, the stereotype of convulsive therapy as a dangerous and inhumane practice is fuelled by professional posturing and public misinformation. Electroconvulsive therapy, or ECT, has in the last thirty years been considered a method of last resort in the treatment of debilitating depression, suicidal ideation, and other forms of mental illness. Yet, ironically, its effectiveness in treating these patients would suggest it as a frontline therapy, bringing relief from acute symptoms and saving lives. Shock therapy is making a comeback today in the treatment of serious mental illness. Despite its reemergence as a safe and effective psychiatric tool, however, it continues to be shrouded by a longstanding negative public image, not least due to films such as the classic One Flew over the Cuckoo's Nest, where the inmate of a psychiatric clinic (played by Jack Nicholson) is subjected to electro-shock to curb his rebellious behavior. Beyond its vilification in popular culture, the stereotype of convulsive therapy as a dangerous and inhumane practice is fuelled by professional posturing and public misinformation. Electroconvulsive therapy, or ECT, has in the last thirty years been considered a method of last resort in the treatment of debilitating depression, suicidal ideation, and other forms of mental illness. Yet, ironically, its effectiveness in treating these patients would suggest it as a frontline therapy, bringing relief from acute symptoms and saving lives. -- Provided by publisher.
Book Synopsis Clinical Handbook for the Management of Mood Disorders by : J. John Mann
Download or read book Clinical Handbook for the Management of Mood Disorders written by J. John Mann and published by Cambridge University Press. This book was released on 2013-05-09 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a one-stop evidence-based guide to the management of all types of mood disorders.
Book Synopsis Ketamine for Treatment-Resistant Depression by : Gustavo H. Vazquez
Download or read book Ketamine for Treatment-Resistant Depression written by Gustavo H. Vazquez and published by Academic Press. This book was released on 2020-09-16 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. - Provides efficacy research on ketamine as a treatment for depression - Identifies best practices for clinical use, both long-term and acute - Discusses the molecular mechanisms and neurobiology of action
Book Synopsis Clinician's Quick Guide to Interpersonal Psychotherapy by : Myrna Weissman
Download or read book Clinician's Quick Guide to Interpersonal Psychotherapy written by Myrna Weissman and published by Oxford University Press. This book was released on 2007-02-15 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Clinician's Quick Guide to Interpersonal Psychotherapy is for busy clinicians who want to learn interpersonal psychotherapy (IPT), but who lack the time to read a more detailed manual or to attend a course. The book is also intended for clinicians who have had some exposure to IPT in workshops or supervision and want a reference book for their practice.
Book Synopsis Treatment-Resistant Depression by : Siegfried Kasper
Download or read book Treatment-Resistant Depression written by Siegfried Kasper and published by John Wiley & Sons. This book was released on 2013-04-15 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment-resistant Depress Successful management of patients with treatment-resistant depression requires a thorough understanding of the biological basis for both the depression and its failure to respond to standard treatments. This book clearly and succinctly summarizes the latest scientific research and its applications in clinical practice. A first step is a clear definition of what constitutes treatment-resistant depression so that clinical trials and other studies are using common criteria, enabling comparison and meta-analysis of their outcomes. The opening chapter reviews definitions and predictors of treatment-resistant depression originating from different fields and discusses their usefulness in clinical practice and clinical research. The next chapter proposes a new definition, adapting terminology from medicine. Biological classification requires identification of genetic risk factors and gene variants have been identified as accounting for 50% of the variance in the clinical outcomes of antidepressant treatments. Chapter 3 describes several genes already associated with treatment-resistant depression and, while further work is needed to translate findings into clinical recommendations, suggests that genetic prediction of treatment resistance could become a widespread clinical reality within a few years. Most patients with treatment-resistant depression will be treated pharmacologically, so three chapters review the latest evidence for pharmacological best practice in switching strategies for antidepressants, the role of antipsychotics and augmentation strategies to complement lithium. There are two major alternatives to pharmacotherapy: neuromodulation and psychotherapy. The brain intervention chapter summarizes clinical research and experience with electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, deep brain stimulation and magnetic seizure therapy. The final chapter reviews the literature pertaining to the effectiveness of various forms of psychotherapy in patients who have not responded to antidepressant pharmacotherapy, explaining that patients who have not responded to one or two trials of antidepressant medication have a 30%-50% chance of responding to a focused psychotherapy. It proposes indications for psychotherapy in treatment-resistant depression and summarizes general therapeutic principles. Essential reading for all psychiatrists managing patients with this distressing disorder.
Book Synopsis The Treatment of Bipolar Disorder by : André F. Carvalho
Download or read book The Treatment of Bipolar Disorder written by André F. Carvalho and published by Oxford University Press. This book was released on 2017-03-01 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar disorder is a chronic and debilitating mental illness affecting a significant proportion of the world's population. It is associated with significant impairments in health-related quality of life and psychosocial functioning, and has significant illness-related morbidity and heightened mortality rates due to medical comorbidities and suicide. The management of this disorder requires a complex combination of pharmacological and psychosocial interventions which can be challenging for clinicians. Written by world experts in the field of bipolar disorder, The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions provides readers with a concise and comprehensive guide to the integrative management of bipolar disorder. This resource contains 31 chapters on the various management choices available, from both established and novel treatment areas, such as psychoeducation, psychotherapeutic interventions, neuromodulatory approaches and novel therapeutic targets. The complexity and diversity of the management choices available makes this a continually evolving field and necessitates forward thinking. By both discussing the current management of bipolar disorder, and the future developments available, this resource provides all clinicians working with patients with bipolar disorder an up-to-date and reflective guide to its management and what the future holds.
Book Synopsis Self-System Therapy for Depression by : Kari M. Eddington
Download or read book Self-System Therapy for Depression written by Kari M. Eddington and published by Oxford University Press. This book was released on 2017-12 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Self-System Therapy for Depression: Therapist Guide and Client Workbook provide a thorough description of Self-System Therapy (SST)-an approach to treating depression that helps decrease feelings of disappointment and failure and increase feelings of pride and accomplishment, by improving the process of self-regulation.
