Ketamine for Treatment-Resistant Depression

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Author :
Publisher : Springer
ISBN 13 : 3319429256
Total Pages : 155 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Ketamine for Treatment-Resistant Depression by : Sanjay J. Mathew

Download or read book Ketamine for Treatment-Resistant Depression written by Sanjay J. Mathew and published by Springer. This book was released on 2016-11-25 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants. Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research.

Ketamine for Treatment-Resistant Depression

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Author :
Publisher : Academic Press
ISBN 13 : 0128210346
Total Pages : 170 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Ketamine for Treatment-Resistant Depression by : Gustavo H. Vazquez

Download or read book Ketamine for Treatment-Resistant Depression written by Gustavo H. Vazquez and published by Academic Press. This book was released on 2020-09-16 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. Provides efficacy research on ketamine as a treatment for depression Identifies best practices for clinical use, both long-term and acute Discusses the molecular mechanisms and neurobiology of action

Ketamine for Depression

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Author :
Publisher : Xlibris Corporation
ISBN 13 : 1503509532
Total Pages : 222 pages
Book Rating : 4.5/5 (35 download)

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Book Synopsis Ketamine for Depression by : Dr. Stephen J. Hyde

Download or read book Ketamine for Depression written by Dr. Stephen J. Hyde and published by Xlibris Corporation. This book was released on 2015-09-04 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the unacceptably high rates of suffering, disability and premature death experienced by people with treatment-resistant depression and the surprisingly low rates of problems arising from the use of ketamine to treat the disorder, this is a therapy that all patients and their doctors should be discussing. This book summarises the research that has been carried out into ketamine for the treatment of depression over the past 15 years and, most importantly, describes different ways of using ketamine that are both practical and cost–effective. Currently most ketamine therapy is given intravenously in specialised clinics at considerable expense, but the author has successfully treated patients with low-dose sublingual ketamine and his patients have been able to safely take this at home. Profits from the sales of this book will assist further research into the use of ketamine for the treatment of depression.

Rapid Acting Antidepressants

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Author :
Publisher : Academic Press
ISBN 13 : 0128201908
Total Pages : 404 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Rapid Acting Antidepressants by :

Download or read book Rapid Acting Antidepressants written by and published by Academic Press. This book was released on 2020-06-29 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Treatment-resistant Mood Disorders

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Author :
Publisher : Oxford Psychiatry Library
ISBN 13 : 0198707991
Total Pages : 175 pages
Book Rating : 4.1/5 (987 download)

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Book Synopsis Treatment-resistant Mood Disorders by : André Carvalho

Download or read book Treatment-resistant Mood Disorders written by André Carvalho and published by Oxford Psychiatry Library. This book was released on 2015 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. Providing a concise view of the current definitions, assessment and evidence-based management of such disorders, this work reviews novel therapeutic targets, which may enhance the future therapeutic armamentarium of clinicians.

Managing Treatment-Resistant Depression

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Author :
Publisher : Academic Press
ISBN 13 : 0128240687
Total Pages : 614 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Managing Treatment-Resistant Depression by : Joao Quevedo

Download or read book Managing Treatment-Resistant Depression written by Joao Quevedo and published by Academic Press. This book was released on 2022-03-31 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt: Managing Treatment-Resistant Depression: Road to Novel Therapeutics defines TRD for readers, discussing the clinical and epidemiological predictors, economic burden and neurobiological factors. In addition, staging methods for treatment resistance are fully covered in this book, including serotonin specific reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, other classes of antidepressants, including tricyclic antidepressants and monoamine oxidase inhibitors, augmentation strategies, and newer antidepressant treatments like ketamine and esketamine. In addition, evidence supporting the use of psychotherapies and neuromodulation strategies are also reviewed. Written by top experts in the field, this book is the first of its kind to review all methods of treatment for TRD. Defines Treatment-Resistant Depression and Staging Treatment Intensity Includes Treatment-Resistant Depression options for children, adolescents, geriatrics, during pregnancy, and during post-partum and menopause transitions Discusses the use of Ketamine and Esketamine for treatment-resistant depression

Natural Medications for Psychiatric Disorders

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781767620
Total Pages : 386 pages
Book Rating : 4.7/5 (676 download)

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Book Synopsis Natural Medications for Psychiatric Disorders by : David Mischoulon

Download or read book Natural Medications for Psychiatric Disorders written by David Mischoulon and published by Lippincott Williams & Wilkins. This book was released on 2008 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated for its Second Edition, this book is the only reference to focus exclusively on natural medications in psychiatry. Eminent psychiatrists from the Massachusetts General Hospital and other leading institutions examine current scientific and clinical data on the applications, effectiveness, and safety of natural psychotropics and acupuncture. Quick-reference tabular appendices list indications, contraindications, dosages, combinations, and drug-drug interactions for each remedy. This edition includes brand-new chapters on acupuncture, homeopathy, and therapies for substance dependence and weight management. The chapter on polypharmacy and side effect management addresses the growing issue of drug-drug interactions. New introductory chapters discuss complementary and alternative medicine in society and examine research limitations and quality assurance issues.

IV Ketamine Infusion Therapy for Depression

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Author :
Publisher :
ISBN 13 : 9781736892510
Total Pages : 118 pages
Book Rating : 4.8/5 (925 download)

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Book Synopsis IV Ketamine Infusion Therapy for Depression by : Frank Ligons

Download or read book IV Ketamine Infusion Therapy for Depression written by Frank Ligons and published by . This book was released on 2021-04-15 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many depressed patients are "treatment-resistant," unable to find relief. Ketamine Infusions help TWO-THIRDS of these cases.

Ketamine

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Author :
Publisher : Springer
ISBN 13 : 9789811529047
Total Pages : 189 pages
Book Rating : 4.5/5 (29 download)

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Book Synopsis Ketamine by : Kenji Hashimoto

Download or read book Ketamine written by Kenji Hashimoto and published by Springer. This book was released on 2021-03-06 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse. The first part of the book focuses on the evidence regarding ketamine abuse, with specific reference to Asian countries, and discusses countermeasures and complication management. It then addresses the mechanisms underlying the antidepressant and side effects of ketamine, which have remained elusive, describing and discussing important new research findings. Further, it explains insights gained from whole brain imaging in rodents and from behavioral pharmacology, and presents evidence regarding the role of gut microbiota, the NMDA receptor GluN2D subunit, and the lateral habenula in the actions of ketamine. These advances form the basis for the safer use of ketamine in patients with treatment-resistant depression and are expected to lead to the development of new antidepressants.

Curing Stubborn Depression

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Author :
Publisher : Hatherleigh Press
ISBN 13 : 1578269385
Total Pages : 250 pages
Book Rating : 4.5/5 (782 download)

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Book Synopsis Curing Stubborn Depression by : Paul Fitzgerald

Download or read book Curing Stubborn Depression written by Paul Fitzgerald and published by Hatherleigh Press. This book was released on 2023-11-14 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hope and help arrives in this psychiatrist's preview of emerging and breakthrough therapies for treating more severe, treatment-resistant depression. Over 280 million individuals worldwide suffer from depression every year, with many turning to potent antidepressants and drastic lifestyle changes to help manage their condition and improve their quality of life. But what if these methods don’t work? What if, despite all efforts, an individual continues to suffer? Stubborn, treatment-resistant depression dramatically reduces a person’s quality of life while providing them with seemingly few options for relief. Curing Stubborn Depression seeks to not only explain the underlying causes of this pervasive form of depressive disorder, but to shine light on a number of non-traditional treatments, new therapies and clinical developments—including ECT, transcranial magnetic stimulation, bright light therapy, ketamine and more—offering hope to those who feel like they have none. The field of depression treatment is rapidly evolving and constantly changing, meaning it can be difficult to keep up with new therapies and clinical developments. Curing Stubborn Depression delves into these emergent treatments, many of which are transforming how this condition is managed—and offering hope to those who feel like they have none.

The Ketamine Papers

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Author :
Publisher :
ISBN 13 : 9780998276502
Total Pages : 420 pages
Book Rating : 4.2/5 (765 download)

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Book Synopsis The Ketamine Papers by : Phil Wolfson

Download or read book The Ketamine Papers written by Phil Wolfson and published by . This book was released on 2016-11 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ketamine Papers opens the door to a broad understanding of this medicine's growing use in psychiatry and its decades of history providing transformative personal experiences. Now gaining increasing recognition as a promising approach to the treatment of depression, posttraumatic stress disorder (PTSD), and other psychological conditions, ketamine therapies offer new hope for patients and clinicians alike. With multiple routes of administration and practices ranging from anesthesia to psychotherapy, ketamine medicine is a diverse and rapidly growing field. The Ketamine Papers clarifies the issues and is an inspiring introduction to this powerful tool for healing and transformation--from its early use in the 1960s to its emerging role in the treatment of depression, suicidality, and other conditions. This comprehensive volume is the ideal introduction for patients and clinicians alike, and for anyone interested in the therapeutic and transformative healing power of this revolutionary medicine.

Antidepressants

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Author :
Publisher : Springer
ISBN 13 : 3030109496
Total Pages : 442 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Antidepressants by : Matthew Macaluso

Download or read book Antidepressants written by Matthew Macaluso and published by Springer. This book was released on 2019-05-31 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.

Handbook of Depression

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Author :
Publisher :
ISBN 13 :
Total Pages : 1112 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Handbook of Depression by : Ernest Edward Beckham

Download or read book Handbook of Depression written by Ernest Edward Beckham and published by . This book was released on 1985 with total page 1112 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Treating Resistant Depression

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Author :
Publisher :
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Treating Resistant Depression by : Joseph Zohar

Download or read book Treating Resistant Depression written by Joseph Zohar and published by . This book was released on 1987 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Cognition in Major Depressive Disorder

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Publisher : OUP Oxford
ISBN 13 : 0191002623
Total Pages : 128 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis Cognition in Major Depressive Disorder by : Roger S. McIntyre

Download or read book Cognition in Major Depressive Disorder written by Roger S. McIntyre and published by OUP Oxford. This book was released on 2014-05-08 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the Oxford Psychiatry Library (OPL) series, Cognition in Major Depressive Disorder provides a succinct summary of cognitive deficits reported in patients with major depressive disorder (MDD) with a particular focus on aspects of measurement, underlying disease pathophysiology, implications for treatment and prevention. This book also provides readers an opportunity for clinical-based assessment of cognition and recommendations for how cognitive measurement and treatment is positioned in the management of individuals with mood disorders.

Kainic Acid as a Tool in Neurobiology

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Author :
Publisher : Lippincott Williams & Wilkins
ISBN 13 :
Total Pages : 296 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Kainic Acid as a Tool in Neurobiology by : Edith G. McGeer

Download or read book Kainic Acid as a Tool in Neurobiology written by Edith G. McGeer and published by Lippincott Williams & Wilkins. This book was released on 1978 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Stereotactic and Functional Neurosurgery

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Author :
Publisher : Springer Nature
ISBN 13 : 3030349063
Total Pages : 563 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Stereotactic and Functional Neurosurgery by : Nader Pouratian

Download or read book Stereotactic and Functional Neurosurgery written by Nader Pouratian and published by Springer Nature. This book was released on 2020-02-28 with total page 563 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents a comprehensive and state-of the-art approach to stereotactic and functional neurosurgery. Overarching sections include achieving stereotactic precision, defining trajectories and targets, the biophysics of stereotactic therapies, diseases and targets, and the future of functional neurosurgery. Each section is designed to be inclusive of all relevant topics, serving as an unbiased resource to new clinicians in this field or established clinicians that are aiming to better understand complementary methods. Importantly, each section and the associated chapters can be used by basic and translational scientists as well as engineers and industry to better understand and deliver innovation to the field. Chapters within each section methodically analyze traditional and recently emerging concepts and techniques; address underlying principles with examples drawn from specific diseases and applications; and cover patient selection, target selection, available stereotactic methods, nuanced surgical methods, and clinical evidence across treatment options. Written by experts in each area, Stereotactic and Functional Neurosurgery is a definitive guide to the latest developments in stereotactic targeting, electrode implantation, surgical treatment of neurological and psychiatric disorders, the renaissance of stereotactic lesions, and the frontier of restorative neurosurgery for a variety of disorders that have no other therapeutic options.