Rat Experimental Transplantation Surgery

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Publisher : Springer
ISBN 13 : 3319145592
Total Pages : 257 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Rat Experimental Transplantation Surgery by : Peter Girman

Download or read book Rat Experimental Transplantation Surgery written by Peter Girman and published by Springer. This book was released on 2015-11-16 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to describe tested microsurgical procedures of kidney, pancreas, islets, heat, liver and small bowel transplantation. All procedures written in the book are used in our experimental research laboratory and their description will be provided by an experienced researcher. The book is organized into ‘General’ and ‘Specific’ sections. The ‘General’ section will include principles, doses and available drugs for rat anaesthesia, the surgical anatomy of the rat, a brief review of immunosuppressant’s used in rat models, a description of basic surgical techniques and blood sampling. The ‘Specific’ section will include a description of the rat model with the appropriate organ failure relevant to the organ transplantation, which will be followed by a detailed description of the surgical procedure with high quality pictures of key steps. Each chapter will describe ‘tips and tricks’ including practical advice and recommendations.

Rat Experimental Transplantation Surgery

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Author :
Publisher :
ISBN 13 : 9783319145600
Total Pages : pages
Book Rating : 4.1/5 (456 download)

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Book Synopsis Rat Experimental Transplantation Surgery by : Peter Girman

Download or read book Rat Experimental Transplantation Surgery written by Peter Girman and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the book is to describe tested microsurgical procedures of kidney, pancreas, islets, heat, liver and small bowel transplantation. All procedures written in the book are used in our experimental research laboratory and their description will be provided by an experienced researcher. The book is organized into 'General' and 'Specific' sections. The 'General' section will include principles, doses and available drugs for rat anaesthesia, the surgical anatomy of the rat, a brief review of immunosuppressant's used in rat models, a description of basic surgical techniques and blood sampling. The 'Specific' section will include a description of the rat model with the appropriate organ failure relevant to the organ transplantation, which will be followed by a detailed description of the surgical procedure with high quality pictures of key steps. Each chapter will describe 'tips and tricks' including practical advice and recommendations.

Microsurgical Models in Rats for Transplantation Research

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642616577
Total Pages : 412 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Microsurgical Models in Rats for Transplantation Research by : Arnulf Thiede

Download or read book Microsurgical Models in Rats for Transplantation Research written by Arnulf Thiede and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preclinical experimental transplantation research that is based on microsurgical models in rats fulfills two indispensable conditions for modern organ transplanta tion research: Almost all organ grafts can be performed on the rat with an amount of technical effort that is still justifiable. Thus transplantation models that are analogous to human organ transplantation can be developed, tested, and evaluated. This fulfills a necessary condition from the standpoint of surgery. With the species rat, we have a great variety of genetically different inbred strains. From the immunological point of view this is an indispensable prerequisite for the investigation of preclinical transplantation models that can be expected to produce controllable, reproducible results. In vivo experimental results can be supplemented by and correlated to in vitro tests. Lately these experimental results are being greatly expanded and more precisely defined by the application of immunohistological methods that have been established recently in Kiel. In this book we hope to present a cross section of the microsurgical models in use today and of current immunological and immunohistological models. Furthermore, we wish to record the present state of microsurgical organ transplantation research and to show its relationship to the current state and development of clinical organ transplantation. A special aspect of our Kiel research group is the long-term, well-functioning, interdisciplinary cooperation between surgery, immunology, and pathology. Through this cooperation we attempt to provide an atmosphere in which theoretical and practical viewpoints can mutually influence each other.

Organtransplantation in Rats and Mice

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Publisher : Springer Science & Business Media
ISBN 13 : 3642721400
Total Pages : 655 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Organtransplantation in Rats and Mice by : Wolfgang Timmermann

Download or read book Organtransplantation in Rats and Mice written by Wolfgang Timmermann and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: Main focus of the new book will be the description and discussion of rat and mouse models for organ transplantation. Various microsurgical techniques will be presented which allow transplantation of functional organs in syngeneic systems. In particular, the extremely difficult methods necessary for organ transplantation in mice will be presented and evaluated. Besides these practical aspects the book will also cover the theoretical sides of organ transplantation like the immunobiology of allotransplantation. Special emphasis will be given to the resurgent field of xenotransplantation. The results from xenograft models developed in the recent years using rats or mice will be reviewed and their impact on future human xenotransplantation will be discussed.

Experimental Liver Transplantation

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Author :
Publisher : CRC Press
ISBN 13 : 0429558651
Total Pages : 168 pages
Book Rating : 4.4/5 (295 download)

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Book Synopsis Experimental Liver Transplantation by : Naoshi Kamada

Download or read book Experimental Liver Transplantation written by Naoshi Kamada and published by CRC Press. This book was released on 2019-06-04 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1988, Experimental Liver Transplantation is a helpful guide through the process of Liver Transplantation and how the surgical techniques have evolved over the years. Filled with references to the history of Liver transplantation, to the experimental procedures performed on rats. This is an essential guide to any students of surgery or professionals in their respective fields.

Experimental and Surgical Technique in the Rat

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Author :
Publisher :
ISBN 13 : 9780127388519
Total Pages : 382 pages
Book Rating : 4.3/5 (885 download)

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Book Synopsis Experimental and Surgical Technique in the Rat by : H. Bryan Waynforth

Download or read book Experimental and Surgical Technique in the Rat written by H. Bryan Waynforth and published by . This book was released on 1992 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of this Second Edition, twelve years after the first, attests to the timelessness of the techniques used in experimental work with the rat. However, scientific progress inevitably brings to light new ideas and procedures. In particular, considerable progress has been made in the use of new anesthetics and analgesics. A completely new chapter has been written on these with unique emphasis on the applicability to the rat. The very variable standards of surgery that existed in the past are placed in perspective in another new chapter, which makes recommendations more in keeping with the higher standards now demanded of animal experimentation. A variety of new techniques have been added throughout to expand the usefulness of the book, and more illustrations have been added to help in the execution of the various procedures. One of the greatest advances in the last twelve years is a greater appreciation for the well-being of experimental animals, and references to a more humane and refined approach have been made throughout this edition. This greater awareness of welfare issues demands that experimental animals be handled and used correctly and compassionately, with as little suffering as possible, and has led to a marked improvement in the attitude to proper training. This book is still the only source which provides a detailed and up-to-date compilation of illustrated experimental methods for work with the rat. It will continue to be an invaluable reference to specific information for laboratory workers and will help considerably in training new investigators in the proper and considerate use of this species. Key Features * All surgical techniques have been revised and updated * A new section on anesthesia and post-operative care has been included * Presents new techniques, particularly cannulation

Experimental and Surgical Technique in the Rat

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Author :
Publisher :
ISBN 13 : 9780127388502
Total Pages : 269 pages
Book Rating : 4.3/5 (885 download)

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Book Synopsis Experimental and Surgical Technique in the Rat by : H. B. Waynforth

Download or read book Experimental and Surgical Technique in the Rat written by H. B. Waynforth and published by . This book was released on 1980-01-01 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The publication of this Second Edition, twelve years after the first, attests to the timelessness of the techniques used in experimental work with the rat. However, scientific progress inevitably brings to light new ideas and procedures. In particular, considerable progress has been made in the use of new anesthetics and analgesics. A completely new chapter has been written on these with unique emphasis on the applicability to the rat. The very variable standards of surgery that existed in the past are placed in perspective in another new chapter, which makes recommendations more in keeping with the higher standards now demanded of animal experimentation. A variety of new techniques have been added throughout to expand the usefulness of the book, and more illustrations have been added to help in the execution of the various procedures. One of the greatest advances in the last twelve years is a greater appreciation for the well-being of experimental animals, and references to a more humane and refined approach have been made throughout this edition. This greater awareness of welfare issues demands that experimental animals be handled and used correctly and compassionately, with as little suffering as possible, and has led to a marked improvement in the attitude to proper training. This book is still the only source which provides a detailed and up-to-date compilation of illustrated experimental methods for work with the rat. It will continue to be an invaluable reference to specific information for laboratory workers and will help considerably in training new investigators in the proper and considerate use of this species. Key Features * All surgical techniques have been revised and updated * A new section on anesthesia and post-operative care has been included * Presents new techniques, particularly cannulation

Micro-surgery

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Publisher :
ISBN 13 :
Total Pages : 235 pages
Book Rating : 4.:/5 (645 download)

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Book Synopsis Micro-surgery by :

Download or read book Micro-surgery written by and published by . This book was released on 1976 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Liver Regeneration and Partial Liver Transplantation

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Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Liver Regeneration and Partial Liver Transplantation by : Aksel Foss

Download or read book Liver Regeneration and Partial Liver Transplantation written by Aksel Foss and published by . This book was released on 1992 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Experimental Organ Transplantation

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Publisher :
ISBN 13 : 9781626186088
Total Pages : 506 pages
Book Rating : 4.1/5 (86 download)

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Book Synopsis Experimental Organ Transplantation by : Huifang Chen

Download or read book Experimental Organ Transplantation written by Huifang Chen and published by . This book was released on 2014-05-14 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organ transplantation is one of the best therapeutic options for patients with end-stage organ failure. Experimental organ transplantation is an important link between basic science and clinical practice. Both editors, Dr. Chen and Dr. Qian, have been working in this area for more than 20 years. Experts from the United States, Canada, China, Japan, Italy, Span, Turkey, Switzerland, Hungary, and Brazil contributed 25 chapters in this book, and provided detailed descriptions of techniques for vascularized organ allografts in mice, rats, pigs, and nonhuman primates, as well as detailed descriptions of non-vascularized pancreatic islet and spleen allografts. Furthermore, they discussed new advances in transplantation immunology. This book provides numerous important references which were carefully selected by the authors to extend their visions and knowledge. The appropriate readers of this book include medical students, graduate students, residents, surgeons, physicians and immunologists interested in the transplantation area.

Hepatic Surgery

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Publisher : BoD – Books on Demand
ISBN 13 : 9535109650
Total Pages : 658 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Hepatic Surgery by : Hesham Abdeldayem

Download or read book Hepatic Surgery written by Hesham Abdeldayem and published by BoD – Books on Demand. This book was released on 2013-02-13 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: Longmire, called it a "hostile" organ because it welcomes malignant cells and sepsis so warmly, bleeds so copiously, and is often the ?rst organ to be injured in blunt abdominal trauma. To balance these negative factors, the liver has two great attributes: its ability to regenerate after massive loss of substance, and its ability, in many cases, to forgive insult. This book covers a wide spectrum of topics including, history of liver surgery, surgical anatomy of the liver, techniques of liver resection, benign and malignant liver tumors, portal hypertension, and liver trauma. Some important topics were covered in more than one chapter like liver trauma, portal hypertension and pediatric liver tumors.

Hepatocyte Transplantation

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Publisher : S. Karger AG (Switzerland)
ISBN 13 :
Total Pages : 372 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Hepatocyte Transplantation by : Michio Mito

Download or read book Hepatocyte Transplantation written by Michio Mito and published by S. Karger AG (Switzerland). This book was released on 1997 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly increasing frequency of organ transplantation is causing a severe shortage of donor organs. Hepatocyte transplantation has thus been studied to develop an alternative therapeutic method for patients with various liver diseases. In experimental studies using rodents, transplanted hepatocytes survive and function in ectopic sites for a long period of time. Recent advances in molecular biology and tissue engineering enable us to manipulate isolated hepatocytes before transplantation. Before clinical application of this new therapeutic method, there are many issues to be resolved such as determining an optimal location for transplantation, rapid proliferation of transplanted hepatocytes, transplantation in large animals, immunological reactions and long-term gene expression. In this book, authorities on hepatocyte transplantation from all over the world describe progress in this field and discuss the unsolved problems. For researchers and clinicians interested in the liver, this book will be the definitive resource on hepatocyte transplantation.

Experimental and Surgical Techniques in the Rat and Mouse

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Publisher : Academic Press
ISBN 13 : 9780128127889
Total Pages : pages
Book Rating : 4.1/5 (278 download)

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Book Synopsis Experimental and Surgical Techniques in the Rat and Mouse by : Flecknell

Download or read book Experimental and Surgical Techniques in the Rat and Mouse written by Flecknell and published by Academic Press. This book was released on 2018-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Innovative Medicine

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Publisher : Springer
ISBN 13 : 4431556516
Total Pages : 330 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Innovative Medicine by : Kazuwa Nakao

Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Experimental Transplantation Models in Small Animals

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Publisher : CRC Press
ISBN 13 : 9783718655236
Total Pages : 516 pages
Book Rating : 4.6/5 (552 download)

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Book Synopsis Experimental Transplantation Models in Small Animals by : B. R. Christie

Download or read book Experimental Transplantation Models in Small Animals written by B. R. Christie and published by CRC Press. This book was released on 1995-03-01 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to small animal use in transplantation research, for biomedical researchers. In most cases, the techniques were developed by the chapter authors. While some chapters are of general interest, other deal with specific procedures, mostly in rats and mice but with some rabbit work included. In acknowledgment of the ethical aspects of live animal experimentation, the detailed handling of the animals and the description of anesthesia and analgesia are central to many of the chapters. Thoroughly illustrated in bandw. Annotation copyright by Book News, Inc., Portland, OR

Use of Laboratory Animals in Biomedical and Behavioral Research

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Author :
Publisher : National Academies Press
ISBN 13 : 0309038391
Total Pages : 113 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Use of Laboratory Animals in Biomedical and Behavioral Research by : National Research Council

Download or read book Use of Laboratory Animals in Biomedical and Behavioral Research written by National Research Council and published by National Academies Press. This book was released on 1988-02-01 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.

Experimental Neurosurgery in Animal Models

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Author :
Publisher : Humana
ISBN 13 : 9781493937288
Total Pages : 0 pages
Book Rating : 4.9/5 (372 download)

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Book Synopsis Experimental Neurosurgery in Animal Models by : Miroslaw Janowski

Download or read book Experimental Neurosurgery in Animal Models written by Miroslaw Janowski and published by Humana. This book was released on 2016-06-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.