Radioimmunoassays For Insulin C Peptide And Proinsulin

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Radioimmunoassays for Insulin, C-Peptide and Proinsulin

Author : L. Heding
Publisher : Springer Science & Business Media
ISBN 13 : 9401170940
Total Pages : 85 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Radioimmunoassays for Insulin, C-Peptide and Proinsulin by : L. Heding

Download or read book Radioimmunoassays for Insulin, C-Peptide and Proinsulin written by L. Heding and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE DISCOVERY OF INSULIN, C-PEPTIDE AND PROINSULlN, SPECIES DIFFERENCES Crude insulin was extracted and isolated from dog pancreases removed 7-1 ° weeks after ligation of the pancreatic duct for the first time in 1921 by Banting and Best. Its lifesaving properties were subsequently documented in pancreatectomized dogs in 1922. Only about six months elapsed from its discovery until systematic collection of calf and ox pancreases and, later, porcine pancreases was established and the blood glucose lowering effect in diabetics using the crude extract from these glands proven. It was not until 1960, however, that the primary structure of all three species of insulin, lO7 human, porcine and bovine, was elucidated . It then became evident that the differences between bovine, porcine and human insulin amounted to at mosl 3 amino acids. These apparently small differences have a significant impact on the physico-chemical characteristics of the three insulins which again affect, e.g., the rate of absorption of insulin lO9 preparations from the subcutaneous tissue and their immunogenicity, i.e.

Radioimmunoassay of Canine Insulin, C-peptide and Glucagon : a Comparison and Evaluation of Commercial RIA Kits

Author : Steven Lloyd Stockham
Publisher :
ISBN 13 :
Total Pages : 170 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Radioimmunoassay of Canine Insulin, C-peptide and Glucagon : a Comparison and Evaluation of Commercial RIA Kits by : Steven Lloyd Stockham

Download or read book Radioimmunoassay of Canine Insulin, C-peptide and Glucagon : a Comparison and Evaluation of Commercial RIA Kits written by Steven Lloyd Stockham and published by . This book was released on 1980 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proinsulin, Insulin, C-peptide

Author : Shigeaki Baba
Publisher :
ISBN 13 :
Total Pages : 492 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Proinsulin, Insulin, C-peptide by : Shigeaki Baba

Download or read book Proinsulin, Insulin, C-peptide written by Shigeaki Baba and published by . This book was released on 1979 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Discovery of Insulin

Author : Michael Bliss
Publisher : University of Toronto Press
ISBN 13 : 1487516746
Total Pages : 320 pages
Book Rating : 4.4/5 (875 download)

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Book Synopsis The Discovery of Insulin by : Michael Bliss

Download or read book The Discovery of Insulin written by Michael Bliss and published by University of Toronto Press. This book was released on 2017-06-22 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.

Radioimmunoassay

Author : Rolf Luft
Publisher :
ISBN 13 : 9783135147017
Total Pages : 214 pages
Book Rating : 4.1/5 (47 download)

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Book Synopsis Radioimmunoassay by : Rolf Luft

Download or read book Radioimmunoassay written by Rolf Luft and published by . This book was released on 1974 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Proinsulin, Insulin, C-peptide

Author : Shigeaki Baba
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (959 download)

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Book Synopsis Proinsulin, Insulin, C-peptide by : Shigeaki Baba

Download or read book Proinsulin, Insulin, C-peptide written by Shigeaki Baba and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Methods of Hormone Radioimmunoassay

Author : Bernard Jaffe
Publisher : Elsevier
ISBN 13 : 032316126X
Total Pages : 1071 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Methods of Hormone Radioimmunoassay by : Bernard Jaffe

Download or read book Methods of Hormone Radioimmunoassay written by Bernard Jaffe and published by Elsevier. This book was released on 2012-12-02 with total page 1071 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods of Hormone Radioimmunoassay, Second Edition is a compilation of radioimmunoassay techniques for the quantification of hormones. Various kinds of hormones are considered, namely: intracellular messengers; hypothalamic and pineal hormones; pituitary hormones; thyroid and parathyroid hormones; renal hormones; hormones of the gastrointestinal tract; pancreatic hormones; steroid hormones; uterine and placental hormones; vasoactive peptide hormones; and growth factors. The corresponding method of radioimmunoassay for each hormone is described. This book is comprised of 49 chapters and begins with a discussion on the radioimmunoassay of cyclic adenosine-3',5-monophosphate (cAMP) and cyclic guanosine-3,5'-monophosphate (cGMP), together with problems related to measuring both compounds. The reader is then introduced to prostaglandins and prostaglandin metabolites, thyrotropin-releasing hormone, and gonadotropin-releasing hormone. Pituitaty gonadotropins, prolactin, and thyrotropin are also discussed. The remaining chapters deal with hormones of the gastrointestinal tract, pancreatic hormones, steroid hormones, and growth factors. This monograph is intended for both clinicians and investigators interested in methods of hormone radioimmunoassay.

Diabetes & C-Peptide

Author : Anders A.F. Sima
Publisher : Springer Science & Business Media
ISBN 13 : 1617793914
Total Pages : 176 pages
Book Rating : 4.6/5 (177 download)

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Book Synopsis Diabetes & C-Peptide by : Anders A.F. Sima

Download or read book Diabetes & C-Peptide written by Anders A.F. Sima and published by Springer Science & Business Media. This book was released on 2011-11-04 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide’s physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.

Diabetes Mellitus in Children

Author : Mark A. Sperling
Publisher :
ISBN 13 : 9781416027539
Total Pages : 0 pages
Book Rating : 4.0/5 (275 download)

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Book Synopsis Diabetes Mellitus in Children by : Mark A. Sperling

Download or read book Diabetes Mellitus in Children written by Mark A. Sperling and published by . This book was released on 2005 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Insulin Murders

Author : Vincent Marks
Publisher : CRC Press
ISBN 13 :
Total Pages : 204 pages
Book Rating : 4.7/5 (637 download)

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Book Synopsis Insulin Murders by : Vincent Marks

Download or read book Insulin Murders written by Vincent Marks and published by CRC Press. This book was released on 2007-04-26 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book ever to describe real life cases of murder, and purported murder, using insulin as a weapon. Covers cases from the USA, UK, Europe, Japan and New Zealand, including the well known Claus von Bulow case, the first criminal trial to be broadcast in its entirety on US TV (later the subject of a Hollywood movie, Reversal of Fortune). Written by Vincent Marks, coauthor of the critically acclaimed book Panic Nation: Exposing the Lies We're Told About Food and Health (John Blake Publishing) and a world authority on insulin, and Caroline Richmond, a medical journalist and writer, this gripping account is intended for doctors and laypeople alike, especially those with an interest in forensic medicine or true life crime.

Tietz Clinical Guide to Laboratory Tests - E-Book

Author : Alan H. B. Wu
Publisher : Elsevier Health Sciences
ISBN 13 : 1437719872
Total Pages : 1856 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Tietz Clinical Guide to Laboratory Tests - E-Book by : Alan H. B. Wu

Download or read book Tietz Clinical Guide to Laboratory Tests - E-Book written by Alan H. B. Wu and published by Elsevier Health Sciences. This book was released on 2006-06-08 with total page 1856 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition of Norbert Tietz's classic handbook presents information on common tests as well as rare and highly specialized tests and procedures - including a summary of the utility and merit of each test. Biological variables that may affect test results are discussed, and a focus is placed on reference ranges, diagnostic information, clinical interpretation of laboratory data, interferences, and specimen types. New and updated content has been added in all areas, with over 100 new tests added. Tests are divided into 8 main sections and arranged alphabetically. Each test includes necessary information such as test name (or disorder) and method, specimens and special requirements, reference ranges, chemical interferences and in vivo effects, kinetic values, diagnostic information, factors influencing drug disposition, and clinical comments and remarks. The most current and relevant tests are included; outdated tests have been eliminated. Test index (with extensive cross references) and disease index provide the reader with an easy way to find necessary information Four new sections in key areas (Preanalytical, Flow Cytometry, Pharmacogenomics, and Allergy) make this edition current and useful. New editor Alan Wu, who specializes in Clinical Chemistry and Toxicology, brings a wealth of experience and expertise to this edition. The Molecular Diagnostics section has been greatly expanded due to the increased prevalence of new molecular techniques being used in laboratories. References are now found after each test, rather than at the end of each section, for easier access.

Handbook of Immunoassay Technologies

Author : Sandeep K. Vashist
Publisher : Academic Press
ISBN 13 : 012811794X
Total Pages : 498 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Immunoassay Technologies by : Sandeep K. Vashist

Download or read book Handbook of Immunoassay Technologies written by Sandeep K. Vashist and published by Academic Press. This book was released on 2018-01-02 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text. Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules. Provides a valuable increase of understanding of cellular and biomedical functions Gives the most updated resource in the field of immunoassays, providing the comprehensive details of various types of immunoassays that need to be performed in healthcare, and in industrial, environmental and other biochemical settings Discusses all multifarious aspects of immunoassays Describes the immunoassay formats, along with their principle of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications Provides extensive knowledge and guided insights as detailed by experienced, renowned experts and key opinion makers in the field of immunoassays

Principles of Diabetes Mellitus

Author : Leonid Poretsky
Publisher : Springer Science & Business Media
ISBN 13 : 9781402071140
Total Pages : 788 pages
Book Rating : 4.0/5 (711 download)

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Book Synopsis Principles of Diabetes Mellitus by : Leonid Poretsky

Download or read book Principles of Diabetes Mellitus written by Leonid Poretsky and published by Springer Science & Business Media. This book was released on 2002 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes mellitus is a very common disease which affects approximately 150,000,000 worldwide. With its prevalence rising rapidly, diabetes continues to mystify and fascinate both practitioners and investigators by its elusive causes and multitude of This textbook is written for endocrinologists, specialists in other disciplines who treat diabetic patients, primary care physicians, housestaff and medical students. It covers, in a concise and clear manner, all aspects of the disease, from its pathogenesis on the molecular and cellular levels to its most modern therapy.

Joslin's Diabetes Mellitus

Author : Elliott Proctor Joslin
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781727969
Total Pages : 1244 pages
Book Rating : 4.7/5 (279 download)

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Book Synopsis Joslin's Diabetes Mellitus by : Elliott Proctor Joslin

Download or read book Joslin's Diabetes Mellitus written by Elliott Proctor Joslin and published by Lippincott Williams & Wilkins. This book was released on 2005 with total page 1244 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "bible" on diabetes mellitus is now in its Fourteenth Edition—thoroughly revised and updated by more than 80 noted experts from the Joslin Diabetes Center and other leading institutions worldwide. This edition includes a new eleven-chapter section on hormone action and the regulation of metabolism. The section on definition and pathogenesis now includes chapters on genetics, diabetes in Asia and Africa, and diabetes in U.S. minority groups. Other new chapters cover retinopathy, cardiovascular disease, wound healing, and treatment of women with diabetes. All of the Fourteenth Edition's figures have been completely updated.

Ghrelin

Author : Ezio Ghigo
Publisher : Springer Science & Business Media
ISBN 13 : 1402079710
Total Pages : 259 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Ghrelin by : Ezio Ghigo

Download or read book Ghrelin written by Ezio Ghigo and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ghrelin is a 28-amino acid acylated peptide predominatntly produced by the stomach. Highlights the impact and function of the hormone ghrelin and provides insight to neuroendocrinologies and researchers interested in its molecular and clinical relevance.

Immunotherapy of Type 1 Diabetes

Author : Domenico Andreani
Publisher : John Wiley & Sons
ISBN 13 :
Total Pages : 280 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Immunotherapy of Type 1 Diabetes by : Domenico Andreani

Download or read book Immunotherapy of Type 1 Diabetes written by Domenico Andreani and published by John Wiley & Sons. This book was released on 1989 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent national, European and international diabetes meetings have seen controversial discussions on the potential benefit and also on ethical aspects of immune intervention in patients with Type 1 diabetes or in persons with a high risk of developing the disease.

Endocrinology and Diabetes

Author : Ramzi Ajjan
Publisher : Springer
ISBN 13 : 1447127897
Total Pages : 222 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Endocrinology and Diabetes by : Ramzi Ajjan

Download or read book Endocrinology and Diabetes written by Ramzi Ajjan and published by Springer. This book was released on 2015-03-26 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides case studies accompanied by questions and commentaries for the specialist registrar in diabetes and endocrinology, to assist with problem-based learning during their training. The case studies range from the everyday to the rare and complicated, presenting a strong foundation for the specialist trainee to prepare them for their qualifying exams and, more importantly, for their future clinical consultations.