Quorum Sensing Vs Quorum Quenching A Battle With No End In Sight

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Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight

Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 8132219821
Total Pages : 391 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight by : Vipin Chandra Kalia

Download or read book Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight written by Vipin Chandra Kalia and published by Springer. This book was released on 2014-09-29 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS system through natural and synthetic compounds have been presented here. The biotechnological applications of QS inhibitors (QSIs) in diverse areas have also been dealt with. Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs. This book addresses a few questions. Will bacteria develop mechanisms to evade QSIs? Are we watching yet another defeat at the hands of bacteria? Or will we be acting intelligently and survive the onslaughts of this Never Ending battle?

Quorum Sensing and its Biotechnological Applications

Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 9811308489
Total Pages : 278 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Quorum Sensing and its Biotechnological Applications by : Vipin Chandra Kalia

Download or read book Quorum Sensing and its Biotechnological Applications written by Vipin Chandra Kalia and published by Springer. This book was released on 2018-08-11 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book delves into the biotechnological applications of Quorum sensing (QS)- a peculiar gene-regulatory process of some microorganisms. Quorum Sensing allows a large bacterial population to work together in a coordinated manner to carry out metabolic activities, which individual bacterium cannot. The different chapters describe how, associating bioremediation process with energy generation is an economical proposal, for reducing pollution and managing biowastes. The book discusses how QS can be exploited for biotechnological applications in generating bioproducts, bioenergy, bioremediation, biosensors, health and agricultural activities. It further highlights how QS is becoming an integral part of synthetic biology for genetic circuits for producing: (i) novel products, (ii) biosensors, (iii) bioactive molecules, etc. The book is divided into different sections for a clear understanding of the applicability of QS in, the Environment, Energy, Agriculture and Health sectors.

Biotechnological Applications of Quorum Sensing Inhibitors

Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 9811090262
Total Pages : 473 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Biotechnological Applications of Quorum Sensing Inhibitors by : Vipin Chandra Kalia

Download or read book Biotechnological Applications of Quorum Sensing Inhibitors written by Vipin Chandra Kalia and published by Springer. This book was released on 2018-05-30 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the practical applications of quorum sensing inhibitors for both human and plant health. Quorum sensing inhibitors that disrupt microbial biofilms can be employed to treat bacterial infections. The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors. Quorum sensing is the mechanism through which bacteria develop antibiotic resistance. Intended to provide a clearer understanding of the practical applications of quorum sensing inhibitors, the book details how the problem of antibiotic resistance can be countered through the intelligent application of quorum sensing inhibitors.

Microbial Factories

Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 8132225953
Total Pages : 355 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Microbial Factories by : Vipin Chandra Kalia

Download or read book Microbial Factories written by Vipin Chandra Kalia and published by Springer. This book was released on 2016-02-16 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the efforts made by distinguished scientific researchers world-wide to meet two key challenges: i) the limited reserves of polluting fossil fuels, and ii) the ever-increasing amounts of waste being generated. These case studies have brought to the foreground certain innovative biological solutions to real-life problems we now face on a global scale: environmental pollution and its role in deteriorating human health. The book also highlights major advances in microbial metabolisms, which can be used to produce bioenergy, biopolymers, bioactive molecules, enzymes, etc. Around the world, countries like China, Germany, France, Sweden and the US are now implementing major national programs for the production of biofuels. The book provides information on how to meet the chief technical challenges – identifying an industrially robust microbe and cheap raw material as feed. Of the various possibilities for generating bioenergy, the most attractive is the microbial production of biohydrogen, which has recently gained significant recognition worldwide, due to its high efficiency and eco-friendly nature. Further, the book highlights factors that can make these bioprocesses more economical, especially the cost of the feed. The anaerobic digestion (AD) process is more advantageous in comparison to aerobic processes for stabilizing biowastes and producing biofuels (hydrogen, biodiesel, 1,3-propanediol, methane, electricity), biopolymers (polyhydroxyalkanoates, cellulose, exopolysaccharides) and bioactive molecules (such as enzymes, volatile fatty acids, sugars, toxins, etc.) for biotechnological and medical applications. Information is provided on how the advent of molecular biological techniques can provide greater insights into novel microbial lineages. Bioinformatic tools and metagenomic techniques have extended the limits to which these biological processes can be exploited to improve human welfare. A new dimension to these scientific works has been added by the emergence of synthetic biology. The Big Question is: How can these Microbial Factories be improved through metabolic engineering and what cost targets need to be met?

Microbial Applications Vol.2

Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 3319526693
Total Pages : 336 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Microbial Applications Vol.2 by : Vipin Chandra Kalia

Download or read book Microbial Applications Vol.2 written by Vipin Chandra Kalia and published by Springer. This book was released on 2017-04-17 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume provides insights into multiple applications using microbes to promote productivity in agriculture, to produce biochemicals or to respond to challenges in biomedicine. It highlights the microbial production of nanocompounds with medical functionality alongside new anti-mycobacterial strategies, and introduces plant-growth-promoting Rhizobacteria as well as the correlation between biofilm formation and crop productivity. Further, the authors illustrate the green synthesis of biochemical compounds, such as hydroxamid acid or biosurfactants, using microbial and fungal enzymes. It inspires young researchers and experienced scientists in the field of microbiology to explore the combined use of green, white and red biotechnology for industrial purposes, which will be one of the central topics for future generations.

Microbial Applications Vol.1

Author : Vipin Chandra Kalia
Publisher : Springer
ISBN 13 : 3319526669
Total Pages : 331 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Microbial Applications Vol.1 by : Vipin Chandra Kalia

Download or read book Microbial Applications Vol.1 written by Vipin Chandra Kalia and published by Springer. This book was released on 2017-04-04 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This contributed volume sheds new light on waste management and the production of biofuels. The authors share insights into microbial applications to meet the challenges of environmental pollution and the ever- growing need for renewable energy. They also explain how healthy and balanced ecosystems can be created and maintained using strategies ranging from oil biodegration and detoxification of azo dyes to biofouling. In addition, the book illustrates how the metabolic abilities of microorganisms can be used in microbial fuel-cell technologies or for the production of biohydrogen. It inspires young researchers and experienced scientists in the field of microbiology to explore the application of green biotechnology for bioremediation and the production of energy, which will be one of the central topics for future generations.

Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors

Author :
Publisher : Elsevier
ISBN 13 : 0444640657
Total Pages : 320 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors by :

Download or read book Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors written by and published by Elsevier. This book was released on 2018-05-21 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors, Volume 81, describes the novelty of membrane bioreactors for the treatment of wastewater and the removal of specific contaminants that affect water quality or pose harm to humans. Topics of note in the updated release include Water Chemistry and Microbiology, Quorum Sensing as Bacterial Communication Language, the Effects of Quorum Sensing, Quorum Quenching, Membrane Bioreactors for Wastewater Treatment, Removal of Specific Contaminants, Microextraction Techniques, and the Determination of Quorum Sensing Chemicals. The contents of this updated volume will be appealing to a wide range of researchers as the authors of most chapters are experts in their respective fields with numerous published studies. Gives an overview of quorum sensing as a communication language for bacteria and quorum quenching mediated approaches to mitigate or eliminate the effects of quorum sensing Presents various sensitive determination methods where a variety of microextraction strategies is used for preconcentration of analyte(s)

Quorum Sensing

Author : Giuseppina Tommonaro
Publisher : Academic Press
ISBN 13 : 0128149051
Total Pages : 310 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Quorum Sensing by : Giuseppina Tommonaro

Download or read book Quorum Sensing written by Giuseppina Tommonaro and published by Academic Press. This book was released on 2019-04-15 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists. Describes Quorum Sensing (QS) mechanisms from their molecular basis, to their clinical applications Spans several fields in relation to QS, including microbiology, chemistry, biochemistry and ecology Considers QS as an approach to the discovery of new antibiotics Looks at QS as a means to understand the microbial world and towards use of bacteria and their products in biotechnological applications Summarizes key results on QS mechanisms' molecular basis and fields of application

Implication of Quorum Sensing System in Biofilm Formation and Virulence

Author : Pallaval Veera Bramhachari
Publisher : Springer
ISBN 13 : 9811324298
Total Pages : 381 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Implication of Quorum Sensing System in Biofilm Formation and Virulence by : Pallaval Veera Bramhachari

Download or read book Implication of Quorum Sensing System in Biofilm Formation and Virulence written by Pallaval Veera Bramhachari and published by Springer. This book was released on 2019-01-28 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the importance and significance of Quorum sensing (QS), it’s critical roles in regulating diverse cellular functions in microbes, including bioluminescence, virulence, pathogenesis, gene expression, biofilm formation and antibiotic resistance. Microbes can coordinate population behavior with small molecules called autoinducers (AHL) which serves as a signal of cellular population density, triggering new patterns of gene expression for mounting virulence and pathogenesis. Therefore, these microbes have the competence to coordinate and regulate explicit sets of genes by sensing and communicating amongst themselves utilizing variety of signals. This book descry emphasizes on how bacteria can coordinate an activity and synchronize their response to external signals and regulate gene expression. The chapters of the book provide the recent advancements on various functional aspects of QS systems in different gram positive and gram negative organisms. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with quorum sensing signal molecules viz. virulence, pathogenesis, antibiotic synthesis, biosurfactants production, persister cells, cell signaling and biofilms, intra and inter-species communications, host-pathogen interactions, social interactions & swarming migration in biofilms.

Quorum Quenching for Biocontrol of Plant Diseases

Author : Shaohua Chen
Publisher : Scientific Research Publishing, Inc. USA
ISBN 13 : 1649974620
Total Pages : 301 pages
Book Rating : 4.6/5 (499 download)

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Book Synopsis Quorum Quenching for Biocontrol of Plant Diseases by : Shaohua Chen

Download or read book Quorum Quenching for Biocontrol of Plant Diseases written by Shaohua Chen and published by Scientific Research Publishing, Inc. USA. This book was released on 2022-08-29 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathogenic microorganisms can cause crop diseases in various plants, leading to a decline in the quality and yield of crops. To more sustainably mitigate the impact of crop diseases on plant health and productivity, there is a need for more safe and eco-friendly strategies as compared to chemical prevention.

Quorum Network (Sensing/Quenching) in Multidrug-Resistant Pathogens

Author : Rodolfo Garcia-Conteras
Publisher : Frontiers Media SA
ISBN 13 : 2889458822
Total Pages : 237 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Quorum Network (Sensing/Quenching) in Multidrug-Resistant Pathogens by : Rodolfo Garcia-Conteras

Download or read book Quorum Network (Sensing/Quenching) in Multidrug-Resistant Pathogens written by Rodolfo Garcia-Conteras and published by Frontiers Media SA. This book was released on 2019-06-28 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The findings of the contributed studies from this Research Topic reflect important aspects (hot topics) of Quorum network (Sensing/Quenching) in multidrug-resistant pathogens, which including: (i) novel mechanisms of QS and detection techniques, (ii) QS/QQ in clinical multidrug resistant strains, (iii) the relationship between QS/QQ as well as multidrug resistance, and (iv) the application of new QQ therapies.

Alternatives to Antibiotics

Author : Tilak Saha
Publisher : Springer Nature
ISBN 13 : 9811918546
Total Pages : 574 pages
Book Rating : 4.8/5 (119 download)

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Book Synopsis Alternatives to Antibiotics by : Tilak Saha

Download or read book Alternatives to Antibiotics written by Tilak Saha and published by Springer Nature. This book was released on 2022-08-08 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses prospective alternative approaches to fight bacterial infections to minimize the indiscriminate use of conventional antibiotics. It offers the current knowledge on research and development of alternative antibacterial agents such as probiotics, nanobiotics etc. while it also discusses newly emerging trends such as phage therapy, antibody therapy etc. The book highlights on the phytochemicals with potent antibacterial activities as alternatives to conventional antibiotics. Chemical modification to develop next generation antibiotics with enhanced efficacy has also been included. Such modifications are reported to overcome the inherent resistance of the parent antibiotics. Phage therapy and targeted antibodies are considered as potential alternative approaches to treat bacterial ailments and represent areas of cutting-edge research and have therefore been discussed with sufficient care. Mainly, the book highlights various approaches other than conventional antibiotics in treating bacterial infections. The scientific advancements in these areas will strengthen the ‘One Health’ approach benefiting human beings, animals and environment as well. This book is a comprehensive resource to cater researchers, biological scientists, herbalists and clinical practitioners with up-to-date information on antibacterials other than antibiotics.

Drug Discovery and Design Using Natural Products

Author : Jorddy Neves Cruz
Publisher : Springer Nature
ISBN 13 : 303135205X
Total Pages : 541 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Drug Discovery and Design Using Natural Products by : Jorddy Neves Cruz

Download or read book Drug Discovery and Design Using Natural Products written by Jorddy Neves Cruz and published by Springer Nature. This book was released on 2023-08-28 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, natural products have great relevance for the development of new drugs. Natural molecules, in addition to directly providing new compounds with different therapeutic functions have provided scaffolds and a great diversity of structures that serve as inspiration for the design and discovery of new drugs. The great structural complexity and the significant number of natural compounds that can be obtained and their advantages also present some historical problems that need to be overcome. Issues such as difficulty in isolation, difficulty in synthesizing compounds found in nature in the laboratory, screening to evaluate the biological properties of these compounds, and structural optimization to enhance the pharmacological properties of biomolecules; are some of the main difficulties encountered in research with natural products and in the design/discovery of new medicines. Therefore, this book addresses the great scientific advances that provide practical solutions to using natural products to develop new drugs. We address topics related to the genesis of research projects that use natural products to design new drugs. We address the discovery of new species, initial processes for identification and extraction of compounds, isolation and identification of these structures, techniques, and advances in vitro and in vivo methods that support the discovery of new natural drugs, synthesis of new compounds from natural molecules, in silico optimization processes of potentially promising compounds.

Recent Advancements in Microbial Diversity

Author : Surajit de Mandal
Publisher : Academic Press
ISBN 13 : 0128212667
Total Pages : 624 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Recent Advancements in Microbial Diversity by : Surajit de Mandal

Download or read book Recent Advancements in Microbial Diversity written by Surajit de Mandal and published by Academic Press. This book was released on 2020-06-02 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microorganisms are a major part of the Earth’s biological diversity. Although a lot of research has been done on microbial diversity, most of it is fragmented. This book creates the need for a unified text to be published, full of information about microbial diversity from highly reputed and impactful sources. Recent Advancements in Microbial Diversity brings a comprehensive understanding of the recent advances in microbial diversity research focused on different bodily systems, such as the gut. Recent Advancements in Microbial Diversity also discusses how the application of advanced sequencing technologies is used to reveal previously unseen microbial diversity and show off its function. Gives insight into microbial diversity in different bodily systems Explains novel approaches to studying microbial diversity Highlights the use of omics to analyze the microbial community and its functional attributes Discusses the techniques used to examine microbial diversity, including their applications and respective strengths and weaknesses

Promising Antimicrobials from Natural Products

Author : Mahendra Rai
Publisher : Springer Nature
ISBN 13 : 3030835049
Total Pages : 454 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Promising Antimicrobials from Natural Products by : Mahendra Rai

Download or read book Promising Antimicrobials from Natural Products written by Mahendra Rai and published by Springer Nature. This book was released on 2022-02-03 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given novel infectious diseases such as COVID-19 and antibiotic resistance new antimicrobial discovery is an important research area. Considering that nature is a vast source of bioactive molecules with antimicrobial activity, the main aim of this book is to present a comprehensive outlook of current research in the field of natural antimicrobials. It discusses the antimicrobial activity of medicinal plants, beehives, and mushrooms with a global coverage of antimicrobial agents from rich forests of Brazil (Amazon), North-Eastern forests of Peru, Argentina, Colombia, India, Bangladesh, Nepal, Middle East, Turkey, Croatia, Greece, Germany and Russia. The book covers the results of the in vitro screening of antimicrobial activities of extracts and isolated compounds from natural origins. It is divided into three sections: i) Section I, includes natural antimicrobials from plants; ii) Section II incorporates antimicrobial agents/secondary metabolites from plants, and (iii) Section III focuses on antimicrobials from mushrooms, beehive and delivery systems for different types of antimicrobials. Promising Antimicrobials From Natural Products is immensely useful for post graduate students, researchers in plant science, microbiology, biotechnology, pharmacology, pharma companies and those who are interested in herbal, eco-friendly, cost-effective and sustainable antimicrobials

Plant-Microbe Interactions in Agro-Ecological Perspectives

Author : Dhananjaya Pratap Singh
Publisher : Springer
ISBN 13 : 981105813X
Total Pages : 657 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Plant-Microbe Interactions in Agro-Ecological Perspectives by : Dhananjaya Pratap Singh

Download or read book Plant-Microbe Interactions in Agro-Ecological Perspectives written by Dhananjaya Pratap Singh and published by Springer. This book was released on 2017-09-27 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: This books presents an updated compilation on fundamental interaction mechanisms of microbial communities with the plant roots and rhizosphere (belowground) and leaves and aerial parts (aboveground). Plant rhizopshere recruits its own microbial composition that survive there and help plants grow and develop better under biotic and abiotic conditions. Similar is the case with the beneficial microorganisms which are applied as inoculants with characteristic functions. The mechanism of plant-microbe interactions is interesting phenomenon in biological perspectives with numerous implications in the fields. The First volume focuses on the basic and fundamental mechanisms that have been worked out by the scientific communities taking into account different plant-microbe systems. This includes methods that decipher mechanisms at cellular, physiological, biochemical and molecular levels and the functions that are the final outcome of any beneficial or non-beneficial interactions in crop plants and microbes. Recent advances in this research area is covered in different book chapters that reflect the impact of microbial interactions on soil and plant health, dynamics of rhizosphere microbial communities, interaction mechanisms of microbes with multiple functional attributes, microbiome of contrasting crop production systems (organic vs conventional), mechanisms behind symbiotic and pathogenic interactions, endophytic (bacterial and fungal) interaction and benefits, rhizoplane and endosphere associations, signalling cascades and determinants in rhizosphere, quorum sensing in bacteria and impact on interaction, mycorrhizal interaction mechanisms, induced disease resistance and plant immunization, interaction mechanisms that suppress disease and belowground microbial crosstalk with plant rhizosphere. Methods based on multiphasic and multi-omics approaches were discussed in detail by the authors. Content-wise, the book offers an advanced account on various aspects of plant-microbe interactions and valuable implications in agro-ecological perspectives.

Nanozymology

Author : Xiyun Yan
Publisher : Springer Nature
ISBN 13 : 9811514909
Total Pages : 564 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Nanozymology by : Xiyun Yan

Download or read book Nanozymology written by Xiyun Yan and published by Springer Nature. This book was released on 2020-01-30 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces the new concept of “nanozyme”, which refers to nanomaterials with intrinsic enzymatic activity, rather than nanomaterials with biological enzymes incorporated on the surface. The book presents the cutting-edge advances in nanozyme, with emphasis on state-of-the-art applications in many important fields, such as in the biomedical fields and for environmental protection. The nanozyme is a totally new type of artificial enzyme and exhibits huge advantages over natural enzymes, including greater stability, low cost, versatility, simplicity, and suitability for industry. It is of interest to university researchers, R&D engineers, as well as graduate students in nanoscience and technology, and biology wishing to learn the core principles, methods, and the corresponding applications of “nanozyme”.