Quinones and Quinone Enzymes, Part B

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Publisher : Elsevier
ISBN 13 : 0080497209
Total Pages : 611 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Quinones and Quinone Enzymes, Part B by :

Download or read book Quinones and Quinone Enzymes, Part B written by and published by Elsevier. This book was released on 2004-03-08 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers more clinical aspects of quinines, such as anticancer properties, as well as their role in nutrition and in age-related diseases. Mitochondrial Ubiquinone and Reductases Anticancer Quinones and Quinone Oxido-Reductases Quininone Reductases: Chemoprevention, Nutrition Quinones and Age-Related Diseases

Quinones and Quinone Enzymes, Part A

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Author :
Publisher : Elsevier
ISBN 13 : 0080497160
Total Pages : 461 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Quinones and Quinone Enzymes, Part A by : Helmut Sies

Download or read book Quinones and Quinone Enzymes, Part A written by Helmut Sies and published by Elsevier. This book was released on 2004-05-01 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quinones are members of a class of aromatic compounds with two oxygen atoms bonded to the ring as carbonyl groups. This volume covers the role of quinines enzymes in cellular signalling and modulation of gene expression. *Coenzyme Q: Detection and Quinone Reductases *Plasma Membrane Quinone Reductases *Quinones, Cellular Signaling, and Modulation of Gene Expression

Chromatin and Chromatin Remodeling Enzymes

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Publisher : Elsevier
ISBN 13 : 0080497144
Total Pages : 458 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Chromatin and Chromatin Remodeling Enzymes by : Carl Wu

Download or read book Chromatin and Chromatin Remodeling Enzymes written by Carl Wu and published by Elsevier. This book was released on 2004-03-07 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodelling enzymes play an important role in gene transcription.

Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates

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Author :
Publisher : Academic Press
ISBN 13 : 0080923364
Total Pages : 644 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates by :

Download or read book Complex Enzymes in Microbial Natural Product Biosynthesis, Part B: Polyketides, Aminocoumarins and Carbohydrates written by and published by Academic Press. This book was released on 2009-04-11 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject will showcase the most important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. In both classes, variation in sub-unit structure, number and chemical modification leads to an almost infinite variety of final structures, accounting for the huge importance of the compounds in nature and medicine. Gathers tried and tested methods and techniques from top players in the field Provides an extremely useful reference for the experienced research scientist Covers biosynthesis of Polyketides, Tarpenoids, Aminocoumarins and Crabohydrates

Globins and Other Nitric Oxide-Reactive Proteins, Part B

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Publisher : Academic Press
ISBN 13 : 0080877923
Total Pages : 710 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Globins and Other Nitric Oxide-Reactive Proteins, Part B by : Robert K. Poole

Download or read book Globins and Other Nitric Oxide-Reactive Proteins, Part B written by Robert K. Poole and published by Academic Press. This book was released on 2011-09-02 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect — full-text online of volumes 1 onwards. For more information about the Elsevier Book Series on ScienceDirect Program, please visit: http://www.info.sciencedirect.com/bookseries/ This volume is the second of two planned volumes on the topic of globin and other nitric oxide-reactive proteins.

Chemokines

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Publisher : Academic Press
ISBN 13 : 9780080956961
Total Pages : 350 pages
Book Rating : 4.9/5 (569 download)

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Book Synopsis Chemokines by :

Download or read book Chemokines written by and published by Academic Press. This book was released on 2009-05-26 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The understanding of chemokines, the proteins that control the migration of cells, and their receptors, is critical to the study of causes and therapies for a wide range of human diseases and infections, including certain types of cancer, inflammatory diseases, HIV, and malaria. This volume, focusing on chemokine structure and function, as well as signaling, and its companion volume (Methods in Enzymology volume 461, focusing on chemokines as potential targets for disease intervention) provide a comprehensive overview and time-tested protocols in this field, making it an essential reference for researchers in the area. Along with its companion volume, provides a comprehensive overview of chemokine methods, specifically as related to potential disease therapy Gathers tried, tested, and trusted methods and techniques from top players in chemokine research Provides an essential reference for researchers in the field

Chromatin and Chromatin Remodeling Enzymes, Part A

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Author :
Publisher : Elsevier
ISBN 13 : 0080497136
Total Pages : 579 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Chromatin and Chromatin Remodeling Enzymes, Part A by : Carl Wu

Download or read book Chromatin and Chromatin Remodeling Enzymes, Part A written by Carl Wu and published by Elsevier. This book was released on 2004-02-20 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the Chromatin remodellng enzymes play an important role in gene transcription. *Histone Bioinformatics *Biochemistry of histones, nucleosomes and chromatin *Molecular cytology of chromatin functions

Chromatin and Chromatin Remodeling Enzymes

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Publisher : Elsevier
ISBN 13 : 0080497152
Total Pages : 546 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Chromatin and Chromatin Remodeling Enzymes by : Carl Wu

Download or read book Chromatin and Chromatin Remodeling Enzymes written by Carl Wu and published by Elsevier. This book was released on 2004-04-07 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA in the nucleus of plant and animal cells is stored in the form of chromatin. Chromatin and the chromatin remodelling enzymes play an important role in gene transcription. Genetic assays of chromatin modification and remodeling Histone modifying enzymes ATP-dependent chromatin remodeling enzymes

Cilia, Part B

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Publisher : Academic Press
ISBN 13 : 0123984858
Total Pages : 497 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Cilia, Part B by :

Download or read book Cilia, Part B written by and published by Academic Press. This book was released on 2013-03-16 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers cilia Contains chapters on such topics as methods for studying ciliary polarity in Xenopus, analysis of signaling pathways in mammalian spermatozoa, and biochemical and physiological analysis of axonemal dyneins

DNA Repair

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Publisher : Elsevier
ISBN 13 : 9780080464671
Total Pages : 616 pages
Book Rating : 4.4/5 (646 download)

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Book Synopsis DNA Repair by :

Download or read book DNA Repair written by and published by Elsevier. This book was released on 2011-09-21 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume emphasizes the intracellular consequences of DNA damage, describing procedures for analysis of checkpoint responses, DNA repair in vivo, replication fork encounter of DNA damage, as well as biological methods for analysis of mutation production and chromosome rearrangements. It also describes molecular methods for analysis of a number of genome maintenance activities including DNA ligases, helicases, and single-strand binding proteins. *Part B of a 2-part series *Addresses DNA maintenance enzymes *Discusses damage signaling *Presents In vivo analysis of DNA repair *Covers mutation and chromosome rearrangements

Mitochondrial Function, Part B

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Publisher : Academic Press
ISBN 13 : 9780080923505
Total Pages : 450 pages
Book Rating : 4.9/5 (235 download)

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Book Synopsis Mitochondrial Function, Part B by :

Download or read book Mitochondrial Function, Part B written by and published by Academic Press. This book was released on 2009-05-05 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this second of two new volumes covering mitochondria, methods developed to assess the number and function of nuclear-encoded proteins in the mitochondrion are presented. Chapters focus on the regulation of mitochondrial function and mitochondrial diseases, with a section emphasizing the mitochondrial defects associated with type 2 diabetes. The critically acclaimed laboratory standard for 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. With more than 450 volumes published, each volume presents material that is relevant in today's labs -- truly an essential publication for researchers in all fields of life sciences. New methods focusing on the examination of normal and abnormal mitochondrial function are presented in an easy-to-follow format by the researchers who developed them Along with a companion volume covering topics including mitochondrial electron transport chain complexes and reactive oxygen species, provides a comprehensive overview of modern techniques in the study of mitochondrial malfunction Provides a "one-stop shop" for tried and tested essential techniques, eliminating the need to wade through untested or unreliable methods

Liposomes

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Publisher : Elsevier
ISBN 13 : 008049711X
Total Pages : 479 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Liposomes by : Nejat Duzgunes

Download or read book Liposomes written by Nejat Duzgunes and published by Elsevier. This book was released on 2003-11-19 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liposomes are cellular structures made up of lipid molecules. Important as a cellular model in the study of basic biology, liposomes are also used in clinical applications such as drug delivery and virus studies. Liposomes in Biochemistry Liposomes in Molecular Cell Biology Liposomes in Molecular Virology

Programmed Cell Death

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Publisher : Elsevier
ISBN 13 : 9780080888132
Total Pages : 504 pages
Book Rating : 4.8/5 (881 download)

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Book Synopsis Programmed Cell Death by : Roya Khosravi-Far

Download or read book Programmed Cell Death written by Roya Khosravi-Far and published by Elsevier. This book was released on 2008-07-29 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the major goals of researchers in the field of apoptosis is to identify targets for novel therapies in cancer, AIDS, and Alzheimer’s disease. Understanding the molecular mechanisms of the various components of the apoptotic pathways is the first step to reaching this goal. The 2002 Nobel Prize in Physiology or Medicine was awarded to Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E. Sulston (UK) "for their discoveries concerning genetic regulation of organ development and programmed cell death." Cell death is a fundamental aspect of embryonic development, normal cellular turnover and maintenance of homeostasis (maintaining a stable, constant environment) on the one hand, and aging and disease on the other. This volume addresses the significant advances with the techniques that are being used to analyze cell death. * This volume provides the necessary, trusted methods to carry out this research on these latest therapeutic techniques. Once researchers understand the molecular mechanisms of the apoptotic pathways, they can begin to develop new therapies. * Presents key methods on studying tumors and how these cancer cells evade cell death. * Eliminates searching through many different sources to avoid pitfalls so the same mistakes are not made over and over.

Two-Component Signaling Systems, Part B

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Publisher : Academic Press
ISBN 13 : 0080549462
Total Pages : 646 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Two-Component Signaling Systems, Part B by :

Download or read book Two-Component Signaling Systems, Part B written by and published by Academic Press. This book was released on 2007-07-03 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multicellular organisms must be able to adapt to cellular events to accommodate prevailing conditions. Sensory-response circuits operate by making use of a phosphorylation control mechanism known as the "two-component system." Sections in Two-Component Signaling Systems, Part B include: Structural Approaches Reconstitution of Heterogeneous Systems Intracellular Methods and Assays Genome-Wide Analyses of Two-Component Systems Presents detailed protocols Includes troubleshooting tips

Angiogenesis: In Vivo Systems

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Publisher : Academic Press
ISBN 13 : 9780080921662
Total Pages : 464 pages
Book Rating : 4.9/5 (216 download)

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Book Synopsis Angiogenesis: In Vivo Systems by :

Download or read book Angiogenesis: In Vivo Systems written by and published by Academic Press. This book was released on 2009-02-12 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding how angiogenesis "works" and how to control it will have massive implications on the management, treatments, and ultimately the prevention of many common (and not so common) diseases. Angiogenesis is the growth of new blood vessels and is an important natural process in the body. A healthy body maintains a perfect balance of angiogenesis modulators. In many serious disease states, however, the body loses control over angiogenesis. Diseases that are angiogenesis-dependent result when blood vessels either grow excessively or insufficiently. * Tried-and-tested techniques written by researchers that developed them, used them, and brought them to fruition * Provides the "builder's manual" for essential techniques--a one-stop shop that eliminates needless searching among untested techniques * Includes step-by-step methods for understanding the cell and molecular basis of wound healing, vascular integrin signaling, mechanical signaling in blood vessels, and vascular proteomics

Small GTPases in Disease

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Publisher : Academic Press
ISBN 13 : 9780080570075
Total Pages : 616 pages
Book Rating : 4.5/5 (7 download)

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Book Synopsis Small GTPases in Disease by :

Download or read book Small GTPases in Disease written by and published by Academic Press. This book was released on 2008-04-01 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt: The critically acclaimed laboratory standard for more than 40 years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences. Methods in Enzymology is now available online at ScienceDirect — full-text online of volume 1 onward.

Autophagy in Mammalian Systems, Part B

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Publisher : Academic Press
ISBN 13 : 0080923259
Total Pages : 571 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Autophagy in Mammalian Systems, Part B by : Daniel Klionsky

Download or read book Autophagy in Mammalian Systems, Part B written by Daniel Klionsky and published by Academic Press. This book was released on 2009-03-05 with total page 571 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the companion volume to Daniel Klionsky’s Autophagy: Lower Eukaryotes, which features the basic methods in autophagy covering yeasts and alternative fungi (aspergillus, podospora, magnaporthe). Klionsky is one of the leading authorities in the field. He is the editor-in-chief of Autophagy. The November 2007 issue of Nature Reviews highlighted his article, “Autophagy: From phenomenology to molecular understanding in less than a decade. He is currently editing guidelines for the field, with 230 contributing authors, that will publish in Autophagy. Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal “house cleaning in the cell is called autophagy – literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 (autophagy-related gene 1) in yeast. (To date, 30 additional yeast genes have been identified.) These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth.