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Author : Marcus Hugh Galea
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)
Download or read book Quantitative Pathology and Prognosis in Breast Cancer written by Marcus Hugh Galea and published by . This book was released on 1992 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jan P. A. Baak
Publisher : Berlin ; New York : Springer-Verlag
ISBN 13 :
Total Pages : 646 pages
Book Rating : 4.3/5 (91 download)
Download or read book Manual of Quantitative Pathology in Cancer Diagnosis and Prognosis written by Jan P. A. Baak and published by Berlin ; New York : Springer-Verlag. This book was released on 1991 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Paul J. Diest
Publisher : Elsevier Publishing Company
ISBN 13 :
Total Pages : 232 pages
Book Rating : 4.3/5 (91 download)
Download or read book Quantitative Cyto- and Histoprognosis in Breast Cancer written by Paul J. Diest and published by Elsevier Publishing Company. This book was released on 1992 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an updated edition of the summa cum laude PhD thesis Quantative Cyto- and Histoprognosis in Breast Cancer. An integrated approach using morphometry, stereology, flow cytometry, digital image processing, syntactic structure analysis and artificial intelligence by P.J. van Diest M.D., Ph.D. It provides an extensive overview of the current status of prognostic factors in breast cancer. A series of articles demonstrates recent progress in the development and implementation of quantitative prognostic factors, derived from cytological and histological material. Many experts have contributed in the process of preparing this comprehensive edition
Author : Paulus J. van Diest
Publisher :
ISBN 13 : 9789062569496
Total Pages : 299 pages
Book Rating : 4.5/5 (694 download)
Download or read book Quantitative cyto- and histoprognosis in breast cancer written by Paulus J. van Diest and published by . This book was released on 1990 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : David J Dabbs
Publisher : Elsevier Health Sciences
ISBN 13 : 0323462367
Total Pages : 848 pages
Book Rating : 4.3/5 (234 download)
Download or read book Breast Pathology E-Book written by David J Dabbs and published by Elsevier Health Sciences. This book was released on 2016-11-04 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now completely updated with the latest classifications of breast pathology and molecular diagnosis, David J. Dabbs’ Breast Pathology, 2nd Edition, remains your go-to source for integrated, comprehensive coverage of this fast-changing field. Written by internationally acclaimed pathologists, this definitive reference incorporates genomic and molecular information, clinical presentation, gross and microscopic pathologic findings, radiologic and laboratory diagnosis, immunohistochemistry, and theranostics – providing complete, authoritative information for pathology trainees, practitioners, and oncologists. Approximately 2,000 full-color pathological images clearly depict clinical, radiological, molecular, immunohistochemical, and theranostic aspects of disease. Quick reference points at the beginning of each chapter conveniently list all relevant diagnostic, theranostic, and genomic data for fast retrieval. Immunohistochemistry for each entity is mapped according to diagnostic, theranostic, and genomic applications with specific regards to disease entities in each chapter. Breast specimen handling is discussed in detail to ensure proper sampling and processing for optimal molecular and immunohistochemistry resulting. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. All chapters have been updated with the latest breast pathology classifications and the most recent information on molecular diagnosis. New chapter on next generation DNA sequencing and management of clinically advanced breast cancer.
Author : David J Dabbs
Publisher : Elsevier Health Sciences
ISBN 13 : 0323795234
Total Pages : 1008 pages
Book Rating : 4.3/5 (237 download)
Download or read book Breast Pathology, E-Book written by David J Dabbs and published by Elsevier Health Sciences. This book was released on 2023-05-19 with total page 1008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written with useful practicality in mind, Breast Pathology, 3rd Edition, provides surgical pathologists with authoritative guidance on the selection and best use of proper diagnostic techniques when reporting on breast specimens. Dr. David J. Dabbs and a team of internationally acclaimed pathologists incorporate genomic and molecular information, gross and microscopic findings, radiologic and laboratory diagnosis, theranostics, and immunohistochemistry to cover every aspect of benign and malignant lesions of the breast, helping you minimize diagnostic variation and error in the sign-out room. - Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer. - Incorporates the latest classifications of breast pathology and molecular diagnosis. - Organizes each topical chapter around relevant genomic and molecular information, clinical presentation, gross and microscopic pathologic findings and diagnostic and molecular immunohistochemistry. - Maps immunohistochemistry for each entity according to diagnostic, theranostic, and genomic applications, with specific regard to disease entities in each chapter. - Discusses breast specimen handling in detail to assure proper sampling and processing for optimal molecular and immunohistochemistry resulting. - Supplies a convenient quick reference at the beginning of each chapter that includes all relevant diagnostic, theranostic, and genomic data for fast retrieval. - Features approximately 2,000 full-color pathological images that clearly depict clinical, radiological, molecular, immunohistochemical, and theranostic aspects of disease. - Includes biomarker guideline updates throughout. - Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays.
Author : Ajay Nagesh Basavanhally
Publisher :
ISBN 13 :
Total Pages : 123 pages
Book Rating : 4.:/5 (872 download)
Download or read book Quantitative Histomorphometry of Digital Pathology as a Companion Diagnostic written by Ajay Nagesh Basavanhally and published by . This book was released on 2014 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work involves the creation of an image-based companion diagnostic framework that employs quantitative features extracted from whole-slide, H & E stained digital pathology (DP) images to distinguish patients based on disease outcome, with a clinical application aimed at distinguishing estrogen receptor-positive (ER+) breast cancer (BCa) patients with good and poor outcomes. Quantitative histomorphometry (QH) -- the conversion of a digitized histopathology slide into a series of quantitative measurements of tumor morphology -- is a rapidly growing field aimed at introducing advanced image analytics into the histopathological workflow. The thrust towards personalized medicine has led to the development of companion diagnostic tools that measure gene expression, yielding quantitative outcome predictions for improved disease stratification and customized therapies, e.g. Oncotype DX (Genomic Health, Inc.) for ER+ BCa. Yet, tumor morphology is often correlated with genomic assays, suggesting that genotypic variations in biologically distinct classes of tumors lead to distinct patterns of tumor cell morphology and tissue architecture in histopathology. The application of this work to ER+ BCa is highly relevant to current clinical needs. Current treatment guidelines recommend that the majority of women with ER+ BCa receive chemotherapy in addition to hormonal therapy; yet, approximately half will not benefit from chemotherapy while still enduring its harmful side effects. Hence, there is a clear need for the development of automated prognostic tools to identify women with poorer outcomes who will likely benefit from chemotherapy. The primary novel contributions of this work are (1) a color standardization system for improving the consistency in appearance of tissue structures across images, (2) the identification of tissue structures and corresponding QH signatures with prognostic value in ER+ BCa, (3) a multi-field-of-view framework for robust integration of prognostic information across whole-slide DP images, and (4) a method for predicting classifier performance for a large data cohort based on the availability of limited training data. This work will pave the way for the development of novel companion diagnostic systems capable of producing quantitative and reproducible image-based risk scores. These risk scores will play a vital role in decision support by helping clinicians predict patient outcome and prescribing appropriate therapies.
Author : Stuart J. Schnitt
Publisher : Elsevier Health Sciences
ISBN 13 : 1455739421
Total Pages : 276 pages
Book Rating : 4.4/5 (557 download)
Download or read book Breast Pathology: Diagnosis and Insights, An Issue of Surgical Pathology Clinics written by Stuart J. Schnitt and published by Elsevier Health Sciences. This book was released on 2012-10-02 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinically accessible information for pathologists on histology, molecular pathology, differential diagnosis, and clinical overview is presented. Common and rare entities are covered with an abundance of images to highight key features.Topics for pathologists covering the fast moving field of breast pathology include: Less common variants and mimics of DCIS; Invasive lobular carcinoma and its variants; Important inflammatory and reactive lesions; Small glandular proliferations; Vascular lesions of the breast; Combined epithelial-myoepithelial lesion; Immunhistochemical pitfalls in the diagnosis of breast lesions; Pathology considerations in patients treated with neoadjuvant chemotherapy; Molecular classification of breast cancer: Jorge Reis-Filho; Prognostic factors for patients with breast cancer: Traditional and New
Author : Sunil Badve
Publisher : Springer
ISBN 13 : 3319417614
Total Pages : 427 pages
Book Rating : 4.3/5 (194 download)
Download or read book Molecular Pathology of Breast Cancer written by Sunil Badve and published by Springer. This book was released on 2016-11-26 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complex landscape of breast cancer requires distinct strategies for the management of various molecular subtypes of this disease. Rapid advances in the field of molecular biology have been bewildering for those involved in its study and management. “Molecular Pathology of Breast Cancer” aims to close this knowledge gap by discussing comprehensively the evolution, biological basis and clinical applications with a focus on the “what, when, and how” of the most significant molecular markers known to date. These markers are evaluated in the context of genomic, transcriptomic and proteomic profiles, which is integral to the practice of precision medicine. The application of next generation sequencing (NGS) has provided new insights in the regulation of genomic and transcriptomic structure and function. Alterations in DNA such as mutations and single nucleotide polymorphisms (SNPs) have been correlated with outcomes and provide for novel therapeutic approaches. These NGS analyses have also revealed the extensive contributions of epigenetic mechanisms such as histone modifications, non-coding RNA and alternative splicing. All of these changes together contribute to alterations in proteome. Newer assays that allow greater stability and analytical consistency are emerging. These alterations in tumor profiles can be also now detected by imaging techniques. The heterogeneity of both tumor and tumor microenvironment, an inevitable reality, is discussed in detail with particular focus on cancer stem cells and immune signaling. A chapter is dedicated to the emerging technology of “liquid biopsy”, which opens a novel approach for “continuous” monitoring of cancer that might be superior to conventional diagnostics, “Molecular Pathology of Breast Cancer” provides a quick and easy, not to mention essential, tour for clinicians, pathologists and scientists who are seeking to understand the integration of molecular biology into the diagnosis, prognosis and management of breast cancer.
Author : Yan Peng
Publisher : Springer
ISBN 13 : 3030165183
Total Pages : 269 pages
Book Rating : 4.0/5 (31 download)
Download or read book Practical Breast Pathology written by Yan Peng and published by Springer. This book was released on 2019-07-18 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive volume reviews current topics and controversies in diagnostic breast pathology, and addresses frequently encountered diagnostic problems using a question and answer format and case presentations. Emphasis is placed on the diagnostic approach as it relates to morphology, clinical and radiographic correlation, differential diagnosis, and ancillary testing including immunohistochemical and molecular analyses. Answers are provided and serve as a practical, evidence-based, and problem solving guide to diagnostic issues having significant impacts on clinical management. Common but diagnostically challenging entities such as papillary lesions and fibroepithelial lesions are discussed in detail, as well as special types of breast cancer including solid papillary carcinoma, lobular lesions and its variants. Uncommon breast lesions such as mesenchymal, lymphoid, and metastatic lesions are also covered. Chapters discuss genetic alterations and molecular abnormalities in breast cancer, and commonly encountered interpretation dilemmas on immunohistochemistry in breast cancer and metastatic cancer to the breast with a focus on prognostic and predictive tumor biomarkers.
Author : Kristen A. Atkins
Publisher : Elsevier Health Sciences
ISBN 13 : 1455733407
Total Pages : 351 pages
Book Rating : 4.4/5 (557 download)
Download or read book Practical Breast Pathology: A Diagnostic Approach E-Book written by Kristen A. Atkins and published by Elsevier Health Sciences. This book was released on 2012-10-29 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Apply a systematic pattern recognition method to achieve more accurate diagnoses with Practical Breast Pathology: A Diagnostic Approach. Using a practical, pattern-based organization, this volume in the Pattern Recognition series guides you efficiently and confidently through the evaluation of even the most challenging neoplastic and non-neoplastic specimens in breast pathology, and also highlights patterns crucial to radiologic diagnosis. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Compare specimens to commonly seen patterns, categorize them accordingly, and turn directly to in-depth diagnostic guidance using the unique, pattern-based Visual Index at the beginning of the book. Assess key pathologic and clinical aspects of both neoplastic and non-neoplastic conditions with over 530 high-quality, full-color images that help you evaluate and interpret biopsy samples. Apply the latest techniques and advances in the field, including optimal processing of breast specimens for early detection of breast cancer, the latest molecular diagnosis in breast pathology, and the use of radiology in optimizing detection of breast lesions. Progress logically from the histological pattern, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Find the information you’re looking for quickly and easily with patterns color-coded to specific entities in the table of context and text and key points summarized in tables, charts, and graphs. Review all the information essential for completing a sign-out report: clinical findings, pathologic findings, diagnosis, treatment, and prognosis. View key diagnostic features associated with less common conditions in a visual encyclopedia of unusual patterns at the end of the book.
Author : Susan C. Lester
Publisher : Elsevier Health Sciences
ISBN 13 : 0323758967
Total Pages : 779 pages
Book Rating : 4.3/5 (237 download)
Download or read book Diagnostic Pathology: Breast, E-Book written by Susan C. Lester and published by Elsevier Health Sciences. This book was released on 2021-02-19 with total page 779 pages. Available in PDF, EPUB and Kindle. Book excerpt: This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of breast pathology, it incorporates the most recent clinical, pathological, radiological, staging, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Breast is a one-stop reference for accurate, complete surgical pathology evaluation—ideal as a day-to-day reference or as a reliable training resource. - Includes a wide range of new information on breast pathology, including material specific to core needle biopsies, to help you identify, diagnose, and manage disease - Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays - Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer - Features new chapters covering gene expression profiling; immunotherapy; the differential diagnosis for common histologic patterns; solid papillary carcinoma; acinic cell carcinoma; and intraoperative consultations, including a video showing how to process specimens with radioactive seeds - Offers expert guidance on evaluation of postneoadjuvant resection specimens, sentinel lymph nodes, and extent of disease and multifocality - Contains thousands of extensively annotated images, including gross pathology photographs, histopathology photomicrographs with a wide range of immunohistochemical stains, fluorescent in situ hybridization, and full-color illustrations - Features a templated, highly formatted design; concise, bulleted text; diagnostic pearls; key facts in each chapter; and an extensive index for easy reference - Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices
Author : Susan Victoria Makkink-Nombrado
Publisher :
ISBN 13 : 9789090077727
Total Pages : 192 pages
Book Rating : 4.0/5 (777 download)
Download or read book Quantitative Pathological, Cell- and Molecular Biological Markers in Breast Cancer written by Susan Victoria Makkink-Nombrado and published by . This book was released on 1995 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Adnan Aydiner
Publisher : Springer
ISBN 13 : 3319228439
Total Pages : 305 pages
Book Rating : 4.3/5 (192 download)
Download or read book Breast Disease written by Adnan Aydiner and published by Springer. This book was released on 2015-11-02 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first of two volumes provides and in-depth account of breast disease characteristics, imaging and diagnosis. Covering from breast anatomy and tumor biology to benign and malignant lesions this is an indispensable companion for breast specialists, medical oncologists, radiologists and pathologists. The book is organised in themed parts exploring topics such as epidemiology, risk factors, genetic biomarkers, pathological evaluation of tumors and biopsy techniques. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into pathological and epidemiological aspects of breast disease. Covering both theoretical and practical aspects of breast cancer this is a highly informative and carefully presented book which will appeal to an international audience of breast cancer practitioners.
Author : Susan C. Lester, MD, PhD
Publisher : Elsevier Health Sciences
ISBN 13 : 0323377122
Total Pages : 710 pages
Book Rating : 4.3/5 (233 download)
Download or read book Diagnostic Pathology: Breast written by Susan C. Lester, MD, PhD and published by Elsevier Health Sciences. This book was released on 2016-02-10 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Breast, second edition, is a visually stunning, easy-to-use reference covering all aspects of breast pathology. Outstanding images, including gross and microscopic pathology, a wide range of supportive immunohistochemistry, and detailed medical illustrations with numerous examples of morphologic findings, make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Thoroughly updated content throughout, including coverage of new technologies and molecular approaches that are quickly moving out of the laboratory into clinical diagnosis and therapeutic decision making New to this edition: Tips on how to biopsy and send the best block for breast cancer predictive factor testing, updated prognostic assays, updated national guidelines (including HER2 testing) with photos, neoadjuvant treatment, new drugs for HER2-positive cancers, and pattern-based differential diagnosis chapters and guidance on the most helpful IHC antibodies For each anatomical site, you will find CAP cancer staging and specimen handling protocols, plus detailed immunohistochemistry panels to accompany the images High-quality, carefully annotated color images provide clinically and diagnostically important information Fully integrated, searchable, and linked content between differential diagnostic categories is perfectly suited for residents, while new images and outstanding graphics make this text ideal for both residents and practitioners Time-saving reference features include bulleted text, a variety of data tables, key facts in each chapter, annotated images, and an extensive index Expert Consult eBook version included, which allows you to search all of the text, figures, and references from the book on a variety of devices
Author : Paul Peter Rosen
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781723794
Total Pages : 1028 pages
Book Rating : 4.7/5 (237 download)
Download or read book Rosen's Breast Pathology written by Paul Peter Rosen and published by Lippincott Williams & Wilkins. This book was released on 2001 with total page 1028 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Second Edition of this gold-standard text and reference provides a comprehensive description of breast pathology in a clinical context, with emphasis on morphological descriptions of breast cancer in all its many variations. Updates include new information on sentinel lymph node biopsy and increased coverage of needle core biopsy. Dr. Rosen also discusses a new staging system and advances in prognostic markers. More than 2,700 illustrations--including more than 2,000 in full color--provide the true-to-life perspective essential to accurate diagnosis, prognosis, and management.
Author : Susan C. Lester
Publisher : Elsevier Health Sciences
ISBN 13 : 0323442986
Total Pages : 710 pages
Book Rating : 4.3/5 (234 download)
Download or read book Diagnostic Pathology: Breast E-Book written by Susan C. Lester and published by Elsevier Health Sciences. This book was released on 2016-04-20 with total page 710 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the highly regarded Diagnostic Pathology series, Diagnostic Pathology: Breast, second edition, is a visually stunning, easy-to-use reference covering all aspects of breast pathology. Outstanding images, including gross and microscopic pathology, a wide range of supportive immunohistochemistry, and detailed medical illustrations with numerous examples of morphologic findings, make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Thoroughly updated content throughout, including coverage of new technologies and molecular approaches that are quickly moving out of the laboratory into clinical diagnosis and therapeutic decision making New to this edition: Tips on how to biopsy and send the best block for breast cancer predictive factor testing, updated prognostic assays, updated national guidelines (including HER2 testing) with photos, neoadjuvant treatment, new drugs for HER2-positive cancers, and pattern-based differential diagnosis chapters and guidance on the most helpful IHC antibodies For each anatomical site, you will find CAP cancer staging and specimen handling protocols, plus detailed immunohistochemistry panels to accompany the images High-quality, carefully annotated color images provide clinically and diagnostically important information Fully integrated, searchable, and linked content between differential diagnostic categories is perfectly suited for residents, while new images and outstanding graphics make this text ideal for both residents and practitioners Time-saving reference features include bulleted text, a variety of data tables, key facts in each chapter, annotated images, and an extensive index Expert Consult eBook version included, which allows you to search all of the text, figures, and references from the book on a variety of devices
