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Proteoglycans In Stem Cells
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Book Synopsis Proteoglycans in Stem Cells by : Martin Götte
Download or read book Proteoglycans in Stem Cells written by Martin Götte and published by Springer Nature. This book was released on 2021-06-07 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a state-of-the-art compendium on the role of proteoglycans and glycosaminoglycans during development and in cancer. It also suggests directions for novel therapeutic and biotechnological applications in stem cell biology. Proteoglycans and glycosaminoglycans, as part of the extracellular matrix, are multifunctional modulators of growth factor, cytokine, integrin and morphogen signaling, which determine both self-renewal, senescence and/or differentiation of stem cells during development. Since proteoglycans modulate cell adhesion and migration they are important organizers of the extracellular matrix within the proper stem cell niche. A malfunctioning of proteoglycans and glycosaminoglycans contributes to the cancer stem cell phenotype, which is linked to therapeutic resistance and recurrence in malignant disease. This book is essential reading for anyone interested in the extracellular matrix and its role in development. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.
Book Synopsis Proteoglycans: Advances in Research and Application: 2011 Edition by :
Download or read book Proteoglycans: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteoglycans: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Proteoglycans in a compact format. The editors have built Proteoglycans: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Proteoglycans in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Proteoglycans: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Stem Cells and Extracellular Matrices by : Lakshmi Kiran Chelluri
Download or read book Stem Cells and Extracellular Matrices written by Lakshmi Kiran Chelluri and published by Morgan & Claypool Publishers. This book was released on 2012 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells have great potential in regenerative medicine and tissue injury. Regulation of stem cell homeostasis in a 3D microenvironment is controlled by the niche components that influence stem cell fate, regulation, and function. It is therefore necessary to understand the mechanisms of cell-cell interaction, molecular cross talk between stem cells and their extracellular matrix (ECM) environment. The adhesion molecules play a pivotal role in establishing the cell-cell contact and subsequent integration with the ECM. This understanding is the basis for establishing design criteria for biomimetic. The integrated approach by biologists, material science engineers, biomedical engineers, and clinicians is the key in the development of tissue engineered constructs for effective translation to clinics. Table of Contents: Abbreviations / Introduction to Stem Cell Biology and Niche Components / ECM-Structure and Organization / ECM Control, Regulation on Stem Cell Fate and Function / ECM and Stem Cell Cultures / Acknowledgments / Bibliography / Author Biography / Titles of Related Interest
Book Synopsis Proteoglycans—Advances in Research and Application: 2013 Edition by :
Download or read book Proteoglycans—Advances in Research and Application: 2013 Edition written by and published by ScholarlyEditions. This book was released on 2013-06-21 with total page 47 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proteoglycans—Advances in Research and Application: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about ZZZAdditional Research in a compact format. The editors have built Proteoglycans—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Proteoglycans—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Biology of Proteoglycans by : Thomas N. Wight
Download or read book Biology of Proteoglycans written by Thomas N. Wight and published by Elsevier. This book was released on 2013-09-11 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology of Proteoglycans provides a representative, but by no means inclusive, sample of current research on the role of proteoglycans in the cell biology of the extracellular matrix. The book is organized into four areas: methodological developments; proteoglycan metabolism; proteoglycans in cartilage; and proteoglycans in "soft" tissues. It begins with discussions of current methodological developments which have had enormous impact on understanding the complexity of proteoglycan structure. These include the use of monoclonal antibodies to probe the structure of the protein and carbohydrate portions of proteoglycans; and studies on the genes that code for the proteoglycan protein cores and associated proteins. This is followed by separate chapters on various aspects of proteoglycan metabolism, including the synthetic pathway used by cells to synthesize proteoglycans containing heparin and heparan sulfate; the molecular organization of different proteoglycans in cartilage; the role of proteoglycans and associated proteins in the calcification process in growth plate; and the emerging field of proteoglycans in "soft" or noncartilagenous tissue.
Book Synopsis Glycosaminoglycans and Proteoglycans by : 978-3-03842-836-7
Download or read book Glycosaminoglycans and Proteoglycans written by 978-3-03842-836-7 and published by MDPI. This book was released on 2018-07-04 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Glycosaminoglycans and Proteoglycans" that was published in Pharmaceuticals
Book Synopsis Proteoglycans as Mediators of Cell Behavior by : Larisa M. Haupt
Download or read book Proteoglycans as Mediators of Cell Behavior written by Larisa M. Haupt and published by Frontiers Media SA. This book was released on 2021-11-16 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Functions of the Proteoglycans by : David Evered
Download or read book Functions of the Proteoglycans written by David Evered and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a comprehensive review of current proteoglycan research, which is providing fresh insights into many major chronic diseases. The proteoglycans are a family of macromolecules which contain one or more glycosaminoglycan chains covalently bound to a core protein. Proteoglycans are a major component of the extracellular matrix of connective tissues and help to determine its volume, resiliency, and organization. They are an important medium through which nutrients, hormones, and other solutes are transported to cells, and they play a significant role in cell-cell interactions. Disturbances in proteoglycans occur in rheumatic and connective tissue disorders, degenerative bone disease, vascular disease, renal disease, and malignant disorders.
Book Synopsis Role of Proteoglycans on Bone Marrow Endothelium in Stem Cell Homing by : Tanja Netelenbos
Download or read book Role of Proteoglycans on Bone Marrow Endothelium in Stem Cell Homing written by Tanja Netelenbos and published by . This book was released on 2002 with total page 157 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Glycans in Diseases and Therapeutics by : Mauro S.G. Pavão
Download or read book Glycans in Diseases and Therapeutics written by Mauro S.G. Pavão and published by Springer Science & Business Media. This book was released on 2011-04-19 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Initially believed to be inactive molecules, glycans are now considered essential for life, both under normal and pathological conditions. This volume of the series “Biology of Extracellular Matrix” reviews the most recent findings on the role of glycans in the development of diseases and the possible therapeutic use of this class of molecules. It shows how the interaction of glycans with growth factors, growth factor binding proteins, extracellular proteases, protease inhibitors, chemokines, morphogens, and adhesive proteins regulates inflammation, infection, cancer, atherosclerosis, thrombosis and embryonic stem cell biology. Furthermore, an extensive survey about the structure and pharmacological effects of unique marine glycosaminoglycans is discussed as well as the possibility of using these glycans as therapeutic agents.
Download or read book Proteoglycans written by Renato V. Iozzo and published by CRC Press. This book was released on 2000-04-05 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive, up-to-date review of the structure, biology, and molecular interactions of proteoglycans, consolidating into a single source research using molecular, cellular, and animal systems. Of particular note is an in-depth look at the role of heparan sulfate in modulating growth factors and morphogens.
Book Synopsis The Extracellular Matrix: an Overview by : Robert Mecham
Download or read book The Extracellular Matrix: an Overview written by Robert Mecham and published by Springer Science & Business Media. This book was released on 2011-02-16 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
Book Synopsis Glycoconjugates by : Howard J. Allen
Download or read book Glycoconjugates written by Howard J. Allen and published by CRC Press. This book was released on 1992-04-15 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycoconjugates Composition: Structure, and Function provides an excellent overview of the composition, biosynthesis, function and structure of the carbohydrate chains of glycoconjugates from higher organisms. It is recommended as a core reference text, providing excellent coverage of the glycoconjugate field.
Download or read book Proteoglycans written by Pierre Jollès and published by Birkhauser. This book was released on 1994 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Heparan Sulfate Proteoglycans—Advances in Research and Application: 2012 Edition by :
Download or read book Heparan Sulfate Proteoglycans—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heparan Sulfate Proteoglycans—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Heparan Sulfate Proteoglycans in a compact format. The editors have built Heparan Sulfate Proteoglycans—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Heparan Sulfate Proteoglycans in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Heparan Sulfate Proteoglycans—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Book Synopsis Chemistry and Biology of Heparin and Heparan Sulfate by : Hari G. Garg
Download or read book Chemistry and Biology of Heparin and Heparan Sulfate written by Hari G. Garg and published by Elsevier. This book was released on 2011-10-10 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chemistry, biochemistry and pharmacology of heparin and heparan sulfate have been and continue to be a major scientific undertaking - heparin and its derivative remain important drugs in clinical practice. Chemistry and Biology of Heparin and Heparan Sulfate provides readers with an insight into the chemistry, biology and clinical applications of heparin and heparan sulfate and examines their function in various physiological and pathological conditions. Providing a wealth of useful information, no other tome covers the diversity of topics in the field. Students, doctors, chemists, biochemists, and research scientists will find this book an invaluable source for updating their current knowledge of developments in this area. Comprehensively reviews all aspects of heparin and heparan sulfate research Uniquely describes the chemistry, biology and clinical application of heparins and heparan sulfates in one work Provides an invaluable source of knowledge of current developments for chemists, biochemists, medical doctors, researchers, students and practitioners
