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Progranulin Assisted Autophagy And Notch Signaling A 2 Step Repair Mechanism That Resolves Neuropathic Pain After Peripheral Nerve Injury
Download Progranulin Assisted Autophagy And Notch Signaling A 2 Step Repair Mechanism That Resolves Neuropathic Pain After Peripheral Nerve Injury full books in PDF, epub, and Kindle. Read online Progranulin Assisted Autophagy And Notch Signaling A 2 Step Repair Mechanism That Resolves Neuropathic Pain After Peripheral Nerve Injury ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Neurologic Differential Diagnosis by : Alan B. Ettinger
Download or read book Neurologic Differential Diagnosis written by Alan B. Ettinger and published by Cambridge University Press. This book was released on 2014-04-17 with total page 693 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unique case-based guide to generating diagnostic possibilities based on the patients' symptoms. Invaluable for psychiatrists and neurologists.
Book Synopsis The First Outstanding 50 Years of “Università Politecnica delle Marche” by : Sauro Longhi
Download or read book The First Outstanding 50 Years of “Università Politecnica delle Marche” written by Sauro Longhi and published by Springer Nature. This book was released on 2020-01-03 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes significant multidisciplinary research findings at the Università Politecnica delle Marche and the expected future advances. It addresses some of the most dramatic challenges posed by today’s fast-growing, global society and the changes it has caused, while also discussing solutions to improve the wellbeing of human beings. The book covers the main research achievements made in the social sciences and humanities, and includes chapters that focus on understanding mechanisms that are relevant to all aspects of economic and social interactions among individuals. In line with Giorgio Fuà’s contribution, the interdisciplinary research being pursued at the Faculty of Economics of Università Politecnica delle Marche is aimed at interpreting the process of economic development in all of its facets, both at the national and local level, with a particular focus on profit and non-profit organizations. Various disciplines are covered, from economics to sociology, history, statistics, mathematics, law, accounting, finance and management.
Book Synopsis Lysosomes by : Frederick R. Maxfield
Download or read book Lysosomes written by Frederick R. Maxfield and published by John Wiley & Sons. This book was released on 2016-06-22 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discussing recent findings, up-to-date research, and novel strategies, the book integrates perspectives from pharmacology, toxicology, and biochemistry to illustrate the potential of lysosomes in drug discovery and development. • Explores basic principles and properties of lysosomes that allow them to act as regulators of cell metabolism, therapeutic targets, and sites for activation of drug conjugates • Discusses the role of lysosomes in metabolism, drug targeting, apoptosis, cancer, aging, inflammation, autophagy, metabolism, toxicity, and membrane repair • Introduces new pathways in therapeutic development and new mechanisms in drug development
Book Synopsis Progressive Myoclonus Epilepsies by : Berge A. Minassian
Download or read book Progressive Myoclonus Epilepsies written by Berge A. Minassian and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progressive myoclonus epilepsies are a group of rare genetic diseases. The onset generally occurs around puberty in otherwise healthy children. They all involve myoclonus and epilepsy but then differ depending on the different symptoms that are related. The outlook of these diseases is nearly always unfavourable and treatment only focuses on symptoms. Much planning will be needed to improve the quality of life for these children who will gradually become over time more and more severely disabled. Among these diseases, the most notable is Unverricht-Lundborg disease and Lafora disease, among others. However, the genetic mechanism of these diseases is simple and has been perfectly identified over time thanks to advancements in scientific discoveries. Hope lies in gene therapy, which in the near future will most likely be able to optimise treatment and even cure these children. This book addresses the situation by relying on clinicians descriptions, studies led by biologists on genetic variations and mutations and the work carried out daily by numerous scientists researching into treatment. By retracing the history of these diseases, from discovery and identification of mutated genes to the review of syndromes they encompass, this book marks the path we have travelled but also the distance we have yet to go.
Book Synopsis Harrison's Neurology in Clinical Medicine, 3E by : Stephen Hauser
Download or read book Harrison's Neurology in Clinical Medicine, 3E written by Stephen Hauser and published by McGraw Hill Professional. This book was released on 2013-04-08 with total page 897 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurology – as only Harrison’s can cover it Featuring a superb compilation of chapters related to neurology that appear in Harrison’s Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. Features Current, complete coverage of clinically important topics in neurology, including Clinical Manifestations of Neurologic Diseases, Diseases of the Nervous System, Chronic Fatigue Syndrome, Psychiatric Disorders, and Alcoholism and Drug Dependency NEW CHAPTERS discuss the pathogenesis and treatment and syncope; dizziness and vertigo; peripheral neuropathy; neuropsychiatric problems among war veterans; and advances in deciphering the pathogenesis of common psychiatric disorders Integration of pathophysiology with clinical management 118 high-yield questions and answers drawn from Harrison’s Principles of Internal Medicine Self-Assessment and Board Review, 18e Content updates and new developments since the publication of Harrison’s Principles of Internal Medicine, 18e 58 chapters written by physicians who are recognized experts in the field of clinical neurology Helpful appendix of laboratory values of clinical importance
Book Synopsis Alzheimer: 100 Years and Beyond by : Mathias Jucker
Download or read book Alzheimer: 100 Years and Beyond written by Mathias Jucker and published by Springer Science & Business Media. This book was released on 2006-11-22 with total page 541 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen. The celebratory event "Alzheimer 100 Years and Beyond" was organized through the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen. This volume, a collection of articles by the invited speakers and of a few other prominent researchers, is published as a record of those events.
Download or read book Neurogenetics, Part II written by and published by Elsevier. This book was released on 2018-01-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. - Contains comprehensive coverage of neurogenetics - Details the latest science and its impact on our understanding of neurological, psychiatric disorders - Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Book Synopsis Dento/Oro/Craniofacial Anomalies and Genetics by : Agnes Bloch-Zupan
Download or read book Dento/Oro/Craniofacial Anomalies and Genetics written by Agnes Bloch-Zupan and published by Elsevier. This book was released on 2012-03-21 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dental defects may be the physical expression of genetic defects, and so they can often be seen in a variety of syndromes associated with malformations of organs. However, dental defects are often not recognized, identified, nor characterised despite representing a possible diagnostic sign for an undiagnosed condition. This book addresses this gap by providing an understanding of dental genetics and its developmental biology counterpart. With approximately seventy well-illustrated examples, the authors present the clinical oro-facial manifestations accompanying various syndromes, providing the necessary knowledge for diagnostic purposes, as well as giving insight into recent development for each specific condition. The clarity and format of this book make it an ideal support guide both in the clinic and while conducting research. Comprehensive examination of dento/oro/craniofacial anomalies Well-illustrated examples Presented in a compact, easy to use format
Download or read book Progranulin written by Andrew Bateman and published by Humana Press. This book was released on 2018-06-28 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores experimental strategies to study progranulin as a regulatory protein in biological and disease processes. The chapters in this book are divided into four parts: Part One is an introduction to the topic; Part Two looks at analytical and in vitro methods to study progranulin biology; Part Three discusses the role of progranulin in cancer; and Part Four describes the process of using animal models to study progranulin in health and disease. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Progranulin: Methods and Protocols is a valuable resource for experienced researchers who want to expand their studies of this field, and newcomers who want to begin including progranulin into their work.
Book Synopsis Medical and Health Genomics by : Dhavendra Kumar
Download or read book Medical and Health Genomics written by Dhavendra Kumar and published by Academic Press. This book was released on 2016-06-04 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. - Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management - Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study - Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management - Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems
Book Synopsis Rehabilitation After Traumatic Brain Injury by : Blessen C. Eapen
Download or read book Rehabilitation After Traumatic Brain Injury written by Blessen C. Eapen and published by Elsevier Health Sciences. This book was released on 2018-01-24 with total page 295 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering the full spectrum of rehabilitation after traumatic brain injury, this practical reference by Drs. Blessen C. Eapen and David X. Cifu presents best practices and considerations for numerous patient populations and their unique needs. In an easy-to-read, concise format, it covers the key information you need to guide your treatment plans and help patients relearn critical life skills and regain their independence. - Covers neuroimaging, neurosurgical and critical care management, management of associated complications after TBI, pharmacotherapy, pain management, sports concussion, assistive technologies, and preparing patients for community reintegration. - Discusses special populations, including pediatric, geriatric, and military and veteran patients. - Consolidates today's available information and guidance in this challenging and diverse area into one convenient resource.
Book Synopsis Analysis of Complex Disease Association Studies by : Eleftheria Zeggini
Download or read book Analysis of Complex Disease Association Studies written by Eleftheria Zeggini and published by Academic Press. This book was released on 2010-11-17 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that is designed to identify genetic associations with observable traits (such as blood pressure or weight), or the presence or absence of a disease or condition. Whole genome information, when combined with clinical and other phenotype data, offers the potential for increased understanding of basic biological processes affecting human health, improvement in the prediction of disease and patient care, and ultimately the realization of the promise of personalized medicine. In addition, rapid advances in understanding the patterns of human genetic variation and maturing high-throughput, cost-effective methods for genotyping are providing powerful research tools for identifying genetic variants that contribute to health and disease. This burgeoning science merges the principles of statistics and genetics studies to make sense of the vast amounts of information available with the mapping of genomes. In order to make the most of the information available, statistical tools must be tailored and translated for the analytical issues which are original to large-scale association studies. Analysis of Complex Disease Association Studies will provide researchers with advanced biological knowledge who are entering the field of genome-wide association studies with the groundwork to apply statistical analysis tools appropriately and effectively. With the use of consistent examples throughout the work, chapters will provide readers with best practice for getting started (design), analyzing, and interpreting data according to their research interests. Frequently used tests will be highlighted and a critical analysis of the advantages and disadvantage complimented by case studies for each will provide readers with the information they need to make the right choice for their research. Additional tools including links to analysis tools, tutorials, and references will be available electronically to ensure the latest information is available. - Easy access to key information including advantages and disadvantage of tests for particular applications, identification of databases, languages and their capabilities, data management risks, frequently used tests - Extensive list of references including links to tutorial websites - Case studies and Tips and Tricks
Book Synopsis Neurosensory Disorders in Mild Traumatic Brain Injury by : Michael E. Hoffer
Download or read book Neurosensory Disorders in Mild Traumatic Brain Injury written by Michael E. Hoffer and published by Academic Press. This book was released on 2018-11-24 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mild traumatic Brain Injury (mTBI or Concussion) is an increasingly common public health issue in sports, military environments, and life in today's active world. Despite a great deal of study and public attention to this disorder, knowledge about optimal diagnostic, prognostic, and treatment information remains lacking. Neurosensory symptoms have been shown to be the most frequent complications of mTBI in both the acute and chronic setting. Neurosensory Disorders in Mild Traumatic Brain Injury brings together both the basic science work as well as the clinical work in mTBI into one volume to provide a comprehensive examination of the neurosensory issues associated with this disorder. Coverage includes chapters on defining mild Traumatic Brain Injury, neurosensory consequences, neurosensory disorders in clinical practice, and diagnosis and treatment for neurosensory disorders in mTBI. This book is written for clinicians, researchers, residents and students in neurology and neuroscience. - Provides a comprehensive examination of the neurosensory issues associated with mild Traumatic Brain Injury and concussion - Brings together both the basic science work and the clinical work in mTBI into a single volume - Helps clinicians understand the best diagnosis and treatment paths and puts current research into perspective for researchers
Book Synopsis Reverse Shoulder Arthroplasty by : David M. Dines
Download or read book Reverse Shoulder Arthroplasty written by David M. Dines and published by Thieme. This book was released on 2017-09-27 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This masterful book from top experts provides clinical insights on reverse shoulder arthroplasty gleaned from hands-on refinement of shoulder replacement techniques. Years of significant biomechanical and clinical research yielded invaluable knowledge that led to important improvements in functional outcome and implant durability. Among these refinements were stronger polyethylene derivatives, better ingrowth technology, and improved connection devices. As the durability and longevity of implant technology increased, younger active patients became suitable candidates for this procedure. In fact, RSA has played a pivotal role in making shoulder arthroplasty the fastest growing implant technology. In the first two sections, the authors take the reader through the history and evolution of RSA, followed by step-by-step surgical techniques for specific injuries and conditions. The next three sections discuss past and recent outcomes, complications, and rehabilitation. The last section covers special considerations including patient specific instrumentation, convertible humeral and glenoid components, and the future potential of stemless humeral technology. Key Features The latest trends in patient-specific components, guide systems, and instrument design The use of RSA for rotator cuff repair, shoulder arthritis, and acute and complex fractures In-depth discussion of techniques to improve deltoid function, avoid impingement, and increase implant longevity Clinical pearls on how to recognize and handle complications that occur: instability, infection, scapular notching, component loosening, glenoid and humeral bone loss, and RSA failure High quality videos and 300 superb illustrations further delineate techniques This book is a practical resource that enables learning complex procedures, putting them into practice, and handling complications should they arise. It is an essential tool for all orthopaedic surgeons who treat shoulder conditions.
Book Synopsis New Therapeutics for Traumatic Brain Injury by : Kim Heidenreich
Download or read book New Therapeutics for Traumatic Brain Injury written by Kim Heidenreich and published by Academic Press. This book was released on 2016-09-27 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury. - Comprehensive overview of basic approaches and translational development of new therapies for TBI - Edited by a prominent TBI researcher that includes contributions by leading global researchers in the field - Presents a great resource for researchers and practitioners to learn more about the many evolving preclinical studies and clinical trials currently underway, and the challenges of bringing translational studies in TBI to the clinic
Book Synopsis Biomarkers in Alzheimer's Disease by : Tapan Khan
Download or read book Biomarkers in Alzheimer's Disease written by Tapan Khan and published by Academic Press. This book was released on 2016-08-02 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Alzheimer's Disease provides a comprehensive overview of all modalities of Alzheimer's disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer's disease and technological advancement of biomarkers techniques. The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer's disease, and for differential diagnosis of Alzheimer's disease with other non-Alzheimer's dementia. - Presents a comprehensive overview detailing all modalities of Alzheimer's disease biomarkers - Written for neuroscience researchers and clinicians studying or treating patients with Alzheimer's Disease - Integrates, in each chapter, the molecular/cellular abnormality due to Alzheimer's disease and the technological advancement of biomarkers techniques
Book Synopsis Cost Principles for Educational Institutions by : United States. Office of Management and Budget
Download or read book Cost Principles for Educational Institutions written by United States. Office of Management and Budget and published by . This book was released on 1979 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:
