Production of microparticles by supercritical antisolvent precipitation: process mechanisms and scale-up

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Publisher :
ISBN 13 : 9788887030709
Total Pages : 113 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Production of microparticles by supercritical antisolvent precipitation: process mechanisms and scale-up by : Iolanda De Marco

Download or read book Production of microparticles by supercritical antisolvent precipitation: process mechanisms and scale-up written by Iolanda De Marco and published by . This book was released on 2004 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Production on Mocroparticles by Supercritical Antisolvent Precipitation: Process Mechanisms and Scale-up

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Publisher :
ISBN 13 :
Total Pages : 113 pages
Book Rating : 4.:/5 (954 download)

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Book Synopsis Production on Mocroparticles by Supercritical Antisolvent Precipitation: Process Mechanisms and Scale-up by : Iolanda De Marco

Download or read book Production on Mocroparticles by Supercritical Antisolvent Precipitation: Process Mechanisms and Scale-up written by Iolanda De Marco and published by . This book was released on 2004 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Rapid Production of Micro- and Nano-particles Using Supercritical Water

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Publisher : Springer Science & Business Media
ISBN 13 : 3642129870
Total Pages : 109 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Rapid Production of Micro- and Nano-particles Using Supercritical Water by : Zhen Fang

Download or read book Rapid Production of Micro- and Nano-particles Using Supercritical Water written by Zhen Fang and published by Springer Science & Business Media. This book was released on 2010-07-24 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book details progress in use of supercritical water (SCW) to synthesize nano- and micro- oxides, inorganic salts and metal particles, and shows how polymer/biomass particles can be produced by the precipitation of solutes from SCW.

Current Trends of Supercritical Fluid Technology in Pharmaceutical, Nutraceutical and Food Processing Industries

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Publisher : Bentham Science Publishers
ISBN 13 : 1608050467
Total Pages : 124 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Current Trends of Supercritical Fluid Technology in Pharmaceutical, Nutraceutical and Food Processing Industries by : Ana Rita C. Duarte

Download or read book Current Trends of Supercritical Fluid Technology in Pharmaceutical, Nutraceutical and Food Processing Industries written by Ana Rita C. Duarte and published by Bentham Science Publishers. This book was released on 2010-07-13 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supercritical fluid technology can be seen as a green and environmentally friendly alternative to conventional. Current information on these topics is spread through different publications in different peer-reviewed journals. The editors were therefore of

Solubility in Supercritical Carbon Dioxide

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Publisher : CRC Press
ISBN 13 : 1420005995
Total Pages : 960 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Solubility in Supercritical Carbon Dioxide by : Ram B. Gupta

Download or read book Solubility in Supercritical Carbon Dioxide written by Ram B. Gupta and published by CRC Press. This book was released on 2006-12-06 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supercritical fluid extraction is an environmentally safe and cost-effective alternative to traditional organic solvents. Carbon dioxide is widely used as the solvent of choice for applications such as caffeine and nicotine extraction due to its mild critical temperature, nontoxicity, nonflammability, and low cost. Introducing the most complete col

Finely Dispersed Particles

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Publisher : CRC Press
ISBN 13 : 1420027662
Total Pages : 936 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Finely Dispersed Particles by : Aleksandar M. Spasic

Download or read book Finely Dispersed Particles written by Aleksandar M. Spasic and published by CRC Press. This book was released on 2005-10-14 with total page 936 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, the biggest advances in physical chemistry have come from thinking smaller. The leading edge in research pushes closer to the atomic frontier with every passing year. Collecting the latest developments in the science and engineering of finely dispersed particles and related systems, Finely Dispersed Particles: Micro-, Nano-, a

Supercritical Fluid Technology for Energy and Environmental Applications

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Publisher : Newnes
ISBN 13 : 0444626972
Total Pages : 285 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Supercritical Fluid Technology for Energy and Environmental Applications by : Vladimir Anikeev

Download or read book Supercritical Fluid Technology for Energy and Environmental Applications written by Vladimir Anikeev and published by Newnes. This book was released on 2013-12-21 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supercritical Fluid Technology for Energy and Environmental Applications covers the fundamental principles involved in the preparation and characterization of supercritical fluids (SCFs) used in the energy production and other environmental applications. Energy production from diversified resources — including renewable materials — using clean processes can be accomplished using technologies like SCFs. This book is focused on critical issues scientists and engineers face in applying SCFs to energy production and environmental protection, the innovative solutions they have found, and the challenges they need to overcome. The book also covers the basics of sub- and supercritical fluids, like the thermodynamics of phase and chemical equilibria, mathematical modeling, and process calculations.A supercritical fluid is any substance at a temperature and pressure above its critical point where distinct liquid and gas phases do not exist. At this state the compound demonstrates unique properties, which can be "fine-tuned," making them suitable as organic solvents in a range of industrial and laboratory processes.This volume enables readers to select the most appropriate medium for a specific situation. It helps instructors prepare course material for graduate and postgraduate courses in the area of chemistry, chemical engineering, and environmental engineering. And it helps professional engineers learn supercritical fluid-based technologies and use them in solving the increasingly challenging environmental issues. - Relates theory, chemical characteristics, and properties of the particular supercritical fluid to its various applications - Covers the fundamentals of supercritical fluids, like thermodynamics of phase and chemical equilibria, mathematical modeling, and process calculations - Includes the most recent applications of supercritical fluids, including energy generation, materials synthesis, and environmental protection

Mechanism of the Novel Antisolvent Vapour Precipitation (AVP) Process

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Publisher :
ISBN 13 :
Total Pages : 316 pages
Book Rating : 4.:/5 (11 download)

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Book Synopsis Mechanism of the Novel Antisolvent Vapour Precipitation (AVP) Process by : Jiunn Yuan Tan

Download or read book Mechanism of the Novel Antisolvent Vapour Precipitation (AVP) Process written by Jiunn Yuan Tan and published by . This book was released on 2015 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ultrafine spherical maltodextrin and maltose particles were successfully produced with the Antisolvent Vapour Precipitation (AVP) technique. Comparison between lactose and maltodextrin reaffirmed that a key requirement for the process is its ability to inhibit crystallization of the material. The precipitation process consists of: (1) an initial phase separation forming an emulsion, (2) phase inversion and (3) finally a water-maltodextrin shrinkage phase which forms the spherical particles driven by interfacial surface tension. Dehydrating the droplet at different stages of the process resulted in different particle morphologies; porous, smooth, microsphere network and microspheres. Higher ethanol relative humidity, higher ethanol absolute humidity and lower initial weight concentration were found to favour the formation of amorphous microspherical particles upon drying. A unique liquid phase separation was observed which leads to the proposed particle formation mechanism for the AVP process. Further quantitative study were conducted using a newly built vapour generation system, incorporating the LabView control and monitoring system and a new humidity measurement technique based on fundamental mass and energy balance. Analysis of the mass change of the droplet throughout the AVP drying process revealed a trend which suggests that the maximum ethanol concentration within the droplet may be the prevailing factor governing microsphere formation. In addition, an interesting observation on the final solid mass recorded for the porous and microsphere network structures showed that these structures exhibit liquid retention behaviour which could be useful for encapsulation applications.In order to better understand the mechanism of the AVP process, additional research was conducted to develop an AVP drying model to describe the simultaneous absorption and evaporation of ethanol and water within the droplet. This model was developed based on fundamental heat and mass transfer analysis and the incorporation of Raoult's Law and UNIFAC model to account for the binary interaction between water and ethanol. Comparison between the model and the experimental measurements revealed overestimation of ethanol absorption and total drying time. Further analysis suggests that this may be attributed to the counter diffusion of water and ethanol during the drying process and possibly non-Fickian diffusion behaviour of ethanol within the droplet. This work provides a fundamental basis for future work on modelling of this physical phenomenon.The mechanism and analysis provided in this work have contributed to a fundamental understanding of the AVP process in forming microspherical particles, which has potential application in drug delivery. Based on the mechanism proposed, the underlying principles of particle formation under AVP drying can be applied to other materials. The formation of porous and microsphere network, with high liquid retention behaviour suggests possible encapsulation application. In addition, the analysis and considerations employed for the AVP drying model provide a fundamental basis for further model development which would be useful in scaling up the AVP process.

Product, Process and Plant Design Using Subcritical and Supercritical Fluids for Industrial Application

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Publisher : Springer Nature
ISBN 13 : 303134636X
Total Pages : 262 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Product, Process and Plant Design Using Subcritical and Supercritical Fluids for Industrial Application by : Željko Knez

Download or read book Product, Process and Plant Design Using Subcritical and Supercritical Fluids for Industrial Application written by Željko Knez and published by Springer Nature. This book was released on 2023-07-03 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes cutting edge technology using supercritical fluids for the production of foodstuffs, medicals, and polymers. It illustrates the importance and use of basic data for design and operation at industrial scale units. The book's authors have several decades of experience of applied research on how to develop large scale industrial units. It provides readers complete insight in design and operation of industrial high pressure process plants. The book is written so it may be understood for people (with?) little or no background on high pressure process technology. It will provide information on how some foodstuffs, medicals, polymers are produced using high pressure technologies. The book demonstrates the importance of fundamental data, how to measure them and how to apply them to design industrial plants. At the same time, it also serves as a textbook for students.

Formulating Poorly Water Soluble Drugs

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Publisher : Springer Nature
ISBN 13 : 3030887197
Total Pages : 701 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Formulating Poorly Water Soluble Drugs by : Robert O. Williams III

Download or read book Formulating Poorly Water Soluble Drugs written by Robert O. Williams III and published by Springer Nature. This book was released on 2022-05-19 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

Advanced Supercritical Fluids Technologies

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Publisher : BoD – Books on Demand
ISBN 13 : 183880708X
Total Pages : 224 pages
Book Rating : 4.8/5 (388 download)

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Book Synopsis Advanced Supercritical Fluids Technologies by : Igor Pioro

Download or read book Advanced Supercritical Fluids Technologies written by Igor Pioro and published by BoD – Books on Demand. This book was released on 2020-05-20 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using SuperCritical Fluids (SCFs) in various processes is not new, because Mother Nature has been processing minerals in aqueous solutions at critical and supercritical pressures for billions of years. Somewhere in the 20th century, SCFs started to be used in various industries as working fluids, coolants, chemical agents, etc. Written by an international team of experts and complete with the latest research, development, and design, Advanced Supercritical Fluids Technologies is a unique technical book, completely dedicated to modern and advanced applications of supercritical fluids in various industries.Advanced Supercritical Fluids Technologies provides engineers and specialists in various industries dealing with SCFs as well as researchers, scientists, and students of the corresponding departments with a comprehensive overview of the current status, latest trends and developments of these technologies.Dr Igor Pioro is a professor at the University of Ontario Institute of Technology, Canada, and the Founding Editor of the ASME Journal of Nuclear Engineering and Radiation Science.

Carbon Dioxide Recovery and Utilization

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Publisher : Springer Science & Business Media
ISBN 13 : 9401702454
Total Pages : 422 pages
Book Rating : 4.4/5 (17 download)

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Book Synopsis Carbon Dioxide Recovery and Utilization by : M. Aresta

Download or read book Carbon Dioxide Recovery and Utilization written by M. Aresta and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carbon Dioxide Recovery and Utilization is a complete and informative resource on the carbon dioxide sources and market at the European Union level, with reference to the world situation. The book covers the following themes: - Sources of carbon dioxide and their purity, - Market of carbon dioxide and its uses, - Separation techniques of carbon dioxide from flue gases, - Analysis of the potential of each technique and application, - Basic science and technology of supercritical CO2, - Reactions in supercritical CO2 and its use as reactive solvent, - Utilization of CO2 in the synthesis of chemicals with low energy input, - Conversion of CO2 into fuels: existing techniques, - Dry reforming of methane, - Assessment of the use of carbon dioxide for the synthesis of methanol. This book is unique in providing integrated information and a perspective on innovative technologies for the use of carbon dioxide. The book is suitable for use as a textbook for courses in chemical engineering and chemistry. It is also of great interest as a general reference for those involved with technologies for avoiding carbon dioxide production and for economists. This is an invaluable reference for specialists on synthetic chemistry, gas separation, supercritical fluids, carbon dioxide marketing, renewable energy and sustainable development. In addition, it will be useful for those working in the chemical industry and for policy makers for carbon dioxide mitigation, innovative technologies, carbon recycling, and power generation.

Innovative Food Processing Technologies

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Publisher : Elsevier
ISBN 13 : 0128157828
Total Pages : 2482 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Innovative Food Processing Technologies by :

Download or read book Innovative Food Processing Technologies written by and published by Elsevier. This book was released on 2020-08-18 with total page 2482 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food process engineering, a branch of both food science and chemical engineering, has evolved over the years since its inception and still is a rapidly changing discipline. While traditionally the main objective of food process engineering was preservation and stabilization, the focus today has shifted to enhance health aspects, flavour and taste, nutrition, sustainable production, food security and also to ensure more diversity for the increasing demand of consumers. The food industry is becoming increasingly competitive and dynamic, and strives to develop high quality, freshly prepared food products. To achieve this objective, food manufacturers are today presented with a growing array of new technologies that have the potential to improve, or replace, conventional processing technologies, to deliver higher quality and better consumer targeted food products, which meet many, if not all, of the demands of the modern consumer. These new, or innovative, technologies are in various stages of development, including some still at the R&D stage, and others that have been commercialised as alternatives to conventional processing technologies. Food process engineering comprises a series of unit operations traditionally applied in the food industry. One major component of these operations relates to the application of heat, directly or indirectly, to provide foods free from pathogenic microorganisms, but also to enhance or intensify other processes, such as extraction, separation or modification of components. The last three decades have also witnessed the advent and adaptation of several operations, processes, and techniques aimed at producing high quality foods, with minimum alteration of sensory and nutritive properties. Some of these innovative technologies have significantly reduced the thermal component in food processing, offering alternative nonthermal methods. Food Processing Technologies: A Comprehensive Review, Three Volume Set covers the latest advances in innovative and nonthermal processing, such as high pressure, pulsed electric fields, radiofrequency, high intensity pulsed light, ultrasound, irradiation and new hurdle technology. Each section will have an introductory article covering the basic principles and applications of each technology, and in-depth articles covering the currently available equipment (and/or the current state of development), food quality and safety, application to various sectors, food laws and regulations, consumer acceptance, advancements and future scope. It will also contain case studies and examples to illustrate state-of-the-art applications. Each section will serve as an excellent reference to food industry professionals involved in the processing of a wide range of food categories, e.g., meat, seafood, beverage, dairy, eggs, fruits and vegetable products, spices, herbs among others.

SPR Catalysis V26

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849739188
Total Pages : 287 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis SPR Catalysis V26 by : Jerry Spivey

Download or read book SPR Catalysis V26 written by Jerry Spivey and published by Royal Society of Chemistry. This book was released on 2014-02-28 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 7000 papers are published in the field of catalysis each year. While the majority appear within a handful publications, keeping up with the literature can be difficult. Now in its 26th volume, the Specialist Periodical Report on Catalysis presents critical and comprehensive reviews of the hottest literature published over the last twelve months. Industrial and academic scientists face increasing challenges to find cost-effective and environmentally sound methods for converting natural resources into fuels, chemicals and energy. This series is edited by two leading researchers in the field and provides a balanced and in-depth review of the modern approaches to these challenges, covering major areas of heterogeneous and homogenous catalysis, as well as specific applications of catalysis, such as NOx control, kinetics and experimental techniques, such as microcalorimetry. With chapters detailing specific areas within the field, this series is a comprehensive reference for anyone working in Catalysis and an essential resource for any Library.

Handbook of Nanocelluloses

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Publisher : Springer Nature
ISBN 13 : 3030896218
Total Pages : 1081 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Handbook of Nanocelluloses by : Ahmed Barhoum

Download or read book Handbook of Nanocelluloses written by Ahmed Barhoum and published by Springer Nature. This book was released on 2022-07-15 with total page 1081 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Handbook covers the fundamental aspects, experimental setup, synthesis, properties, and characterization of different nanocelluloses. It also explores the technology challenges of nanocelluloses and the emerging applications and the global markets of nanocelluloses-based systems. In particular, this book: · Covers the history of nanocelluloses, types and classifications, fabrication techniques, critical processing parameters, physical and chemical properties, surface functionalization, and other treatments to allow practical applications. · Covers all recent aspects of nanocelluloses technologies, from experimental set-up to industrial applications. · Includes new physical, chemical and biological techniques for nanocelluloses fabrication, in-depth treatment of their surface functionalization, and characterization. · Discusses the unique properties of nanocelluloses that can be obtained by modifying their diameter, morphology, composition and dispersion in other materials. · Discusses the properties and morphology of several kinds of dispersion in polymeric materials, such as micro/nanofiberlated cellulose, cellulose nanofibers, cellulose nanocrystals, amorphous cellulose nanoparticles, and hybrid cellulose nanomaterials. · Presents the different techniques for dispersion, and self-assembly of polymeric materials, critical parameters of synthesis, modelling and simulation, and characterization methods. · Highlights a wide range of emerging applications of nanocelluloses, e.g. drug delivery, tissue engineering, medical implants, medical diagnostics and therapy, biosensors, catalysis, energy harvesting, energy storage, water/waste treatment, papermaking, textiles, construction industry, automotive, aerospace and many more. · Provides an outlook on the opportunities and challenges for the fabrication and manufacturing of nanocelluloses in industry. · Provides an in-depth look at the nature of nanocelluloses in terms of their applicability for industrial uses. · Provides in-depth insight and review on most recent types of nanocelluloses-based systems of unique structures and compositions. · Highlights the challenges and interdisciplinary perspective of nanocelluloses-based systems in science, biology, engineering, medicine, and technology, incorporating both fundamentals and applications. - Demonstrates how cutting-edge developments in nanofibers translate into real-world innovations in a range of industry sectors. This Handbook is a valuable reference for materials scientists, biologists, physicians, chemical, biomedical, manufacturing and mechanical engineers working in R&D industry and academia, who want to learn more about how nanocelluloses-based systems are commercially applied.

Pulmonary Drug Delivery Systems: Material and Technological Advances

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Publisher : Springer Nature
ISBN 13 : 9819919231
Total Pages : 465 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Pulmonary Drug Delivery Systems: Material and Technological Advances by : Piyush Pradeep Mehta

Download or read book Pulmonary Drug Delivery Systems: Material and Technological Advances written by Piyush Pradeep Mehta and published by Springer Nature. This book was released on 2023-07-21 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an insight into state-of-art developments in pulmonary drug delivery systems. It comprises several chapters covering a wide range of promising technologies and novel materials explored for developing effective pulmonary drug delivery systems. The initial book chapters elucidate role of thin film freezing, supercritical fluid technology, nano-in-micro particles system, crystal-engineered microstructures and porous particles in pulmonary drug delivery. The subsequent book chapters elaborate on various functional excipients such as chitosan, cyclodextrins, and Vitamin E-TPGS to attain local and systemic therapeutic action. There are book chapters focused on diverse novel carrier systems such as hydrogels, quantum dots, metal-organic framework, and prodrug approach. Additionally, book also contains chapters, exclusively dedicated to biologicals and numerical simulation in pulmonary therapeutics. The book chapters follow a sequential order, beginning with the pulmonary relevance of technology or polymeric materials, carrier synthesis schemes, current technical state-of-art, along with clinical, industrial, and regulatory aspects. Each chapter contains a future perspective section that will systematically reflect the current state of advances in pulmonary drug delivery. It also offers a practical basis for audience to understand the design and function of the delivery systems for better therapeutic outcomes. The book provides balanced views by considering the investigations from various scientific domains and industrial knowledge. Briefly, this book aims to collect, analyse, and bring together the latest developments in pulmonary drug delivery with more focus on materials and technologies. Indeed, this book is a valuable source for readers and researchers who wish to learn more about the advances in pulmonary drug delivery systems.

High Pressure Process Technology: Fundamentals and Applications

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Publisher : Elsevier
ISBN 13 : 0080533949
Total Pages : 684 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis High Pressure Process Technology: Fundamentals and Applications by : A. Bertucco

Download or read book High Pressure Process Technology: Fundamentals and Applications written by A. Bertucco and published by Elsevier. This book was released on 2001-10-15 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear evidence of increasing demands in the processing industry prompted the editors and authors to publish a new book about High Pressure Process Technology: Fundamentals and Applications.This book presents the latest knowledge regarding the high pressure processing aspects combined with that about the modeling, the design and the operation of safe and reliable high pressure plants and equipment. This treatment and selection of the subjects is stimulating and unique. Consisting of nine chapters, each subdivided into several sections, the book addresses the high pressure aspects, providing well selected correlated information connected with a comprehensive overview together with a large number of references. The main body of the first eight chapters refers to subjects like high pressure in general, the thermodynamics and kinetics of the fluids involved, the design of high pressure equipment, the modeling and design of reactors, separation and fractionation units, the safety aspects, the control and economics.In the extended last chapter, examples of promising high pressure applications are explained, such as chemical and enzymatic reactions in supercritical solvents, hydrogenation under supercritical conditions, supercritical water oxidation, polymerization with metallocene catalysts, supercritical extraction, fractionation and precipitation, supercritical pharma processing, ultra-high pressure sterilization and supercritical dry-cleaning.