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Proceedings Of The Second International Pharmacological Meeting Recent Advances In The Pharmacology Of Toxins
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Book Synopsis Recent Advances in the Pharmacology of Toxins by : H. W. Raudonat
Download or read book Recent Advances in the Pharmacology of Toxins written by H. W. Raudonat and published by Elsevier. This book was released on 2013-10-22 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in the Pharmacology of Toxins brings together the proceedings of the Second International Pharmacological Meeting of the International Union of Physiological Sciences, held in Prague, Czechoslovakia, on August 20-23, 1963. The meeting provided a forum for discussing advances in the understanding of the pharmacology of toxins and addressed topics ranging from antagonists of bradykinin to the mode of the spread of tetanus toxin in experimental animals. This volume is comprised of 28 chapters and begins with an analysis of the effects of toxins from microorganisms on mammalian cellular metabolism and structure, followed by a review of SRS-A, a slow-reacting substance of anaphylaxis, as a potential factor in the symptoms produced by venoms and toxins. Subsequent chapters explore the release of pharmacologically active lipids by enzymes contained in toxins; the structure and function of some enzymes in snake venoms, with reference to disulfide linkages; biochemistry and pharmacology of small-molecular compounds of cobra venom; and the role of ganglioside in the mode of action of tetanus toxin. This book will be of particular value to pharmacologists and physiologists.
Book Synopsis Proceedings of the Second International Pharmacological Meeting: Evaluation of new drugs in man by :
Download or read book Proceedings of the Second International Pharmacological Meeting: Evaluation of new drugs in man written by and published by . This book was released on 1965 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Psychopharmacology Abstracts written by and published by . This book was released on 1965 with total page 874 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Improving and Accelerating Therapeutic Development for Nervous System Disorders by : Institute of Medicine
Download or read book Improving and Accelerating Therapeutic Development for Nervous System Disorders written by Institute of Medicine and published by National Academies Press. This book was released on 2014-02-06 with total page 107 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.
Book Synopsis Proceedings of the Third International Pharmacological Meeting: Mechanisms of drug toxicity by :
Download or read book Proceedings of the Third International Pharmacological Meeting: Mechanisms of drug toxicity written by and published by . This book was released on 1968 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis International Pharmacological Meeting, 3d, Sao Paulo, 1966: Mechanisms of drug toxicity [edited by] H. Rasková by : Mauricio Rocha e Silva
Download or read book International Pharmacological Meeting, 3d, Sao Paulo, 1966: Mechanisms of drug toxicity [edited by] H. Rasková written by Mauricio Rocha e Silva and published by . This book was released on 1968 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Mechanisms of Drug Toxicity by : H. Rašková
Download or read book Mechanisms of Drug Toxicity written by H. Rašková and published by Elsevier. This book was released on 2013-10-22 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mechanisms of Drug Toxicity, Volume 4 presents the proceedings of the 3rd International Pharmacological Meeting held in Sao Paulo, Brazil in 1966. The book discusses the drug-induced pathobiotic effects; the mechanisms of adverse reactions; and enzyme induction in the mechanism of chronic toxicity. The text also describes the influence of inducing substances on the growth of liver and microsomal electron transport systems; the quantitative aspects of chronic toxicity; and the facts and fallacies in predicting drug effects in human.
Book Synopsis Immunopharmacology by : H. O. Schild
Download or read book Immunopharmacology written by H. O. Schild and published by Elsevier. This book was released on 2017-01-31 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunopharmacology is the 11th volume of the proceedings of the Third International Pharmacological Meeting held at Sao Paulo, Brazil on July 26, 1966. The volume covers papers that deal with immunoglobulins responsible for hypersensitivity reactions and with the mechanisms of these reactions; pharmacological mediators of immediate and delayed hypersensitivity; Arthus reactions; and soluble factors released by the action of antigen on sensitized lymphocytes. The book concludes with a single paper on the subject of penicillin allergy. Immunologists and pharmacologists will find the volume invaluable.
Book Synopsis Pharmacology of Pain by : R. K. S. Lim
Download or read book Pharmacology of Pain written by R. K. S. Lim and published by Elsevier. This book was released on 2016-07-29 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology of Pain, Volume 9 presents the proceedings of the 3rd International Pharmacological Meetings held in Sao Paulo in 1966. The book includes papers on the mediators of pain; proteolytic enzymes as mediators of pain; and desensitization with capsaicin and related acylamides as a tool for studying the function of pain receptors. The text also covers the sensitization of nociceptors by 5-hydroxytryptamine in man; the possible role of serotonin in affective component of pain behavioral reaction in the rat; and the use of pain induced functional impairment for assessing analgesic action. Papers on the clinical pharmacology of analgesics and analgesic antagonists; behavioral mechanisms of human pain; and central nervous mechanisms involved in pain and analgesia are also considered. The book further tackles the neuropharmacology of pain and analgesia; the interrelationship of cortical and subcortical pain systems; and the interaction of fast- and slow-conducting fiber systems involved in pain and analgesia.
Book Synopsis National Library of Medicine Current Catalog by : National Library of Medicine (U.S.)
Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Book Synopsis Salt and Water Balance by : K. H. Beyer
Download or read book Salt and Water Balance written by K. H. Beyer and published by Elsevier. This book was released on 2013-10-08 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: Salt and Water Balance, Volume 8 presents the proceedings of the 3rd International Pharmacological Meeting, held in Sao Paulo, Brazil, on July 24–30, 1966. This book features the modulation of renal control of electrolyte and water balance, which is the most effective approach of handling most clinical problems wherein fluid retention needs to be reduced. Comprised of 10 chapters, this compilation of papers starts with an overview of the diuretic agents that are effective diuretic therapy. This text then describes the active transport, which proceeds at the expense of energy against the combined chemical and electrical gradients in the case of electrolytes. Other chapters consider the historical importance in therapy and the mechanisms of action of mercurial diuretics. This book discusses as well the complications and unwanted side effects of diuretic therapy. The final chapter deals with the hemodynamic mechanisms and their possible influence on the tubular function. This book is a valuable resource for physicians, health care professionals, and patients.
Book Synopsis The Control of Growth Processes by Chemical Agents by : A. D. Welch
Download or read book The Control of Growth Processes by Chemical Agents written by A. D. Welch and published by Elsevier. This book was released on 2013-10-22 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Control of Growth Processes by Chemical Agents covers the proceedings of the 1966 Third International Pharmacological Meeting on Control of Growth Processes by Chemical Agents, held in Sao Paolo, Brazil. This book is composed of seven chapters, and begins with a survey of the comparative biology of dihydrofolate reductases as a basis for chemotherapy. The succeeding chapters deal with the mechanism of pyrimidine metabolism as a chemotherapeutic target and the biochemical and biological research works with arabinoforanosyl cytosine, known as cytarabine. These chapters specifically describe the cytotoxicity and antitumor activity of cytarabine. The remaining chapters discuss the advances in viral chemotherapy and the regulatory mechanisms of enzyme synthesis and their alteration in malignancy. This book will be of value to biologists, biochemists, and oncologists.
Book Synopsis Pharmacology of Cholinergic and Adrenergic Transmission by : G. B. Koelle
Download or read book Pharmacology of Cholinergic and Adrenergic Transmission written by G. B. Koelle and published by Elsevier. This book was released on 2017-01-31 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 3: Pharmacology of Cholinergic and Adrenergic Transmission focuses on the effects of drugs on muscles, nerve fibers, and the central nervous system. The selection first offers information on the role of sodium ions in the release of acetylcholine and the distribution and release of acetylcholine in muscles. Discussions focus on the effects of sodium deficiency on ACh release in perfused ganglia; effects of sodium pump inhibitors on ganglionic and myoneural transmission; distribution of ACh and choline acetylase in muscle; and ACh release after denervation. The text then ponders on the roles of acetylcholine and acetylcholinesterase in junctional transmission and correlated studies of monoamines and acetylcholinesterase in sympathetic ganglia, manifesting the distribution of adrenergic and cholinergic neurons. The publication examines the action of acetylcholine and related drugs on mammalian nonmyelinated nerve fibers; possible mechanisms of acetylcholine action in muscles; and electrophysiological analysis of cholinergic transmission in sympathetic ganglia. The text then reviews the interactions of cholinomimetic and cholinergic blocking drugs at sympathetic ganglia; evolution of cholinoreceptive sites of locomotor muscle; and pharmacological blocking of central cholinoreactive systems and the possibilities of its therapeutic application. The selection is a dependable source of data for readers interested in the pharmacology of cholinergic and adrenergic transmission.
Book Synopsis Proceedings of the Third International Pharmacological Meeting: Clinical evaluation of drugs by :
Download or read book Proceedings of the Third International Pharmacological Meeting: Clinical evaluation of drugs written by and published by . This book was released on 1968 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Physico-Chemical Aspects of Drug Action by : E. J. Ariëns
Download or read book Physico-Chemical Aspects of Drug Action written by E. J. Ariëns and published by Elsevier. This book was released on 2017-05-17 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physico-Chemical Aspects of Drug Action, Volume 7 covers topics on drug kinetics and the overall physicochemical properties of the drug in relation therewith, and the physicochemical aspects of the drug-receptor interaction, putting emphasis on receptor mechanisms and specific properties required for certain types of drugs in this respect. The book starts with some contributions dealing with various general aspects of drug kinetics followed by some contributions dealing with the relationship between certain physicochemical properties of drug molecules and their action. The text describes the pharmacokinetics and dose-concentration relationships; the time course of the biological response to drugs; and the empirical equations for correlating biological efficiency of organic compounds. The text also describes molecular basis for the action of chemotherapeutic drugs; the structure-activity studies on sulphonamides; and the water extrusion hypothesis. The mathematical treatment of two-point attachment between drug and receptor; the molecular properties and biological activity of catecholamines and certain related compounds; and the structure-activity relationships of diarylcarbinolethers are also considered. The book further tackles quantum mechanically-derived electronic distributions in the conformers of 2-pam; and the molecular basis for the action of certain drugs in the central nervous system. Pharmacologists and chemists will find the book invaluable.
Book Synopsis Proceedings of the Third International Pharmacological Meeting: Pharmacology and pain by :
Download or read book Proceedings of the Third International Pharmacological Meeting: Pharmacology and pain written by and published by . This book was released on 1968 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Proceedings written by and published by . This book was released on 1966 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
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