Precision in Pulmonary, Critical Care, and Sleep Medicine

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Author :
Publisher : Springer Nature
ISBN 13 : 303031507X
Total Pages : 430 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Precision in Pulmonary, Critical Care, and Sleep Medicine by : Jose L. Gomez

Download or read book Precision in Pulmonary, Critical Care, and Sleep Medicine written by Jose L. Gomez and published by Springer Nature. This book was released on 2020-01-30 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine. It combines fundamental concepts of the field with state-of-the-art studies and how they translate into individual preventive, diagnostic and therapeutic plans. Precision medicine is focused on the integration of individual variability with disease prevention and treatment principles derived from population studies. This concept has risen to prominence in recent years in parallel with advances in genetics, molecular diagnostics and novel target-specific therapies. This fundamental shift in the approach to treatment has broad implications in how we prevent, diagnose and treat disease. Describing key concepts of precision medicine and relating these to pulmonary, critical care and sleep disorders is essential to educate relevant stakeholders and increase the impact of pulmonary precision medicine. The book is organized into seven sections: introduction; genetics; biomarkers; precise phenotyping; mobile health, wearables and telemedicine; precision therapeutics; and enabling widespread adoption of precision medicine. The chapters are organized with an introduction to the specific theme, followed by its basic concepts. They then delve into how these basic concepts relate to the larger theme of precision medicine, new precision medicine approaches to dealing with these problems, and key takeaway points. Liberally illustrated with images, figures, and tables, the text is thorough and intuitive for clinicians and researchers to learn the processes and applications of precision medicine. This is an ideal guide for clinicians to learn new precision medicine concepts in the fields of genetics, genomics, mobile health, and how they apply to their practice and their patients, as well as researchers seeking a basic understanding of precision medicine to assist in designing future research studies.

Medical Education in Pulmonary, Critical Care, and Sleep Medicine

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Author :
Publisher : Springer
ISBN 13 : 3030106802
Total Pages : 299 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Medical Education in Pulmonary, Critical Care, and Sleep Medicine by : Patricia A. Kritek

Download or read book Medical Education in Pulmonary, Critical Care, and Sleep Medicine written by Patricia A. Kritek and published by Springer. This book was released on 2019-05-14 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a book for clinician educators. It offers modern, evidence-based practices to use in teaching learners at a range of levels, with an emphasis on concrete strategies that teachers can implement in their own clinical practices as well as in small and large group settings. Medical education is rapidly changing with emerging evidence on best practices and a proliferation of new technologies. As strategies for effectively teaching medical learners evolve, it is important to understand the implications for Pulmonary, Critical Care, and Sleep Medicine (PCCM). This text is structured to allow easy access to the reader. Chapters are organized around level of learner (e.g., medical student to PCCM fellow to practicing physicians) as well as the location of teaching. Given the variety of clinical settings in which PCCM physicians teach, specific consideration of best practices, broad changes in curricular design and pedagogy are considered in different clinical contexts. Each chapter begins with a focus on why the topic is important for clinician educators. A review of the available evidence and relevant medical education theory about the topic follows, with examples from specific studies that provide insight into best practices regarding the concepts and topics discussed in the chapter. For chapters focusing on learners, different environments are considered and similarly, if the focus is on the learning environment, attention is paid to the approach to different learners. Each chapter ends with a summary of the primary points from the chapter and concrete examples of how clinician teachers can put the concepts discussed in the chapter into practice. This is an ideal guide for educators in pulmonary, critical care, and sleep medicine.

Precision Sleep Medicine, An Issue of Sleep Medicine Clinics

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323682634
Total Pages : pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Precision Sleep Medicine, An Issue of Sleep Medicine Clinics by : Susheel Patil

Download or read book Precision Sleep Medicine, An Issue of Sleep Medicine Clinics written by Susheel Patil and published by Elsevier Health Sciences. This book was released on 2019-08-07 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Sleep Medicine Clinics, edited by Dr. Susheel Patil in collaboration with Consulting Editor, Teogilo Lee-Chiong, is devoted to Precision Sleep Medicine. Topics covered in this issue include: The Promise of Precision Medicine in Sleep Medicine; Precision Medicine for Obstructive Sleep Apnea; Precision Medicine for Pediatric Obstructive Sleep Apnea; Precision Medicine for Hypersomnia; Precision Medicine for Insomnia; iCBTi: Tailoring CBTi for Chronic Insomnia Patients; Sleep Loss; Precision Medicine for REM Behavior Disorder; NREM Parasomnia: The Promise of Precision Medicine; Sleep Pharmacogenetics: The Promise of Precision Medicine; and Sleep and Memory: The Promise of Precision Medicine.

Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care

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Publisher : Springer Nature
ISBN 13 : 3030429989
Total Pages : 530 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care by : Antonio M. Esquinas

Download or read book Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care written by Antonio M. Esquinas and published by Springer Nature. This book was released on 2020-05-28 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to a comprehensive analysis of recent advances and clinical research in noninvasive mechanical ventilation (NIV) in Pulmonary, Critical Care, and Sleep Medicine. The objective of the book is to increase the knowledge and understanding of the reader in the best clinical practice in three main sections. A selected international group of experts in the field of noninvasive ventilation formed a panel to provide an update on the recent literature in the application and efficient utilization of NIV in Pulmonary, Critical Care, and Sleep Medicine. Each particular section will discuss the application of NIV in different disease process. The authors summarized the main results of the recent trials, clinical and technological advances, expert opinions, and practical guidelines. Chapters, summarized by expert committee, provide a “deep and exhaustive critical analysis and summary” of the recent advances in the field of NIV, presented as key points and/recommendations for the best clinical practice from articles published in the last decade. The content of the book will serve as a resource and a tool to the practicing physicians toward NIV. Main objective is to increase their proficiency in management of different pathophysiological aspects of the respiratory system. In this line, the book offers to the readers, who are seeking the latest recommendations, the future research directions in noninvasive mechanical ventilation. Table of contents describe and analyze, the items trend setters in noninvasive ventilation, organized in three main sections, “pulmonary”, “critical care” and “sleep medicine”, using the primary keyword related with term “noninvasive mechanical ventilation” as search term associated with “secondary keywords” studies from a period of 2018 to 2019. This searching methodology and analysis define this unique book to the approach in noninvasive mechanical ventilation for best clinical practice, research, clinical study designs and critical analysis, how noninvasive ventilation is current and trending. Based on this form of conception of book updated, editors and authors consider that this book opens a new and original vision for adequate knowledge and deep updated based on key publications in the period under review, very useful for clinical practice, studies designs and potential new trends in the use of noninvasive ventilation. As such, it is a unique update book resource in noninvasive ventilation in pulmonary, critical care and sleep medicine that may influence current clinical practice and future studies. With ultimate goal is better care and outcome for our patients.

Precision Medicine: A Multidisciplinary Approach

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Publisher : Elsevier Health Sciences
ISBN 13 : 032378948X
Total Pages : 289 pages
Book Rating : 4.3/5 (237 download)

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Book Synopsis Precision Medicine: A Multidisciplinary Approach by : Joel J. Heidelbaugh

Download or read book Precision Medicine: A Multidisciplinary Approach written by Joel J. Heidelbaugh and published by Elsevier Health Sciences. This book was released on 2020-12-18 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Clinics Collections titles take a multidisciplinary approach to today’s practice of medicine, selecting the most recent and relevant articles from the Clinics series and combining them into a single source of information on a focused topic. Articles are chosen from multiple Clinics to highlight the range of specialties covering major medical issues, delivering the information needed for successful interdisciplinary teamwork and effective patient care. Written from a variety of medical perspectives, these articles offer deeper insight into how each specialty cares for its patients and provide a unique entry into sharing best concepts for the entire medical team. Clinics Collections: Precision Medicine draws from Elsevier’s Clinics Review Articles database to provide today’s medical teams with practical clinical advice and insights on this timely medical model. It guides readers on how to apply current primary research findings to everyday practice, keep up with new and improved treatment methods, and improve patient outcomes. Areas of focus include breast cancer, lung cancer, melanoma, arthritis, sleep medicine, and pediatric oncology. Each article begins with keywords and key points for immediate access to the most critical information. Articles are presented in an easy-to-digest and concisely worded format.

Advances in Applications of Data-Driven Computing

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Author :
Publisher : Springer Nature
ISBN 13 : 9813369191
Total Pages : 187 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Advances in Applications of Data-Driven Computing by : Jagdish Chand Bansal

Download or read book Advances in Applications of Data-Driven Computing written by Jagdish Chand Bansal and published by Springer Nature. This book was released on 2021-04-16 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to foster machine and deep learning approaches to data-driven applications, in which data governs the behaviour of applications. Applications of Artificial intelligence (AI)-based systems play a significant role in today’s software industry. The sensors data from hardware-based systems making a mammoth database, increasing day by day. Recent advances in big data generation and management have created an avenue for decision-makers to utilize these huge volumes of data for different purposes and analyses. AI-based application developers have long utilized conventional machine learning techniques to design better user interfaces and vulnerability predictions. However, with the advancement of deep learning-based and neural-based networks and algorithms, researchers are able to explore and learn more about data and their exposed relationships or hidden features. This new trend of developing data-driven application systems seeks the adaptation of computational neural network algorithms and techniques in many application domains, including software systems, cyber security, human activity recognition, and behavioural modelling. As such, computational neural networks algorithms can be refined to address problems in data-driven applications. Original research and review works with model and build data-driven applications using computational algorithm are included as chapters in this book.

Principles and Practice of Sleep Medicine E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323377521
Total Pages : 2542 pages
Book Rating : 4.3/5 (233 download)

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Book Synopsis Principles and Practice of Sleep Medicine E-Book by : Meir H. Kryger

Download or read book Principles and Practice of Sleep Medicine E-Book written by Meir H. Kryger and published by Elsevier Health Sciences. This book was released on 2015-12-29 with total page 2542 pages. Available in PDF, EPUB and Kindle. Book excerpt: For nearly 30 years, Dr. Meir Kryger’s must-have guide to sleep medicine has been the gold standard in this fast-changing field. This essential, full-color reference includes more than 20 unique sections and over 170 chapters covering every aspect of sleep disorders, giving you the authoritative guidance you need to offer your patients the best possible care. Evidence-based content helps you make the most well-informed clinical decisions. An ideal resource for preparing for the sleep medicine fellowship examination. New content on sleep apnea, neurological disorders, legal aspects of sleep medicine, dental sleep medicine genetics, circadian disorders, geriatrics, women’s health, cardiovascular diseases, and occupational sleep medicine, keeps you fully up to date. Updates to scientific discoveries and clinical approaches ensure that you remain current with new knowledge that is advancing the diagnosis and management of sleep disorders. Online access to additional resources, including 95 video clips and over 950 self-assessment questions.

Sleep and Breathing Disorders E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323478565
Total Pages : 408 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Sleep and Breathing Disorders E-Book by : Meir H. Kryger

Download or read book Sleep and Breathing Disorders E-Book written by Meir H. Kryger and published by Elsevier Health Sciences. This book was released on 2016-07-01 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written specifically for non-sleep medicine specialists, this one-of-a-kind reference guides you through every aspect of this complex field with authoritative advice from Dr. Meir Kryger and other experts. Vibrantly illustrated in full color, it thoroughly covers the types of patients you’re most likely to see in the outpatient setting and brings you up to date with the latest treatment methods, both surgical and non-surgical. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Complete coverage of the patients you’re most likely to encounter, including special populations such as those with COPD, obesity hypoventilation, pregnancy, neuromuscular disorders, stroke, and more. Specific information on topics of interest to a wide variety of physicians: heart failure and sleep disordered breathing; surgical treatments, including hypoglossal nerve stimulation; oral appliances and the treatment of sleep apnea; home sleep testing; and different types of PAP devices. Ideal for pulmonologists, otolaryngologists, cardiologists, primary care physicians, dentists, and other healthcare providers who encounter patients with sleep and breathing disorders. Full-color illustrations throughout, including a profusely illustrated chapter on physical diagnosis.

Novel Approaches to the Management of Sleep-Disordered Breathing, An Issue of Sleep Medicine Clinics, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323446353
Total Pages : 137 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Novel Approaches to the Management of Sleep-Disordered Breathing, An Issue of Sleep Medicine Clinics, E-Book by : Neil Freedman

Download or read book Novel Approaches to the Management of Sleep-Disordered Breathing, An Issue of Sleep Medicine Clinics, E-Book written by Neil Freedman and published by Elsevier Health Sciences. This book was released on 2016-06-11 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Sleep Medicine Clinics focuses on Novel Therapies for Sleep-Disorderd Breathing. Article topics include: The problems and pitfalls with current approaches to managing sleep disordered breathing; New approaches to diagnosing sleep disordered breathing; Monitoring progress and adherence with PAP therapy for OSA; The future of dental approaches for the treatment of OSA; Pharmacologic approaches for the treatment of OSA; Novel therapies for the treatment of central sleep apnea; Advances and new approaches to managing sleep disordered breathing related to chronic pulmonary disease; The role of big data in the management of sleep disordered breathing; Using genes and biomarkers to assess risk and identify optimal treatments for patients with sleep disordered breathing, and more!

Pulmonary Fibrosis

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Publisher : Frontiers Media SA
ISBN 13 : 2889631958
Total Pages : 136 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Pulmonary Fibrosis by : Argyrios Tzouvelekis

Download or read book Pulmonary Fibrosis written by Argyrios Tzouvelekis and published by Frontiers Media SA. This book was released on 2019-11-14 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Precision Approaches to Heterogeneity in Asthma

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Author :
Publisher : Springer Nature
ISBN 13 : 3031322592
Total Pages : 416 pages
Book Rating : 4.0/5 (313 download)

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Book Synopsis Precision Approaches to Heterogeneity in Asthma by : Allan R. Brasier

Download or read book Precision Approaches to Heterogeneity in Asthma written by Allan R. Brasier and published by Springer Nature. This book was released on 2023-07-18 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a common chronic respiratory disease that causes substantial morbidity and has been challenging to treat due to its heterogeneous onset, environmental triggers, severity, and treatment response. To update the field on the rapid advances in this field, Precision Approaches to Heterogeneity in Asthma follows its highly successful predecessor, Heterogeneity in Asthma. In this new volume, noted authorities Allan R Brasier and Nizar N Jarjour and a cadre of leaders in the field incorporate new work advancing our understanding of phenotypes (endotypes) of disease, regional variations in ventilation, systems approach to analyzing the findings from studies of inducible phenotypes, and emerging results of biomarker-informed clinical trials. This work will facilitate our current understanding of the spectrum of disease etiology, prognosis, and the likelihood of responding to the range of available therapeutic interventions.

Asthma

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Publisher : Springer Nature
ISBN 13 : 1071623648
Total Pages : 337 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Asthma by : Magdalena M. Gorska

Download or read book Asthma written by Magdalena M. Gorska and published by Springer Nature. This book was released on 2022-06-30 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details a collection of laboratory protocols to study asthma in mice and humans. Chapters cover animal models of asthma, methods to measure asthma-related molecules, protocols to detect, isolate, culture and stimulate cells that contribute to asthma in mice and humans, methods to deplete these cells in vivo and study responses of intact airway tissues ex vivo. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Asthma: Methods and Protocols aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.

Deep Learning for Chest Radiographs

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Publisher : Elsevier
ISBN 13 : 0323906869
Total Pages : 230 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Deep Learning for Chest Radiographs by : Yashvi Chandola

Download or read book Deep Learning for Chest Radiographs written by Yashvi Chandola and published by Elsevier. This book was released on 2021-07-16 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep Learning for Chest Radiographs enumerates different strategies implemented by the authors for designing an efficient convolution neural network-based computer-aided classification (CAC) system for binary classification of chest radiographs into "Normal" and "Pneumonia." Pneumonia is an infectious disease mostly caused by a bacteria or a virus. The prime targets of this infectious disease are children below the age of 5 and adults above the age of 65, mostly due to their poor immunity and lower rates of recovery. Globally, pneumonia has prevalent footprints and kills more children as compared to any other immunity-based disease, causing up to 15% of child deaths per year, especially in developing countries. Out of all the available imaging modalities, such as computed tomography, radiography or X-ray, magnetic resonance imaging, ultrasound, and so on, chest radiographs are most widely used for differential diagnosis between Normal and Pneumonia. In the CAC system designs implemented in this book, a total of 200 chest radiograph images consisting of 100 Normal images and 100 Pneumonia images have been used. These chest radiographs are augmented using geometric transformations, such as rotation, translation, and flipping, to increase the size of the dataset for efficient training of the Convolutional Neural Networks (CNNs). A total of 12 experiments were conducted for the binary classification of chest radiographs into Normal and Pneumonia. It also includes in-depth implementation strategies of exhaustive experimentation carried out using transfer learning-based approaches with decision fusion, deep feature extraction, feature selection, feature dimensionality reduction, and machine learning-based classifiers for implementation of end-to-end CNN-based CAC system designs, lightweight CNN-based CAC system designs, and hybrid CAC system designs for chest radiographs. This book is a valuable resource for academicians, researchers, clinicians, postgraduate and graduate students in medical imaging, CAC, computer-aided diagnosis, computer science and engineering, electrical and electronics engineering, biomedical engineering, bioinformatics, bioengineering, and professionals from the IT industry. Provides insights into the theory, algorithms, implementation, and application of deep-learning techniques for medical images such as transfer learning using pretrained CNNs, series networks, directed acyclic graph networks, lightweight CNN models, deep feature extraction, and conventional machine learning approaches for feature selection, feature dimensionality reduction, and classification using support vector machine, neuro-fuzzy classifiers Covers the various augmentation techniques that can be used with medical images and the CNN-based CAC system designs for binary classification of medical images focusing on chest radiographs Investigates the development of an optimal CAC system design with deep feature extraction and classification of chest radiographs by comparing the performance of 12 different CAC system designs

Comprehensive Toxicology

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Publisher : Elsevier
ISBN 13 : 0081006128
Total Pages : 8639 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Comprehensive Toxicology by :

Download or read book Comprehensive Toxicology written by and published by Elsevier. This book was released on 2017-12-01 with total page 8639 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology. Organized to cover both the fundamental principles of toxicology and unique aspects of major organ systems Thoroughly revised to include the latest advances in the toxicological effects of chemicals on the immune system Features additional coverage throughout and a new volume on toxicology of the hematopoietic system Presents in-depth, comprehensive coverage from an international author base of domain experts

Annual Update in Intensive Care and Emergency Medicine 2023

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Publisher : Springer Nature
ISBN 13 : 3031230051
Total Pages : 540 pages
Book Rating : 4.0/5 (312 download)

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Book Synopsis Annual Update in Intensive Care and Emergency Medicine 2023 by : Jean-Louis Vincent

Download or read book Annual Update in Intensive Care and Emergency Medicine 2023 written by Jean-Louis Vincent and published by Springer Nature. This book was released on 2023-03-24 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Annual Update compiles reviews of the most recent developments in clinical intensive care and emergency medicine research and practice in one comprehensive book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in intensive care and emergency medicine, anesthesia, surgery, internal medicine, and pediatrics.

Data Science in Critical Care, An Issue of Critical Care Clinics, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0443181942
Total Pages : 217 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Data Science in Critical Care, An Issue of Critical Care Clinics, E-Book by : Rishikesan Kamaleswaran

Download or read book Data Science in Critical Care, An Issue of Critical Care Clinics, E-Book written by Rishikesan Kamaleswaran and published by Elsevier Health Sciences. This book was released on 2023-09-13 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue of Critical Care Clinics, guest editors Drs. Rishikesan Kamaleswaran and Andre L. Holder bring their considerable expertise to the topic of Data Science in Critical Care. Data science, the field of study dedicated to the principled extraction of knowledge from complex data, is particularly relevant in the critical care setting. In this issue, top experts in the field cover key topics such as refining our understanding and classification of critical illness using biomarker-based phenotyping; predictive modeling using AI/ML on EHR data; classification and prediction using waveform-based data; creating trustworthy and fair AI systems; and more. Contains 15 relevant, practice-oriented topics including AI and the imaging revolution; designing “living, breathing clinical trials: lessons learned from the COVID-19 pandemic; the patient or the population: knowing the limitations of our data to make smart clinical decisions; weighing the cost vs. benefit of AI in healthcare; and more. Provides in-depth clinical reviews on data science in critical care, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Veterans and Agent Orange

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Author :
Publisher : National Academies Press
ISBN 13 : 0309380693
Total Pages : 1115 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Veterans and Agent Orange by : National Academies of Sciences, Engineering, and Medicine

Download or read book Veterans and Agent Orange written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-03-29 with total page 1115 pages. Available in PDF, EPUB and Kindle. Book excerpt: From 1962 to 1971, the US military sprayed herbicides over Vietnam to strip the thick jungle canopy that could conceal opposition forces, to destroy crops that those forces might depend on, and to clear tall grasses and bushes from the perimeters of US base camps and outlying fire-support bases. Mixtures of 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), picloram, and cacodylic acid made up the bulk of the herbicides sprayed. The main chemical mixture sprayed was Agent Orange, a 50:50 mixture of 2,4-D and 2,4,5-T. At the time of the spraying, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic form of dioxin, was an unintended contaminant generated during the production of 2,4,5-T and so was present in Agent Orange and some other formulations sprayed in Vietnam. Because of complaints from returning Vietnam veterans about their own health and that of their children combined with emerging toxicologic evidence of adverse effects of phenoxy herbicides and TCDD, the National Academy of Sciences was asked to perform a comprehensive evaluation of scientific and medical information regarding the health effects of exposure to Agent Orange, other herbicides used in Vietnam, and the various components of those herbicides, including TCDD. Updated evaluations were conducted every two years to review newly available literature and draw conclusions from the overall evidence. Veterans and Agent Orange: Update 2014 is a cumulative report of the series thus far.