Postsynaptic Voltage-sensititve Mechanisms in Rat Hippocampal CA1 Neurons Underlying Synaptic Plasticity and Intergration

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ISBN 13 :
Total Pages : 302 pages
Book Rating : 4.:/5 (29 download)

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Book Synopsis Postsynaptic Voltage-sensititve Mechanisms in Rat Hippocampal CA1 Neurons Underlying Synaptic Plasticity and Intergration by : Roberto Malinow

Download or read book Postsynaptic Voltage-sensititve Mechanisms in Rat Hippocampal CA1 Neurons Underlying Synaptic Plasticity and Intergration written by Roberto Malinow and published by . This book was released on 1986 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Neural Plasticity and Memory

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Publisher : CRC Press
ISBN 13 : 1420008412
Total Pages : 368 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Neural Plasticity and Memory by : Federico Bermudez-Rattoni

Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq

Synaptic Function

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Publisher : Wiley-Interscience
ISBN 13 :
Total Pages : 808 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Synaptic Function by : Neurosciences Institute (New York, N.Y.)

Download or read book Synaptic Function written by Neurosciences Institute (New York, N.Y.) and published by Wiley-Interscience. This book was released on 1987 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book consists of five sections. The first section details methods for analyzing both presynaptic and postsynaptic function and emphasizes the molecular aspects of synapses. It describes ongoing studies of neurotransmitter release, voltage- sensitive ion channels, and electronic transmission at gap junctions. The second section focuses on the growing menagerie of neurotransmitters: their catagorization into chemical families, their relation to ion channels, their modulation by second messenger systems and their role in pharmacologic action. The third section considers the important relationship of transmitter diversity and synaptic types to the behavior of actual cellular networks. All of the studies described in these sections point to the necessity of considering interactions between anatomy, chemistry, physiology and pharmacology if synaptic function is to be understood at any one of these levels of analysis.

Neurotransmitter Release

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Publisher : Oxford University Press, USA
ISBN 13 :
Total Pages : 466 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Neurotransmitter Release by : Hugo J. Bellen

Download or read book Neurotransmitter Release written by Hugo J. Bellen and published by Oxford University Press, USA. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.

The Hippocampus Book

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Publisher : Oxford University Press
ISBN 13 : 9780195100273
Total Pages : 892 pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis The Hippocampus Book by : Per Andersen

Download or read book The Hippocampus Book written by Per Andersen and published by Oxford University Press. This book was released on 2007 with total page 892 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hippocampus is one of a group of remarkable structures embedded within the brain's medial temporal lobe. Long known to be important for memory, it has been a prime focus of neuroscience research for many years. The Hippocampus Book promises to facilitate developments in the field in a major way by bringing together, for the first time, contributions by leading international scientists knowledgeable about hippocampal anatomy, physiology, and function. This authoritative volume offers the most comprehensive, up-to-date account of what the hippocampus does, how it does it, and what happens when things go wrong. At the same time, it illustrates how research focusing on this single brain structure has revealed principles of wider generality for the whole brain in relation to anatomical connectivity, synaptic plasticity, cognition and behavior, and computational algorithms. Well-organized in its presentation of both theory and experimental data, this peerless work vividly illustrates the astonishing progress that has been made in unraveling the workings of the brain. The Hippocampus Book is destined to take a central place on every neuroscientist's bookshelf.

Synaptic Plasticity in the Hippocampus

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Publisher : Springer Science & Business Media
ISBN 13 : 364273202X
Total Pages : 219 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Synaptic Plasticity in the Hippocampus by : Helmut L. Haas

Download or read book Synaptic Plasticity in the Hippocampus written by Helmut L. Haas and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.

The Book of GENESIS

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Publisher : Springer Verlag
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Book of GENESIS by : James M. Bower

Download or read book The Book of GENESIS written by James M. Bower and published by Springer Verlag. This book was released on 1995 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title introduces and guides the reader through Genesis, a simulation and modeling software tool that is delivered on-line via the Internet from a California Institute of Technology file server. It contains a contribution of models and simulations, plus step-by-step tutorials. 50 illustrations. Approx.

Extrasynaptic GABAA Receptors

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Publisher : Springer
ISBN 13 : 149391426X
Total Pages : 301 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Extrasynaptic GABAA Receptors by : Adam C. Errington

Download or read book Extrasynaptic GABAA Receptors written by Adam C. Errington and published by Springer. This book was released on 2014-09-22 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed “tonic” inhibition, has been described. Whereas synaptic GABAA receptors underlie classical “phasic” GABAA receptor-mediated inhibition (inhibitory postsynaptic currents), tonic GABAA receptor-mediated inhibition results from the activation of extrasynaptic receptors by low concentrations of ambient GABA. Extrasynaptic GABAA receptors are composed of receptor subunits that convey biophysical properties ideally suited to the generation of persistent inhibition and are pharmacologically and functionally distinct from their synaptic counterparts. This book highlights ongoing work examining the properties of recombinant and native extrasynaptic GABAA receptors and their preferential targeting by endogenous and clinically relevant agents. In addition, it emphasizes the important role of extrasynaptic GABAA receptors in GABAergic inhibition throughout the CNS and identifies them as a major player in both physiological and pathophysiological processes.

Handbook of Neurobehavioral Genetics and Phenotyping

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Publisher : John Wiley & Sons
ISBN 13 : 1118540719
Total Pages : 648 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis Handbook of Neurobehavioral Genetics and Phenotyping by : Valter Tucci

Download or read book Handbook of Neurobehavioral Genetics and Phenotyping written by Valter Tucci and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Behavioral Genetics and Phenotyping represents an integrative approach to neurobehavioural genetics; worldwide experts in their field will review all chapters. Advanced overviews of neurobehavioural characteristics will add immense value to the investigation of animal mutants and provide unique information about the genetics and behavioural understanding of animal models, under both normal and pathological conditions. Cross-species comparisons of neurobehavioural phenotypes will pave the way for an evolutionary understanding of behaviour. Moreover, while biological sciences are progressing towards a holistic approach to investigate the complexity of organisms (i.e., “systems biology” approach), an integrated analysis of behavioural phenotyping is still lacking. The Handbook of Behavioral Genetics and Phenotyping strengthens the cross-talk within disciplines that investigate the fundamental basis of behaviour and genetics. This will be the first volume in which traditionally distant fields including genomics, behaviour, electrophysiology, neuroeconomics, and computational neuroscience, among others, are evaluated together and simultaneously accounted for during discussions of future perspectives.

Jasper's Basic Mechanisms of the Epilepsies

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Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Space,Time and Memory in the Hippocampal Formation

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Publisher : Springer
ISBN 13 : 3709112923
Total Pages : 567 pages
Book Rating : 4.7/5 (91 download)

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Book Synopsis Space,Time and Memory in the Hippocampal Formation by : Dori Derdikman

Download or read book Space,Time and Memory in the Hippocampal Formation written by Dori Derdikman and published by Springer. This book was released on 2014-07-08 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of new cell types, such as grid and time cells, in the hippocampus has been accompanied by major anatomical and theoretical insights in the recent years. This book provides comprehensive, up-to-date information about the hippocampal formation and especially the neural basis of episodic memory, spatial location (the formation of the cognitive map) and temporal representation. The first part of the book describes the information flow from pre-hippocampal areas into the hippocampus, the second part discusses the different types of hippocampal processing and finally, the third part depicts the influence that the hippocampal processing has on other brain structures that are perhaps more closely tied to explicit cognitive or behavioral output. This book is intended for neuroscientists, especially for those who are involved in research on the hippocampus, as well as for behavioral scientists and neurologists.

Homeostatic Synaptic Plasticity: From Synaptic Circuit Assembly to Neurological Disorders

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Publisher : Frontiers Media SA
ISBN 13 : 2889669882
Total Pages : 174 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Homeostatic Synaptic Plasticity: From Synaptic Circuit Assembly to Neurological Disorders by : Lorenzo A. Cingolani

Download or read book Homeostatic Synaptic Plasticity: From Synaptic Circuit Assembly to Neurological Disorders written by Lorenzo A. Cingolani and published by Frontiers Media SA. This book was released on 2021-07-08 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Inhibitory Synaptic Plasticity

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Publisher : Springer Science & Business Media
ISBN 13 : 1441969780
Total Pages : 191 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Inhibitory Synaptic Plasticity by : Melanie A. Woodin

Download or read book Inhibitory Synaptic Plasticity written by Melanie A. Woodin and published by Springer Science & Business Media. This book was released on 2010-11-02 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. Inhibitory Synaptic Plasticity will be of particular interest to neuroscientists and neurophysiologists.

Spike-timing dependent plasticity

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Publisher : Frontiers E-books
ISBN 13 : 2889190439
Total Pages : 575 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Spike-timing dependent plasticity by : Henry Markram

Download or read book Spike-timing dependent plasticity written by Henry Markram and published by Frontiers E-books. This book was released on with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hebb's postulate provided a crucial framework to understand synaptic alterations underlying learning and memory. Hebb's theory proposed that neurons that fire together, also wire together, which provided the logical framework for the strengthening of synapses. Weakening of synapses was however addressed by "not being strengthened", and it was only later that the active decrease of synaptic strength was introduced through the discovery of long-term depression caused by low frequency stimulation of the presynaptic neuron. In 1994, it was found that the precise relative timing of pre and postynaptic spikes determined not only the magnitude, but also the direction of synaptic alterations when two neurons are active together. Neurons that fire together may therefore not necessarily wire together if the precise timing of the spikes involved are not tighly correlated. In the subsequent 15 years, Spike Timing Dependent Plasticity (STDP) has been found in multiple brain brain regions and in many different species. The size and shape of the time windows in which positive and negative changes can be made vary for different brain regions, but the core principle of spike timing dependent changes remain. A large number of theoretical studies have also been conducted during this period that explore the computational function of this driving principle and STDP algorithms have become the main learning algorithm when modeling neural networks. This Research Topic will bring together all the key experimental and theoretical research on STDP.

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1860 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1997 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Comprehensive Dissertation Index

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Publisher :
ISBN 13 :
Total Pages : 752 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Comprehensive Dissertation Index by :

Download or read book Comprehensive Dissertation Index written by and published by . This book was released on 1989 with total page 752 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Hippocampal Place Fields

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Publisher : Oxford University Press
ISBN 13 : 0198043457
Total Pages : 431 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis Hippocampal Place Fields by : Sheri J.Y. Mizumori

Download or read book Hippocampal Place Fields written by Sheri J.Y. Mizumori and published by Oxford University Press. This book was released on 2008-02-26 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data from neuropsychological and animal research suggest that the hippocampus plays a pivotal role in two relatively different areas: active navigation, as well as episodic learning and memory. Recent studies have attempted to bridge these disparate accounts of hippocampal function by emphasizing the role that hippocampal place cells may play in processing the spatial contextual information that defines situations in which learned behaviors occur. A number of established laboratories are currently offering complementary interpretations of place fields, and this book will present the first common platform for them. Bringing together research from behavioral, genetic, physiological, computational, and neural-systems perspectives will provide a thorough understanding of the extent to which studying place-field properties has informed our understanding of the neural mechanisms of hippocampus-dependent memory. Hippocampal Place Fields: Relevance to Learning and Memory will serve as a valuable reference for everyone interested in hippocampal function.