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Post Traumatic Epilepsy
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Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2016-04-21 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme
Book Synopsis Post-traumatic Epilepsy by : Marco Mula
Download or read book Post-traumatic Epilepsy written by Marco Mula and published by Cambridge University Press. This book was released on 2021-08-26 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive overview of post-traumatic epilepsy and its management, long-term consequences, and the rehabilitation needs of patients. Covering the neurobiology, epidemiology, and the neuropsychiatric aspects of traumatic brain injuries, special populations such as paediatric patients and athletes with concussive injuries are also discussed.
Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels
Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Book Synopsis The Causes of Epilepsy by : Simon Shorvon
Download or read book The Causes of Epilepsy written by Simon Shorvon and published by Cambridge University Press. This book was released on 2019-05-02 with total page 1013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Expanded and revised, this unique book provides concise descriptions of the many causes of epilepsy, for use in clinical practice.
Book Synopsis Models of Seizures and Epilepsy by : Asla Pitkänen
Download or read book Models of Seizures and Epilepsy written by Asla Pitkänen and published by Academic Press. This book was released on 2017-06-14 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. - Provides a comprehensive reference detailing animal models of epilepsy and seizure - Offers insights on the use of novel technologies that can be applied in experimental epilepsy research - Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques - Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments
Book Synopsis Animal Models of Acute Neurological Injuries by : Jun Chen
Download or read book Animal Models of Acute Neurological Injuries written by Jun Chen and published by Springer Science & Business Media. This book was released on 2008-12-16 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite numerous recent studies and exciting discoveries in the field, only limited treatment is available today for the victims of acute neurological injuries. Animal Models of Acute Neurological Injuries provides a standardized methodology manual designed to eliminate the inconsistent preparations and variability that currently jeopardizes advances in the field. Contributed by top experts and many original developers of the models, each chapter contains a step-by-step, proven procedure and visual aids covering the most commonly used animal models of neurological injury in order to highlight the practical applications of animal models rather than the theoretical issues. This intensive volume presents its readily reproducible protocols with great clarity and consistency to best aid neuroscientists and neurobiologists in laboratory testing and experimentation. Comprehensive and cutting-edge, Animal Models of Acute Neurological Injuries is an ideal guide for scientists and researchers who wish to pursue this vital course of study with the proficiency and precision that the field requires.
Book Synopsis Handbook of Neuroemergency Clinical Trials by : Brett E. Skolnick
Download or read book Handbook of Neuroemergency Clinical Trials written by Brett E. Skolnick and published by Academic Press. This book was released on 2017-11-13 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development. - Presents a comprehensive overview on clinical trials and drug development challenges in acute neuroscience populations - Provides neurologists, neuroscientists and drug developers with a complete understanding of scientific and medical issues related to designing clinical trials - Edited by leaders in the field who have designed and managed over 50 neuroemergency clinical trials
Book Synopsis Astrocytes and Epilepsy by : Jacqueline A. Hubbard
Download or read book Astrocytes and Epilepsy written by Jacqueline A. Hubbard and published by Academic Press. This book was released on 2016-07-05 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. - Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume - Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions - Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation
Book Synopsis Inflammation and Epilepsy: New Vistas by : Damir Janigro
Download or read book Inflammation and Epilepsy: New Vistas written by Damir Janigro and published by Springer Nature. This book was released on 2021-05-18 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
Book Synopsis Traumatic Brain Injury by : Stephen Honeybul
Download or read book Traumatic Brain Injury written by Stephen Honeybul and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive analysis of the contemporary management of all aspects of traumatic brain injury (TBI), combining the findings of several recent randomised controlled trials investigating the role of hypothermia, erythropoietin, intracranial pressure monitoring and decompressive craniectomy in the management of TBI. The book is divided into four sections: the first section covers the epidemiology of TBI, the changing global patterns of presentation, and the basic pathophysiology and classification, while the second discusses contemporary management of TBI, from pre-hospital care, emergency assessment, and medical and surgical management to rehabilitation and social reintegration. The third section then examines the evidence gained from recent clinical trials that have investigated the efficacy of management strategies involving intracranial pressure monitoring, multimodal monitoring, hypothermia, erythropoietin, thromboembolic prophylaxis and decompressive craniectomy. Lastly, the fourth section explores the ethical issues, both at the societal level and on an individual basis. Written by a broad range of experts, this book provides a valuable reference resource for neurosurgeons, intensivists, clinicians with ethical experience and pure bioethicists in their daily work.
Book Synopsis Brain Neurotrauma by : Firas H. Kobeissy
Download or read book Brain Neurotrauma written by Firas H. Kobeissy and published by CRC Press. This book was released on 2015-02-25 with total page 718 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
Download or read book Neurotrauma written by Samer S. Hoz and published by Springer Nature. This book was released on 2022-01-03 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurotrauma in Multiple Choice Questions is the FIRST review book to use the multiple-choice question format in neurosurgical trauma. Students of neurosurgery, the resident, the fellow, the younger neurosurgeon preparing for exams or practice, and even the later stage neurosurgeon are the target audience of this book. The information in this work is in accordance with the most up-to-date best practice evidence, with a style that mirrors the format adopted by the majority of local, regional, and international board examinations. The strategy and format of the questions provide a stepwise progression from definition to surgical decision-making, to a comprehensive and concise overview of neurological trauma.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309486890 Total Pages :211 pages Book Rating :4.3/5 (94 download)
Book Synopsis Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans by : National Academies of Sciences, Engineering, and Medicine
Download or read book Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-05-20 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Veterans Benefits Administration (VBA) provides disability compensation to veterans with a service-connected injury, and to receive disability compensation from the Department of Veterans Affairs (VA), a veteran must submit a claim or have a claim submitted on his or her behalf. Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans reviews the process by which the VA assesses impairments resulting from traumatic brain injury for purposes of awarding disability compensation. This report also provides recommendations for legislative or administrative action for improving the adjudication of veterans' claims seeking entitlement to compensation for all impairments arising from a traumatic brain injury.
Book Synopsis Neurological Diseases and Pregnancy by : Emma Ciafaloni
Download or read book Neurological Diseases and Pregnancy written by Emma Ciafaloni and published by Oxford University Press. This book was released on 2018 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: For a woman of reproductive age, any medical appointment is a pre-conception visit and an opportunity to address pre-existing conditions that affect pregnancy and the maternal-fetal dyad. However, many neurologic conditions are rarely seen in pregnancy, and limited experience and knowledge may prevent the team from developing a shared approach to these complex conditions during pregnancy. Neurological Diseases and Pregnancy: A Coordinated Care Model for Best Management brings together experts across the disciplines of maternal fetal medicine, neurology, obstetrics, family planning, genetics, anesthesia, psychiatry, neurosurgery, and lactation to provide a multi-disciplinary, comprehensive, protocol-driven guide on best care for patients with neurologic disease before, during and after pregnancy. Each chapter provides a detailed care map on each unique disorder, and discusses the use of neurological medications during pregnancy and in lactation. Through this multi-disciplinary approach clinicians can navigate the complexities of preconception and pregnancy care, and help to optimize outcomes for the mother-infant dyad. Beyond pregnancy care, this volume further serves as a resource on best care for the life-course of women affected by neurologic disease including pre-pregnancy planning, genetic counseling, contraception, and sexuality in neurologic disease, as well as post-partum depression and menopausal neurologic changes.
Book Synopsis Neurology and Trauma by : Randolph W. Evans M.D.
Download or read book Neurology and Trauma written by Randolph W. Evans M.D. and published by Oxford University Press. This book was released on 2006-03-16 with total page 823 pages. Available in PDF, EPUB and Kindle. Book excerpt: Disorders due to trauma to the head, spine, and peripheral nerves are among the most common seen by neurologists and neurosurgeons. This 42 chapter book is the comprehensive, definitive work on the subject, offering coverage on a wide range of clinical issues. The second edition features completely new sections on sports and neurologic trauma and iatrogenic trauma to complement existing comprehensive sections on head trauma, spinal trauma, plexus and peripheral nerve injuries, post-traumatic pain syndromes, environmental trauma, and posttraumatic sequelae and medicolegal aspects. Twenty-two of the first edition's chapters have been revised and updated, eight with new coauthors, and 20 new chapters have been added.
Book Synopsis Traumatic Brain and Spinal Cord Injury by : Cristina Morganti-Kossmann
Download or read book Traumatic Brain and Spinal Cord Injury written by Cristina Morganti-Kossmann and published by Cambridge University Press. This book was released on 2012-07-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.
Book Synopsis Neurohospitalist Medicine by : S. Andrew Josephson
Download or read book Neurohospitalist Medicine written by S. Andrew Josephson and published by Cambridge University Press. This book was released on 2011-09-29 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, the hospitalist model has become a dominant system for the delivery of inpatient care. Forces such as national mandates to improve safety and quality, and intense pressure to safely reduce length of hospital stays, are now exerting pressure on neurologists. To meet these challenges, a new neurohospitalist model is emerging. This is the first authoritative text to detail the advances and strategies for treating neurologic disease in a hospital setting. It includes chapters on specific acute neurologic diseases including stroke, epilepsy, neuromuscular disease and traumatic brain injury and also addresses common reasons for neurologic consultation in the hospital including encephalopathy, electrolyte disturbances and neurologic complications of pregnancy. Ethical and structural issues commonly encountered in neurologic inpatients are also addressed. This will be a key resource for any clinician or trainee caring for neurologic patients in the hospital including practising neurologists, internists and trainees across multiple subspecialities.
