Polymer Drugs In The Clinical Stage

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Polymer Drugs in the Clinical Stage

Author : Hiroshi Maeda
Publisher : Springer Science & Business Media
ISBN 13 : 030647932X
Total Pages : 222 pages
Book Rating : 4.3/5 (64 download)

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Book Synopsis Polymer Drugs in the Clinical Stage by : Hiroshi Maeda

Download or read book Polymer Drugs in the Clinical Stage written by Hiroshi Maeda and published by Springer Science & Business Media. This book was released on 2006-04-11 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the International Symposium on Polymer Therapeutics - Recent Progress in Clinics and Future Prospects, held July 13-14, 2001, in Nara, Japan. The technology of polymer science has developed considerably during the past half-century, and this volume describes some of the aspects of this technology that will have a great impact in the future. Among these advances, for example, are gene delivery to specific disease sites and carrier polymers that respond to a stimulus or particular environment. Cancer targeted drug delivery is another focused area of this volume because of the important nature of EPR-effect of polymer drugs in tumor. Included are discussions of as many examples as possible of polymer drugs that have achieved, or are close to clinical use. The concept of "Polymer drugs" here is limited to primarily injectable and water-soluble agents, although also covered are some drugs in micellar form or liposomes. This book is intended for students and researchers in the field of pharmacology who have particular interests in drug delivery, targeting, and formulation, as well as for clinicians such as oncologists who are interested in the field. People who work at regulatory agencies should also be aware such that drugs with great potential are being developed and will be beneficial to many patients, as well as to health insurance agencies because of improved cost effectiveness.

Polymeric Drugs and Drug Delivery Systems

Author : Raphael M. Ottenbrite
Publisher : CRC Press
ISBN 13 : 1420010255
Total Pages : 328 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Polymeric Drugs and Drug Delivery Systems by : Raphael M. Ottenbrite

Download or read book Polymeric Drugs and Drug Delivery Systems written by Raphael M. Ottenbrite and published by CRC Press. This book was released on 2019-04-30 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymeric materials are now playing an increasingly important role in pharmaceuticals, as well as in sensing devices, in situ prostheses and probes, and microparticle diagnostic agents. This new volume consists of twenty-two recent research-based reports on the developments in these areas of pharmaceutical and biomaterials technology. The reports w

Controlled Release of Drugs

Author : Morton Rosoff
Publisher : Wiley-VCH
ISBN 13 :
Total Pages : 336 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Controlled Release of Drugs by : Morton Rosoff

Download or read book Controlled Release of Drugs written by Morton Rosoff and published by Wiley-VCH. This book was released on 1989 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polymers in Medicine

Author : Emo Chiellini
Publisher : CRC Press
ISBN 13 : 9780877629290
Total Pages : 276 pages
Book Rating : 4.6/5 (292 download)

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Book Synopsis Polymers in Medicine by : Emo Chiellini

Download or read book Polymers in Medicine written by Emo Chiellini and published by CRC Press. This book was released on 1992-06-13 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: The utilization of polymers in medicine has become a reality in the last decade. This book is a concise presentation of the fundamentals, applications, and methods of optimization of polymeric drugs and polymeric drug delivery systems for medicinal purposes. The basic rationale for the use of polymeric drugs and polymer delivery systems is the possibility to alter the pharmacokinetics and pharmacodynamics of therapeutic agents so as to maintain an adequate therapeutic environment at the site of disfunction for an extended period of time. The primary objectives for using polymeric drugs and polymeric drug delivery systems are to introduce new and efficient methods of drug administration, to improve efficacy and patient compliance, to decrease toxicity, and to ensure safety. The following factors influence the design and performance of polymers for medicinal applications: disease, drug properties, type of therapy (acute or chronic), physiology of the patient, administration route, and the site requiring therapy.

Polymer-Drug Conjugates

Author : Jitender Madan
Publisher : Elsevier
ISBN 13 : 0323916902
Total Pages : 510 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Polymer-Drug Conjugates by : Jitender Madan

Download or read book Polymer-Drug Conjugates written by Jitender Madan and published by Elsevier. This book was released on 2023-07-05 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymer-Drug Conjugates: Linker Chemistry, Protocols and Applications discusses important concepts, fundamentals and prospective applications of ‘Linker Chemistry’ in a clear-and-concise manner. The book provides vital information on chemical entities binding with the drug-polymer complex for targeted drug delivery systems. It highlights roles and significance, different classes and synthetic protocols as well as mechanisms of chemical bond formation in drug-polymer conjugation in drug delivery, also offering insights into the mechanism of polymer interaction with linker and drug molecules by biodegradable chemical bonding. The protocol of binding with drug molecules is clearly explained and justified with case studies, helping researchers and advanced students in the pharmaceutical sciences understand fundamentals involved and related aspects in molecule designing for effective therapeutic benefits. Covers mechanism, protocol and therapeutic significance of Polymer-Drug Conjugates Outlines updated methods and techniques to enumerate conjugation with related case studies Includes comprehensive compilation of marketed and clinical trial drugs conjugated with polymers or linkers

Polymer Therapeutics II

Author : Ronit Satchi-Fainaro
Publisher : Springer Science & Business Media
ISBN 13 : 9783540292111
Total Pages : 248 pages
Book Rating : 4.2/5 (921 download)

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Book Synopsis Polymer Therapeutics II by : Ronit Satchi-Fainaro

Download or read book Polymer Therapeutics II written by Ronit Satchi-Fainaro and published by Springer Science & Business Media. This book was released on 2006-01-12 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Applications of Polymers in Drug Delivery

Author : Ambikanandan Misra
Publisher : Elsevier
ISBN 13 : 0128226684
Total Pages : 594 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Applications of Polymers in Drug Delivery by : Ambikanandan Misra

Download or read book Applications of Polymers in Drug Delivery written by Ambikanandan Misra and published by Elsevier. This book was released on 2020-10-02 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applications of Polymers in Drug Delivery, Second Edition, provides a comprehensive resource for anyone looking to understand how polymeric materials can be applied to current, new, and emerging drug delivery applications. Polymers play a crucial role in modulating drug delivery and have been fundamental in the successful development of many novel drug delivery systems. This book describes the development of polymeric systems, ranging from conventional dosage forms to the most recent smart systems. Regulatory and intellectual property aspects as well as the clinical applicability of polymeric drug delivery systems are also discussed. The chapters are organized by specific delivery route, offering methodical and detailed coverage throughout. This second edition has been thoroughly revised to include the latest developments in the field. This is an essential book for researchers, scientists, and advanced students, in polymer science, drug delivery, pharmacology/pharmaceuticals, materials science, tissue engineering, nanomedicine, chemistry, and biology. In industry, this book supports scientists, R&D, and other professionals, working on polymers for drug delivery applications. Explains how polymers can be prepared and utilized for all major drug delivery routes Presents the latest advances, including drug targeting, polymeric micelles and polymersomes, and the delivery of biologicals and nucleic acid therapeutics Includes appendices with in-depth information on pharmaceutical properties of polymers and regulatory aspects

Polymeric Drugs

Author : American Chemical Society
Publisher :
ISBN 13 : 9780122207501
Total Pages : 424 pages
Book Rating : 4.2/5 (75 download)

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Book Synopsis Polymeric Drugs by : American Chemical Society

Download or read book Polymeric Drugs written by American Chemical Society and published by . This book was released on 1978 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polymeric Drug Delivery Systems

Author : Glen S. Kwon
Publisher : CRC Press
ISBN 13 : 9780824725327
Total Pages : 680 pages
Book Rating : 4.7/5 (253 download)

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Book Synopsis Polymeric Drug Delivery Systems by : Glen S. Kwon

Download or read book Polymeric Drug Delivery Systems written by Glen S. Kwon and published by CRC Press. This book was released on 2005-04-12 with total page 680 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emphasizing four major classes of polymers for drug delivery-water-soluble polymers, hydrogels, biodegradable polymers, and polymer assemblies-this reference surveys efforts to adapt, modify, and tailor polymers for challenging molecules such as poorly water-soluble compounds, peptides/proteins, and plasmid DNA.

Polymers for Controlled Drug Delivery

Author : Peter J. Tarcha
Publisher : CRC Press
ISBN 13 : 9780849356520
Total Pages : 300 pages
Book Rating : 4.3/5 (565 download)

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Book Synopsis Polymers for Controlled Drug Delivery by : Peter J. Tarcha

Download or read book Polymers for Controlled Drug Delivery written by Peter J. Tarcha and published by CRC Press. This book was released on 1990-11-21 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms. The book primarily discusses classes of polymers and polymeric vehicles, including particulates, such as latexes, coacervates, ion-exchange resins, and liposomes, as well as non-particulate vehicles such as enteric coatings, mediators, and bioadhesives. Other topics discussed include diffusion; biodegradation-controlled delivery; animal model studies for toxicity, metabolism, and elimination testing; and FDA requirements for clinical studies. Drug delivery researchers will find this book to be an invaluable reference tool.

Polymeric Drugs and Drug Administration

Author : Raphael M. Ottenbrite
Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Polymeric Drugs and Drug Administration by : Raphael M. Ottenbrite

Download or read book Polymeric Drugs and Drug Administration written by Raphael M. Ottenbrite and published by . This book was released on 1994 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reviews the role of polymers in the target-specific, controlled- release delivery of drugs in such applications as oncology, inflammation, diabetes, gastric ulcers, and conditions of the central nervous system. Discusses the properties of polymeric materials from the perspective of bioelastic characteristics, micelle formation, hydrogels, electric properties, and degradation. Also considers the theoretical aspects and computer simulations for designing delivery systems. The 19 papers are from a symposium in Washington, D.C. in August 1992. Annotation copyright by Book News, Inc., Portland, OR

Polymers for Drug Delivery in Cancer Therapy

Author : Hong Zi
Publisher :
ISBN 13 :
Total Pages : 88 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Polymers for Drug Delivery in Cancer Therapy by : Hong Zi

Download or read book Polymers for Drug Delivery in Cancer Therapy written by Hong Zi and published by . This book was released on 2008 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polymeric Drugs & Drug Delivery Systems

Author : Raphael M. Ottenbrite
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (134 download)

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Book Synopsis Polymeric Drugs & Drug Delivery Systems by : Raphael M. Ottenbrite

Download or read book Polymeric Drugs & Drug Delivery Systems written by Raphael M. Ottenbrite and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Polymer Therapeutics I

Author : Ronit Satchi-Fainaro
Publisher : Springer Science & Business Media
ISBN 13 :
Total Pages : 224 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Polymer Therapeutics I by : Ronit Satchi-Fainaro

Download or read book Polymer Therapeutics I written by Ronit Satchi-Fainaro and published by Springer Science & Business Media. This book was released on 2006-02-10 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Author : Jorge Coelho
Publisher : Springer Science & Business Media
ISBN 13 : 9400760108
Total Pages : 433 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment by : Jorge Coelho

Download or read book Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment written by Jorge Coelho and published by Springer Science & Business Media. This book was released on 2013-03-15 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM). It focuses on the theme of “Drug delivery systems: advanced technologies potentially applicable in personalised treatments”. The critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, self-assembly, nanotechnology, pharmaceutical formulations, three dimensional structures, molecular modeling, tailor-made solutions and technological tendencies, are carefully discussed. The understanding of these areas constitutes a paramount route to establish personalised and effective solutions for specific diseases and individuals.

PEGylated Protein Drugs: Basic Science and Clinical Applications

Author : Francesco M. Veronese
Publisher : Springer Science & Business Media
ISBN 13 : 3764386797
Total Pages : 289 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis PEGylated Protein Drugs: Basic Science and Clinical Applications by : Francesco M. Veronese

Download or read book PEGylated Protein Drugs: Basic Science and Clinical Applications written by Francesco M. Veronese and published by Springer Science & Business Media. This book was released on 2009-12-30 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: PEGylation technology and key applications are introduced by this topical volume. Basic physical and chemical properties of PEG as basis for altering/improving in vivo behaviour of PEG-conjugates such as increased stability, improved PK/PD, and decreased immunogenicity, are discussed. Furthermore, chemical and enzymatic strategies for the coupling and the conjugate characterization are reported. Following chapters describe approved and marketed PEG-proteins and PEG-oligonucleotides as well as conjugates in various stages of clinical development.

Biodegradable Polymers in Clinical Use and Clinical Development

Author : Abraham J. Domb
Publisher : John Wiley & Sons
ISBN 13 : 1118015800
Total Pages : 594 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Biodegradable Polymers in Clinical Use and Clinical Development by : Abraham J. Domb

Download or read book Biodegradable Polymers in Clinical Use and Clinical Development written by Abraham J. Domb and published by John Wiley & Sons. This book was released on 2011-05-12 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.