Plasticity and Pathology

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Author :
Publisher : Fordham University Press
ISBN 13 : 0823266168
Total Pages : 368 pages
Book Rating : 4.8/5 (232 download)

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Book Synopsis Plasticity and Pathology by : David Bates

Download or read book Plasticity and Pathology written by David Bates and published by Fordham University Press. This book was released on 2016-01-15 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the rise of cognitive science and the revolution in neuroscience, it is now commonplace to assume that the study of a human person—a thinking, feeling, acting subject—is ultimately the study of the human brain. In both Europe and the United States, massive state-funded research is focused on mapping the brain in all its remarkable complexity. The metaphors employed are largely technological: A wiring diagram of synaptic connectivity will lead to a better understanding of human behavior and perhaps insights into the breakdown of human personhood with diseases of the brain such as Alzheimer’s. Alongside this technologized discourse of the brain as locus of human subjectivity we find another perspective, one that emphasizes its essential plasticity—in both the developmental sense and as a response to traumas such as strokes, tumors, or gunshot wounds. This collection of essays brings together a diverse range of scholars to investigate how the “neural subject” of the twenty-first century came to be. Taking approaches both historical and theoretical, they probe the possibilities and limits of neuroscientific understandings of human experience. Topics include landmark studies in the history of neuroscience, the relationship between neural and technological “pathologies,” and analyses of contemporary concepts of plasticity and pathology in cognitive neuroscience. Central to the volume is a critical examination of the relationship between pathology and plasticity. Because pathology is often the occasion for neural reorganization and adaptation, it exists not in opposition to the brain’s “normal” operation but instead as something intimately connected to our ways of being and understanding.

Plasticity and Pathology

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Publisher :
ISBN 13 : 9780823266135
Total Pages : 351 pages
Book Rating : 4.2/5 (661 download)

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Book Synopsis Plasticity and Pathology by : David William Bates

Download or read book Plasticity and Pathology written by David William Bates and published by . This book was released on 2016 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essays collected here were presented at the workshop Plasticity and Pathology: History and Theory of Neural Subjects at the Doreen B. Townsend Center for the Humanities at the University of California, Berkeley.

The Rewiring Brain

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Publisher : Academic Press
ISBN 13 : 0128038721
Total Pages : 592 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis The Rewiring Brain by : Arjen van Ooyen

Download or read book The Rewiring Brain written by Arjen van Ooyen and published by Academic Press. This book was released on 2017-06-23 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. Reviews the current state of knowledge of structural plasticity in the adult brain Gives a comprehensive overview of computational studies on structural plasticity Provides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory Serves as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage

Disorders of Synaptic Plasticity and Schizophrenia

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Publisher : Academic Press
ISBN 13 : 0080548628
Total Pages : 559 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Disorders of Synaptic Plasticity and Schizophrenia by :

Download or read book Disorders of Synaptic Plasticity and Schizophrenia written by and published by Academic Press. This book was released on 2004-05-10 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia is a severe brain disorder that affects 1% of the population. Its cause is due to the interaction of a number of abnormal genes with environmental factors. This book summarizes new advances schizophrenia research that focus on the field of neural and synaptic plasticity. Synapses in the brain in schizophrenia show a wide range of disorders, both structural and functional. This volume covers the most active and promising of these new developments, and opens up new avenues for the treatment of schizophrenia. * Addresses new areas of research in neurotransmitters, receptors, vitamin transport, metabolism, and signaling. * Reviews the growing field of synaptic plasticity research* Provides links with other diseases of the Central Nervous System (CNS)

Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642598978
Total Pages : 191 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic by : Jordan Grafman

Download or read book Neuronal Plasticity: Building a Bridge from the Laboratory to the Clinic written by Jordan Grafman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 191 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last twenty years there has been an explosive growth in our understanding of the molecular, cellular, and anatomical changes that occur in the days and weeks following brain injury. It is now clear that training and exposure to certain environments can modify and shape neuronal plasticity in lower animals and humans. In humans, in particular, there are new ways of charting neuronal plasticity at the ensemble or regional level using functional neuroimaging techniques such as positron emission tomography and functional magnetic resonance imaging. Thus, the time seems right for transporting the laboratory results to the clinic so that experimental findings can be tested in the "field". This volume provides some impetus to moving the field of cognitive neuroscience a little further in its efforts to improve the lives of patients who have suffered a debilitating brain injury.

Catastrophes

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Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3110373777
Total Pages : 207 pages
Book Rating : 4.1/5 (13 download)

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Book Synopsis Catastrophes by : Nitzan Lebovic

Download or read book Catastrophes written by Nitzan Lebovic and published by Walter de Gruyter GmbH & Co KG. This book was released on 2014-07-28 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Catastrophic scenarios dominate our contemporary mindset. Catastrophic events and predictions have spurred new interest in re-examining the history of earlier disasters and the social and conceptual resources they have mobilized. The essays gathered in this volume reconsider the history and theory of different catastrophes and their aftermath. The emphasis is on the need to distance this process of reconsideration from previous teleological representations of catastrophes as an endpoint, and to begin considering their "operative" aspects, which unmask the nature of social and political structures. Among the essays in this volume are analyses, by leading scholars in their respective fields, concerning the role of catastrophes in theology, in the history of industrial accidents, in theory of history, in the history of law, in "catastrophe films", in the history of cybernetics, in post-Holocaust discussions of reparations, and in climate change.

Hormones and Brain Plasticity

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Publisher : Oxford University Press
ISBN 13 : 019532661X
Total Pages : 505 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Hormones and Brain Plasticity by : Luis Miguel Garcia-Segura

Download or read book Hormones and Brain Plasticity written by Luis Miguel Garcia-Segura and published by Oxford University Press. This book was released on 2009-05-05 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proposing that hormones modulate metaplasticity in the brain, the author covers a wide variety of hormones, brain regions, and neuroplastic events, and also provides a new theoretical background with which to interpret the interaction of hormones and brain remodeling throughout the entire life of the organism.--[Source inconnue].

Brain Oscillations, Synchrony and Plasticity

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Author :
Publisher : Academic Press
ISBN 13 : 0128204087
Total Pages : 270 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Brain Oscillations, Synchrony and Plasticity by : Jos J. Eggermont

Download or read book Brain Oscillations, Synchrony and Plasticity written by Jos J. Eggermont and published by Academic Press. This book was released on 2021-01-11 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Oscillations, Synchrony and Plasticity: Basic Principles and Application to Auditory-Related Disorders discusses the role of brain oscillations, especially with respect to the auditory system and how those oscillations are measured, change over the lifespan, and falter leading to a variety of psychiatric and neurological disorders. The book begins with a description of these cortical rhythm oscillations and how they function in both the normal and pathological brain. It explains how these oscillations are important to auditory, executive and attention brain networks and how they relate to the development, production and deterioration of speech and language. In addition, treatment of malfunctioning cortical rhythms are reviewed using neuromodulation, such as transcranial magnetic, direct current, random noise, and alternating current stimulation, as well as focused ultrasound. The book concludes by describing the potential role of oscillations in dyslexia, autism, schizophrenia and Alzheimer’s disease. Introduces readers to brain imaging methods such as structural and functional magnetic resonance imaging, EEG and magnetoencephalography, in the study of brain oscillations, synchrony and networks of the normal and pathological brain Highlights the role of brain oscillations in perception and cognition, in particular with respect to the auditory system, speech and language Describes lifespan changes, from preterm to senescence, of brain oscillations, brain networks and how they relate to the development and deterioration of speech and language Explains the effects of hearing loss on neural network change in the auditory and non-auditory networks such as the default mode-, the salience-, the executive- and attention networks Illustrates the breakdown of network connections in auditory-related disorders such as tinnitus and in psychiatric disorders with a strong auditory, speech and language component

Receptor Dynamics in Neural Development

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Publisher : CRC Press
ISBN 13 : 9780849378171
Total Pages : 370 pages
Book Rating : 4.3/5 (781 download)

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Book Synopsis Receptor Dynamics in Neural Development by : Christopher Ari Shaw

Download or read book Receptor Dynamics in Neural Development written by Christopher Ari Shaw and published by CRC Press. This book was released on 1996-02-13 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive review of what receptors do in the nervous system, how they do it, the mechanisms by which receptor function is regulated, and the consequences of normal and abnormal receptor function. It contains a series of interrelated chapters describing key neurotransmitter receptors, protein kinases, and protein phosphatases, and details their expression and composition in the development of the central nervous system (CNS).

Biomedical Index to PHS-supported Research: pt. A. Subject access A-H

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Publisher :
ISBN 13 :
Total Pages : 1064 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Biomedical Index to PHS-supported Research: pt. A. Subject access A-H by :

Download or read book Biomedical Index to PHS-supported Research: pt. A. Subject access A-H written by and published by . This book was released on 1992 with total page 1064 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genome Plasticity in Health and Disease

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Publisher : Academic Press
ISBN 13 : 0128178205
Total Pages : 290 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Genome Plasticity in Health and Disease by :

Download or read book Genome Plasticity in Health and Disease written by and published by Academic Press. This book was released on 2020-04-08 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors, non-coding RNAs, telomere dynamics and RNA editing. Later chapters explore disease relevance for cancer, as well as cardiovascular, neuropsychiatric, inflammatory, and endocrine disease, and associated pathways for drug discovery. Examines the role of genome plasticity across a range of disease types, from cardiovascular disease, to cancer and neuropsychiatric disorders Adopts an interdisciplinary approach, with expert contributions across the spectrum of basic science and disease relevance to drug discovery

Plasticity in the Somatosensory System of Developing and Mature Mammals — The Effects of Injury to the Central and Peripheral Nervous System

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3642757014
Total Pages : 497 pages
Book Rating : 4.6/5 (427 download)

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Book Synopsis Plasticity in the Somatosensory System of Developing and Mature Mammals — The Effects of Injury to the Central and Peripheral Nervous System by : Peter J. Snow

Download or read book Plasticity in the Somatosensory System of Developing and Mature Mammals — The Effects of Injury to the Central and Peripheral Nervous System written by Peter J. Snow and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rarely have the many mechanisms that might underlie neural plasticity been examined as explicitly as they are in this broad, lavishly illustrated treatment of plasticity in the somatosensory system. The reader is provided with state-of-the-art knowledge of connections at all levels of the somatosensory system. The authors examine the propensity for changes of connectivity in both the mature and developing mammal and make clear proposals regarding the mechanisms underlying these changes. Their functional significance to relevant psychophysical and neurological observations is also discussed.

Translational Research in Traumatic Brain Injury

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Publisher : CRC Press
ISBN 13 : 1498766579
Total Pages : 412 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Translational Research in Traumatic Brain Injury by : Daniel Laskowitz

Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2015-12-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Cognitive Plasticity in Neurologic Disorders

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Publisher : Oxford University Press, USA
ISBN 13 : 0199965242
Total Pages : 433 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis Cognitive Plasticity in Neurologic Disorders by : Joseph I. Tracy

Download or read book Cognitive Plasticity in Neurologic Disorders written by Joseph I. Tracy and published by Oxford University Press, USA. This book was released on 2014-12-02 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume makes clear that the cognitive and behavioural symptoms of neurologic disorders and syndromes are dynamic and changing. Each chapter describes the neuroplastic processes at work in a particular condition, giving rise to these ongoing cognitive changes.

Successful Aging

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Publisher : Penguin
ISBN 13 : 1524744190
Total Pages : 363 pages
Book Rating : 4.5/5 (247 download)

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Book Synopsis Successful Aging by : Daniel J. Levitin

Download or read book Successful Aging written by Daniel J. Levitin and published by Penguin. This book was released on 2020-01-07 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: INSTANT TOP 10 BESTSELLER • New York Times • USA Today • Washington Post • LA Times “Debunks the idea that aging inevitably brings infirmity and unhappiness and instead offers a trove of practical, evidence-based guidance for living longer and better.”—Daniel H. Pink, author of When and Drive SUCCESSFUL AGING delivers powerful insights: • Debunking the myth that memory always declines with age • Confirming that "health span"—not "life span"—is what matters • Proving that sixty-plus years is a unique and newly recognized developmental stage • Recommending that people look forward to joy, as reminiscing doesn't promote health Levitin looks at the science behind what we all can learn from those who age joyously, as well as how to adapt our culture to take full advantage of older people's wisdom and experience. Throughout his exploration of what aging really means, using research from developmental neuroscience and the psychology of individual differences, Levitin reveals resilience strategies and practical, cognitive enhancing tricks everyone should do as they age. Successful Aging inspires a powerful new approach to how readers think about our final decades, and it will revolutionize the way we plan for old age as individuals, family members, and citizens within a society where the average life expectancy continues to rise.

Biomedical Index to PHS-supported Research

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Author :
Publisher :
ISBN 13 :
Total Pages : 1398 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Biomedical Index to PHS-supported Research by :

Download or read book Biomedical Index to PHS-supported Research written by and published by . This book was released on 1987 with total page 1398 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Enabling America

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Publisher : National Academies Press
ISBN 13 : 0309063744
Total Pages : 423 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Enabling America by : Institute of Medicine

Download or read book Enabling America written by Institute of Medicine and published by National Academies Press. This book was released on 1997-11-24 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The most recent high-profile advocate for Americans with disabilities, actor Christopher Reeve, has highlighted for the public the economic and social costs of disability and the importance of rehabilitation. Enabling America is a major analysis of the field of rehabilitation science and engineering. The book explains how to achieve recognition for this evolving field of study, how to set priorities, and how to improve the organization and administration of the numerous federal research programs in this area. The committee introduces the "enabling-disability process" model, which enhances the concepts of disability and rehabilitation, and reviews what is known and what research priorities are emerging in the areas of: Pathology and impairment, including differences between children and adults. Functional limitationsâ€"in a person's ability to eat or walk, for example. Disability as the interaction between a person's pathologies, impairments, and functional limitations and the surrounding physical and social environments. This landmark volume will be of special interest to anyone involved in rehabilitation science and engineering: federal policymakers, rehabilitation practitioners and administrators, researchers, and advocates for persons with disabilities.