Physics at the Biomolecular Interface

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Publisher : Springer
ISBN 13 : 3319308521
Total Pages : 490 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Physics at the Biomolecular Interface by : Ariel Fernández

Download or read book Physics at the Biomolecular Interface written by Ariel Fernández and published by Springer. This book was released on 2016-05-11 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in delineating a solution to the protein folding problem, in unravelling the physico-chemical basis of enzyme catalysis and protein associations, and in rationally designing molecular targeted therapies. Thus grounded in fundamental science, the book develops a powerful technological platform for drug discovery, while it is set to inspire scientists at any level in their careers determined to address the major challenges in molecular biophysics. The acknowledgment of how exquisitely the structure and dynamics of proteins and their aqueous environment are related attests to the overdue recognition that biomolecular phenomena cannot be effectively understood without dealing with interfacial behaviour. There is an urge to grasp how biologically relevant behaviour is shaped by the structuring of biomolecular interfaces and how interfacial tension affects the molecular events that take place in the cell. This book squarely addresses these needs from a physicist perspective. The book may serve as a monograph for practitioners and, alternatively, as an advanced textbook. Fruitful reading requires a background in physical chemistry and some basics in biophysics. The selected problems at the end of the chapters and the progression in conceptual difficulty make it a suitable textbook for a graduate level course or an elective course for seniors majoring in chemistry, physics, biomedical engineering or related disciplines.

Biomolecular Interfaces

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Publisher : Springer
ISBN 13 : 3319168509
Total Pages : 380 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Biomolecular Interfaces by : Ariel Fernández Stigliano

Download or read book Biomolecular Interfaces written by Ariel Fernández Stigliano and published by Springer. This book was released on 2015-04-20 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior. The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.

The Physics of Proteins

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Publisher : Springer Science & Business Media
ISBN 13 : 1441910441
Total Pages : 423 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis The Physics of Proteins by : Hans Frauenfelder

Download or read book The Physics of Proteins written by Hans Frauenfelder and published by Springer Science & Business Media. This book was released on 2010-05-30 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides an introduction to the structure and function of biomolecules --- especially proteins --- and the physical tools used to investigate them The discussion concentrates on physical tools and properties, emphasizing techniques that are contributing to new developments and avoiding those that are already well established and whose results have already been exploited fully New tools appear regularly - synchrotron radiation, proton radiology, holography, optical tweezers, and muon radiography, for example, have all been used to open new areas of understanding

Principles of Cellular Engineering

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Publisher : Elsevier
ISBN 13 : 0080539637
Total Pages : 339 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Principles of Cellular Engineering by : Michael R. King

Download or read book Principles of Cellular Engineering written by Michael R. King and published by Elsevier. This book was released on 2011-04-28 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive work discusses novel biomolecular surfaces that have been engineered to either control or measure cell function at the atomic, molecular, and cellular levels. Each chapter presents real results, concepts, and expert perspectives of how cells interact with biomolecular surfaces, with particular emphasis on interactions within complex mechanical environments such as in the cardiovascular system. In addition, the book provides detailed coverage of inflammation and cellular immune response as a useful model for how engineering concepts and tools may be effectively applied to complex systems in biomedicine. -Accessible to biologists looking for new ways to model their results and engineers interested in biomedical applications -Useful to researchers in biomaterials, inflammation, and vascular biology -Excellent resource for graduate students as a textbook in cell & tissue engineering or cell mechanics courses

Biological Physics at Interfaces : on a Modern Device for Cell Adhesion and Einstein at Single Molecules

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (14 download)

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Book Synopsis Biological Physics at Interfaces : on a Modern Device for Cell Adhesion and Einstein at Single Molecules by : Andreas Hartmann-Ferri

Download or read book Biological Physics at Interfaces : on a Modern Device for Cell Adhesion and Einstein at Single Molecules written by Andreas Hartmann-Ferri and published by . This book was released on 2018 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Physics And Biology: From Molecules To Life

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Publisher : World Scientific
ISBN 13 : 9814616494
Total Pages : 199 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Physics And Biology: From Molecules To Life by : Jean-francois Allemand

Download or read book Physics And Biology: From Molecules To Life written by Jean-francois Allemand and published by World Scientific. This book was released on 2014-10-15 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Do you often lose your keys? You will find in this book the best strategy to find them, or at least the one deduced from statistical physics. What is the link with biology? Some proteins use the same strategy to find their target inside a living cell. This example illustrates one of the many links between physics and biology. These links result from an intense research activity in the past years at the interface between those two disciplines. This book describes some of the most recent progresses at this interface: from instrumental progresses used in biology to the mechanical description of a cell, to molecular motors, from brain activity mechanisms to auditory or sensory perception. Many fields are covered from the molecular to the scale at the organ level. A few biological notions are presented in the first chapter that may help to access the biological aspects of the others. In the end this book may interest people passionate in science, from the simple amateur to the advanced researcher level.

Physics of Bio-Molecules and Cells

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540457011
Total Pages : 591 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Physics of Bio-Molecules and Cells by : Henrik Flyvbjerg

Download or read book Physics of Bio-Molecules and Cells written by Henrik Flyvbjerg and published by Springer Science & Business Media. This book was released on 2003-07-01 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at those working to enter this rapidly developing field, this volume on biological physics is written in a pedagogical style by leading scientists giving explanations that take their starting point where any physicist can follow and end at the frontier of research in biological physics. These lectures describe the state-of-the-art physics of biomolecules and cells. In biological systems ranging from single biomolecules to entire cells and larger biological systems, it focuses on aspects that require concepts and methods from physics for their analysis and understanding, such as the mechanics of motor proteins; how the genetic code is physically read and managed; the machinery of protein--DNA interactions; force spectroscopy of biomolecules' velopes, cytoskeletons, and cytoplasms; polymerization forces; listeria propulsion; cell motility; lab-on-a-chip nanotechnology for single-molecule analysis of biomolecules; bioinformatics; and coding and computational strategies of the brain.

The Physics of Proteins

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Author :
Publisher : Springer
ISBN 13 : 9781441910431
Total Pages : 448 pages
Book Rating : 4.9/5 (14 download)

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Book Synopsis The Physics of Proteins by : Hans Frauenfelder

Download or read book The Physics of Proteins written by Hans Frauenfelder and published by Springer. This book was released on 2010-06-10 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides an introduction to the structure and function of biomolecules --- especially proteins --- and the physical tools used to investigate them The discussion concentrates on physical tools and properties, emphasizing techniques that are contributing to new developments and avoiding those that are already well established and whose results have already been exploited fully New tools appear regularly - synchrotron radiation, proton radiology, holography, optical tweezers, and muon radiography, for example, have all been used to open new areas of understanding

Forces, Growth and Form in Soft Condensed Matter: At the Interface Between Physics and Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402023392
Total Pages : 272 pages
Book Rating : 4.0/5 (233 download)

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Book Synopsis Forces, Growth and Form in Soft Condensed Matter: At the Interface Between Physics and Biology by : Arne Skjeltorp

Download or read book Forces, Growth and Form in Soft Condensed Matter: At the Interface Between Physics and Biology written by Arne Skjeltorp and published by Springer Science & Business Media. This book was released on 2004-08-24 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book reviews the current experimental and theoretical knowledge of the synergism between modern physics, soft condensed matter and biology, presenting a thorough discussion of the relative role of the various fundamental interactions in such systems: electrostatic, hydrophobic, steric, conformational, van der Waals, etc. These competing interactions influence the form and topology of soft and biological matter, like polymers and proteins, leading to hierarchical structures in self-assembling systems and folding patterns sometimes described in terms of chirality, braids and knots. Finally, the competing interactions influence various bioprocesses like genetic regulation and biological evolution taking place in systems like biopolymers, macromolecules and cell membranes. The authors include theoretical physicists, soft condensed matter experimentalists, biological physicists, and molecular biologists - all leaders in their respective fields. Aside from the need to gain new, fundamental insights, the subject area is also of great importance for many applications, in that self-assembly and hierarchical assembly are important features to achieve functionality on multiple length scales. Applications range from the nanoscopic (e.g., biomolecular material and copolymeric mesophases) to the microscopic (all organic microelectronics) to the macroscopic (high-performance structural composites).

Biophysics for Beginners

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Publisher : CRC Press
ISBN 13 : 9814241652
Total Pages : 420 pages
Book Rating : 4.8/5 (142 download)

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Book Synopsis Biophysics for Beginners by : Helmut Schiessel

Download or read book Biophysics for Beginners written by Helmut Schiessel and published by CRC Press. This book was released on 2013-12-20 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysics is a new way of looking at living matter. It uses quantitative experimental and theoretical methods to open a new window for studying and understanding life processes. This textbook gives compact introductions to the basics of the field, including molecular cell biology and statistical physics. It then presents in-depth discussions of more advanced biophysics subjects, progressing to state-of-the-art experiments and their theoretical interpretations. The book is unique by offering a general introduction to biophysics, yet at the same time restricting itself to processes that occur inside the cell nucleus and that involve biopolymers (DNA, RNA, and proteins). This allows for an accessible read for beginners and a springboard for specialists who wish to continue their study in more detail.

Applied Biophysics

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Publisher : John Wiley & Sons
ISBN 13 : 0470513160
Total Pages : 436 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Applied Biophysics by : Thomas Andrew Waigh

Download or read book Applied Biophysics written by Thomas Andrew Waigh and published by John Wiley & Sons. This book was released on 2007-09-27 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the fundamentals of molecular biophysics, and highlights the connection between molecules and biological phenomena, making it an important text across a variety of science disciplines. The topics covered in the book include: Phase transitions that occur in biosystems (protein crystallisation, globule-coil transition etc) Liquid crystallinity as an example of the delicate range of partially ordered phases found with biological molecules How molecules move and propel themselves at the cellular level The general features of self-assembly with examples from proteins The phase behaviour of DNA The physical toolbox presented within this text will form a basis for students to enter into a wide range of pure and applied bioengineering fields in medical, food and pharmaceutical areas.

Integrated Molecular and Cellular Biophysics

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Publisher : Springer Science & Business Media
ISBN 13 : 1402082681
Total Pages : 254 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Integrated Molecular and Cellular Biophysics by : Valerica Raicu

Download or read book Integrated Molecular and Cellular Biophysics written by Valerica Raicu and published by Springer Science & Business Media. This book was released on 2008-06-17 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biophysics represents perhaps one of the best examples of interdisciplinary research areas, where concepts and methods from disciplines such as physics, biology, b- chemistry, colloid chemistry, and physiology are integrated. It is by no means a new ?eld of study and has actually been around, initially as quantitative physiology and partly as colloid science, for over a hundred years. For a long time, biophysics has been taught and practiced as a research discipline mostly in medical schools and life sciences departments, and excellent biophysics textbooks have been published that are targeted at a biologically literate audience. With a few exceptions, it is only relatively recently that biophysics has started to be recognized as a physical science and integrated into physics departments’ curr- ula, sometimes under the new name of biological physics. In this period of cryst- lization and possible rede?nition of biophysics, there still exists some uncertainty as to what biophysics might actually represent. A particular tendency among phy- cists is to associate biophysics research with the development of powerful new te- niques that should eventually be used not by physicists to study physical processes in living matter, but by biologists in their biological investigations. There is value in that judgment, and excellent books have been published that introduce the int- ested reader to the use of physical principles for the development of new methods of investigation in life sciences.

Biological Physics of the Developing Embryo

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Publisher : Cambridge University Press
ISBN 13 : 9780521783378
Total Pages : 346 pages
Book Rating : 4.7/5 (833 download)

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Book Synopsis Biological Physics of the Developing Embryo by : Gabor Forgacs

Download or read book Biological Physics of the Developing Embryo written by Gabor Forgacs and published by Cambridge University Press. This book was released on 2005-11-24 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: During development cells and tissues undergo changes in pattern and form that employ a wider range of physical mechanisms than at any other time in an organism's life. This book demonstrates how physics can be used to analyze these biological phenomena. Written to be accessible to both biologists and physicists, major stages and components of the biological development process are introduced and then analyzed from the viewpoint of physics. The presentation of physical models requires no mathematics beyond basic calculus.

Handbook of Single-Molecule Biophysics

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Publisher : Springer Science & Business Media
ISBN 13 : 0387764976
Total Pages : 634 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Handbook of Single-Molecule Biophysics by : Peter Hinterdorfer

Download or read book Handbook of Single-Molecule Biophysics written by Peter Hinterdorfer and published by Springer Science & Business Media. This book was released on 2009-12-24 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Physics of Molecular and Cellular Processes

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Publisher : Springer Nature
ISBN 13 : 3030986063
Total Pages : 265 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis Physics of Molecular and Cellular Processes by : Krastan B. Blagoev

Download or read book Physics of Molecular and Cellular Processes written by Krastan B. Blagoev and published by Springer Nature. This book was released on 2022-09-08 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a graduate-level introduction to quantitative concepts and methods in the science of living systems. It relies on a systems approach for understanding the physical principles operating in biology. Physical phenomena are treated at the appropriate spatio-temporal scale and phenomenological equations are used in order to reflect the system of interest. Biological details enter to the degree necessary for understanding specific processes, but in many cases the approach is not reductionist. This is in line with the approach taken by physics to many other complex systems. The book bridges the gap between graduate students’ general physics courses and research papers published in professional journals. It gives students the foundations needed for independent research in biological physics and for working in collaborations aimed at quantitative biology and biomedical research. Also included are modern mathematical and theoretical physics methods, giving the student a broad knowledge of tools that can shed light on the sophisticated mechanisms brought forth by evolution in biological systems. The content covers many aspects that have been the focus of active research over the past twenty years, reflecting the authors' experience as leading researchers and teachers in this field.

Molecular and Biological Physics of Living Systems

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Publisher : Springer Science & Business Media
ISBN 13 : 9400918909
Total Pages : 300 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Molecular and Biological Physics of Living Systems by : R.K. Mishra

Download or read book Molecular and Biological Physics of Living Systems written by R.K. Mishra and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The living organisms and systems possess extraordinary properties of programmed development, differentiation, growth, response, movement, duplication of key molecules and in m any cases higher mental functions. But the organisms are physical objects so they must follow laws of physics yet they do not seem to obey them. Physicists cannot easily persuade themselves to accept this as finally true. Non-living objects are governed by these laws of physics and they can explain these properties. However, in the living systems too phenomena encountered like coupled non-linear interactions, manybody effects, cooperativity, coherence, phase transitions, reversible metastable states are being understood better with the aid of powerful theoretical and experimental techniques and hope is raised that these may let us understand the mysteriousness of life. Contributors to this volume are a small fraction of rapidly growing scientific opinion that these aspects of living bodies are to be expected in a hitherto inadequately suspected state of matter which is in the main directed by these physical properties pushed almost to limit. This state of matter, the living matter, deserves to be called The Living State. Mishra proposes that given hydrogenic orbitals, atoms showing easy hybridisability and multiple valances, molecules with low-lying electronic levels, "loosestructure", and a metabolic pump in thermodynamically open system, various fundamental properties of living state can emerge automatically. Structurally these are all known to be present.

Nanobiophysics

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Publisher : CRC Press
ISBN 13 : 9814613975
Total Pages : 428 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Nanobiophysics by : Victor A. Karachevtsev

Download or read book Nanobiophysics written by Victor A. Karachevtsev and published by CRC Press. This book was released on 2016-01-05 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobiophysics is a new branch of science that operates at the interface of physics, biology, chemistry, material science, nanotechnology, and medicine. This book is the first one devoted to nanobiophysics and introduces this field with a focus on some selected topics related to the physics of biomolecular nanosystems, including nucleosomal DNA and