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Physical And Chemical Mechanisms In Molecular Radiation Biology
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Book Synopsis Physical and Chemical Mechanisms in Molecular Radiation Biology by : William A. Glass
Download or read book Physical and Chemical Mechanisms in Molecular Radiation Biology written by William A. Glass and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fundamental understanding of the production of biological effects by ionizing radiation may well be one of the most important scientific objectives of mankind; such understanding could lead to the effective and safe utilization of the nuclear energy option. In addition, this knowledge will be of immense value in such diverse fields as radiation therapy and diagnosis and in the space program. To achieve the above stated objective, the U. S. Department of Energy (DOE) and its predecessors embarked upon a fundamental interdisciplinary research program some 35 years ago. A critical component of this program is the Radiological and Chemical Physics Program (RCPP). When the RCPP was established, there was very little basic knowledge in the fields of physics, chemistry, and biology that could be directly applied to understanding the effects of radiation on biological systems. Progress of the RCPP program in its first 15 years was documented in the proceedings of a conference held at Airlie, Virginia, in 1972. At this conference, it was clear that considerable progr:ess had been made in research on the physical and chemical processes in well-characterized systems that could be used to understand biological effects. During this period of time, most physical knowledge was obtained for the gas phase because the technology and instru mentation had not progressed to the point that measurements could be made in liquids more characteristic of biological materials.
Book Synopsis Physical Mechanisms in Radiation Biology by : Raymond D. Cooper
Download or read book Physical Mechanisms in Radiation Biology written by Raymond D. Cooper and published by . This book was released on 1974 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Physical Processes in Radiation Biology by : Leroy Augenstein
Download or read book Physical Processes in Radiation Biology written by Leroy Augenstein and published by Academic Press. This book was released on 2016-01-22 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Processes in Radiation Biology covers the proceedings of an International Symposium on Physical Processes in Radiation Biology, held at the Kellogg Center for Continuing Education, Michigan State University on May 6-8, 1963, sponsored by the U.S. Atomic Energy Commission. The symposium aims to address the core problems of radiation biology concerning the absorption, distribution, and utilization of high energy packets in biological systems. This book is composed of 21 chapters, and begins with an introduction to the absorption, excitation, and transfer processes in molecular solids. The subsequent chapters discuss the nature of exciton processes; the mechanisms of charge transport in biological materials; the interactions of fast and slow electrons with model systems; the importance of liquid structures in determining the development of radiation damage; and the nature of the metastable species formed. The concluding chapters explore the importance of charge migration in energy transfer processes in different biological systems and the significance of higher excited levels in charge migration and energy transfer. These chapters also describe the nature of the hydration of electrons and protons in aqueous systems. This book will be of great value to radiation biologists, biophysicists, physical chemists, and physicists.
Book Synopsis Advances in Radiation Biology by : John T. Lett
Download or read book Advances in Radiation Biology written by John T. Lett and published by Academic Press. This book was released on 2013-10-22 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 9, provides an overview of the state of knowledge in radiation biology. The book contains nine chapters and begins with a study on the ways in which physical and chemical agents might trigger "regulatory dysfunction" and how these agents might interact with each other. This is followed by separate chapters on the mechanisms underlying changes in vascular function after doses of radiation in the therapeutic range and their role in the development of late effects in normal tissues; the future of hypoxic cell sensitizers in the clinical setting; DNA strand break formation by ionizing radiation; and major pathways which result in radiation-induced loss of cellular proliferative capacity. Subsequent chapters deal with the solid-state radiation chemistry of DNA; radiosensitivity of proliferating mammalian cells; the use of microwave/radiofrequency energy cancer treatment; and the decline of basic radiobiology.
Book Synopsis Advances in Radiation Biology by : Leroy G. Augenstein
Download or read book Advances in Radiation Biology written by Leroy G. Augenstein and published by Academic Press. This book was released on 2013-10-22 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 2, reflects a continuing effort to provide wide-ranging analyses of progress in various phases of radiation research. The articles cover a spectrum of topics varying from the initial physical events which allow us to discriminate color, to the chemical and biological processes which determine the extent and permanence of radiation damage, and finally to the role of genetic control and damage in determining the fate of irradiated cells. The basic emphasis of the articles also varies. In some, the main attempt is to review extensively the available data so as to evaluate the possible contributions of various mechanisms to a given phenomenon. One article is devoted an evaluation of one physical approach which appears to be a promising way of understanding color perception. These different treatments should be of value not only to the researcher but also to the student, inasmuch as each approach is invariably dictated by the state of the art in the area being covered.
Book Synopsis Molecular Radiation Biology by : Hermann Dertinger
Download or read book Molecular Radiation Biology written by Hermann Dertinger and published by Springer Science & Business Media. This book was released on 2013-11-09 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: There can hardly be any doubt that radiation will continue to be an im portant factor in our lives. Present and future advances in atomic tech nology urgently require further work on research and development in the field of radiation biology if the maximum benefit is to be obtained at minimal risk from the various kinds of radiation that form a major by product of nuclear processes. Consequently, it is also necessary to prepare students and younger scientists for doing such work. The present book originates from teaching experience gained in lectures, seminars, and discussion groups started by the undersigned in 1957 and more recently held together with Drs. Dertinger and Jung. The friendly comments given to the German edition made us feel that it might be worth while to put the results of our efforts at the disposal of those to whom English is more familiar. In agreement with the view, based on well-known facts, that most if not aIl of the more striking practical achievements have resulted from patient and careful investigations into some basic problem, the book aims at introducing the reader to the methods of thought and experiment used in molecular radiation biology as weIl as to the results obtained thereby.
Book Synopsis Advances in Radiation Biology by : Leroy G. Augenstein
Download or read book Advances in Radiation Biology written by Leroy G. Augenstein and published by Academic Press. This book was released on 2013-10-22 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Radiation Biology, Volume 1, provides an overview of the state of knowledge in radiation biology. The book contains six chapters and opens with a review some of the recent work bearing on the nature of the radicals produced in water and on the rates of some of the reactions of the radicals. It also comments on some of the applications of the radical model which have been made. These are followed by a chapter on the process of photosynthesis, covering light absorption and emission by pigments, electromagnetic energy transfer among and between pigment molecules, and the (physical) transfer and migration of electronic charge. Subsequent chapters deal with the effects of tritium irradiation on cells; the effects of small doses of ionizing radiation; the radiation chemical reactions of the amino acids; and the nature of temperature effects on enzyme inactivation by various radiations.
Book Synopsis Physical Mechanisms in Radiation Biology by : Raymond D. Cooper
Download or read book Physical Mechanisms in Radiation Biology written by Raymond D. Cooper and published by . This book was released on 1974 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Radiation Biophysics (ionizing Radiations) by : I︠U︡riĭ Borisovich Kudri︠a︡shov
Download or read book Radiation Biophysics (ionizing Radiations) written by I︠U︡riĭ Borisovich Kudri︠a︡shov and published by Nova Publishers. This book was released on 2008 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is concerned with features analysis of radiation damage to living matter at different levels of its organisation, beginning from the molecular level. The general theory of the mechanisms of biological action of radiation based on four logically connected principles of radiation biology is presented for the first time. The book contains abundant material on primary and secondary processes of the response of living systems to radiation, the mechanisms of direct and indirect action of radiation through radiolysis of water and lipids; a detailed consideration of the theory of targets (DNA and biological membranes) and the problems of high- and low-dose irradiation in the context of present-day. The systemic response of the cell to irradiation (oxidative stress, endogenous background radioresistance, damage and repair of biological membranes and DNA, systemic protection against radiation) is approximated. Presentation of these important problems is preceded by an up-to-date evaluation of some aspects regarding dosimetry of ionising radiation.
Book Synopsis Energetics and Mechanisms in Radiation Biology by : Glyn O. Phillips
Download or read book Energetics and Mechanisms in Radiation Biology written by Glyn O. Phillips and published by . This book was released on 1968 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Ionizing Radiation on DNA by : G. Ahnström
Download or read book Effects of Ionizing Radiation on DNA written by G. Ahnström and published by Springer. This book was released on 1978 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Computational Approaches in Molecular Radiation Biology by : Matesh N. Varma
Download or read book Computational Approaches in Molecular Radiation Biology written by Matesh N. Varma and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Office of Health and Environmental Research (OHER) has supported and continues to support development of computational approaches in biology and medicine. OHER's Radiological and Chemical Physics Program initiated development of computational approaches to determine the effects produced by radiation of different quality (such as high energy electrons, protons, helium and other heavy ions, etc. ) in a variety of materials of biological interest-such as water, polymers and DNA; these include molecular excitations and sub-excitations and the production of ionization and their spatial and temporal distribution. In the past several years, significant advances have been made in computational methods for this purpose. In particular, codes based on Monte Carlo techniques have ·been developed that provide a realistic description of track-structure produced by charged particles. In addition, the codes have become sufficiently sophisticated so that it is now possible to calculate the spatial and temporal distribution of energy deposition patterns in small volumes of subnanometer and nanometer dimensions. These dimensions or resolution levels are relevant for our understanding of mechanisms at the molecular level by which radiations affect biological systems. Since the Monte Carlo track structure codes for use in radiation chemistry and radiation biology are still in the developmental stage, a number of investigators have been exploring different strategies for improving these codes.
Book Synopsis Radiation Biophysics by : Edward L. Alpen
Download or read book Radiation Biophysics written by Edward L. Alpen and published by . This book was released on 1990 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition of Radiation Biophysics provides a description of the physics and chemistry of radiation and its effects on biological systems. Coverage begins with fundamental concepts of the physics of radiation and radioactivity, then progresses through the chemistry and biology of the interaction of radiation with living systems.
Book Synopsis Radiation Induced Molecular Phenomena in Nucleic Acids by : Manoj Shukla
Download or read book Radiation Induced Molecular Phenomena in Nucleic Acids written by Manoj Shukla and published by Springer Science & Business Media. This book was released on 2008-05-08 with total page 677 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive theoretical and experimental analysis of UV-radiation and low energy electron induced phenomena in nucleic acid bases (NABs) and base assemblies are presented in this book. NABs are highly photostable; the absorbed energy is dissipated in the form of ultrafast nonradiative decay. This book highlights the possible mechanisms of these phenomena which is important for all living species and discusses technical challenges in exploration of these processes.
Book Synopsis Biological Radiation Effects by : Jürgen Kiefer
Download or read book Biological Radiation Effects written by Jürgen Kiefer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biological action of radiation undoubtedly constitutes an issue of actual con cern, particularly after incidences like those in Harrisburg or Chernobyl. These considerations, however, were not the reason for writing this book although it is hoped that it will also be helpful in this respect. The interaction of radiation with biological systems is such an interesting research objective that to my mind no special justification is needed to pursue these problems. The combination of physics, chemistry and biology presents on one hand a fascinating challenge to the student, on the other, it may lead to insights which are not possible if the dif ferent subjects remain clearly separated. Special problems of radiation biology have quite often led to new approaches in physics (or vice versa), a recent example is "microdosimetry" (chapter 4). Biological radiation a9tion comprises all levels of biological organization. It starts with the absorption in essential atoms and molecules and ends with the development of cancer and genetic hazards to future generations. The structure of the book reflects this. Beginning with physical and chemical fundamentals, it then turns to a description of chemical and subcellular systems. Cellular effects form a large part since they are the basis for understanding all further responses. Reactions of the whole organism, concentrating on mammals and especially humans, are subsequently treated. The book concludes with a short discussion of problems in radiation protection and the application of radiation in medical therapy. These last points are necessarily short and somewhat superficial.
Book Synopsis Radiobiology Textbook by : Sarah Baatout
Download or read book Radiobiology Textbook written by Sarah Baatout and published by Springer Nature. This book was released on 2023-09-23 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook focuses on the various aspects of radiobiology. The goal of radiobiological research is to better understand the effects of radiation exposure at the cellular and molecular levels in order to determine the impact on health. This book offers a unique perspective, by covering not only radiation biology but also radiation physics, radiation oncology, radiotherapy, radiochemistry, radiopharmacy, nuclear medicine, space radiation biology & physics, environmental and human radiation protection, nuclear emergency planning, molecular biology and bioinformatics, as well as the ethical, legal and social considerations related to radiobiology. This range of disciplines contributes to making radiobiology a broad and rather complex topic. This textbook is intended to provide a solid foundation to those interested in the basics and practice of radiobiological science. It is a learning resource, meeting the needs of students, scientists and medical staff with an interest in this rapidly evolving discipline, as well as a teaching tool, with accompanying teaching material to help educators.
Book Synopsis Biomolecular Action of Ionizing Radiation by : Shirley Lehnert
Download or read book Biomolecular Action of Ionizing Radiation written by Shirley Lehnert and published by CRC Press. This book was released on 2007-10-24 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Embracing the transformation of radiation sciences by the recent surge of developments in molecular biology, this progressive text offers an up-to-date analysis of in vitro and in vivo molecular responses in the body induced by ionizing radiation. With a unique emphasis on medical physics applications, Biomolecular Action of Ionizing Radiation also presents a much needed, in-depth perspective on clinical applications for the treatment of cancer and radiation injuries. Based on a popular course given by the author at McGill University,the bookplaces the traditional tenets of radiation biology in the context of contemporary cell and molecular biology. Using terms that non-experts in molecular biology can understand, it clarifies the underlying mechanisms of radiation effects on molecular interactions including signal transduction pathways, modes of cell killing, and non-targeted effects. The author subsequently associates key principles and advances with potential applications, including the use of ionizing radiation as a cytotoxic and cytostatic agent, and radiosensitization by targeting molecular intermediates or signaling molecules involved in radiation-induced processes. Raising the standard for radiation biology texts that are currently available, Biomolecular Action of Ionizing Radiation is an outstanding resource for advanced undergraduate and graduate students in medical physics, radiation oncology, radiation biology, and those who have an interest in the radiation sciences and in cancer treatment.
