Photodynamic Inactivation of Microbial Pathogens

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Publisher : Royal Society of Chemistry
ISBN 13 : 1782626069
Total Pages : 451 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Photodynamic Inactivation of Microbial Pathogens by : Michael R Hamblin

Download or read book Photodynamic Inactivation of Microbial Pathogens written by Michael R Hamblin and published by Royal Society of Chemistry. This book was released on 2015-11-09 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photodynamic therapy (PDT) was discovered over one hundred years ago after observing the death of microorganisms upon exposure to dyes and light. It is the combination of non-toxic dyes and harmless visible light that, in the presence of oxygen, produce highly toxic reactive species. The principal medical application during the last century was in cancer therapy but, in these days of rising antibiotic resistance, PDT shows increasing promise as an alternative approach to treating infections. PDT has also been used in blood product sterilization, peridontology, acne reduction, and the treatment of viral lesions such as those caused by human papilloma virus. It may also have potential as an environmentally friendly pesticide. This is the first and only book to comprehensively cover the use of light and photosensitising agents for controlling microbial pathogens. It provides a comprehensive and up-to-date coverage of an emerging field. There are several chapters on the design of antimicrobial photosensitizers, their use to kill pathogenic organisms and their success in treating infections in animal models. It has long been known that gram-positive bacteria are highly susceptible to photoinactivation but the book also discusses means of widening the range of microorganisms that can be tackled by PDT. Edited by two pioneers in the application of PDT to medical and environmental issues, this book covers the basic science, translational research in animals, and the clinical applications in various medical specialities. It represents an indispensable resource for microbiologists and infectious disease doctors as well as dentists, dermatologists, gastroenterologists and transfusion specialists.

Photodynamic Inactivation of Bacterial Pathogens

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Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (125 download)

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Book Synopsis Photodynamic Inactivation of Bacterial Pathogens by : Peter Walker

Download or read book Photodynamic Inactivation of Bacterial Pathogens written by Peter Walker and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Applications of Porphyrinoids as Functional Materials

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Publisher : Royal Society of Chemistry
ISBN 13 : 1839161884
Total Pages : 463 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Applications of Porphyrinoids as Functional Materials by : Heinrich Lang

Download or read book Applications of Porphyrinoids as Functional Materials written by Heinrich Lang and published by Royal Society of Chemistry. This book was released on 2021-08-18 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of the applications and potential applications of porphyrins and related macrocycles as smart or functional materials.

Aspects of Photodynamic Inactivation of Bacteria

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis Aspects of Photodynamic Inactivation of Bacteria by : Marina Nisnevitch

Download or read book Aspects of Photodynamic Inactivation of Bacteria written by Marina Nisnevitch and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasing resistance of bacteria to antibiotics is a serious worldwide problem, and to combat resistant bacteria, new antibacterial approaches are to be developed. One alternative to traditional antibiotic therapy is photodynamic antimicrobial chemotherapy (PACT). PACT is based on excitation of photosensitizers (PS) capable of transferring the absorbed light energy to dissolved molecular oxygen causing generation of reactive oxygen species, which irreversibly damage bacterial cell components. The overall efficiency of PACT has been proven for Gram-positive and Gram-negative bacteria. The effectiveness of PACT can be increased by encapsulation of PS in liposomes providing more concentrated delivery of PS, enhanced cytotoxicity, improved pharmacokinetic properties, sustained release, and prolonged action of the PS. For continuous and reusable application, PS can be immobilized in polymers. Chemiluminescence, sonodynamic treatment, and radiofrequency irradiation allow to perform excitation of PS in the dark without external illumination, opening prospects for combating internal infections. Combination of PS with antibiotics can gain a synergistic effect, allowing in some cases to overcome the resistance of bacteria to antibiotics.

Development of Novel Photosensitizers for Photodynamic Inactivation of Bacteria

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Author :
Publisher :
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.:/5 (781 download)

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Book Synopsis Development of Novel Photosensitizers for Photodynamic Inactivation of Bacteria by : Elke Feese

Download or read book Development of Novel Photosensitizers for Photodynamic Inactivation of Bacteria written by Elke Feese and published by . This book was released on 2011 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Redox-Active Therapeutics

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Publisher : Springer
ISBN 13 : 3319307053
Total Pages : 709 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Redox-Active Therapeutics by : Ines Batinić-Haberle

Download or read book Redox-Active Therapeutics written by Ines Batinić-Haberle and published by Springer. This book was released on 2016-10-13 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.

Science and Technology Against Microbial Pathogens

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Publisher : World Scientific
ISBN 13 : 9814354864
Total Pages : 447 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Science and Technology Against Microbial Pathogens by : A. Méndez-Vilas

Download or read book Science and Technology Against Microbial Pathogens written by A. Méndez-Vilas and published by World Scientific. This book was released on 2011 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antimicrobial susceptibility profile and effect of stem bark extracts of Curtisia dentata on multi-drug resistant verotoxic Escherichia coli and Acinetobacter spp. isolates obtained from water and wastewater samples / Hamuel James Doughari [und weitere]. Antimicrobial utilization in intensive care units of a private tertiary care hospital / Pramil Tiwari, Vani Yadav and Shilpi Singh. Bacterial clearance from blood in mice infected by S. pneumoniae (penicillin MIC = 16 ug/ml) presenting specific IgG (non-protective levels) and treated with sub-therapeutic regimens of cefditoren (a highly bound cephalosporin) / Fabio Cafini [und weitere]. Characterisation of methicillin resistant Staphylococcus aureus isolates from hospitalised patients / Vladimir Kmet, Daniela Ohlasova and Milan Niks. Characterization of methicillin-resistant coagulase-negative Staphylococci isolates from blood cultures in a Brazilian University Hospital / Valeria Cataneli Pereira and Maria de Lourdes Ribeiro de Souza da Cunha. Control of bacterial contamination in boar semen doses / J.M. Morrell and Margareta Wallgren. Diffusion of extended-spectrum B-lactamase producing Enterobacter cloacae in a kidney transplantation unit / S. Hammami [und weitere]. Effect of antifungal agents on non-Candida albicans Candida species enzymatic activity / M. Negri [und weitere]. Effect of chitosan, nisin and storage time on the growth of Listeria innocua and Shewanella putrefaciens in fish homogenates / L.I. Schelegueda, M.F. Gliemmo and C.A. Campos. ESBL-producing Enterobacteriaceae in the northern Portugal - antimicrobial susceptibility and molecular epidemiology / R. Fernandes and C. Prudencio. Observations on the antimicrobial susceptibility of Staphylococcus pseudintermedius following the introduction of cefovecin for clinical use in Europe / Y. Chaudhry, A. Robinson and K.S. Godinho. Oxacillin resistance among Staphylococcus aureus isolated from peritoneal dialysis related peritonitis / C.H. Camargo [und weitere]. Resistance detection and susceptibility profile in Staphylococcus spp. isolated from patients with urinary tract infection (UTI) / Adriano Martison Ferreira [und weitere]. Resistance distribution profile of MBL, ESBL and multidrug resistant Gram negatives isolated at a tertiary care hospital in India / K.H. Bhutada and V.R. Shende

Nanostructures for Antimicrobial Therapy

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Author :
Publisher : Elsevier
ISBN 13 : 0323461514
Total Pages : 724 pages
Book Rating : 4.3/5 (234 download)

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Book Synopsis Nanostructures for Antimicrobial Therapy by : Anton Ficai

Download or read book Nanostructures for Antimicrobial Therapy written by Anton Ficai and published by Elsevier. This book was released on 2017-05-29 with total page 724 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Porphycenes in Photodynamic Therapy of Cancer Cells and Photodynamic Inactivation of Bacteria

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (114 download)

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Book Synopsis Porphycenes in Photodynamic Therapy of Cancer Cells and Photodynamic Inactivation of Bacteria by : Natalia Masiera

Download or read book Porphycenes in Photodynamic Therapy of Cancer Cells and Photodynamic Inactivation of Bacteria written by Natalia Masiera and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Photosensitizers

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Publisher :
ISBN 13 : 9781536101850
Total Pages : pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Photosensitizers by :

Download or read book Photosensitizers written by and published by . This book was released on 2016-12-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Multiple Action-Based Design Approaches to Antibacterials

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Author :
Publisher : Springer Nature
ISBN 13 : 9811609993
Total Pages : 193 pages
Book Rating : 4.8/5 (116 download)

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Book Synopsis Multiple Action-Based Design Approaches to Antibacterials by : John Bremner

Download or read book Multiple Action-Based Design Approaches to Antibacterials written by John Bremner and published by Springer Nature. This book was released on 2021-04-05 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers intentional design aspects for combinations of drugs, single-molecule hybrids with potential or actual multiple actions, pro-drugs which could yield multiple activity outcomes, and future possibilities. The approach of the book is interdisciplinary, and it provides greater understanding of the complex interplay of factors involved in the medicinal chemistry design and laboratory development of multiply active antibacterials. The scope of the book appeals to readers who are researching in the field of antibacterials using the approach of medicinal chemistry design and drug development.

The Science of Phototherapy: An Introduction

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402028830
Total Pages : 404 pages
Book Rating : 4.0/5 (288 download)

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Book Synopsis The Science of Phototherapy: An Introduction by : Leonard I. Grossweiner

Download or read book The Science of Phototherapy: An Introduction written by Leonard I. Grossweiner and published by Springer Science & Business Media. This book was released on 2005-01-27 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume emphasizes the science underlying the various phototherapy procedures, which encompasses aspects of classical and molecular photophysics, biological photochemistry, photobiology and biophotonics. Suitable as an introductory reference or textbook.

Photodynamic Inactivation

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Publisher :
ISBN 13 :
Total Pages : 362 pages
Book Rating : 4.:/5 (773 download)

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Book Synopsis Photodynamic Inactivation by : Hi-mui Tang

Download or read book Photodynamic Inactivation written by Hi-mui Tang and published by . This book was released on 2009 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Antimocrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes

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Author :
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1681740559
Total Pages : 106 pages
Book Rating : 4.6/5 (817 download)

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Book Synopsis Antimocrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes by : Lucas F de Freitas

Download or read book Antimocrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes written by Lucas F de Freitas and published by Morgan & Claypool Publishers. This book was released on 2016-04-01 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed and current information on using fullerenes (bucky-balls) in photodynamic therapy (PDT), one of the most actively studied applications of photonic science in healthcare. This will serve as a useful source for researchers working in photomedicine and nanomedicine, especially those who are investigating PDT for cancer treatment and infectious disease treatment. The book runs the gamut from an introduction to the history and chemistry of fullerenes and some basic photochemistry, to the application of fullerenes as photosensitizers for cancer and antimicrobial inactivation.

Bioinorganic Photochemistry

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Publisher : John Wiley & Sons
ISBN 13 : 9781405193276
Total Pages : 398 pages
Book Rating : 4.1/5 (932 download)

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Book Synopsis Bioinorganic Photochemistry by : Grazyna Stochel

Download or read book Bioinorganic Photochemistry written by Grazyna Stochel and published by John Wiley & Sons. This book was released on 2009-06-10 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioinorganic photochemistry is a rapidly evolving field integrating inorganic photochemistry with biological, medical and environmental sciences. The interactions of light with inorganic species in natural systems, and the applications in artificial systems of medical or environmental importance, form the basis of this challenging inter-disciplinary research area. Bioinorganic Photochemistry provides a comprehensive overview of the concepts and reactions fundamental to the field, illustrating important applications in biological, medical and environmental sciences. Topics covered include: Cosmic and environmental photochemistry Photochemistry of biologically relevant nanoassemblies Molecular aspects of photosynthesis Photoinduced electron transfer in biosystems Modern therapeutic strategies in photomedicine The book concludes with an outlook for the future of environmental protection, discussing emerging techniques in the field of pollution abatement, and the potential for bioinorganic photochemistry as a pathway to developing cheap, environmentally friendly sources of energy. Written as an authoritative guide for researchers involved in the development of bioinorganic photochemical processes, Bioinorganic Photochemistry is also accessible to scientists new to the field, and will be a key reference source for advanced courses in inorganic, and bioinorganic chemistry.

Oral Biofilms

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068527
Total Pages : 247 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Oral Biofilms by : S. Eick

Download or read book Oral Biofilms written by S. Eick and published by Karger Medical and Scientific Publishers. This book was released on 2020-12-21 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofilms are highly organized polymicrobial communities that are embedded in an extracellular matrix and formed on natural and artificial surfaces. In the oral cavity, biofilms are formed not only on natural teeth, but also on restorative materials, prosthetic constructions, and dental implants. Oral diseases like caries, gingivitis, periodontitis, and also pulp inflammation are associated with biofilms. This publication is an up-to-date overview on oral biofilms from different clinically relevant perspectives. Experts comprising basic researchers and clinicians report on recent research relating to biofilms - from general summaries to recommendations for daily clinical work. This book covers all aspects of oral biofilms, including models used in the laboratory, biofilms in dental water unit lines, periodontal and peri-implant biofilms, caries-related biofilms, halitosis, endodontic biofilms, and Candida infections, as well as biofilms on dental materials and on orthodontic appliances. Several chapters deal with anti-biofilm therapy, from the efficacy of mechanical methods and the use of antimicrobials, to alternative concepts. This publication is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on biofilms.

Antimicrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes

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Author :
Publisher : Myprint
ISBN 13 : 9781681747392
Total Pages : 88 pages
Book Rating : 4.7/5 (473 download)

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Book Synopsis Antimicrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes by : L F de Freitas

Download or read book Antimicrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes written by L F de Freitas and published by Myprint. This book was released on 2016-04-14 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: