Redox Active Therapeutics

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Redox-Active Therapeutics

Author : Ines Batinić-Haberle
Publisher : Springer
ISBN 13 : 3319307053
Total Pages : 694 pages
Book Rating : 4.3/5 (193 download)

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Book Synopsis Redox-Active Therapeutics by : Ines Batinić-Haberle

Download or read book Redox-Active Therapeutics written by Ines Batinić-Haberle and published by Springer. This book was released on 2016-10-13 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. Subsequent sections and chapters describe more specialized aspects of central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis). It encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and most notably metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer’s Oxidative Stress in Applied Basic Research and Clinical Practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome—the organism redox network—as an emerging frontier in drug design, redox biology and medicine.

Oxidative Stress and Antioxidant Protection

Author : Donald Armstrong
Publisher : John Wiley & Sons
ISBN 13 : 1118832485
Total Pages : 610 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Oxidative Stress and Antioxidant Protection by : Donald Armstrong

Download or read book Oxidative Stress and Antioxidant Protection written by Donald Armstrong and published by John Wiley & Sons. This book was released on 2016-04-11 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

Organoselenium Compounds in Biology and Medicine

Author : Vimal Kumar Jain
Publisher : Royal Society of Chemistry
ISBN 13 : 1788010299
Total Pages : 457 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Organoselenium Compounds in Biology and Medicine by : Vimal Kumar Jain

Download or read book Organoselenium Compounds in Biology and Medicine written by Vimal Kumar Jain and published by Royal Society of Chemistry. This book was released on 2017-10-03 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.

Uses of Inorganic Chemistry in Medicine

Author : Nicholas Farrell
Publisher : Royal Society of Chemistry
ISBN 13 : 9780854044443
Total Pages : 180 pages
Book Rating : 4.0/5 (444 download)

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Book Synopsis Uses of Inorganic Chemistry in Medicine by : Nicholas Farrell

Download or read book Uses of Inorganic Chemistry in Medicine written by Nicholas Farrell and published by Royal Society of Chemistry. This book was released on 1999 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will be an invaluable asset for many in the discipline.

Peptide And Protein Engineering For Biotechnological And Therapeutic Applications

Author : Pierre Rousselot-pailley
Publisher : World Scientific
ISBN 13 : 9811261679
Total Pages : 520 pages
Book Rating : 4.8/5 (112 download)

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Book Synopsis Peptide And Protein Engineering For Biotechnological And Therapeutic Applications by : Pierre Rousselot-pailley

Download or read book Peptide And Protein Engineering For Biotechnological And Therapeutic Applications written by Pierre Rousselot-pailley and published by World Scientific. This book was released on 2023-01-06 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peptides and proteins are crucial biomolecules in life. The manifold functions they carry out range from molecular recognition and signaling to catalysis and immune response. However, the native systems are limited to a reduced toolbox of chemical functionalities as well as tridimensional structures. Widening these toolboxes could pave the way to engineer peptides and proteins with enhanced properties compared to their native counterparts and/or with structures and functions unprecedented in Nature. Advances in the chemical and biological synthesis of peptides and proteins, in computational tools, in molecular biology and in high-throughput screening methods are making this realm possible.This book aims to give an overview of the last developments in the field of peptide and protein engineering. It comprises a collection of chapters that span from the production of simple non-proteinogenic building blocks and peptidic scaffolds of different sizes and structures to more complex systems including peptide-based nanomaterials, enzymes and artificial metalloenzymes. Different strategies are described where chemical and biological tools have been developed and combined to attain the desired properties and sought functionalities.The diverse systems described in this book highlight the progress in this important field and represent the starting points for the development of functional biomolecules, biomaterials and hybrid systems capable of addressing key societal challenges of our times in relevant areas such health, environment and energy.

Improving the Therapeutic Ratio in Head and Neck Cancer

Author :
Publisher : Academic Press
ISBN 13 : 0128178698
Total Pages : 376 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Improving the Therapeutic Ratio in Head and Neck Cancer by :

Download or read book Improving the Therapeutic Ratio in Head and Neck Cancer written by and published by Academic Press. This book was released on 2019-10-04 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites. Provides key scientific background for clinicians when developing novel clinical trials and important examples for basic scientists of the types of work required to move a concept from the lab to the clinic Presents consistent pathway diagrams in each chapter, thus making it easier to understand complicated pathways Includes chapter summaries of the critical next steps needed to move studies from their current state into practice changing clinical data

Redox-Active Molecules as Antimicrobials: Mechanisms and Resistance

Author : Martin C. H. Gruhlke
Publisher : Frontiers Media SA
ISBN 13 : 2889716376
Total Pages : 72 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Redox-Active Molecules as Antimicrobials: Mechanisms and Resistance by : Martin C. H. Gruhlke

Download or read book Redox-Active Molecules as Antimicrobials: Mechanisms and Resistance written by Martin C. H. Gruhlke and published by Frontiers Media SA. This book was released on 2021-11-15 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Antioxidant Methodology

Author : Paul D. Prenzler
Publisher : Royal Society of Chemistry
ISBN 13 : 1839161558
Total Pages : 537 pages
Book Rating : 4.8/5 (391 download)

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Book Synopsis Handbook of Antioxidant Methodology by : Paul D. Prenzler

Download or read book Handbook of Antioxidant Methodology written by Paul D. Prenzler and published by Royal Society of Chemistry. This book was released on 2021-10-20 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing a number of the controversies on antioxidant testing methods, this book provides guidance on what methods are most appropriate for different situations, how results are interpreted and what can be inferred from the data.

DNA Repair in Cancer Therapy

Author : Mark R. Kelley
Publisher : Academic Press
ISBN 13 : 0123849993
Total Pages : 341 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis DNA Repair in Cancer Therapy by : Mark R. Kelley

Download or read book DNA Repair in Cancer Therapy written by Mark R. Kelley and published by Academic Press. This book was released on 2011-09-12 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mark R. Kelley

Oxidative Stress Revisited - Major Role in Vascular Diseases

Author : Cristina M. Sena
Publisher : Frontiers Media SA
ISBN 13 : 2889630587
Total Pages : 158 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Oxidative Stress Revisited - Major Role in Vascular Diseases by : Cristina M. Sena

Download or read book Oxidative Stress Revisited - Major Role in Vascular Diseases written by Cristina M. Sena and published by Frontiers Media SA. This book was released on 2019-10-21 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress is an underlying factor in health and disease. Reactive oxygen species are produced as a result of normal cellular metabolism. The subsequent altered redox state between the formation and the neutralization of pro-oxidants results in their increased levels and therefore leads to cellular damage. Different research disciplines have increased our knowledge of the importance of this cell redox status and the recognition of oxidative stress as a process with implications for many pathophysiological states. Genetic and environmental factors, nutrition and lifestyle may indicate a pro-oxidative and pro-inflammatory state, linked to alterations in cellular structure and function. Oxidative stress emerges as a common, unifying factor in several conditions including diabetes and cardiovascular diseases. This eBook aims to provide novel data regarding the role played by oxidative stress and inflammation in the development of chronic diseases and the different classes of therapeutics from the bench to the clinic, stressing the awareness of these concepts for the treatment of disease. In addition, articles addressing an overview of the role of oxidative stress in vascular diseases reviewing some current concepts indicating that oxidative stress and inflammation are key mechanisms linking vascular diseases and current state-of-the-art approaches to monitor, prevent and inhibit oxidative stress will be highlighted. There is a close relation between oxidative stress, inflammation and cardiovascular diseases. Despite the great amount of investigation carried out in the field, there are still uncertainties about the mechanisms by which free radicals can modify tissues such as perivascular adipose tissue that ultimately will reflect on vascular function. This eBook will focus on articles that can explore and identify these mechanisms. Concurrent with this understanding of oxidative stress milieu, it is necessary to recognize the need for new pharmacological tools effective in restoring oxidative balance. The abundance of new information and the paradigm shift in our understanding of how antioxidants and other redox-active drugs work in a wide variety of vascular diseases will be specifically highlighted. This eBook will provide a comprehensive, up-to-date source of information on the design and mechanistic, pharmacological, and medicinal aspects of redox-active therapeutics. Finally, a unique feature of the eBook is to provide a way to foster an enthralling discussion revisiting old paradigms and finding new solutions for the treatment of vascular diseases. The topic will include original research articles, hypotheses, perspectives and (mini)reviews from experts in the field. The next decade shows promise for the translation of this body of knowledge to novel human therapeutics and this eBook will enable to increment our knowledge in this field.

Metal-based Anticancer Agents

Author : Angela Casini
Publisher : Royal Society of Chemistry
ISBN 13 : 1788017676
Total Pages : 370 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Metal-based Anticancer Agents by : Angela Casini

Download or read book Metal-based Anticancer Agents written by Angela Casini and published by Royal Society of Chemistry. This book was released on 2019-04-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal-based anticancer drugs are among the most successful therapeutic agents, as evidenced by the frequent prescription of selected platinum and arsenic compounds to patients. Metal-based Anticancer Agents covers the interdisciplinary world of inorganic drug discovery and development by introducing the most prominent compound classes based on different transition metals, discussing emerging concepts and enabling methods, as well as presenting key pre-clinical and clinical aspects. Recent progress on the unique features of next-generation targeted metal-based anticancer agents, including supramolecular coordination complexes used for both therapy and drug delivery, promise a bright future beyond the benefits of pure cytotoxic activity. With contributions from global leaders in the field, this book will serve as a useful reference to established researchers as well as a practical guide to those new to metallodrugs, and postgraduate students of medicinal chemistry and metallobiology.

Aromatic Amino Acids—Advances in Research and Treatment: 2012 Edition

Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464992274
Total Pages : 556 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Aromatic Amino Acids—Advances in Research and Treatment: 2012 Edition by :

Download or read book Aromatic Amino Acids—Advances in Research and Treatment: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aromatic Amino Acids—Advances in Research and Treatment: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Aromatic Amino Acids. The editors have built Aromatic Amino Acids—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Aromatic Amino Acids in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Aromatic Amino Acids—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Herbal Medicine in Andrology

Author : Ralf Henkel
Publisher : Academic Press
ISBN 13 : 0128155663
Total Pages : 264 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Herbal Medicine in Andrology by : Ralf Henkel

Download or read book Herbal Medicine in Andrology written by Ralf Henkel and published by Academic Press. This book was released on 2020-11-13 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Herbal Medicine in Andrology: An Evidence-Based Update provides a comprehensive overview of ethnomedical approaches in andrology, including ethnopharmacology of plant extracts and relevant bioactive compounds. It highlights information on the availability of medicinal plants and the legal and procedural processes involved in developing a marketable product. This reference helps clinicians and scientists develop an understanding on how herbal medicine can be used to treat andrological patients in practice. Only a limited number of journal articles are available on this topic, making this reference a valuable source of information for a large audience, including urologists, andrologists, gynecologists, reproductive endocrinologists and basic scientists. Provides essential evidence-based information about herbal medicine Offers an ethnopharmacological background on bioactive compounds in certain plant extracts Educates the basic scientist and clinician on the use of herbal medicines in andrology Provides an update to recent advances on herbal medicine in andrology from world experts

Comprehensive Clinical Plasma Medicine

Author : Hans-Robert Metelmann
Publisher : Springer
ISBN 13 : 331967627X
Total Pages : 526 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Comprehensive Clinical Plasma Medicine by : Hans-Robert Metelmann

Download or read book Comprehensive Clinical Plasma Medicine written by Hans-Robert Metelmann and published by Springer. This book was released on 2018-05-04 with total page 526 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the state of the art in clinical plasma medicine and outlines translational research strategies. Written by an international group of authors, it is divided into four parts. Part I is a detailed introduction and includes basic and recent research information on plasma sciences, plasma devices and mechanisms of biological plasma effects. Parts II and III provide valuable clinical insights f.e. into the treatment of superficial contaminations, ulcerations, wounds, treatment of cells in cancer, special indications like in heart surgery, dentistry, palliative treatment in head and neck cancer or the use of plasma in hygiene. Part IV offers information on how and where to qualify in plasma medicine and which companies produce and supply medical devices and is thus of particular interest to medical practitioners. This comprehensive book offers a sciences based practical to the clinical use of plasma and includes an extended selection of scientific medical data and translational literature.

Nutrition in the Prevention and Treatment of Disease

Author : Ann M. Coulston
Publisher : Academic Press
ISBN 13 : 0080569609
Total Pages : 912 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Nutrition in the Prevention and Treatment of Disease by : Ann M. Coulston

Download or read book Nutrition in the Prevention and Treatment of Disease written by Ann M. Coulston and published by Academic Press. This book was released on 2008-05-12 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nutrition in the Prevention and Treatment of Disease, Second Edition, focuses on the clinical applications and disease prevention of nutrition. This revised edition offers 18 completely new chapters and 50% overall material updated. Foundation chapters on nutrition research methodology and application clearly link the contributions of basic science to applied nutrition research and, in turn, to research-based patient care guidelines. Readers will learn to integrate basic principles and concepts across disciplines and areas of research and practice as well as how to apply this knowledge in new creative ways. Chapters on specific nutrients and health cover topics where data are just beginning to be identified, such as choline, antioxidants, nutrition and cognition, and eye disease. Established areas of chronic disease: obesity, diabetes, cardiovascular disease, gastrointestinal disease, and bone health are presented each in their own sections, which aim to demonstrate the inter-action of basic science, genetics, applied nutrition research, and research-based patient care guidelines. Given its unique focus and extensive coverage of clinical applications and disease prevention, this edition is organized for easy integration into advanced upper-division or graduate nutrition curriculums. Busy researchers and clinicians can use this book as a "referesher course" and should feel confident in making patient care recommendations based on solid current research findings. * 18 completely new chapters and 50% overall new material * Unique focus and extensive coverage of clinical applications and disease prevention. * Clearly links the contributions of basic science to applied nutrition research and, in turn, to research-based patient care guidelines. * Assimilates a large body of research and applications and serves as a “refresher course for busy researchers and clinicians.

Redox-Active Molecules as Therapeutic Agents

Author : Ana Sofia Fernandes
Publisher : Mdpi AG
ISBN 13 : 9783036543819
Total Pages : 0 pages
Book Rating : 4.5/5 (438 download)

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Book Synopsis Redox-Active Molecules as Therapeutic Agents by : Ana Sofia Fernandes

Download or read book Redox-Active Molecules as Therapeutic Agents written by Ana Sofia Fernandes and published by Mdpi AG. This book was released on 2022-06-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of research by providing novel mechanistic insights. This book compiles a collection of 13 articles, covering a range of topics from in vitro studies to clinical research, focused on the potential therapeutic effects of either natural or synthetic compounds, applicable to different redox-related diseases.

Microbial Oxidative Enzymes

Author : Arti Gupta
Publisher : Walter de Gruyter GmbH & Co KG
ISBN 13 : 3111062236
Total Pages : 530 pages
Book Rating : 4.1/5 (11 download)

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Book Synopsis Microbial Oxidative Enzymes by : Arti Gupta

Download or read book Microbial Oxidative Enzymes written by Arti Gupta and published by Walter de Gruyter GmbH & Co KG. This book was released on 2023-12-31 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial oxidative enzymes are in need of today and in the future also. Several microbial oxidative enzymes are being used by various sectors like food, agriculture, medicine, detergents, leather, paper, etc. Microbial oxidative enzymes are a natural product, hence, the application of these enzymes is eco-friendly. Oxidative enzymes from microbes like bacteria, and fungi will be helpful in numerous applications including plant-soil health management, and waste treatments. This book will be more informative as well as useful for related industries and end users and will be of great value to those interested in present-day research on oxidation-reduction enzymes. In the coming years, this book will be a game changer for the field of oxidative enzyme development and its applications.