Phosphate Labeling and Sensing in Chemical Biology

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Publisher : Springer
ISBN 13 : 3319603574
Total Pages : 242 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Phosphate Labeling and Sensing in Chemical Biology by : Henning Jacob Jessen

Download or read book Phosphate Labeling and Sensing in Chemical Biology written by Henning Jacob Jessen and published by Springer. This book was released on 2017-07-08 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.

Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine

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Publisher : Springer Science & Business Media
ISBN 13 : 9781402017704
Total Pages : 424 pages
Book Rating : 4.0/5 (177 download)

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Book Synopsis Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine by : Manfred P. Schneider

Download or read book Chemical Probes in Biology Science at the Interface of Chemistry, Biology and Medicine written by Manfred P. Schneider and published by Springer Science & Business Media. This book was released on 2003-11-30 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of Bio-organic Chemistry or Chemical Biology, as it it also called, constitutes a highly interdisciplinary branch of chemistry, beyond the traditional pathways in which chemists and biologists have been working in the past. The topics covered in this book include inter alia: anticancer agents, antioxidants, chemotaxis, carbohydrates, DNA detection and delivery, enzyme structure, enzyme assisted syntheses, fluorescent probes, gene therapy, genomics, inositol phospholipids, inositol phosphates, multivalent ligands, organic syntheses, oxidative stress, photoaffinity labeling techniques, natural products - syntheses and biological activities, phospholipases, proteomics, receptors such as tyrosine kinases, signal transduction phenomena, x-ray crystallography and many more. The book represents an excellent survey of the current stete of the art in an exciting area of interdisciplinary science and supplies an incentive for increased cooperation in Science at the Interface of Chemistry, Biology and Medicine.

Biochemistry of Lipids, Lipoproteins and Membranes

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Publisher : Elsevier
ISBN 13 : 0323983286
Total Pages : 738 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Biochemistry of Lipids, Lipoproteins and Membranes by : Neale Ridgway

Download or read book Biochemistry of Lipids, Lipoproteins and Membranes written by Neale Ridgway and published by Elsevier. This book was released on 2021-08-19 with total page 738 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences. As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis. - Fully revised to cover new and emerging topics - Provides an important bridge between broad-based biochemistry research and application - Presents key concepts that are supported by figures and models to improve understanding - Includes references from current literature in each chapter to facilitate in-depth study

Chemical and Biological Sensors 11 -and- MEMS/NEMS 11

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Publisher : The Electrochemical Society
ISBN 13 : 160768537X
Total Pages : 262 pages
Book Rating : 4.6/5 (76 download)

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Book Synopsis Chemical and Biological Sensors 11 -and- MEMS/NEMS 11 by : Z. Aguilar

Download or read book Chemical and Biological Sensors 11 -and- MEMS/NEMS 11 written by Z. Aguilar and published by The Electrochemical Society. This book was released on 2014 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nonradioactive Labeling and Detection of Biomolecules

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Publisher : Springer
ISBN 13 : 3662001446
Total Pages : 449 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Nonradioactive Labeling and Detection of Biomolecules by : Christoph Kessler

Download or read book Nonradioactive Labeling and Detection of Biomolecules written by Christoph Kessler and published by Springer. This book was released on 2012-12-06 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: All the bioanalytical labeling and detection techniques in one source! This book gathers together all the important nonradioactive labeling techniques for nucleic acids, proteins, glycoproteins and glycolipids like Digoxigenin:Anti-Dioxigenin (DIG), Biotin, 5-Bromodeoxyuridine (BrdU), Sulfone, Immunogold, Silver Enhancement, and Synthetic Nucleic Acid Probe (SNAP) as well as the standard procedures for optical, chemical, biological, electrochemiluminescent and fluorescent detection. Additionally, applications for the use of non-isotopically labeled biomolecules are described. Specific protocols are given for hybridization analysis such as blot, colony/plaque and in-situ hybridization formats, quantitative formats, and also nonradioactivetechniques for nucleic acid sequencing and amplification. Each chapter contains a short introduction, a detailed description of the method with labprotocols, troubleshooting tips and references.

Fluorescent Dye Labels and Stains

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Publisher : John Wiley & Sons
ISBN 13 : 1119835151
Total Pages : 500 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Fluorescent Dye Labels and Stains by : Tarso B. Ledur Kist

Download or read book Fluorescent Dye Labels and Stains written by Tarso B. Ledur Kist and published by John Wiley & Sons. This book was released on 2023-03-10 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescent Dye Labels and Stains The only comprehensive database of fluorophores and their physical and photochemical properties Fluorophores are chemical compounds that strongly absorb in the ultraviolet, visible, and/or near-infrared and with bright emission in these ranges. As a result, they are exceptionally valuable as dyes for various analytical processes, capable of labelling and staining particular targets for purposes of fluorescent imaging, sensitive detection, and quantification (exhibiting linear responses over very wide concentration ranges). These compounds are many and varied, and panoramic views of their options, physical properties and their reactions to light excitations can be critical to their successful integration into chemical analysis, pharmaceutical analysis, clinical analysis, microscopies, optical bioimaging, cancer imaging, real-time PCR, flow cytometry, multiplexing in proteomics, life sciences in general, and many other high-tech fields (material sciences, traceability, photovoltaics, quantum computing). Fluorescent Dye Labels and Stains incorporates a comprehensive database of such substances and their characteristics. It provides an introduction to basic theories and foundational terminology, in addition to both the molecular structures and photophysical properties of an enormous range of fluorophores. Assembled over the course of a distinguished career in biochemistry, this database presents valuable information that has never before been available in a single volume. Readers will also find: Molecular and photochemical information of over 700 fluorophores A database of parameters, including light excitation ranges, molar absorption coefficients, fluorescence quantum yields, molecular brightness, and many more Information derived from multiple disciplines, including microscopy, nanoscopy, biochemistry, and molecular biology Fluorescent Dye Labels and Stains is the essential reference for pharmaceutical and biomedical researchers and professionals, academics who study molecular biology or organic chemistry, and any professional whose work includes strong and photostable molecular absorptions and fluorescence.

Chemical Biology of Glycoproteins

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Publisher : Royal Society of Chemistry
ISBN 13 : 1788011228
Total Pages : 334 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Chemical Biology of Glycoproteins by : Zhongping Tan

Download or read book Chemical Biology of Glycoproteins written by Zhongping Tan and published by Royal Society of Chemistry. This book was released on 2017-03-20 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions. Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.

Chemical Biology-Based Probes For The Labeling Of Targets On Live Cells

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (944 download)

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Book Synopsis Chemical Biology-Based Probes For The Labeling Of Targets On Live Cells by : Amanda M. Hussey

Download or read book Chemical Biology-Based Probes For The Labeling Of Targets On Live Cells written by Amanda M. Hussey and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Proper detection is the key to studying any processes on the cellular scale. Nowhere is this more evident than in the tight space which confines the synaptic cleft. Being able to ascertain the location of receptors on live neurons is fundamental to our understanding of not only how these receptors interact and move inside the cell but also how neurons function. Most detection methods rely on significantly altering the receptor; both tagging with a fluorescent protein or targeting the receptor by a fluorescent reporter in the form of a small molecule causes significant difficulties. These localization techniques often result in forced dimerization, unnatural movement, and at worst inactivation of the receptor. Small molecule organic dyes provide a potential advantage because they can be structurally functionalized to target the protein of interest in a non-perturbing fashion which allows for information to be gathered about the targeted receptor. The work I initiated in the Chambers lab first focused on using a ligand directed fluorophore connected via a photo-labile linker. Through the use of epifluorescence microscopy, I determined that this probe targets glutamate receptors, however questions about subtype inclusion could not be addressed The pharmacophore that our first probe is based on could be much more promiscuous than is presently appreciated in the field of neurobiology. Thus, we designed a new series of probes to allow for covalent modification and affinity purification of endogenous receptors. The second generation of probes set out to answer the questions left by the first. Purified proteins were subjected to SDS-PAGE analysis and could be applied to proteomic identification of receptors. In addition to ligand directed probes, we have also initiated a project on a new, bimolecular photoaffinity probe in which the new methodology continues to develop. The initial studies were performed to ensure that our new strategy is able to be used in biological systems.

Non-Radioactive Labelling

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Publisher : Elsevier
ISBN 13 : 0080551092
Total Pages : 155 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Non-Radioactive Labelling by : A. J. Garman

Download or read book Non-Radioactive Labelling written by A. J. Garman and published by Elsevier. This book was released on 1997-03-20 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological Techniques is a series of volumes aimed at introducing to a wide audience the latest advances in methodology. The pitfalls and problems of new techniques are given due consideration, as are those small but vital details not always explicit in the methods sections of journal papers.In recent years, most biological laboratories have been invaded by computers and a wealth of new DNA technology and this will be reflected in many of the titles appearing in the series.The books will be of value to advanced researchers and graduate students seeking to learn and apply new techniques, and will be useful to teachers of advanced undergraduate courses involving practical or project work.Labelled biomolecules are an essential tool in life science research, and non-radioactive labels are becoming increasingly important due to their convenience of measurement, greater safety and lack of disposal problems compared to radioactive labels.This book provides practical information, background theory and protocols to allow a beginner to label many types of biomolecules, including proteins, peptides, nucleic acids and small molecules.This book is essential for biochemists, molecular biologists and cell biologists wanting to use non-radioactively labelled molecules.Aimed at researchers without specific expertise in chemistry, the book includes: - A review of the main signal systems and labels available, indicating their strengths and weaknesses - Discussion of the most useful strategies for labelling the various biomolecules - 32 protocols covering common labelling needs - Descriptions of the factors governing protocol design, enabling protocols to be modified for different applications - Sources of information including references, data and suppliers

Challenges and Innovations in Ocean In Situ Sensors

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Publisher : Elsevier
ISBN 13 : 0128098872
Total Pages : 410 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Challenges and Innovations in Ocean In Situ Sensors by : Eric Delory

Download or read book Challenges and Innovations in Ocean In Situ Sensors written by Eric Delory and published by Elsevier. This book was released on 2018-09-21 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Challenges and Innovations in Ocean In-Situ Sensors: Measuring Inner Ocean Processes and Health in the Digital Age highlights collaborations of industry and academia in identifying the key challenges and solutions related to ocean observations. A new generation of sensors is presented that addresses the need for higher reliability (e.g. against biofouling), better integration on platforms in terms of size and communication, and data flow across domains (in-situ, space, etc.). Several developments are showcased using a broad diversity of measuring techniques and technologies. Chapters address different sensors and approaches for measurements, including applications, quality monitoring and initiatives that will guide the need for monitoring. Integrates information across key marine and maritime sectors and supports regional policy requirements on monitoring programs Offers tactics for enabling early detection and more effective monitoring of the marine environment and implementation of appropriate management actions Presents new technologies driving the next generation of sensors, allowing readers to understand new capabilities for monitoring and opportunities for another generation of sensors Includes a global vision for ocean monitoring that fosters a new perspective on the direction of ocean measurements

Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods

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Publisher : Academic Press
ISBN 13 : 0128211555
Total Pages : 528 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods by :

Download or read book Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods written by and published by Academic Press. This book was released on 2020-07-24 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods, Volume 641 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include caged cyclopropanes with improved tetrazine ligation kinetics, an analysis of metabolically labeled inositol phosphate messengers by NMR, cell-permeant caged inositol pyrophosphates for probing ß-cells, imaging phospholipase D activity with clickable alcohols via transphosphatidylation, fluorescent biorthogonal labeling of class B GPCRs in live cells, near-infrared photoactivatable nitric oxide donors with integrated photoacoustic monitoring, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on retinoid signaling pathways

New Methods and Sensors for Membrane and Cell Volume Research

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Publisher : Academic Press
ISBN 13 : 0323911153
Total Pages : 428 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis New Methods and Sensors for Membrane and Cell Volume Research by :

Download or read book New Methods and Sensors for Membrane and Cell Volume Research written by and published by Academic Press. This book was released on 2021-12-01 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Methods and Sensors for Membrane and Cell Volume Research, Volume 88 provides an overview of novel experimental approaches to study both the cell membrane and the under-membrane space – the cytosol, which have lately began drawing renewed attention. The book's overall emphasis is on fluorescent and FRET-based sensors, however, other optical (such as variants of transmission microscopy) and non-optical methods (neutron scattering and mass spectrometry) also have dedicated chapters. This volume provides a rare review of experimental approaches to study intracellular phase transitions, as well as anion channels, membrane tension and dynamics, and other topics of intense current interest. - Describes novel FRET-based membrane sensors - Reviews selected non-optical approaches to membrane structure and dynamics - Describes traditional and modern aspects of cell volume research, such as phase transitions and macromolecular crowding

Chemical Sensors 8

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Publisher : The Electrochemical Society
ISBN 13 : 1566776570
Total Pages : 592 pages
Book Rating : 4.5/5 (667 download)

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Book Synopsis Chemical Sensors 8 by : R. Mukundan

Download or read book Chemical Sensors 8 written by R. Mukundan and published by The Electrochemical Society. This book was released on 2008 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This ECS Transactions issue is a compilation of papers presented at the PRiME 2008 Joint International Meeting, held in Hawaii from October 12 - October 17, 2008. The papers presented covered the research and development in the field of chemical (gas, ion, bio and other) sensors, including molecular recognition surface, transduction methods, and integrated and micro sensor systems.

Ferritins—Advances in Research and Application: 2012 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1481638939
Total Pages : 19 pages
Book Rating : 4.4/5 (816 download)

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Book Synopsis Ferritins—Advances in Research and Application: 2012 Edition by :

Download or read book Ferritins—Advances in Research and Application: 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ferritins—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Ferritins in a compact format. The editors have built Ferritins—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Ferritins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Ferritins—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Security of Industrial Water Supply and Management

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Publisher : Springer Science & Business Media
ISBN 13 : 9400718675
Total Pages : 261 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Security of Industrial Water Supply and Management by : Aysel T. Atimtay

Download or read book Security of Industrial Water Supply and Management written by Aysel T. Atimtay and published by Springer Science & Business Media. This book was released on 2011-08-24 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over time, the increased use of fresh water for agriculture and industry together with contamination from discharges of pollutants, mean that ever more areas of the planet are becoming water-stressed. Because of the competing needs of communities and industry for fresh water, industry will be challenged to meet its growing demands for water, which is essential for producing the goods and services that would boost human welfare. Thus industry will need to learn how to cost-effectively purify and recycle its wastewater for reuse, ultimately approaching a net zero-discharge condition. The chapters in this book, written by international experts, treat the technical issues of such treatment and water management, and also provide guidance on technologies, either existing or in development, that can potentially achieve the goal of recycle-reuse. The book will serve as a useful reference for academics, government and industry professionals alike.

Technological Innovations in Sensing and Detection of Chemical, Biological, Radiological, Nuclear Threats and Ecological Terrorism

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Publisher : Springer Science & Business Media
ISBN 13 : 940072487X
Total Pages : 396 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Technological Innovations in Sensing and Detection of Chemical, Biological, Radiological, Nuclear Threats and Ecological Terrorism by : Ashok Vaseashta

Download or read book Technological Innovations in Sensing and Detection of Chemical, Biological, Radiological, Nuclear Threats and Ecological Terrorism written by Ashok Vaseashta and published by Springer Science & Business Media. This book was released on 2012-01-05 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book arises from the NATO Advanced Study Institute “Technological Innovations in Detection and Sensing of CBRN Agents and Ecological Terrorism” held in Chisinau, Republic of Moldova in June 2010. It comprises a variety of invited contributions by highly experienced educators, scientists, and industrialists, and is structured to cover important aspects of the field that include developments in chemical-biological, and radiation sensing, synthesis and processing of sensors, and applications of sensors in detecting/monitoring contaminants introduced/dispersed inadvertently or intentionally in air, water, and food supplies. The book emphasizes nanomaterials and nanotechnology based sensing and also includes a section on sensing and detection technologies that can be applied to information security. Finally, it examines regional, national, and international policies and ethics related to nanomaterials and sensing. It will be of considerable interest and value to those already pursuing or considering careers in the field of nanostructured materials and nanotechnology based sensing, In general, it serves as a valuable source of information for those interested in how nanomaterials and nanotechnologies are advancing the field of sensing, detection, and remediation, policy makers, and commanders in the field.

Chemical and Biological Sensors and Analytical Methods II

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Author :
Publisher : The Electrochemical Society
ISBN 13 : 9781566773515
Total Pages : 706 pages
Book Rating : 4.7/5 (735 download)

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Book Synopsis Chemical and Biological Sensors and Analytical Methods II by : Electrochemical Society. Sensor Division

Download or read book Chemical and Biological Sensors and Analytical Methods II written by Electrochemical Society. Sensor Division and published by The Electrochemical Society. This book was released on 2001 with total page 706 pages. Available in PDF, EPUB and Kindle. Book excerpt: