Bioanalytics

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Bioanalytics

Author : Friedrich Lottspeich
Publisher : John Wiley & Sons
ISBN 13 : 3527694447
Total Pages : 450 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Bioanalytics by : Friedrich Lottspeich

Download or read book Bioanalytics written by Friedrich Lottspeich and published by John Wiley & Sons. This book was released on 2018-03-08 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analytical methods are the essential enabling tools of the modern biosciences. This book presents a comprehensive introduction into these analytical methods, including their physical and chemical backgrounds, as well as a discussion of the strengths and weakness of each method. It covers all major techniques for the determination and experimental analysis of biological macromolecules, including proteins, carbohydrates, lipids and nucleic acids. The presentation includes frequent cross-references in order to highlight the many connections between different techniques. The book provides a bird's eye view of the entire subject and enables the reader to select the most appropriate method for any given bioanalytical challenge. This makes the book a handy resource for students and researchers in setting up and evaluating experimental research. The depth of the analysis and the comprehensive nature of the coverage mean that there is also a great deal of new material, even for experienced experimentalists. The following techniques are covered in detail: - Purification and determination of proteins - Measuring enzymatic activity - Microcalorimetry - Immunoassays, affinity chromatography and other immunological methods - Cross-linking, cleavage, and chemical modification of proteins - Light microscopy, electron microscopy and atomic force microscopy - Chromatographic and electrophoretic techniques - Protein sequence and composition analysis - Mass spectrometry methods - Measuring protein-protein interactions - Biosensors - NMR and EPR of biomolecules - Electron microscopy and X-ray structure analysis - Carbohydrate and lipid analysis - Analysis of posttranslational modifications - Isolation and determination of nucleic acids - DNA hybridization techniques - Polymerase chain reaction techniques - Protein sequence and composition analysis - DNA sequence and epigenetic modification analysis - Analysis of protein-nucleic acid interactions - Analysis of sequence data - Proteomics, metabolomics, peptidomics and toponomics - Chemical biology

Handbook of Bioanalytics

Author : Bogusław Buszewski
Publisher : Springer Nature
ISBN 13 : 3030956601
Total Pages : 1091 pages
Book Rating : 4.0/5 (39 download)

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Book Synopsis Handbook of Bioanalytics by : Bogusław Buszewski

Download or read book Handbook of Bioanalytics written by Bogusław Buszewski and published by Springer Nature. This book was released on 2022-06-30 with total page 1091 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.

Optical Nano- and Microsystems for Bioanalytics

Author : Wolfgang Fritzsche
Publisher : Springer Science & Business Media
ISBN 13 : 3642254977
Total Pages : 332 pages
Book Rating : 4.6/5 (422 download)

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Book Synopsis Optical Nano- and Microsystems for Bioanalytics by : Wolfgang Fritzsche

Download or read book Optical Nano- and Microsystems for Bioanalytics written by Wolfgang Fritzsche and published by Springer Science & Business Media. This book was released on 2012-02-04 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the state of the art in the field of bioanalytical nano- and microsystems with optical functionality. In 12 chapters distinguished scientists and leaders in their respective fields show how various optical technologies have been miniaturized and integrated over the last few decades in order to be combined with nano- and microsystems for applications in the life sciences. The main detection and characterization technologies are introduced, and examples of the superiority of these integrated approaches compared to traditional ones are provided. Examples from e.g. the fields of optical waveguides, integrated interferometers, surface plasmon resonance or Raman spectroscopy are introduced and discussed, and it is shown how these approaches have led to novel functionalities and thereby novel applications.

Handbook of Bioanalytics

Author : Bogusław Buszewski
Publisher : Springer
ISBN 13 : 9783030956592
Total Pages : 0 pages
Book Rating : 4.9/5 (565 download)

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Book Synopsis Handbook of Bioanalytics by : Bogusław Buszewski

Download or read book Handbook of Bioanalytics written by Bogusław Buszewski and published by Springer. This book was released on 2022-07-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an authoritative review of analytical methods used for diagnostics, medical therapy and for forensic purposes. Divided into 4 parts, the book discusses new challenges in bioanalytics, covers bioanalysis as a source of clinical, pharmaceutical and forensic information, explores natural resources as a source of biologically active compounds, and offers new analytical strategies and equipment solutions. Written by interdisciplinary expert academics, this work will appeal to a wide readership of students, researchers and professionals interested in the fields of medicine, chemistry, pharmaceutical, life and health sciences, engineering and environmental protection. Clinicians and employees of forensic laboratories will also find this work instructive and informative.

Handbook of LC-MS Bioanalysis

Author : Wenkui Li
Publisher : John Wiley & Sons
ISBN 13 : 111867135X
Total Pages : 709 pages
Book Rating : 4.1/5 (186 download)

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Book Synopsis Handbook of LC-MS Bioanalysis by : Wenkui Li

Download or read book Handbook of LC-MS Bioanalysis written by Wenkui Li and published by John Wiley & Sons. This book was released on 2013-09-03 with total page 709 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consolidates the information LC-MS bioanalytical scientists need to analyze small molecules and macromolecules The field of bioanalysis has advanced rapidly, propelled by new approaches for developing bioanalytical methods, new liquid chromatographic (LC) techniques, and new mass spectrometric (MS) instruments. Moreover, there are a host of guidelines and regulations designed to ensure the quality of bioanalytical results. Presenting the best practices, experimental protocols, and the latest understanding of regulations, this book offers a comprehensive review of LC-MS bioanalysis of small molecules and macromolecules. It not only addresses the needs of bioanalytical scientists working on routine projects, but also explores advanced and emerging technologies such as high-resolution mass spectrometry and dried blood spot microsampling. Handbook of LC-MS Bioanalysis features contributions from an international team of leading bioanalytical scientists. Their contributions reflect a review of the latest findings, practices, and regulations as well as their own firsthand analytical laboratory experience. The book thoroughly examines: Fundamentals of LC-MS bioanalysis in drug discovery, drug development, and therapeutic drug monitoring The current understanding of regulations governing LC-MS bioanalysis Best practices and detailed technical instructions for LC-MS bioanalysis method development, validation, and stability assessment of analyte(s) of interest Experimental guidelines and protocols for quantitative LC-MS bioanalysis of challenging molecules, including pro-drugs, acyl glucuronides, N-oxides, reactive compounds, and photosensitive and autooxidative compounds With its focus on current bioanalytical practice, Handbook of LC-MS Bioanalysis enables bioanalytical scientists to develop and validate robust LC-MS assay methods, all in compliance with current regulations and standards.

Regulated Bioanalysis: Fundamentals and Practice

Author : Mario L. Rocci Jr.
Publisher : Springer
ISBN 13 : 3319548026
Total Pages : 230 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Regulated Bioanalysis: Fundamentals and Practice by : Mario L. Rocci Jr.

Download or read book Regulated Bioanalysis: Fundamentals and Practice written by Mario L. Rocci Jr. and published by Springer. This book was released on 2017-04-24 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: The editors have engaged leading scientists in the field to participate in the development of this book, which is envisioned as a “one of a kind” contribution to the field. The book is a comprehensive text that puts fundamental bioanalytical science in context with current practice, its challenges and ongoing developments. It expands on existing texts on the subject by covering regulated bioanalysis of both small and large molecule therapeutics from both a scientific and regulatory viewpoint. The content will be useful to a wide spectrum of readers: from those new to bioanalysis; to those developing their experience in the laboratory, or working in one of the many critical supporting roles; to seasoned practitioners looking for a solid source of information on this exciting and important discipline.

Biomolecular and Bioanalytical Techniques

Author : Vasudevan Ramesh
Publisher : John Wiley & Sons
ISBN 13 : 1119483964
Total Pages : 576 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Biomolecular and Bioanalytical Techniques by : Vasudevan Ramesh

Download or read book Biomolecular and Bioanalytical Techniques written by Vasudevan Ramesh and published by John Wiley & Sons. This book was released on 2019-06-10 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential guide to biomolecular and bioanalytical techniques and their applications Biomolecular and Bioanalytical Techniques offers an introduction to, and a basic understanding of, a wide range of biophysical techniques. The text takes an interdisciplinary approach with contributions from a panel of distinguished experts. With a focus on research, the text comprehensively covers a broad selection of topics drawn from contemporary research in the fields of chemistry and biology. Each of the internationally reputed authors has contributed a single chapter on a specific technique. The chapters cover the specific technique’s background, theory, principles, technique, methodology, protocol and applications. The text explores the use of a variety of analytical tools to characterise biological samples. The contributors explain how to identify and quantify biochemically important molecules, including small molecules as well as biological macromolecules such as enzymes, antibodies, proteins, peptides and nucleic acids. This book is filled with essential knowledge and explores the skills needed to carry out the research and development roles in academic and industrial laboratories. A technique-focused book that bridges the gap between an introductory text and a book on advanced research methods Provides the necessary background and skills needed to advance the research methods Features a structured approach within each chapter Demonstrates an interdisciplinary approach that serves to develop independent thinking Written for students in chemistry, biological, medical, pharmaceutical, forensic and biophysical sciences, Biomolecular and Bioanalytical Techniques is an in-depth review of the most current biomolecular and bioanalytical techniques in the field.

Tools and Trends in Bioanalytical Chemistry

Author : Lauro Tatsuo Kubota
Publisher : Springer Nature
ISBN 13 : 3030823814
Total Pages : 559 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Tools and Trends in Bioanalytical Chemistry by : Lauro Tatsuo Kubota

Download or read book Tools and Trends in Bioanalytical Chemistry written by Lauro Tatsuo Kubota and published by Springer Nature. This book was released on 2021-11-25 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook covers the main tools and techniques used in bioanalysis, provides an overview of their principles, and offers several examples of their application and future trends in diagnosis. Chapters from expert contributors explore the role of bioanalysis in different areas such as biochemistry, physiology, forensics, and clinical diagnosis, including topics from sampling/sample preparation, chemometrics in bioanalysis to the latest techniques used in the field. Particular attention is given to the recent advances in the application of mass spectrometry, NMR, electrochemical methods and separation techniques in bioanalysis. Readers will also find more about the application of microchip-based devices and analytical microarrays. This textbook will appeal to graduate/advanced undergraduate students in Chemistry, Biology, Biochemistry, Pharmacy, and Chemical Engineering. It is also a useful resource for researchers and professionals working in the fields of biomedicine and veterinary sciences, with clear explanations and examples of how the different bioanalytical devices are applied for clinical diagnosis.

Bioanalytical Techniques

Author : Abhilasha Shourie
Publisher : The Energy and Resources Institute (TERI)
ISBN 13 : 8179935299
Total Pages : 424 pages
Book Rating : 4.1/5 (799 download)

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Book Synopsis Bioanalytical Techniques by : Abhilasha Shourie

Download or read book Bioanalytical Techniques written by Abhilasha Shourie and published by The Energy and Resources Institute (TERI). This book was released on 2005-01-01 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioanalytical Techniques form an integral part of applied biology and biomedical sciences. The various principles of bioanalytical techniques used in biomedical sciences, environmental studies, life sciences, pharmaceutical analysis, molecular biology, and biotechnological research are comprehensively discussed in this book. Analytical instrumentation is also explained in as concise a manner as possible. Microscopy, centrifugation, chromatography, electrophoresis, spectroscopy, and radioisotope and immunodiagnostic techniques are the main topics focussed in this book. Techniques in molecular biology and recombinant DNA technology have also been described in detail.

Bioanalytical Chemistry

Author : Susan R. Mikkelsen
Publisher : John Wiley & Sons
ISBN 13 : 1118302540
Total Pages : 488 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Bioanalytical Chemistry by : Susan R. Mikkelsen

Download or read book Bioanalytical Chemistry written by Susan R. Mikkelsen and published by John Wiley & Sons. This book was released on 2016-03-07 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely, accessible survey of the multidisciplinary field of bioanalytical chemistry Provides an all in one approach for both beginners and experts, from a broad range of backgrounds, covering introductions, theory, advanced concepts and diverse applications for each method Each chapter progresses from basic concepts to applications involving real samples Includes three new chapters on Biomimetic Materials, Lab-on-Chip, and Analytical Methods Contains end-of-chapter problems and an appendix with selected answers

Nanobioanalytical Approaches to Medical Diagnostics

Author : Pawan Kumar Maurya
Publisher : Woodhead Publishing
ISBN 13 : 0323851657
Total Pages : 432 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Nanobioanalytical Approaches to Medical Diagnostics by : Pawan Kumar Maurya

Download or read book Nanobioanalytical Approaches to Medical Diagnostics written by Pawan Kumar Maurya and published by Woodhead Publishing. This book was released on 2022-06-21 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanobioanalytical Approaches to Medical Diagnostics reviews a range of nanobiomaterials and bioanalytical nano-devices for medical diagnostics. Nanobiomaterials and nano-devices are used in various bioanalytical and biochemical systems to provide real-time, point-of-care diagnostics. The specialized properties of nanoparticles allow them to be engineered and adapted to produce the required effect within a bioanalytical or biochemical system – offering targeted and detailed diagnostic results in a range of biomedical applications. This book covers both traditional biochemical and modern, combined nano-approaches to medical diagnostics. Chapters detail a range of in vitro, in vivo and ex vivo models for nanobioanalytics, including DNA and peptide-based, erythrocyte, microfluidic and more. In addition, sections also look at various different medical diagnostic applications, such as in cancer detection, infectious disease diagnosis and blood glucose sensing. Covers core principles and nano-approaches in bioanalytics for medical diagnostics Details a range of in vitro, in vivo and ex vivo models for nanobioanalytics, including spectroscopic analysis, erythrocyte models, microfluidics, and more Appeals to an interdisciplinary readership, spanning the fields of materials science, biomedical engineering and biochemical engineering

Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics

Author : Lisa Plitnick
Publisher : Academic Press
ISBN 13 : 0123948231
Total Pages : 432 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics by : Lisa Plitnick

Download or read book Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics written by Lisa Plitnick and published by Academic Press. This book was released on 2013-06-27 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics is a complete reference devoted to the nonclinical safety assessment of novel biopharmaceuticals, biosimilars, vaccines, cell and gene therapies and blood products. This book compares and contrasts these types of biologics with one another and with small molecule drugs, while incorporating the most current and essential international regulatory documents. Each section discusses a different type of biologic, as well as early characterization strategies, principles of study design, preclinical pharmacokinetics and pharmacodynamics and preclinical assays. An edited book that is authored by leading experts in the field, this comprehensive reference provides critical insights to all researchers involved in early through late stage biologics. Provides in-depth coverage of the process of nonclinical safety assessment and comprehensive reviews of each type of biopharmaceutical Contains the most pertinent international regulatory guidance documents for nonclinical evaluation Covers early de-risking strategies and designs of safety assessment programs for novel biopharmaceuticals and vaccines, as well as follow-on biologics or "biosimilars" A multi-authored book with chapters written by qualified experts in their respective fields

Bioanalytical Chemistry (Second Edition)

Author : Andreas Manz
Publisher : World Scientific Publishing Company
ISBN 13 : 1783266740
Total Pages : 257 pages
Book Rating : 4.7/5 (832 download)

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Book Synopsis Bioanalytical Chemistry (Second Edition) by : Andreas Manz

Download or read book Bioanalytical Chemistry (Second Edition) written by Andreas Manz and published by World Scientific Publishing Company. This book was released on 2015-06-04 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interdisciplinary knowledge is becoming increasingly important to the modern scientist. This invaluable textbook covers bioanalytical chemistry (mainly the analysis of proteins and DNA) and explains everything for the non-biologist. Electrophoresis, mass spectrometry, biosensors, bioassays, DNA and protein sequencing are not necessarily all included in conventional analytical chemistry textbooks. The book describes the basic principles and the applications of instrumental and molecular methods. It is particularly useful to chemistry and engineering students who already have some basic knowledge about analytical chemistry. This revised second edition contains a new chapter on optical spectroscopy, and updated methods and new references throughout.Andreas Manz received the 2015 Inventor Award for 'Lifetime Achievement' from the European Patent Office.Petra S Dittrich was presented with the Heinrich-Emanuel-Merck Award 2015 at EuroAnalysis2015 Conference.

Analytical Electrogenerated Chemiluminescence

Author : Neso Sojic
Publisher : Royal Society of Chemistry
ISBN 13 : 1788014146
Total Pages : 516 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Analytical Electrogenerated Chemiluminescence by : Neso Sojic

Download or read book Analytical Electrogenerated Chemiluminescence written by Neso Sojic and published by Royal Society of Chemistry. This book was released on 2019-11-19 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrogenerated chemiluminescence (ECL) is a powerful and versatile analytical technique, which is widely applied for biosensing and successfully commercialized in the healthcare diagnostic market. After introducing the fundamental concepts, this book will highlight the recent analytical applications with a special focus on immunoassays, genotoxicity, imaging, DNA and enzymatic assays. The topic is clearly at the frontier between several scientific domains involving analytical chemistry, electrochemistry, photochemistry, materials science, nanoscience and biology. This book is ideal for graduate students, academics and researchers in industry looking for a comprehensive guide to the different aspects of electrogenerated chemiluminescence.

Nanobiotechnology

Author : Christof M. Niemeyer
Publisher : John Wiley & Sons
ISBN 13 : 3527605916
Total Pages : 491 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Nanobiotechnology by : Christof M. Niemeyer

Download or read book Nanobiotechnology written by Christof M. Niemeyer and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is the key technology of the 21st century. The possibility to exploit the structures and processes of biomolecules for novel functional materials, biosensors, bioelectronics and medical applications has created the rapidly growing field of nanobiotechnology. Designed as a broad survey of the field, this book combines contributions from bioorganic and bioinorganic chemistry, molecular biology, materials science and bioanalytics to fathom the full scope of current and future developments. It is divided into four main sections: * Interphase Systems * Protein-based Nanostructures * DNA-based Nanostructures * Nanoanalytics Each chapter describes in detail currently available methods and contains numerous references to the primary literature, making this the perfect "field guide" for chemists, biologists and materials scientists who want to explore the fascinating world of nanobiotechnology.

Validation of Bioanalytical Methods

Author : Patric U. B. Vogel
Publisher : Springer Nature
ISBN 13 : 3658389133
Total Pages : 54 pages
Book Rating : 4.6/5 (583 download)

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Book Synopsis Validation of Bioanalytical Methods by : Patric U. B. Vogel

Download or read book Validation of Bioanalytical Methods written by Patric U. B. Vogel and published by Springer Nature. This book was released on 2023-02-25 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: this book, the validation of bioanalytical methods is described. In the quality control of biological medicinal products, bioanalytical methods are frequently used to check important properties such as the content or possible impurities. The methods used must provide trustworthy results so that no false conclusions are drawn when evaluating the results. The trustworthiness is ensured by validation. The validation of bioanalytical methods is illustrated by means of some examples.

Bioanalytical Aspects in Biological Therapeutics

Author : Xiaohui (Sophia) Xu
Publisher : John Wiley & Sons
ISBN 13 : 1119523214
Total Pages : 404 pages
Book Rating : 4.1/5 (195 download)

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Book Synopsis Bioanalytical Aspects in Biological Therapeutics by : Xiaohui (Sophia) Xu

Download or read book Bioanalytical Aspects in Biological Therapeutics written by Xiaohui (Sophia) Xu and published by John Wiley & Sons. This book was released on 2022-08-23 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioanalytical Aspects in Biological Therapeutics Deepen your understanding of how critical data are generated from bioanalysis In Bioanalytical Aspects in Biological Therapeutics, a team of renowned chemists, immunologists, and biologists delivers a timely and practical exploration of the diverse scientific and technical literature on the bioanalytical investigation of current biotherapeutics under development. The book discusses the challenges and considerations for bioanalytical support, covering a wide range of central topics in the field, including overview and basic immunology for testing of biological therapeutics, pharmacokinetic aspects, clinical immunogenicity prediction and testing, biomarker testing, biotransformation assessment for biologics, statistical aspects of bioanalytical testing, regulatory expectations, and more. Drug development and analysis professionals will learn how critical data are generated from bioanalysis and how proven tools and methods are applied to the development of biologics. Alongside coverage of topics like PK, immunogenicity, neutralizing antibody assays, and the importance of quality control for reagents, readers will benefit from: A thorough overview of the development of biotherapeutics and the role played by bioanalytical tests, as well as basic immunology for bioanalytical testing of biological therapeutics Comprehensive explorations of platform and instrument considerations in bioanalytical testing, pharmacokinetics assays, and biomarker analysis using LC-MS, LBA, and other technologies Practical discussions of immunogenicity prediction, preclinical and clinical anti-drug antibody assays, and bioanalytical schemes for anti-drug neutralizing antibody assays In-depth examinations of critical reagents in bioanalysis Regulatory expectations for bioanalytical method development, validation, and sample testing Perfect for pharmaceutical scientists in industry, Bioanalytical Aspects in Biological Therapeutics will also earn a place in the libraries of pharmaceutical regulators and other professionals working in pharmaceutical companies, as well as graduate students studying bioanalytical assays for biological therapeutics.