Pharmacology of Potassium Channels

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Author :
Publisher : Springer Nature
ISBN 13 : 3030840522
Total Pages : 546 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Pharmacology of Potassium Channels by : Nikita Gamper

Download or read book Pharmacology of Potassium Channels written by Nikita Gamper and published by Springer Nature. This book was released on 2021-09-27 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology.

Pharmacology of Potassium Channels

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Author :
Publisher : Springer
ISBN 13 : 9783030840549
Total Pages : 0 pages
Book Rating : 4.8/5 (45 download)

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Book Synopsis Pharmacology of Potassium Channels by : Nikita Gamper

Download or read book Pharmacology of Potassium Channels written by Nikita Gamper and published by Springer. This book was released on 2022-09-29 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology.

Frontiers in Pharmacology of Neurotransmitters

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Author :
Publisher : Springer Nature
ISBN 13 : 9811535566
Total Pages : 729 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Frontiers in Pharmacology of Neurotransmitters by : Puneet Kumar

Download or read book Frontiers in Pharmacology of Neurotransmitters written by Puneet Kumar and published by Springer Nature. This book was released on 2020-10-29 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous phenomenal advances have been made towards understanding the role of neurotransmitters in the pathophysiology of neurological disorders, and these have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of such disorders. This book provides a comprehensive and detailed explanation of brain neurotransmitters and their receptors and associated channels. It includes a basic introduction, and also discusses the functions and recent advances and their pharmacology, highlighting the role of various computer aided drug design (CADD) strategies for the development of therapeutic ligands to modulate these receptors/ion channels. Written in an easy-to-read style, it is intended for neuroscience and pharmaceutical students and researchers working in the area of brain neurotransmitters.

Potassium Channels And Their Modulators

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Author :
Publisher : CRC Press
ISBN 13 : 0203304411
Total Pages : 521 pages
Book Rating : 4.2/5 (33 download)

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Book Synopsis Potassium Channels And Their Modulators by : John M Evans

Download or read book Potassium Channels And Their Modulators written by John M Evans and published by CRC Press. This book was released on 2003-09-02 with total page 521 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potassium ions K+ ions are vital in physiological processes, particularly with regard to the cardiovascular system. Modulators influence the channels through which these ions flow and the research into modulator drugs of these channels is the subject of rapidly-advancing research. This work is intended to be of use as a tool for those working in the pharmaceutical industry. Early chapters concentrate on the synthesis and structure-activity relationships of potassium channel modulators. These are followed by discussion on the application of these drugs to different target organs, such as the cardiovascular system and the airways. The book concludes with a broad overview of clinical experience and future prospects.; The authors show how potassium channel activators and potassium channel blockers each have a role to play as therapeutic agents for many disorders, including asthma and respiratory tract disorders, diseases of the central nervous system such as epilepsy, and vascular diseases such as angina, peripheral vascular disease and high blood pressure. This book should therefore also be of interest to those researching into this wide range of diseases.

Voltage-Gated Ion Channels as Drug Targets

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 3527607749
Total Pages : 492 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Voltage-Gated Ion Channels as Drug Targets by : David J. Triggle

Download or read book Voltage-Gated Ion Channels as Drug Targets written by David J. Triggle and published by John Wiley & Sons. This book was released on 2006-08-21 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology. After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development. For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.

Ion Channel Pharmacology

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Author :
Publisher :
ISBN 13 :
Total Pages : 498 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Ion Channel Pharmacology by : Bernat Soria

Download or read book Ion Channel Pharmacology written by Bernat Soria and published by . This book was released on 1998 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: The improved understanding of ion channel structure, achieved through the use of molecular biology techniques, has opened the way for the development of new drugs targeted at specific types of ion channels. This book provides a comprehensive, single-volume overview of the effects of different drugs and toxins on ionic channels. The first part of the book deals with the development of ion channels, while subsequent chapters detail the electrophysiological properties and pharmacology of eight different types of ion channels, including intracellular, cyclic nucleotide-gated, and receptor operated channels. Drug effects in various cell types, along with the potential use of channels in therapeutics, are discussed for each channel type. Comprehensive and up-to-date, Ion Channel Pharmacology is an essential reference for every investigator in this fast-growing area of research.

Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9401139903
Total Pages : 586 pages
Book Rating : 4.4/5 (11 download)

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Book Synopsis Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters by : M. Morad

Download or read book Molecular Physiology and Pharmacology of Cardiac Ion Channels and Transporters written by M. Morad and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of cardiac ion channels and transporters has advanced remarkably in the last two decades with the development of patch-clamp and molecular biological techniques. This textbook offers a comprehensive overview of structures and functions of ion channels and transporters in the heart. Readers are first introduced to the molecular biology and electrophysiology of all the important ion channels. After discussing their developmental changes, the pharmacology and pathophysiology of clinically-relevant ion channels are reviewed. Molecular aspects of the cardiac excitation-contraction coupling and intracellular Ca2+ regulation by ion transporters are also described. The book will be useful to electrophysiologists, cardiac physiologists and pharmacologists, and molecular biologists interested in ion channels at all levels. For research specialists, the book will provide a perspective of the field. The book can be used as a reference source for working scientists in the fields of ion channels, biophysics, cardiac electrophysiology, and pharmacology. It is aimed at graduate and medical students, designed for use as a textbook for graduate and medical courses.

Potassium Channels

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Author :
Publisher : Humana Press
ISBN 13 : 9781603279833
Total Pages : 302 pages
Book Rating : 4.2/5 (798 download)

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Book Synopsis Potassium Channels by : Jonathan D. Lippiat

Download or read book Potassium Channels written by Jonathan D. Lippiat and published by Humana Press. This book was released on 2008-11-01 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the importance of potassium channels in cellular function, researchers have been challenged to develop tools and experimental procedures to probe the function and identify chemicals that modulate the behaviour of this super-family of ion channels. In Potassium Channels: Methods and Protocols, experts in the field present a range of experimental approaches that have been developed to investigate potassium channel structure, function, pharmacology, cell biology, gene expression, and their role in disease. Many of these techniques study potassium channels as cellular proteins as well as the resultant membrane biophysics. Written in the highly successful Methods in Molecular BiologyTM series format, the chapters contain brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section, which highlights tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Potassium Channels: Methods and Protocols provides a wide range of approaches in order to aid current research projects and inspire new investigations.

Potassium Channels: Advances in Research and Application: 2011 Edition

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Author :
Publisher : ScholarlyEditions
ISBN 13 : 1464942080
Total Pages : 61 pages
Book Rating : 4.4/5 (649 download)

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Book Synopsis Potassium Channels: Advances in Research and Application: 2011 Edition by :

Download or read book Potassium Channels: Advances in Research and Application: 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 61 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potassium Channels: Advances in Research and Application: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Potassium Channels in a concise format. The editors have built Potassium Channels: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Potassium Channels in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Potassium Channels: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Jasper's Basic Mechanisms of the Epilepsies

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Author :
Publisher : OUP USA
ISBN 13 : 0199746540
Total Pages : 1258 pages
Book Rating : 4.1/5 (997 download)

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Book Synopsis Jasper's Basic Mechanisms of the Epilepsies by : Jeffrey Noebels

Download or read book Jasper's Basic Mechanisms of the Epilepsies written by Jeffrey Noebels and published by OUP USA. This book was released on 2012-06-29 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.

Potassium Channels in Normal and Pathological Conditions

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Author :
Publisher : Leuven University Press
ISBN 13 : 9789061867012
Total Pages : 470 pages
Book Rating : 4.8/5 (67 download)

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Book Synopsis Potassium Channels in Normal and Pathological Conditions by : J. Vereecke

Download or read book Potassium Channels in Normal and Pathological Conditions written by J. Vereecke and published by Leuven University Press. This book was released on 1995 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Potassium Channel Modulators

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Author :
Publisher : Wiley-Blackwell
ISBN 13 : 9780632030446
Total Pages : 528 pages
Book Rating : 4.0/5 (34 download)

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Book Synopsis Potassium Channel Modulators by : AH Weston

Download or read book Potassium Channel Modulators written by AH Weston and published by Wiley-Blackwell. This book was released on 1993-01-18 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modulation of potassium channels plays a very important part in nerve cell function in the autonomic nervous system. Compounds are now in development which can open or close potassium channels and will have numerous therapeutic applications. The major areas of clinical relevance will be hypertension, asthma and irritable bladder syndrome. The book describes the pharmacology of the channels and strategies for the design of drugs which exploit them. It consists of 17 chapters by international experts in the field which are written at a high level and will be of interest to pharmacologists and those in related clinical research disciplines

Potassium Channels

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Author :
Publisher : Ellis Horwood
ISBN 13 :
Total Pages : 424 pages
Book Rating : 4.:/5 (44 download)

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Book Synopsis Potassium Channels by : Nigel S. Cook

Download or read book Potassium Channels written by Nigel S. Cook and published by Ellis Horwood. This book was released on 1990 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Potassium Channels as a Target for Clinical Therapeutics

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 1608052354
Total Pages : 104 pages
Book Rating : 4.6/5 (8 download)

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Book Synopsis Potassium Channels as a Target for Clinical Therapeutics by : Ivan Kocić

Download or read book Potassium Channels as a Target for Clinical Therapeutics written by Ivan Kocić and published by Bentham Science Publishers. This book was released on 2012-04-12 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This e-book presents an overview of the different substances capable of modulating potassium channels in relation to various clinical indications in cardiology, pulmonology, endocrinology and neurology. The possible benefits and side effects of potassium "

Handbook of Ion Channels

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Author :
Publisher : CRC Press
ISBN 13 : 1466551429
Total Pages : 682 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Handbook of Ion Channels by : Jie Zheng

Download or read book Handbook of Ion Channels written by Jie Zheng and published by CRC Press. This book was released on 2015-02-25 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: The New Benchmark for Understanding the Latest Developments of Ion ChannelsIon channels control the electrical properties of neurons and cardiac cells, mediate the detection and response to sensory stimuli, and regulate the response to physical stimuli. They can often interact with the cellular environment due to their location at the surface of ce

Voltage-gated Potassium Channels

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Author :
Publisher :
ISBN 13 :
Total Pages : 332 pages
Book Rating : 4.:/5 (323 download)

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Book Synopsis Voltage-gated Potassium Channels by : Sunny Sen Po

Download or read book Voltage-gated Potassium Channels written by Sunny Sen Po and published by . This book was released on 1994 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Potassium Channels in Cardiovascular Biology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461513030
Total Pages : 962 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Potassium Channels in Cardiovascular Biology by : Stephen L. Archer

Download or read book Potassium Channels in Cardiovascular Biology written by Stephen L. Archer and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potassium channels (K+) are membrane-spanning proteins which serve many important functions and are becoming a hot topic in physiology. K+ channels determine or modulate many functions of vascular smooth muscle, endothelial and inflammatory cells, and thus are central to regulation of arterial tone and control of cell proliferation. They are also promising targets for antihypertensive treatments with drugs which open and close specific types of K+ channels, making for an active field of research. With their ability to control vascular tone, voltage-gated K+ channels play a significant role in both pulmonary and systemic hypertension as well as in cardiac arrhythmias. This book will highlight the latest discoveries by leading researchers pertaining to the role of K+ channels in the heart and blood vessels in normal physiology and a variety of disease states.