Pharmacogenomics Of Alcohol And Drugs Of Abuse

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Pharmacogenomics of Alcohol and Drugs of Abuse

Author : Amitava Dasgupta
Publisher : CRC Press
ISBN 13 : 1439856117
Total Pages : 255 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Pharmacogenomics of Alcohol and Drugs of Abuse by : Amitava Dasgupta

Download or read book Pharmacogenomics of Alcohol and Drugs of Abuse written by Amitava Dasgupta and published by CRC Press. This book was released on 2012-04-23 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics is the basis of personalized medicine, which is said to be the medicine of the future. Understanding genetic variation in drug and alcohol response is vital for professionals working in rehabilitation programs. The same principles that are applicable for therapeutic drugs are also applicable for drugs of abuse. Pharmacogenomics can supplement traditional therapeutic drug monitoring, potentially predicting correct dosage before initiation of the drug therapy. Applying these principles to testing and treatment, Pharmacogenomics of Alcohol and Drugs of Abuse discusses the role of the clinical laboratory in the practice of personalized medicine. With contributions from a range of experts, the book presents the genetic aspects of alcohol metabolism and other drugs including marijuana, cocaine, and amphetamines. In addition to basic pharmacogenomic aspects, the book addresses slate and trait markers of drugs of abuse so readers can consider setting appropriate biomarker tests in their clinical laboratory.

Biological Vulnerability to Drug Abuse

Author :
Publisher :
ISBN 13 :
Total Pages : 200 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis Biological Vulnerability to Drug Abuse by :

Download or read book Biological Vulnerability to Drug Abuse written by and published by . This book was released on 1988 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph is based on papers and discussions from a technical review on biological vulnerability to drug abuse held on June 2 and 3, 1986, at Rockville, Maryland. The review meeting was sponsored by the Office of Science and the Division of Clinical Research, National Institute on Drug Abuse.

Critical Issues in Alcohol and Drugs of Abuse Testing

Author : Amitava Dasgupta
Publisher : Academic Press
ISBN 13 : 0128156082
Total Pages : 560 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Critical Issues in Alcohol and Drugs of Abuse Testing by : Amitava Dasgupta

Download or read book Critical Issues in Alcohol and Drugs of Abuse Testing written by Amitava Dasgupta and published by Academic Press. This book was released on 2019-01-10 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

The Genetic Basis of Alcohol and Drug Actions

Author : J.C. Crabbe Jr.
Publisher : Springer Science & Business Media
ISBN 13 : 1489920676
Total Pages : 393 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis The Genetic Basis of Alcohol and Drug Actions by : J.C. Crabbe Jr.

Download or read book The Genetic Basis of Alcohol and Drug Actions written by J.C. Crabbe Jr. and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: HISTORICAL BACKGROUND The use of genetic animal models in neuroscience and biomedical research is showing dramatic growth. The earliest application of these models to research on drug mechanisms was in the area of alcohol research. Mardones (1951) reported successful selective breeding of rats preferring and not preferring to drink alcohol under various conditions of dietary deficiency, suggesting genetic control of alcohol drinking. McClearn and Rodgers (1959, 1961) described differences among inbred mouse strains in preference for 10Ofo ethanol solutions versus tap water. Active exploration of this phenomenon continued until the early 1970s, eventually spawning the entire range of alcohol genetic research reviewed in Chapters 2 and 3 of this volume. Notably, oral alcohol self-administration has served as the basis for the development of several rat lines bred for preference or aversion, and these lines are very actively being investigated. The pioneering research of Dr. McClearn and others was very wide ranging in its conceptual scope and at least touched on all issues currently under intense investigation. The basic approach was to identify high and low preferrers among inbred strains of mice and to search for preference correlates in other traits. One major thrust of early research was to attempt to explain strain differences in preference as a function of underlying differences in patterns of caloric utilization. Reviews of these studies concluded that nutritional factors could not completely explain preference differences (Rod gers, 1966; McClearn, 1968).

Alcohol, Drugs, Genes and the Clinical Laboratory

Author : Amitava Dasgupta
Publisher : Academic Press
ISBN 13 : 012809334X
Total Pages : 238 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Alcohol, Drugs, Genes and the Clinical Laboratory by : Amitava Dasgupta

Download or read book Alcohol, Drugs, Genes and the Clinical Laboratory written by Amitava Dasgupta and published by Academic Press. This book was released on 2016-10-17 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials. Features accessible language for healthcare and safety professionals who are not experts in laboratory procedures Provides examples from clinical and everyday situations Explains how to interpret laboratory results and the latest genetic factors regarding drug and alcohol abuse

The Pharmacology of Alcohol and Drugs of Abuse and Addiction

Author : Norman S. Miller
Publisher :
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Pharmacology of Alcohol and Drugs of Abuse and Addiction by : Norman S. Miller

Download or read book The Pharmacology of Alcohol and Drugs of Abuse and Addiction written by Norman S. Miller and published by . This book was released on 1991 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: This book is intended for use by clinicians, researchers, residents, and students. The text includes sections on the pharmacology of abuse and addiction (neurochemistry, behavioral aspects, genetics, medical and psychiatric consequences, etc.), drug-drug interactions, abstinence and prevention.

Pharmacogenomics of Alcohol and Drugs of Abuse

Author : Amitava Dasgupta
Publisher : CRC Press
ISBN 13 : 1439856125
Total Pages : 243 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Pharmacogenomics of Alcohol and Drugs of Abuse by : Amitava Dasgupta

Biological Vulnerability to Drug Abuse

Author : Roy W. Pickens
Publisher :
ISBN 13 :
Total Pages : 185 pages
Book Rating : 4.:/5 (19 download)

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Book Synopsis Biological Vulnerability to Drug Abuse by : Roy W. Pickens

Download or read book Biological Vulnerability to Drug Abuse written by Roy W. Pickens and published by . This book was released on 1988 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Addictive Substances and Neurological Disease

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0128092963
Total Pages : 416 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Addictive Substances and Neurological Disease by : Ronald Ross Watson

Download or read book Addictive Substances and Neurological Disease written by Ronald Ross Watson and published by Academic Press. This book was released on 2017-02-18 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual’s lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances. Integrates current research on the actions of addictive substances in neurological disease Includes functional foods, such as caffeine beverages, that have habituating effects on the brain Provides a synopsis of key ideas associated with the consequences of addictive and habituating lifestyle substances

Integrating Psychological and Pharmacological Treatments for Addictive Disorders

Author : James MacKillop
Publisher : Routledge
ISBN 13 : 1317405854
Total Pages : 256 pages
Book Rating : 4.3/5 (174 download)

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Book Synopsis Integrating Psychological and Pharmacological Treatments for Addictive Disorders by : James MacKillop

Download or read book Integrating Psychological and Pharmacological Treatments for Addictive Disorders written by James MacKillop and published by Routledge. This book was released on 2017-07-06 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Integrating Psychological and Pharmacological Treatments for Addictive Disorders distills the complex literature on addiction, offering a curated toolbox of integrated pharmacological and psychotherapeutic treatments in chapters authored by leading experts. Introductory chapters on the epidemiology, etiology, and fundamentals of addiction treatment provide a concise overview of the state of the field. Subsequent chapters then focus on the treatment of specific substance use disorders and on gambling disorder. Finally, a chapter on the treatment of addiction in primary care addresses the opportunities for clinical care in non-specialist outpatient settings. Physicians, psychologists, social workers, and other mental health professionals will come away from the book with an essential understanding of evidence-based practice in treating addiction and the scientific foundations of those approaches. .

The SAGE Handbook of Drug & Alcohol Studies

Author : Kim Wolff
Publisher : SAGE
ISBN 13 : 1473944201
Total Pages : 840 pages
Book Rating : 4.4/5 (739 download)

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Book Synopsis The SAGE Handbook of Drug & Alcohol Studies by : Kim Wolff

Download or read book The SAGE Handbook of Drug & Alcohol Studies written by Kim Wolff and published by SAGE. This book was released on 2016-10-18 with total page 840 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions from leading international academics across the biological sciences, this handbook takes a critical look at the key contemporary issues and debates in the field. The 31 chapters are divided into four parts: Part I Determination of Substance Misuse Part II PK and PD in Relation to Patterns of Use Part III Detection and Treatment of Drug and Alcohol Use Part IV Controversies and New Approaches This Handbook is an excellent reference text for the growing number of academics, students, scientists and practitioners in the drug and alcohol studies community, and will be a vital resource to the allied professions involved in work-place drug testing, clinical toxicology, and forensic science.

Principles of Psychiatric Genetics

Author : John I. Nurnberger
Publisher : Cambridge University Press
ISBN 13 : 0521896495
Total Pages : 415 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Principles of Psychiatric Genetics by : John I. Nurnberger

Download or read book Principles of Psychiatric Genetics written by John I. Nurnberger and published by Cambridge University Press. This book was released on 2012-09-13 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.

Absolute Addiction Psychiatry Review

Author : Carla Marienfeld
Publisher : Springer Nature
ISBN 13 : 303033404X
Total Pages : 376 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Absolute Addiction Psychiatry Review by : Carla Marienfeld

Download or read book Absolute Addiction Psychiatry Review written by Carla Marienfeld and published by Springer Nature. This book was released on 2020-03-06 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a tool for general psychiatrists, medical students, residents, and fellows looking for a clinically relevant and high-yield overview of addiction psychiatry in preparation for their board exams – or for everyday clinical practice. Written by expert educators in addiction psychiatry, the text is organized by substances misused and populations affected. This book serves as both a primary learning tool for those new to the field, as well as a reference for those working in addiction treatment. Each chapter begins with summaries of high yield clinical pearls, followed by general information including treatment, and then ends with accompanying board-style review questions. The scope includes understanding substances of misuse and substance use disorders (SUDs), how to evaluate, diagnose, and monitor SUDs, how to treat SUDs both pharmacologically and behaviorally, and critical information for specific populations of patients. Absolute Addiction Psychiatry for Clinical Practice and Review is an excellent resource for all medical students, residents, fellows, and professionals taking certification exams in addiction, including those in psychiatry, addiction medicine, emergency medicine, internal medicine, pain medicine, and others. The chapter "Laboratory Testing for Substance Use Disorders" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Handbook of Drug Interactions

Author : Ashraf Mozayani
Publisher : Springer Science & Business Media
ISBN 13 : 1592596541
Total Pages : 662 pages
Book Rating : 4.5/5 (925 download)

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Book Synopsis Handbook of Drug Interactions by : Ashraf Mozayani

Download or read book Handbook of Drug Interactions written by Ashraf Mozayani and published by Springer Science & Business Media. This book was released on 2003-10-15 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise compilation of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. For each class of drugs the authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Comprehensive and easy-to-use, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and toxicologists with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.

Handbook of Drug Monitoring Methods

Author : Amitava Dasgupta
Publisher : Springer Science & Business Media
ISBN 13 : 1588297802
Total Pages : 441 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis Handbook of Drug Monitoring Methods by : Amitava Dasgupta

Download or read book Handbook of Drug Monitoring Methods written by Amitava Dasgupta and published by Springer Science & Business Media. This book was released on 2007-10-23 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written in a handbook style with specific methods and tips on eliminating false positive and false negative results, this book is a practical guide to the detailed mechanisms of such occurrences.

Pharmacogenomics in Clinical Therapeutics

Author : Loralie J. Langman
Publisher : John Wiley & Sons
ISBN 13 : 1119959586
Total Pages : 400 pages
Book Rating : 4.1/5 (199 download)

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Book Synopsis Pharmacogenomics in Clinical Therapeutics by : Loralie J. Langman

Download or read book Pharmacogenomics in Clinical Therapeutics written by Loralie J. Langman and published by John Wiley & Sons. This book was released on 2012-01-09 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics is the basis of personalized medicine which will be the medicine of the future. Through both reducing the numbers of adverse drug reactions and improving the use of existing drugs in targeted populations, pharmacogenomics represents a real advance on traditional therapeutic drug monitoring. Pharmacogenomics in Clinical Therapeutics provides an introduction to the principles of pharmacogenomics before addressing the pharmacogenomic aspects of key therapeutic areas such as warfarin therapy, cancer chemotherapy, therapy with immunosuppressants, antiretroviral therapy, and psychoactive drugs. It also includes methods of pharmacogenomic testing and the pharmacogenomic aspects of drug–drug interactions. From a team of expert contributors, Pharmacogenomics in Clinical Therapeutics is a comprehensive overview of the current state of pharmacogenomics in pharmacotherapy for all clinicians, pharmacologists and clinical laboratory professionals. It is also a guide for practicing clinicians and health care professionals to the basic principles of pharmacogenomics, laboratory tests currently available to aid clinicians, and the future promise of this developing field.

Textbook of Personalized Medicine

Author : Kewal K. Jain
Publisher : Humana Press
ISBN 13 : 1493925539
Total Pages : 762 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain

Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Humana Press. This book was released on 2015-03-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.