Pharmacogenetics: Making cancer treatment safer and more effective

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Publisher : Springer Science & Business Media
ISBN 13 : 9048186188
Total Pages : 190 pages
Book Rating : 4.0/5 (481 download)

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Book Synopsis Pharmacogenetics: Making cancer treatment safer and more effective by : William G. Newman

Download or read book Pharmacogenetics: Making cancer treatment safer and more effective written by William G. Newman and published by Springer Science & Business Media. This book was released on 2010-07-20 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemotherapy has made a dramatic difference to improved survival in patients with cancer. However, not all patients respond and some experience serious side effects. "Pharmacogenetics: Making cancer treatment safer and more effective" is an up to date summary of the exciting new field of how genetic testing can tailor more effective prescription in oncology. It is targeted at oncologists and professionals involved in the treatment of patients with cancer. It provides a core background in genetics and pharmacological principles before providing chapters from acknowledged experts in the field on genetic tests in specific cancer types, including breast, bowel and lung cancer. Clinical cases are used to illustrate the practical application of this knowledge. Chapters on ethics, health economics and the industry aspects of pharmacogenetics set out the challenges and opportunities afforded by this new science.

Pharmacogenetics and Pharmacogenomics of Colorectal Cancer: Moving Towards Personalized Medicine

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Publisher :
ISBN 13 : 9789535100287
Total Pages : pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis Pharmacogenetics and Pharmacogenomics of Colorectal Cancer: Moving Towards Personalized Medicine by : Joseph Ciccolini

Download or read book Pharmacogenetics and Pharmacogenomics of Colorectal Cancer: Moving Towards Personalized Medicine written by Joseph Ciccolini and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Recent Developments in Pharmacogenetics and Pharmacogenomics

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Publisher : Frontiers Media SA
ISBN 13 : 2889716481
Total Pages : 132 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Recent Developments in Pharmacogenetics and Pharmacogenomics by : Henk-Jan Guchelaar

Download or read book Recent Developments in Pharmacogenetics and Pharmacogenomics written by Henk-Jan Guchelaar and published by Frontiers Media SA. This book was released on 2021-11-16 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacogenetics and Pharmacogenomics of Colorectal Cancer

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Publisher :
ISBN 13 : 9789535100287
Total Pages : 1 pages
Book Rating : 4.1/5 (2 download)

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Book Synopsis Pharmacogenetics and Pharmacogenomics of Colorectal Cancer by : Joseph Ciccolini

Download or read book Pharmacogenetics and Pharmacogenomics of Colorectal Cancer written by Joseph Ciccolini and published by . This book was released on 2012 with total page 1 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenetics and Pharmacogenomics of Colorectal Cancer: Moving Towards Personalized Medicine.

Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response

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Publisher : Springer Science & Business Media
ISBN 13 : 1603270884
Total Pages : 379 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response by : Federico Innocenti

Download or read book Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response written by Federico Innocenti and published by Springer Science & Business Media. This book was released on 2008-10-30 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics and Pharmacogenomics in Anticancer Drug Development and Clinical Response provides the most comprehensive body of knowledge available on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients. As a consequence of the intrinsic chromosomal and genetic instability of the tumor genome, it is generally believed that tailoring of chemotherapy in cancer - tients might be achieved by molecular analysis of patient tumor DNA. In addition, to reduce the toxicity risk of patients, the tumor DNA information should be in- grated with the available data on polymorphic drug-metabolizing enzyme and tra- porter genes mediating the exposure of patients to active drugs and/or their active metabolites. The chapters of this book clearly show how DNA information from both the host (germline) and the tumor should be taken into account for rational selection of drug therapies in cancer patients, an aspect that received little attention, despite its importance. The availability of new molecular approaches to the selection of drug therapy is an emerging need, because the traditional approach based on the evaluation of patient and tumor characteristics is clearly far from optimal. Many treated patients do not experience signi?cant bene?ts from the treatment, while they often experience moderate to severe toxicities. In addition, the development and clinical use of novel molecularly targeted agents (alone or in combination with classical cytotoxic therapy) requires the und- standing of the molecular features of the tumors and the identi?cation of tumor markers of response.

Clinical Applications of Pharmacogenetics

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Publisher : BoD – Books on Demand
ISBN 13 : 953510389X
Total Pages : 308 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Clinical Applications of Pharmacogenetics by : Despina Sanoudou

Download or read book Clinical Applications of Pharmacogenetics written by Despina Sanoudou and published by BoD – Books on Demand. This book was released on 2012-03-21 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly evolving field of Pharmacogenetics aims at identifying the genetic factors implicated in the inter-individual variation of drug response. These factors could enable patient sub-classification based on their treatment needs thus expediting drug development and promoting personalized, safer and more effective treatments. This book presents Pharmacogenetic examples from a broad spectrum of different drugs, for different diseases, which are representative of different stages of evaluation or application. It has been designed so as to serve both the unfamiliar reader through explanations of basic Pharmacogenetic concepts, the clinician with presentation of the latest developments and international guidelines, and the research scientist with examples of Pharmacogenetic applications, discussions on the limitations and an outlook on the new scientific trends in this field.

The Future of 'pharmacogenome' and the Role of Genetic Counseling

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Publisher :
ISBN 13 :
Total Pages : 86 pages
Book Rating : 4.:/5 (865 download)

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Book Synopsis The Future of 'pharmacogenome' and the Role of Genetic Counseling by : Ahmen Nabiel Mohammed

Download or read book The Future of 'pharmacogenome' and the Role of Genetic Counseling written by Ahmen Nabiel Mohammed and published by . This book was released on 2013 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:

10 Years of Pharmacogenetics and Pharmacogenomics

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Publisher : Frontiers Media SA
ISBN 13 : 2889638286
Total Pages : 281 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis 10 Years of Pharmacogenetics and Pharmacogenomics by : Jose Agundez

Download or read book 10 Years of Pharmacogenetics and Pharmacogenomics written by Jose Agundez and published by Frontiers Media SA. This book was released on 2020-07-08 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Specialty Section “Pharmacogenetics and Pharmacogenomics” makes part of two different Journals: Frontiers in Pharmacology and Frontiers in Genetics. This Specialty Section focuses on the mechanisms by which genetic variations influence drug effects and adverse drug events, and cover basic research, clinical translation, applications in drug development and regulatory issues related to this field. Also, studies addressing the role of other factors such as epigenetics, phenotypic factors or drug-drug interactions on drug pharmacokinetics or pharmacodynamics are welcome. The editorial board is composed of 34 Associate Editors which, together with the Guest Associate Editors and the Reviewer Editors, constitute a team of nearly 340 leading experts in the field of Pharmacogenetics and Pharmacogenomics. This guarantees high quality in the reviewing process as well as short review times. A look back: 10 years of Frontiers in Pharmacogenetics & Pharmacogenomics (Continued in eBook)

The Genetics and Pharmacogenetics of Colorectal Cancer

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (896 download)

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Book Synopsis The Genetics and Pharmacogenetics of Colorectal Cancer by : Christopher G. Smith

Download or read book The Genetics and Pharmacogenetics of Colorectal Cancer written by Christopher G. Smith and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetics and Pharmacogenetics of Colorectal Cancer

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Publisher :
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.:/5 (87 download)

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Book Synopsis Genetics and Pharmacogenetics of Colorectal Cancer by : Christopher G. Smith

Download or read book Genetics and Pharmacogenetics of Colorectal Cancer written by Christopher G. Smith and published by . This book was released on 2011 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacogenomics in Admixed Populations

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Publisher : CRC Press
ISBN 13 : 1498713793
Total Pages : 222 pages
Book Rating : 4.4/5 (987 download)

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Book Synopsis Pharmacogenomics in Admixed Populations by : Dr. G. Suarez-Kurtz

Download or read book Pharmacogenomics in Admixed Populations written by Dr. G. Suarez-Kurtz and published by CRC Press. This book was released on 2007-08-03 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ethnic specificity has become an integral part of research in the overlapping sciences of pharmacogenetics and pharmacogenomics. Pharmacogenomics in Admixed Populations was conceived to compile pharmacogenetic/-genomic (PGx) data from peoples of four continents: Africa, America, Asia and Oceania, where admixture and population stratification occurs

Investigation of the Pharmacogenetics of Colorectal Cancer

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (16 download)

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Book Synopsis Investigation of the Pharmacogenetics of Colorectal Cancer by : Michelle Coffey

Download or read book Investigation of the Pharmacogenetics of Colorectal Cancer written by Michelle Coffey and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Preventive and Predictive Genetics: Towards Personalised Medicine

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Publisher : Springer
ISBN 13 : 3319153447
Total Pages : 388 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Preventive and Predictive Genetics: Towards Personalised Medicine by : Godfrey Grech

Download or read book Preventive and Predictive Genetics: Towards Personalised Medicine written by Godfrey Grech and published by Springer. This book was released on 2015-06-24 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.

Textbook of Personalized Medicine

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Publisher : Humana Press
ISBN 13 : 1493925539
Total Pages : 762 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Textbook of Personalized Medicine by : Kewal K. Jain

Download or read book Textbook of Personalized Medicine written by Kewal K. Jain and published by Humana Press. This book was released on 2015-03-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.

Molecular Medicine

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Publisher : BoD – Books on Demand
ISBN 13 : 183962759X
Total Pages : 168 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Molecular Medicine by : Sinem Nalbantoglu

Download or read book Molecular Medicine written by Sinem Nalbantoglu and published by BoD – Books on Demand. This book was released on 2019-11-06 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular medicine is an applied science focused on human genes/transcripts, proteins, metabolites, and metabolic networks that describes molecular and cellular processes of health and disease onset and progression. Molecular medicine-based integrative identification and characterization of biomarker targets and their clinical translations is essential to explain/decipher the mechanism(s) underlying physiological pathways and pathological conditions, and acquire cell-targeted early interventional and therapeutic strategies in the context of precision medicine and public health. Principally, Molecular Medicine provides an overview of the latest headlines/developments of systems and molecular medicine, highlighting the emerging high-throughput technologies, promising potential applications, and progress in biomedical research and development strategies.

Pharmacogenetics of Advanced Colorectal Cancer

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Publisher :
ISBN 13 :
Total Pages : 292 pages
Book Rating : 4.:/5 (896 download)

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Book Synopsis Pharmacogenetics of Advanced Colorectal Cancer by : Ayman Madi

Download or read book Pharmacogenetics of Advanced Colorectal Cancer written by Ayman Madi and published by . This book was released on 2011 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Pharmacogenetics of Advanced Colorectal Cancer Treatment

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Publisher :
ISBN 13 : 9789090261126
Total Pages : 183 pages
Book Rating : 4.2/5 (611 download)

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Book Synopsis Pharmacogenetics of Advanced Colorectal Cancer Treatment by : Jan Pander

Download or read book Pharmacogenetics of Advanced Colorectal Cancer Treatment written by Jan Pander and published by . This book was released on 2011 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: