Making Medicines Affordable

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Publisher : National Academies Press
ISBN 13 : 0309468086
Total Pages : 235 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Making Medicines Affordable by : National Academies of Sciences, Engineering, and Medicine

Download or read book Making Medicines Affordable written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-03-01 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thanks to remarkable advances in modern health care attributable to science, engineering, and medicine, it is now possible to cure or manage illnesses that were long deemed untreatable. At the same time, however, the United States is facing the vexing challenge of a seemingly uncontrolled rise in the cost of health care. Total medical expenditures are rapidly approaching 20 percent of the gross domestic product and are crowding out other priorities of national importance. The use of increasingly expensive prescription drugs is a significant part of this problem, making the cost of biopharmaceuticals a serious national concern with broad political implications. Especially with the highly visible and very large price increases for prescription drugs that have occurred in recent years, finding a way to make prescription medicinesâ€"and health care at largeâ€"more affordable for everyone has become a socioeconomic imperative. Affordability is a complex function of factors, including not just the prices of the drugs themselves, but also the details of an individual's insurance coverage and the number of medical conditions that an individual or family confronts. Therefore, any solution to the affordability issue will require considering all of these factors together. The current high and increasing costs of prescription drugsâ€"coupled with the broader trends in overall health care costsâ€"is unsustainable to society as a whole. Making Medicines Affordable examines patient access to affordable and effective therapies, with emphasis on drug pricing, inflation in the cost of drugs, and insurance design. This report explores structural and policy factors influencing drug pricing, drug access programs, the emerging role of comparative effectiveness assessments in payment policies, changing finances of medical practice with regard to drug costs and reimbursement, and measures to prevent drug shortages and foster continued innovation in drug development. It makes recommendations for policy actions that could address drug price trends, improve patient access to affordable and effective treatments, and encourage innovations that address significant needs in health care.

Perspectives on Pharmaceutical Pricing Practices

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Publisher :
ISBN 13 :
Total Pages : 74 pages
Book Rating : 4.3/5 (121 download)

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Book Synopsis Perspectives on Pharmaceutical Pricing Practices by : United States. Congress. House. Committee on Commerce. Subcommittee on Oversight and Investigations

Download or read book Perspectives on Pharmaceutical Pricing Practices written by United States. Congress. House. Committee on Commerce. Subcommittee on Oversight and Investigations and published by . This book was released on 1996 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Discovery

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Publisher : John Wiley & Sons
ISBN 13 : 111835446X
Total Pages : 572 pages
Book Rating : 4.1/5 (183 download)

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Book Synopsis Drug Discovery by : Jie Jack Li

Download or read book Drug Discovery written by Jie Jack Li and published by John Wiley & Sons. This book was released on 2013-04-03 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sets forth the history, state of the science, and future directions of drug discovery Edited by Jie Jack Li and Nobel laureate E. J. Corey, two leading pioneers in drug discovery and medicinal chemistry, this book synthesizes great moments in history, the current state of the science, and future directions of drug discovery into one expertly written and organized work. Exploring all major therapeutic areas, the book introduces readers to all facets and phases of drug discovery, including target selection, biological testing, drug metabolism, and computer-assisted drug design. Drug Discovery features chapters written by an international team of pharmaceutical and medicinal chemists. Contributions are based on a thorough review of the current literature as well as the authors' firsthand laboratory experience in drug discovery. The book begins with the history of drug discovery, describing groundbreaking moments in the field. Next, it covers such topics as: Target identification and validation Drug metabolism and pharmacokinetics Central nervous system drugs In vitro and in vivo assays Cardiovascular drugs Cancer drugs Each chapter features a case study, helping readers understand how science is put into practice throughout all phases of drug discovery. References at the end of each chapter serve as a gateway to groundbreaking original research studies and reviews in the field. Drug Discovery is ideal for newcomers to medicinal chemistry and drug discovery, providing a comprehensive overview of the field. Veterans in the field will also benefit from the perspectives of leading international experts in all aspects of drug discovery.

WHO Guideline on Country Pharmaceutical Pricing Policies

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)

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Book Synopsis WHO Guideline on Country Pharmaceutical Pricing Policies by : world health organization

Download or read book WHO Guideline on Country Pharmaceutical Pricing Policies written by world health organization and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

OECD Health Policy Studies Pharmaceutical Pricing Policies in a Global Market

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Publisher : OECD Publishing
ISBN 13 : 9264044159
Total Pages : 219 pages
Book Rating : 4.2/5 (64 download)

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Book Synopsis OECD Health Policy Studies Pharmaceutical Pricing Policies in a Global Market by : OECD

Download or read book OECD Health Policy Studies Pharmaceutical Pricing Policies in a Global Market written by OECD and published by OECD Publishing. This book was released on 2008-09-24 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report assesses how pharmaceutical pricing and reimbursement policies have contributed to the achievement of certain health policy objectives, and it examines the national and transnational effects of these policies.

U.S. Health in International Perspective

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Publisher : National Academies Press
ISBN 13 : 0309264146
Total Pages : 421 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis U.S. Health in International Perspective by : National Research Council

Download or read book U.S. Health in International Perspective written by National Research Council and published by National Academies Press. This book was released on 2013-04-12 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: The United States is among the wealthiest nations in the world, but it is far from the healthiest. Although life expectancy and survival rates in the United States have improved dramatically over the past century, Americans live shorter lives and experience more injuries and illnesses than people in other high-income countries. The U.S. health disadvantage cannot be attributed solely to the adverse health status of racial or ethnic minorities or poor people: even highly advantaged Americans are in worse health than their counterparts in other, "peer" countries. In light of the new and growing evidence about the U.S. health disadvantage, the National Institutes of Health asked the National Research Council (NRC) and the Institute of Medicine (IOM) to convene a panel of experts to study the issue. The Panel on Understanding Cross-National Health Differences Among High-Income Countries examined whether the U.S. health disadvantage exists across the life span, considered potential explanations, and assessed the larger implications of the findings. U.S. Health in International Perspective presents detailed evidence on the issue, explores the possible explanations for the shorter and less healthy lives of Americans than those of people in comparable countries, and recommends actions by both government and nongovernment agencies and organizations to address the U.S. health disadvantage.

Clinical Practice Guidelines We Can Trust

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Publisher : National Academies Press
ISBN 13 : 030921646X
Total Pages : 217 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Clinical Practice Guidelines We Can Trust by : Institute of Medicine

Download or read book Clinical Practice Guidelines We Can Trust written by Institute of Medicine and published by National Academies Press. This book was released on 2011-06-16 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in medical, biomedical and health services research have reduced the level of uncertainty in clinical practice. Clinical practice guidelines (CPGs) complement this progress by establishing standards of care backed by strong scientific evidence. CPGs are statements that include recommendations intended to optimize patient care. These statements are informed by a systematic review of evidence and an assessment of the benefits and costs of alternative care options. Clinical Practice Guidelines We Can Trust examines the current state of clinical practice guidelines and how they can be improved to enhance healthcare quality and patient outcomes. Clinical practice guidelines now are ubiquitous in our healthcare system. The Guidelines International Network (GIN) database currently lists more than 3,700 guidelines from 39 countries. Developing guidelines presents a number of challenges including lack of transparent methodological practices, difficulty reconciling conflicting guidelines, and conflicts of interest. Clinical Practice Guidelines We Can Trust explores questions surrounding the quality of CPG development processes and the establishment of standards. It proposes eight standards for developing trustworthy clinical practice guidelines emphasizing transparency; management of conflict of interest ; systematic review-guideline development intersection; establishing evidence foundations for and rating strength of guideline recommendations; articulation of recommendations; external review; and updating. Clinical Practice Guidelines We Can Trust shows how clinical practice guidelines can enhance clinician and patient decision-making by translating complex scientific research findings into recommendations for clinical practice that are relevant to the individual patient encounter, instead of implementing a one size fits all approach to patient care. This book contains information directly related to the work of the Agency for Healthcare Research and Quality (AHRQ), as well as various Congressional staff and policymakers. It is a vital resource for medical specialty societies, disease advocacy groups, health professionals, private and international organizations that develop or use clinical practice guidelines, consumers, clinicians, and payers.

Pharmaceutical Care Practice

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Author :
Publisher : McGraw-Hill Professional Publishing
ISBN 13 :
Total Pages : 392 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Pharmaceutical Care Practice by : Robert J. Cipolle

Download or read book Pharmaceutical Care Practice written by Robert J. Cipolle and published by McGraw-Hill Professional Publishing. This book was released on 1998 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advent of the new pharmaceutical practice paradigm, critical changes are occurring in pharmacy education and practice. Pharmaceutical Care Practice is authored by the key leaders in the development of this new practice model, which features an increased focus on patient-oriented care. This book explains these changes in comprehensive detail. This text provides all the implementation strategies in step-by-step detail to operate in this new environment. Its versatility and depth enable it to be used as a basis for improvements in the pharmacy curriculum and throughout clinical practice.

The Therapeutic Perspective

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Publisher : Princeton University Press
ISBN 13 : 1400864631
Total Pages : 385 pages
Book Rating : 4.4/5 (8 download)

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Book Synopsis The Therapeutic Perspective by : John Harley Warner

Download or read book The Therapeutic Perspective written by John Harley Warner and published by Princeton University Press. This book was released on 2014-07-14 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new paperback edition makes available John Harley Warner's highly influential, revisionary history of nineteenth-century American medicine. Deftly integrating social and intellectual perspectives, Warner explores a crucial shift in medical history, when physicians no longer took for granted such established therapies as bloodletting, alcohol, and opium and began to question the sources and character of their therapeutic knowledge. He examines what this transformation meant in terms of patient care and assesses the impact of clinical research, educational reform, unorthodox medical movements, newly imported European method, and the products of laboratory science on medical ideology and action. Originally published in 1997. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

The Soul of Medicine

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Publisher : JHU Press
ISBN 13 : 1421403951
Total Pages : 274 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis The Soul of Medicine by : John R. Peteet

Download or read book The Soul of Medicine written by John R. Peteet and published by JHU Press. This book was released on 2011-12-15 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: To what extent should spiritual information be part of a patient’s medical assessment? How should physicians respond when patients refuse life-saving care on religious grounds? Should doctors pray with their patients? Questions such as these raise deeper ones about the goals of medicine and the nature of healing. In a set of engaging and candid essays, The Soul of Medicine explores the role and influence of spirituality in clinical practice, professionalism, and medical education. The contributors to this volume approach this topic from their own spiritual perspectives—Jewish, Christian, Muslim, Buddhist, Hindu, New Age / Eclectic, secular, Jehovah’s Witnesses, and Christian Scientist. Their thought-provoking essays provide rich insights not only into the needs of patients with various world views but also into how spirituality influences the practice of medicine. When their own spiritual issues arise in medical practice, physicians rely on their professionalism, ethics, and education. To better understand how various world views are incorporated into clinical work, doctors must ask themselves—as these contributors have—a series of important questions: What insights about life and healing does your faith provide? How does your faith challenge or reinforce contemporary medicine? How do you assess and address spirituality in clinical practice? How do your own beliefs influence your interactions with patients? The Soul of Medicine encourages medical students and practitioners to recognize the spiritual dimensions of medicine, to consider how these dimensions inform their own education and practice, and to be compassionate about their patients’—and their own—religious beliefs.

Evidence-Based Medicine and the Changing Nature of Health Care

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Publisher : National Academies Press
ISBN 13 : 0309113695
Total Pages : 202 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Evidence-Based Medicine and the Changing Nature of Health Care by : Institute of Medicine

Download or read book Evidence-Based Medicine and the Changing Nature of Health Care written by Institute of Medicine and published by National Academies Press. This book was released on 2008-09-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on the work of the Roundtable on Evidence-Based Medicine, the 2007 IOM Annual Meeting assessed some of the rapidly occurring changes in health care related to new diagnostic and treatment tools, emerging genetic insights, the developments in information technology, and healthcare costs, and discussed the need for a stronger focus on evidence to ensure that the promise of scientific discovery and technological innovation is efficiently captured to provide the right care for the right patient at the right time. As new discoveries continue to expand the universe of medical interventions, treatments, and methods of care, the need for a more systematic approach to evidence development and application becomes increasingly critical. Without better information about the effectiveness of different treatment options, the resulting uncertainty can lead to the delivery of services that may be unnecessary, unproven, or even harmful. Improving the evidence-base for medicine holds great potential to increase the quality and efficiency of medical care. The Annual Meeting, held on October 8, 2007, brought together many of the nation's leading authorities on various aspects of the issues - both challenges and opportunities - to present their perspectives and engage in discussion with the IOM membership.

Cost Effectiveness in Health and Medicine

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Publisher : Oxford University Press
ISBN 13 : 0190492937
Total Pages : 537 pages
Book Rating : 4.1/5 (94 download)

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Book Synopsis Cost Effectiveness in Health and Medicine by : Peter J. Neumann

Download or read book Cost Effectiveness in Health and Medicine written by Peter J. Neumann and published by Oxford University Press. This book was released on 2017 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: CEAs (cost-effectiveness analyses) are used by decision makers in the health sector to make enlightened evaluations and this book provides an in depth look at how to evaluate the evaluator. The book is aimed specifically at Public health specialists.

Pain Management and the Opioid Epidemic

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Publisher : National Academies Press
ISBN 13 : 0309459575
Total Pages : 483 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Pain Management and the Opioid Epidemic by : National Academies of Sciences, Engineering, and Medicine

Download or read book Pain Management and the Opioid Epidemic written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-09-28 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Discursive Perspectives in Therapeutic Practice

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Publisher : OUP Oxford
ISBN 13 : 0191625744
Total Pages : 352 pages
Book Rating : 4.1/5 (916 download)

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Book Synopsis Discursive Perspectives in Therapeutic Practice by : Andy Lock

Download or read book Discursive Perspectives in Therapeutic Practice written by Andy Lock and published by OUP Oxford. This book was released on 2012-04-05 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: For an endeavour that is largely based on conversation it may seem obvious to suggest that psychotherapy is discursive. After all, therapists and clients primarily use talk, or forms of discourse, to accomplish therapeutic aims. However, talk or discourse has usually been seen as secondary to the actual business of therapy - a necessary conduit for exhanging information between therapist and client, but seldom more. Psychotherapy primarily developed by mapping particular experiential domains in ways responsive to human intervention. Only recently though has the role that discourse plays been recognized as a focus in itself for analysis and intervention. Discursive Perspectives in Therapeutic Practice presents an overview of discursive perspectives in therapy, along with an account of their conceptual underpinnings. The book starts by setting out the case for a discursive and relational approach to therapy by justaposing it to the tradition that that leads to the diagnostic approach of the DSM-V and medical psychiatry. It then presents a thorough review of a range of innovative discursive methods, each presented by an authority in their respective area. The book shows how discursive therapies can help people construct a better sense of their world, and move beyond the constraints caused by the cultural preconceptions, opinions, and values the client has about the world. The book makes a unique contribution to the philosophy and psychiatry literature in examining both the philosophical bases of discursive therapy, whilst also showing how discursive perspectives can be applied in real therapeutic situations. The book will be of great value and interest to psychotherapists and psychiatrists wishing to understand, explore, and apply these innovative techniques.

Handbook of Integrative Clinical Psychology, Psychiatry, and Behavioral Medicine

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Publisher : Springer Publishing Company
ISBN 13 : 0826110959
Total Pages : 910 pages
Book Rating : 4.8/5 (261 download)

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Book Synopsis Handbook of Integrative Clinical Psychology, Psychiatry, and Behavioral Medicine by : Roland A. Carlstedt, PhD

Download or read book Handbook of Integrative Clinical Psychology, Psychiatry, and Behavioral Medicine written by Roland A. Carlstedt, PhD and published by Springer Publishing Company. This book was released on 2009-12-14 with total page 910 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is the long-awaited text on interdisciplinary treatment and assessment of, among other clinical topics, brain-derived behavioral, cognitive, and neurological disorders...." --Niels Birbaumer, PhD University of T ̧bingen, Germany Member of the German Academy of Sciences, Leopoldina "Gone is the unidimensional approach of the expert summarizing a topic from a single vantage point. Instead, the content shifts laterally, embracing not only interdisciplinary expertise, but an integrative way of thinking that transcends each discipline....What makes the Handbook so refreshing is that this cross pollination of ideas and approaches is more than novel theorizing. It offers clinicians a new way forward." --Anthony Feinstein, MD, MPhil, PhD, FRCP University of Toronto To maintain the highest standards, allied health care practitioners must keep pace with evolving trends in diagnostics, interventions, and methodologies. This book supports clinicians by disseminating important perspectives, research, and procedures. It provides an integrative roadmap that fosters interdisciplinary cooperation. Key Features: Presents reviews of research on a broad selection of clinical disorders Includes a wide range of established and emerging diagnostic and intervention approaches Discusses viable evidence-based alternative treatment methods Critiques certain approaches, paradigms, and practices that may need to be revised Includes contributions from renowned psychologists, psychiatrists, and researchers Clinicians, researchers, and students will find this book a valuable source for interdisciplinary practice and research. It facilitates a sorely needed move toward integrative practice in an era in which specialization pervades.

Conflict of Interest in Medical Research, Education, and Practice

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Publisher : National Academies Press
ISBN 13 : 0309145449
Total Pages : 436 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Conflict of Interest in Medical Research, Education, and Practice by : Institute of Medicine

Download or read book Conflict of Interest in Medical Research, Education, and Practice written by Institute of Medicine and published by National Academies Press. This book was released on 2009-09-16 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collaborations of physicians and researchers with industry can provide valuable benefits to society, particularly in the translation of basic scientific discoveries to new therapies and products. Recent reports and news stories have, however, documented disturbing examples of relationships and practices that put at risk the integrity of medical research, the objectivity of professional education, the quality of patient care, the soundness of clinical practice guidelines, and the public's trust in medicine. Conflict of Interest in Medical Research, Education, and Practice provides a comprehensive look at conflict of interest in medicine. It offers principles to inform the design of policies to identify, limit, and manage conflicts of interest without damaging constructive collaboration with industry. It calls for both short-term actions and long-term commitments by institutions and individuals, including leaders of academic medical centers, professional societies, patient advocacy groups, government agencies, and drug, device, and pharmaceutical companies. Failure of the medical community to take convincing action on conflicts of interest invites additional legislative or regulatory measures that may be overly broad or unduly burdensome. Conflict of Interest in Medical Research, Education, and Practice makes several recommendations for strengthening conflict of interest policies and curbing relationships that create risks with little benefit. The book will serve as an invaluable resource for individuals and organizations committed to high ethical standards in all realms of medicine.

Pharmacogenomics An Introduction and Clinical Perspective

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Publisher : McGraw Hill Professional
ISBN 13 : 0071813713
Total Pages : 289 pages
Book Rating : 4.0/5 (718 download)

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Book Synopsis Pharmacogenomics An Introduction and Clinical Perspective by : Joseph S. Bertino

Download or read book Pharmacogenomics An Introduction and Clinical Perspective written by Joseph S. Bertino and published by McGraw Hill Professional. This book was released on 2012-10-12 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: A COMPLETE INTRODUCTORY TEXT TO THE FIELD OF PHARMACOGENOMICS The only pharmacogenomics resource to feature a global author team comprised of PharmDs, MDs, PhDs and social scientists, Pharmacogenomics offers an essential, highly accessible survey of this dynamic discipline. You will find thorough coverage of all need-to-know topics, from individual molecules to systemic diseases, plus an examination of the latest technologies that are constantly reshaping the field. Pharmacogenomics is cohesively organized into two sections, the first of which reviews basic aspects of pharmacogenomics, including ethics, regulatory, science, and drug metabolism, along with a "mini" course in molecular genetics and testing. The second section highlights the practical application of pharmacogenomics in cardiovascular medicine, immunology, neurology, and other specialties. FEATURES Important overview of general pharmacogenomics and pharmacogenetics concepts, including genetic variation in signal transduction and targets, plus a review of the genetic concepts of pharmacogenomics Discussion of regulatory considerations in pharmacogenomics Focus on the role of health care professionals along with a review of related privacy issues, as well as broader ethical, legal, and social considerations In-depth chapters on drug metabolism and transporters Practical, step-by-step guidance on public access to pharmacogenomic testing and patient counseling Up-to-date coverage of non-genetic influences on pharmacogenomics Emphasis on gene-drug interactions Numerous tables and figures Chapter-ending references Concise learning objectives at the beginning of each chapter Case studies to familiarize you with the clinical relevance of pharmacogenomics in each specialty