Parasites in the Tropic - A New Paradigm Shift

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Parasites in the Tropic - A New Paradigm Shift by :

Download or read book Parasites in the Tropic - A New Paradigm Shift written by and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Parasites in the Tropic - A New Paradigm Shift

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Publisher : Frontiers Media SA
ISBN 13 : 2889452085
Total Pages : 86 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Parasites in the Tropic - A New Paradigm Shift by : Veeranoot Nissapatorn

Download or read book Parasites in the Tropic - A New Paradigm Shift written by Veeranoot Nissapatorn and published by Frontiers Media SA. This book was released on 2017-07-06 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt: The highlight of this eBook is to bring new insights into parasites in the tropic. To achieve that, much has been discussed about risk assessment, infection rates, disease burden, hormones and mechanism of immune response, genetic expression and susceptibility as well as, therapeutic modalities. Authors raised hypothesis, discuss concepts, and show open questions. The remaining important issues to resolve questions within parasites in the tropic – a new paradigm shift are briefly discussed below. T. gondii, feline as the definitive host, is regarded as one of the most important parasites in the tropic. Human, as an accidental host, is the only species who still drinks raw milk or milk products particularly from animal sources. Based on the first paper, the author simplifies on how safe to drink milk to prevent the transmission of T. gondii by the insistence on heat treated milk before consumption. It is interesting to explore how hormone plays its role in Toxoplasma infection. Based on the second paper, the authors elucidated from thirty studies from humans, animals and cell cultures. Of these, it was shown that Toxoplasma infection was controlled by the presence of hormones found in different animal models. However, it is still premature to conclude which hormone that has a significant relationship with Toxoplasma infection. It estimates that one-third of the world population infected with T. gondii but the majority are asymptomatic. Based on the third paper, it demonstrated that people having low prevalent of Toxoplasma infection by having close contact with animals. This study will enhance positive attitudes for more people to be committed towards helping animals. For more than three decades, T. gondii has since been identified as one of the most important opportunistic parasitic pathogens in immunocompromised. Seroprevalence of chronic toxoplasmosis was detected in at least one-third of HIV-infected individuals in the regional hospital of southern Thailand, as reported from the fourth paper. Thailand has successfully formulated anti-retroviral therapy for HIV/AIDS patients and as a result reported a rare incidence of AIDS-related cerebral toxoplasmosis (CT) in this setting. Based on the fifth paper, the authors demonstrated low IL-10 (Th2 response) and IFN-γ (Th1 response) as well as high TNF-α were produced in ocular and cerebral toxoplasmosis in AIDS patients. This might be due to South American strains and/or the genetic susceptibility of the host. Due to high genetic diversity of T. gondii in Brazil, the sixth paper demonstrated that Calomys callosus survived chronically infected by T. gondii clonal type II strain and reinfected by Brazilian strains. However, congenital toxoplasmosis occurred leading to damaging effects of the developing fetus. The seventh paper conducted a questionnaire-based study on knowledge and practice on Toxoplasma infection among pregnant women from Malaysia, Philippines and Thailand. It clearly demonstrated that health education, a core value, is the cheapest and the best option to envisage the preventive strategies of feto-maternal toxoplasmosis from this region. For treatment modality of congenital toxoplasmosis, a novel experimental therapeutic synergism of diclazuril plus atovaquone combination shows a promising outcome with no toxicity in treating this condition, as demonstrated in the eighth paper. However, it warrants for future trials to prove its properties against T. gondii in different clinical scenarios of human toxoplasmosis for more effective therapeutic regimens. In the ninth paper, the author discussed the pathogenesis of maternal and congenital toxoplasmosis, the current treatment in clinical practice, and the experimental treatment approaches for promising future trials. Overall, this protozoan represents the most extraordinary example of parasite in the tropic and beyond scientific imagination. Hence, there are still many challenges ahead and waiting for more explorations on T. gondii, the parasite that never dies. Based on the findings from the tenth paper, it is interesting to identify common gene targets between Glossina p. gambiensis and Glossina m. morsitans that might shed some lights as a suitable candidate for controlling both acute and chronic forms of sleeping sickness. This therefore requires further investigations using proteomic analysis to ascertain the corresponding genes and its proteins as well as functional role that may help the search for more novel therapeutic agents.

The Stockholm Paradigm

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Publisher : University of Chicago Press
ISBN 13 : 022663258X
Total Pages : 423 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis The Stockholm Paradigm by : Daniel R. Brooks

Download or read book The Stockholm Paradigm written by Daniel R. Brooks and published by University of Chicago Press. This book was released on 2019-07-19 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.

PARADIGM SHIFT: MULTIDISCIPLINARY RESEARCH FOR A CHANGING WORLD, VOLUME-2

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Publisher : REDSHINE Publication
ISBN 13 : 9358090782
Total Pages : 283 pages
Book Rating : 4.3/5 (58 download)

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Book Synopsis PARADIGM SHIFT: MULTIDISCIPLINARY RESEARCH FOR A CHANGING WORLD, VOLUME-2 by : Dr. Sagarika Dash

Download or read book PARADIGM SHIFT: MULTIDISCIPLINARY RESEARCH FOR A CHANGING WORLD, VOLUME-2 written by Dr. Sagarika Dash and published by REDSHINE Publication. This book was released on 2024-08-31 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Avian Malaria and Related Parasites in the Tropics

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Publisher : Springer Nature
ISBN 13 : 3030516334
Total Pages : 575 pages
Book Rating : 4.0/5 (35 download)

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Book Synopsis Avian Malaria and Related Parasites in the Tropics by : Diego Santiago-Alarcon

Download or read book Avian Malaria and Related Parasites in the Tropics written by Diego Santiago-Alarcon and published by Springer Nature. This book was released on 2020-10-19 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Tropics are home to the greatest biodiversity in the world, but tropical species are at risk due to anthropogenic activities, mainly land use change, habitat loss, invasive species, and pathogens. Over the past 20 years, the avian malaria and related parasites (Order: Haemosporida) systems have received increased attention in the tropical regions from a diverse array of research perspectives. However, to date no attempts have been made to synthesize the available information and to propose new lines of research. This book provides such a synthesis by not only focusing on the antagonistic interactions, but also by providing conceptual chapters on topics going from avian haemosporidians life cycles and study techniques, to chapters addressing current concepts on ecology and evolution. For example, a chapter synthesizing basic biogeography and ecological niche model concepts is presented, followed by one on the island biogeography of avian haemosporidians. Accordingly, researchers and professionals interested in these antagonistic interaction systems will find both an overview of the field with special emphasis on the tropics, and access to the necessary conceptual framework for various topics in ecology, evolution and systematics. Given its conceptual perspective, the book will appeal not only to readers interested in avian haemosporidians, but also to those more generally interested in the ecology, evolution and systematics of host-parasite interactions.

Neuropeptide Systems as Targets for Parasite and Pest Control

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Publisher : Springer Science & Business Media
ISBN 13 : 1441969020
Total Pages : 246 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Neuropeptide Systems as Targets for Parasite and Pest Control by : Timothy G. Geary

Download or read book Neuropeptide Systems as Targets for Parasite and Pest Control written by Timothy G. Geary and published by Springer Science & Business Media. This book was released on 2011-01-13 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need to continually discover new agents for the control or treatment of invertebrate pests and pathogens is undeniable. Agriculture, both animal and plant, succeeds only to the extent that arthropod and helminth consumers, vectors and pathogens can be kept at bay. Humans and their companion animals are also plagued by invertebrate parasites. The deployment of chemical agents for these purposes inevitably elicits the selection of resistant populations of the targets of control, necessitating a regular introduction of new kinds of molecules. Experience in other areas of chemotherapy has shown that a thorough understanding of the biology of disease is an essential platform upon which to build a discovery program. Unfortunately, investment of research resources into understanding the basic physiology of invertebrates as a strategy to illuminate new molecular targets for pesticide and parasiticide discovery has been scarce, and the pace of introduction of new molecules for these indications has been slowed as a result. An exciting and so far unexploited area to explore in this regard is invertebrate neuropeptide physiology. This book was assembled to focus attention on this promising field by compiling a comprehensive review of recent research on neuropeptides in arthropods and helminths, with contributions from many of the leading laboratories working on these systems.

Parasitic Infections

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Publisher : John Wiley & Sons
ISBN 13 : 1119878020
Total Pages : 436 pages
Book Rating : 4.1/5 (198 download)

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Book Synopsis Parasitic Infections by : Abhay Prakash Mishra

Download or read book Parasitic Infections written by Abhay Prakash Mishra and published by John Wiley & Sons. This book was released on 2023-07-19 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Parasitic Infections Understand and defeat a scourge of public health with this cutting-edge guide Parasitic diseases are considered as an important public health problem due to the high morbidity and mortality rates, particularly in countries where climate and level of economic development create serious challenges to the creation of public health infrastructure, thus can make parasitic infections both graver and more difficult to contain. As we come to understand the global ramifications of public health, there has never been a more crucial time to understand these infections and the processes by which they can be managed and defeated. Parasitic Infections is a comprehensive overview of parasitic immunopathology, including the fundamentals of parasite biology, mechanisms and processes of infection, and the key steps of drug discovery and treatment. In addition to detailed coverage of the most commonly encountered infectious parasites, analysis of the immune system provides material pertinent to any possible parasitic infection. The result is an essential contribution to public health research. Parasitic Infections readers will also find: A careful balance of parasite immunopathology and pharmaceutical analysis Detailed discussion of parasites such as protozoans, helminths, and ectoparasites Case studies and in-depth analyses written by authors around the world on the basis of first hand investigation Parasitic Infections is a must-read for researchers or professionals in immunology, biology, medicinal chemistry, drug development or pharmaceutical research, and all related fields.

Blue Marble Health

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Publisher : JHU Press
ISBN 13 : 1421420465
Total Pages : 224 pages
Book Rating : 4.4/5 (214 download)

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Book Synopsis Blue Marble Health by : Peter J. Hotez

Download or read book Blue Marble Health written by Peter J. Hotez and published by JHU Press. This book was released on 2016-09 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do diseases of poverty afflict more people in wealthy countries than in the developing world? In 2011, Dr. Peter J. Hotez relocated to Houston to launch Baylor’s National School of Tropical Medicine. He was shocked to discover that a number of neglected diseases often associated with developing countries were widespread in impoverished Texas communities. Despite the United States’ economic prowess and first-world status, an estimated 12 million Americans living at the poverty level currently suffer from at least one neglected tropical disease, or NTD. Hotez concluded that the world’s neglected diseases—which include tuberculosis, hookworm infection, lymphatic filariasis, Chagas disease, and leishmaniasis—are born first and foremost of extreme poverty. In this book, Hotez describes a new global paradigm known as “blue marble health,” through which he asserts that poor people living in wealthy countries account for most of the world’s poverty-related illness. He explores the current state of neglected diseases in such disparate countries as Mexico, South Korea, Argentina, Australia, the United States, Japan, and Nigeria. By crafting public policy and relying on global partnerships to control or eliminate some of the world’s worst poverty-related illnesses, Hotez believes, it is possible to eliminate life-threatening disease while at the same time creating unprecedented opportunities for science and diplomacy. Clear, compassionate, and timely, Blue Marble Health is a must-read for leaders in global health, tropical medicine, and international development, along with anyone committed to helping the millions of people who are caught in the desperate cycle of poverty and disease.

Fundamentals of Tropical Freshwater Wetlands

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Publisher : Elsevier
ISBN 13 : 0128223634
Total Pages : 864 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Fundamentals of Tropical Freshwater Wetlands by : Tatenda Dalu

Download or read book Fundamentals of Tropical Freshwater Wetlands written by Tatenda Dalu and published by Elsevier. This book was released on 2021-11-25 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Tropical Freshwater Wetlands: From Ecology to Conservation Management is a practical guide and important tool for practitioners and educators interested in the ecology, conservation and management of wetlands in tropical/subtropical regions. The book is written in such a way that, in addition to scientists and managers, it is accessible to non-specialist readers. Organized into three themed sections and twenty-three chapters, this volume covers a variety of topics, exposing the reader to a full range of scientific, conservation and management issues. Each chapter has been written by specialists in the topic being presented. The book recognizes that wetland conservation, science and management are interlinked disciplines, and so it attempts to combine several perspectives to highlight the interdependence between the various professions that deal with issues in these environments. Within each chapter extensive cross-referencing is included, so as to help the reader link related aspects of the issues being discussed. - Contributed to by global experts in the field of tropical wetlands - Includes case studies and worked examples, enabling the reader to recreate the work already done - Focuses on tropical systems not available in any other book

Prevention and Control of Intestinal Parasitic Infections

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Publisher :
ISBN 13 :
Total Pages : 92 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Prevention and Control of Intestinal Parasitic Infections by : WHO Expert Committee on Prevention and Control of Intestinal Parasitic Infections

Download or read book Prevention and Control of Intestinal Parasitic Infections written by WHO Expert Committee on Prevention and Control of Intestinal Parasitic Infections and published by . This book was released on 1987 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Skin-Related Neglected Tropical Diseases (Skin-NTDs): A New Challenge

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Publisher : MDPI
ISBN 13 : 3039212532
Total Pages : 220 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Skin-Related Neglected Tropical Diseases (Skin-NTDs): A New Challenge by : Roderick J. Hay

Download or read book Skin-Related Neglected Tropical Diseases (Skin-NTDs): A New Challenge written by Roderick J. Hay and published by MDPI. This book was released on 2019-07-31 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue Skin-Related Neglected Tropical Diseases (Skin-NTDs)—A New Challenge that was published in TropicalMed

Control of Human Parasitic Diseases

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Publisher : Elsevier
ISBN 13 : 0080462944
Total Pages : 691 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Control of Human Parasitic Diseases by :

Download or read book Control of Human Parasitic Diseases written by and published by Elsevier. This book was released on 2007-03-23 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: Control of parasitic infections of humans has progressed rapidly over the last three decades. Such advances have resulted from focal disease control efforts based on historically effective interventions to new approaches to control following intensive research and pilot programs. Control of Human Parasitic Diseases focuses on the present state of control of the significant human parasitic infectious diseases. - Includes the impact of recent research findings on control strategy - Discusses the health policy implications of these findings and the importance of evaluation and monitoring - Highlights the lessons learned and the interactions between control programs and health systems

Tropical Forest Community Ecology

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Publisher : John Wiley & Sons
ISBN 13 : 1444356267
Total Pages : 686 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Tropical Forest Community Ecology by : Walter Carson

Download or read book Tropical Forest Community Ecology written by Walter Carson and published by John Wiley & Sons. This book was released on 2011-08-31 with total page 686 pages. Available in PDF, EPUB and Kindle. Book excerpt: Historically, tropical ecology has been a science often content with descriptive and demographic approaches, which is understandable given the difficulty of studying these ecosystems and the need for basic demographic information. Nonetheless, over the last several years, tropical ecologists have begun to test more sophisticated ecological theory and are now beginning to address a broad array of questions that are of particular importance to tropical systems, and ecology in general. Why are there are so many species in tropical forests and what mechanisms are responsible for the maintenance of that vast species diversity? What factors control species coexistence? Are there common patterns of species abundance and distribution across broad geographic scales? What is the role of trophic interactions in these complex ecosystems? How can these fragile ecosystems be conserved? Containing contributions from some of the world’s leading tropical ecologists, Tropical Forest Community Ecology provides a summary of the key issues in the discipline of tropical ecology: Includes contributions from some of the world’s leading tropical ecologists Covers patterns of species distribution, the maintenance of species diversity, the community ecology of tropical animals, forest regeneration and conservation of tropical ecosystems

The Problem South

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Publisher : University of Georgia Press
ISBN 13 : 0820342602
Total Pages : 352 pages
Book Rating : 4.8/5 (23 download)

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Book Synopsis The Problem South by : Natalie J. Ring

Download or read book The Problem South written by Natalie J. Ring and published by University of Georgia Press. This book was released on 2012 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: For most historians, the late nineteenth and early twentieth centuries saw the hostilities of the Civil War and the dashed hopes of Reconstruction give way to the nationalizing forces of cultural reunion, a process that is said to have downplayed sectional grievances and celebrated racial and industrial harmony. In truth, says Natalie J. Ring, this buoyant mythology competed with an equally powerful and far-reaching set of representations of the backward Problem South—one that shaped and reflected attempts by northern philanthropists, southern liberals, and federal experts to rehabilitate and reform the country's benighted region. Ring rewrites the history of sectional reconciliation and demonstrates how this group used the persuasive language of social science and regionalism to reconcile the paradox of poverty and progress by suggesting that the region was moving through an evolutionary period of “readjustment” toward a more perfect state of civilization. In addition, The Problem South contends that the transformation of the region into a mission field and laboratory for social change took place in a transnational moment of reform. Ambitious efforts to improve the economic welfare of the southern farmer, eradicate such diseases as malaria and hookworm, educate the southern populace, “uplift” poor whites, and solve the brewing “race problem” mirrored the colonial problems vexing the architects of empire around the globe. It was no coincidence, Ring argues, that the regulatory state's efforts to solve the “southern problem” and reformers' increasing reliance on social scientific methodology occurred during the height of U.S. imperial expansion.

Neglected Tropical Diseases - Sub-Saharan Africa

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Publisher : Springer
ISBN 13 : 3319254715
Total Pages : 421 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Neglected Tropical Diseases - Sub-Saharan Africa by : John Gyapong

Download or read book Neglected Tropical Diseases - Sub-Saharan Africa written by John Gyapong and published by Springer. This book was released on 2016-01-13 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview on the major neglected tropical diseases (NTDs) occurring in Sub-Saharan Africa, such as Leishmaniasis, Buruli Ulcer and Schistosomiasis. In well-structured chapters epidemiology and biology of these parasitic diseases will be discussed in detail. Further, diagnostics and therapeutic approaches as well as prevention strategies will be reviewed. The book will be of interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of the Sub-Saharan region.

Parasite and Disease Spread by Major Rivers on Earth

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Publisher : Springer Nature
ISBN 13 : 3030290611
Total Pages : 454 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Parasite and Disease Spread by Major Rivers on Earth by : Heinz Mehlhorn

Download or read book Parasite and Disease Spread by Major Rivers on Earth written by Heinz Mehlhorn and published by Springer Nature. This book was released on 2019-11-12 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on waterborne pathogens and significant diseases occurring along major rivers around the globe, including key examples like the Amazonas, Mekong River and Nile. Written by leading international experts, it offers unique insights into local riverine infection risks in times of global warming, and addressing these through advances in diagnosis, health management and the development of simple but effective control measures. It also sheds light on why former societies collapsed due to transmitted diseases during periods of climate change, droughts and floods, to help establish effective preventive measures for the future. The book appeals to a wide readership, from scientists in the field of parasitology, infectious diseases and epidemiology, to healthcare managers and general readers with an interest in pathogen spread along the largest rivers on earth. It particularly highlights past and current control mechanisms in times of global warming and assesses potential future health hazards.

Investing to Overcome the Global Impact of Neglected Tropical Diseases

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Publisher : World Health Organization
ISBN 13 : 9241564865
Total Pages : 211 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Investing to Overcome the Global Impact of Neglected Tropical Diseases by : World Health Organization

Download or read book Investing to Overcome the Global Impact of Neglected Tropical Diseases written by World Health Organization and published by World Health Organization. This book was released on 2015-08-05 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.