The Stockholm Paradigm

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Publisher : University of Chicago Press
ISBN 13 : 022663258X
Total Pages : 423 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis The Stockholm Paradigm by : Daniel R. Brooks

Download or read book The Stockholm Paradigm written by Daniel R. Brooks and published by University of Chicago Press. This book was released on 2019-07-19 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.

The Stockholm Paradigm

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Author :
Publisher : University of Chicago Press
ISBN 13 : 022663244X
Total Pages : 423 pages
Book Rating : 4.2/5 (266 download)

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Book Synopsis The Stockholm Paradigm by : Daniel R. Brooks

Download or read book The Stockholm Paradigm written by Daniel R. Brooks and published by University of Chicago Press. This book was released on 2019-07-16 with total page 423 pages. Available in PDF, EPUB and Kindle. Book excerpt: The contemporary crisis of emerging disease has been a century and a half in the making. Human, veterinary, and crop health practitioners convinced themselves that disease could be controlled by medicating the sick, vaccinating those at risk, and eradicating the parts of the biosphere responsible for disease transmission. Evolutionary biologists assured themselves that coevolution between pathogens and hosts provided a firewall against disease emergence in new hosts. Most climate scientists made no connection between climate changes and disease. None of these traditional perspectives anticipated the onslaught of emerging infectious diseases confronting humanity today. As this book reveals, a new understanding of the evolution of pathogen-host systems, called the Stockholm Paradigm, explains what is happening. The planet is a minefield of pathogens with preexisting capacities to infect susceptible but unexposed hosts, needing only the opportunity for contact. Climate change has always been the major catalyst for such new opportunities, because it disrupts local ecosystem structure and allows pathogens and hosts to move. Once pathogens expand to new hosts, novel variants may emerge, each with new infection capacities. Mathematical models and real-world examples uniformly support these ideas. Emerging disease is thus one of the greatest climate change–related threats confronting humanity. Even without deadly global catastrophes on the scale of the 1918 Spanish Influenza pandemic, emerging diseases cost humanity more than a trillion dollars per year in treatment and lost productivity. But while time is short, the danger is great, and we are largely unprepared, the Stockholm Paradigm offers hope for managing the crisis. By using the DAMA (document, assess, monitor, act) protocol, we can “anticipate to mitigate” emerging disease, buying time and saving money while we search for more effective ways to cope with this challenge.

A Funny Thing Happened on the Way to Stockholm

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1643136399
Total Pages : 304 pages
Book Rating : 4.6/5 (431 download)

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Book Synopsis A Funny Thing Happened on the Way to Stockholm by : Robert Lefkowitz

Download or read book A Funny Thing Happened on the Way to Stockholm written by Robert Lefkowitz and published by Simon and Schuster. This book was released on 2021-02-02 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rollicking memoir from the cardiologist turned legendary scientist and winner of the Nobel Prize that revels in the joy of science and discovery. Like Richard Feynman in the field of physics, Dr. Robert Lefkowitz is also known for being a larger-than-life character: a not-immodest, often self-deprecating, always entertaining raconteur. Indeed, when he received the Nobel Prize, the press corps in Sweden covered him intensively, describing him as “the happiest Laureate.” In addition to his time as a physician, from being a "yellow beret" in the public health corps with Dr. Anthony Fauci to his time as a cardiologist, and his extraordinary transition to biochemistry, which would lead to his Nobel Prize win, Dr. Lefkowitz has ignited passion and curiosity as a fabled mentor and teacher. But it's all in a days work, as Lefkowitz reveals in A Funny Thing Happened on the Way to Stockholm, which is filled to the brim with anecdotes and energy, and gives us a glimpse into the life of one of today's leading scientists.

Mobile Virtual Work

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Publisher : Springer Science & Business Media
ISBN 13 : 354028365X
Total Pages : 392 pages
Book Rating : 4.5/5 (42 download)

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Book Synopsis Mobile Virtual Work by : J.H. Erik Andriessen

Download or read book Mobile Virtual Work written by J.H. Erik Andriessen and published by Springer Science & Business Media. This book was released on 2005-12-27 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dear Reader This is a book about mobile virtual work. It aims at clarifying the basic concepts and showing present practices and future challenges. The roots of the book are in the collaboration of few European practitioners and - searchers, who met each other under the umbrella of the Swedish SALTSA programme (see next page) in January 2002 in Stockholm. The group was first called ‘ICT, Mobility and Work Organisation’ but redefined itself quickly as ‘Mobile Virtual Cooperative Work’ group. The change of the name reflects the development of reasoning in the group. We could not find much material on mobile work, certainly not systematic studies, - though a growing interest in mobile technologies and services could be found. Practices of telework and virtual organizations were better known, but we were convinced that the combination with mobile work was so- thing different and new. Our main target became to understand what it was all about. The next step was an expert meeting in October 2004 at Rånäs Castle again in Sweden. A wider group of experts was invited to present their views on mobile virtual work and ideas about book chapters from different perspectives of working life. Some of the expertise could be found through the network of the AMI@Work family created by the New Working En- ronments unit of the European Commission’s Information Society Dir- torate-General. Also close collaboration was developed with the related MOSAIC program.

The Blueprint

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Author :
Publisher : Daniel Rirdan
ISBN 13 : 1470135884
Total Pages : 495 pages
Book Rating : 4.4/5 (71 download)

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Book Synopsis The Blueprint by : Daniel Rirdan

Download or read book The Blueprint written by Daniel Rirdan and published by Daniel Rirdan. This book was released on 2012 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: From climate change to land degradation to fossil fuel shortages, we are faced with an impending calamity that threatens to bankrupt the planetary ecosystem and with it much of the manmade world. This book offers a plan that truly goes the distance: a highly detailed, planetary-wide blueprint that lays out a new course for our technological and industrial engines. It calls for sweeping adjustments in the way every person thinks and lives.--Inside front cover.

Rethinking Cancer

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Publisher : MIT Press
ISBN 13 : 0262045214
Total Pages : 433 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis Rethinking Cancer by : Bernhard Strauss

Download or read book Rethinking Cancer written by Bernhard Strauss and published by MIT Press. This book was released on 2021-04-27 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading scientists argue for a new paradigm for cancer research, proposing a complex systems view of cancer supported by empirical evidence. Current consensus in cancer research explains cancer as a disease caused by specific mutations in certain genes. After dramatic advances in genome sequencing, never before have we known so much about the individual cancer cell--and yet never before has it been so unclear what to do with this knowledge. In this volume, leading researchers argue for a new theory framework for understanding and treating cancer. The contributors propose a complex systems view of cancer, presenting conceptual building blocks for a new research paradigm supported by empirical evidence. The contributors first discuss the new research framework in terms of theoretical foundations and then take up the relevance of a systems approach, reviewing such topics as nonlinearity, recurrence after treatment, the cellular attractor concept, network theory, and non-coding DNA--the "dark matter" of our genome. They address the temporality of cancer progression, drawing on evolutionary theory and clinical experience. Finally, they cover the dominant role of the tissue microenvironment in cancer, analyzing topics including altered metabolic pathways, the disease-defining influence on metastasis, and the interconnectedness of different environmental niches across levels of organization.

The Atrocity Paradigm

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Author :
Publisher : Oxford University Press
ISBN 13 : 0199881790
Total Pages : 304 pages
Book Rating : 4.1/5 (998 download)

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Book Synopsis The Atrocity Paradigm by : Claudia Card

Download or read book The Atrocity Paradigm written by Claudia Card and published by Oxford University Press. This book was released on 2002-09-12 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: What distinguishes evils from ordinary wrongs? Is hatred a necessarily evil? Are some evils unforgivable? Are there evils we should tolerate? What can make evils hard to recognize? Are evils inevitable? How can we best respond to and live with evils? Claudia Card offers a secular theory of evil that responds to these questions and more. Evils, according to her theory, have two fundamental components. One component is reasonably foreseeable intolerable harm -- harm that makes a life indecent and impossible or that makes a death indecent. The other component is culpable wrongdoing. Atrocities, such as genocides, slavery, war rape, torture, and severe child abuse, are Cards paradigms because in them these key elements are writ large. Atrocities deserve more attention than secular philosophers have so far paid them. They are distinguished from ordinary wrongs not by the psychological states of evildoers but by the seriousness of the harm that is done. Evildoers need not be sadistic:they may simply be negligent or unscrupulous in pursuing their goals. Cards theory represents a compromise between classic utilitarian and stoic alternatives (including Kants theory of radical evil). Utilitarians tend to reduce evils to their harms; Stoics tend to reduce evils to the wickedness of perpetrators: Card accepts neither reduction. She also responds to Nietzsches challenges about the worth of the concept of evil, and she uses her theory to argue that evils are more important than merely unjust inequalities. She applies the theory in explorations of war rape and violence against intimates. She also takes up what Primo Levi called the gray zone, where victims become complicit in perpetrating on others evils that threaten to engulf themselves. While most past accounts of evil have focused on perpetrators, Card begins instead from the position of the victims, but then considers more generally how to respond to -- and live with -- evils, as victims, as perpetrators, and as those who have become both.

Loving to Survive

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Author :
Publisher : NYU Press
ISBN 13 : 0814738540
Total Pages : 346 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Loving to Survive by : Dee L.R. Graham

Download or read book Loving to Survive written by Dee L.R. Graham and published by NYU Press. This book was released on 1995-07-01 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: Have you wondered: Why women are more sympathetic than men toward O. J. Simpson? Why women were no more supportive of the Equal Rights Amendment than men? Why women are no more likely than men to support a female political candidate? Why women are no more likely than men to embrace feminism--a movement by, about, and for women? Why some women stay with men who abuse them? Loving to Survive addresses just these issues and poses a surprising answer. Likening women's situation to that of hostages, Dee L. R. Graham and her co- authors argue that women bond with men and adopt men's perspective in an effort to escape the threat of men's violence against them. Dee Graham's announcement, in 1991, of her research on male-female bonding was immediately followed by a national firestorm of media interest. Her startling and provocative conclusion was covered in dozens of national newspapers and heatedly debated. In Loving to Survive, Graham provides us with a complete account of her remarkable insights into relationships between men and women. In 1973, three women and one man were held hostage in one of the largest banks in Stockholm by two ex-convicts. These two men threatened their lives, but also showed them kindness. Over the course of the long ordeal, the hostages came to identify with their captors, developing an emotional bond with them. They began to perceive the police, their prospective liberators, as their enemies, and their captors as their friends, as a source of security. This seemingly bizarre reaction to captivity, in which the hostages and captors mutually bond to one another, has been documented in other cases as well, and has become widely known as Stockholm Syndrome. The authors of this book take this syndrome as their starting point to develop a new way of looking at male-female relationships. Loving to Survive considers men's violence against women as crucial to understanding women's current psychology. Men's violence creates ever-present, and therefore often unrecognized, terror in women. This terror is often experienced as a fear for any woman of rape by any man or as a fear of making any man angry. They propose that women's current psychology is actually a psychology of women under conditions of captivitythat is, under conditions of terror caused by male violence against women. Therefore, women's responses to men, and to male violence, resemble hostages' responses to captors. Loving to Survive explores women's bonding to men as it relates to men's violence against women. It proposes that, like hostages who work to placate their captors lest they kill them, women work to please men, and from this springs women's femininity. Femininity describes a set of behaviors that please men because they communicate a woman's acceptance of her subordinate status. Thus, feminine behaviors are, in essence, survival strategies. Like hostages who bond to their captors, women bond to men in an effort to survive. This is a book that will forever change the way we look at male-female relationships and women's lives.

Big World, Small Planet

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Author :
Publisher : Yale University Press
ISBN 13 : 0300218362
Total Pages : 208 pages
Book Rating : 4.3/5 (2 download)

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Book Synopsis Big World, Small Planet by : Johan Rockstrom

Download or read book Big World, Small Planet written by Johan Rockstrom and published by Yale University Press. This book was released on 2015-01-01 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: We have entered the Anthropocene - the era of massive human impacts on the planet - and the actions of over seven billion residents threaten to destabilize Earth's natural systems, with consequences for human societies. The authors combine the latest science with storytelling and photography to create a new narrative for humanity's future and reject the notion that economic growth and human prosperity can only be achieved at the expense of the environment

Remarkable Creatures

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Publisher : HMH
ISBN 13 : 0547526148
Total Pages : 357 pages
Book Rating : 4.5/5 (475 download)

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Book Synopsis Remarkable Creatures by : Sean B. Carroll

Download or read book Remarkable Creatures written by Sean B. Carroll and published by HMH. This book was released on 2014-10-16 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: National Book Award Finalist: A biologist’s “thoroughly enjoyable” account of the expeditions that unearthed the history of life on our planet (Publishers Weekly). Not so long ago, most of our world was an unexplored wilderness. Our sense of its age was vague and vastly off the mark, and much of the knowledge of our own species’ history was a set of fantastic myths and fairy tales. But scientists were about to embark on an amazing new era of understanding. From the New York Times–bestselling author of The Big Picture, this book leads us on a rousing voyage that recounts the most important discoveries in two centuries of natural history: from Darwin’s trip around the world to Charles Walcott’s discovery of pre-Cambrian life in the Grand Canyon; from Louis and Mary Leakey’s investigation of our deepest past in East Africa to the trailblazers in modern laboratories who have located a time clock in our DNA. Filled with the same sense of adventure that spurred on these extraordinary men and women, Remarkable Creatures is a “stirring introduction to the wonder of evolutionary biology” (Kirkus Reviews). “Charming and enlightening.” —San Francisco Chronicle “As fast-paced as a detective story.” —Nature

String Theory and the Scientific Method

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Publisher : Cambridge University Press
ISBN 13 : 1107067588
Total Pages : pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis String Theory and the Scientific Method by : Richard Dawid

Download or read book String Theory and the Scientific Method written by Richard Dawid and published by Cambridge University Press. This book was released on 2013-05-02 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: String theory has played a highly influential role in theoretical physics for nearly three decades and has substantially altered our view of the elementary building principles of the Universe. However, the theory remains empirically unconfirmed, and is expected to remain so for the foreseeable future. So why do string theorists have such a strong belief in their theory? This book explores this question, offering a novel insight into the nature of theory assessment itself. Dawid approaches the topic from a unique position, having extensive experience in both philosophy and high-energy physics. He argues that string theory is just the most conspicuous example of a number of theories in high-energy physics where non-empirical theory assessment has an important part to play. Aimed at physicists and philosophers of science, the book does not use mathematical formalism and explains most technical terms.

Case Theory in Business and Management

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Publisher : SAGE
ISBN 13 : 1473926823
Total Pages : 441 pages
Book Rating : 4.4/5 (739 download)

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Book Synopsis Case Theory in Business and Management by : Evert Gummesson

Download or read book Case Theory in Business and Management written by Evert Gummesson and published by SAGE. This book was released on 2017-01-25 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: ′This meticulous book submits research and the research process to deep scrutiny. It debunks the unhelpful dichotomy between quantitative and qualitative research and highlights the great value of multi-method and interactive research, approaches that have greatly deepened our thinking.′ – Professor Adrian Payne, University of New South Wales, Australia / Professor Pennie Frow, University of Sydney Setting out to dispel the argument that case study research lacks the science, theory and therefore validity of other forms of research, Evert Gummesson combines many decades of experience as both a renowned scholar and a reflective practitioner to effectively bridge the divide between case theory and how it is applied in practice. Bringing the fundamental strengths of cases to the fore, Gummesson introduces the ′Case Theory′ concept as an expanded version of case study research which includes both methodology and the types of results that emerge by: Guiding the reader in the theoretical and philosophical underpinning Demonstrating how to translate theory to pertinent research practice that address the real and consequential issues in business and management today. This book will appeal to students, academics and researchers who are interested in the science and philosophy behind case study research as well as the methodology and a thought-provoking read for anyone who wants to be challenged about their belief of case study theory.

Suppletion in Verb Paradigms

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Publisher : John Benjamins Publishing
ISBN 13 : 9027229791
Total Pages : 256 pages
Book Rating : 4.0/5 (272 download)

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Book Synopsis Suppletion in Verb Paradigms by : Ljuba N. Veselinova

Download or read book Suppletion in Verb Paradigms written by Ljuba N. Veselinova and published by John Benjamins Publishing. This book was released on 2006 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines stem change in verb paradigms, as in English go 'go.PRESENT' vs. went 'go.PAST', a phenomenon referred to as suppletion in current linguistic theory. The work is based on a broad sample of 193 languages, and examines this long neglected phenomenon from a typological perspective. In addition to identifying types of suppletion which occur cross-linguistically, the study brings to light areal patterns of the occurrence of suppletive forms in verb paradigms. Several hypotheses as regards the diachronic development of suppletive forms are presented as well. The author also seeks to explore the methodological issues of evaluating the frequency of linguistic features in large language samples by introducing a method of weighting languages according to their genetic relatedness. All figures obtained in this way are compared to the proportions yielded by more familiar counting methods, and the results and implications of the different procedures are compared and discussed throughout.

Creolizing Political Theory

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Author :
Publisher : Fordham Univ Press
ISBN 13 : 0823254836
Total Pages : 312 pages
Book Rating : 4.8/5 (232 download)

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Book Synopsis Creolizing Political Theory by : Jane Anna Gordon

Download or read book Creolizing Political Theory written by Jane Anna Gordon and published by Fordham Univ Press. This book was released on 2014-02-03 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Might creolization offer political theory an approach that would better reflect the heterogeneity of political life? After all, it describes mixtures that were not supposed to have emerged in the plantation societies of the Caribbean but did so through their capacity to exemplify living culture, thought, and political practice. Similar processes continue today, when people who once were strangers find themselves unequal co-occupants of new political locations they both seek to call “home.” Unlike multiculturalism, in which different cultures are thought to co-exist relatively separately, creolization describes how people reinterpret themselves through interaction with one another. While indebted to comparative political theory, Gordon offers a critique of comparison by demonstrating the generative capacity of creolizing methodologies. She does so by bringing together the eighteenth-century revolutionary Swiss thinker Jean-Jacques Rousseau and the twentieth-century Martinican-born Algerian liberationist Frantz Fanon. While both provocatively challenged whether we can study the world in ways that do not duplicate the prejudices that sustain its inequalities, Fanon, she argues, outlined a vision of how to bring into being the democratically legitimate alternatives that Rousseau mainly imagined.

Adaptation in Metapopulations

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Publisher : University of Chicago Press
ISBN 13 : 022612973X
Total Pages : 269 pages
Book Rating : 4.2/5 (261 download)

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Book Synopsis Adaptation in Metapopulations by : Michael J. Wade

Download or read book Adaptation in Metapopulations written by Michael J. Wade and published by University of Chicago Press. This book was released on 2016-05-03 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Across the globe, populations of plants and animals live in clusters, but maintain a connectivity a population of populations. There are naturally occurring metapopulations, such as clusters of groupers spread across coral reefs, and there are metapopulations humans have helped create by fragmenting landscapes: stands of trees separated by roads, prairies separated by agricultural farms. As the dynamics of landscape change have accelerated, and understanding of how metapopulations functions has played a critical role in ecology and evolutionary biology. Adaptation in Metapopulations synthesizes the role of genetic interactions in adaptive evolution and their influence on the effectiveness of different types of selection. Drawing on extensive field work and lab experiments, cohered with a strong conceptual arc, the work also integrates molecular and organismal biology, as Wade explores adaptation at multiple scales, and shows how evolutionary dynamics scale from the gene to the metapopulation. "

Governing Climate Change

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Publisher : Cambridge University Press
ISBN 13 : 1108304745
Total Pages : pages
Book Rating : 4.1/5 (83 download)

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Book Synopsis Governing Climate Change by : Andrew Jordan

Download or read book Governing Climate Change written by Andrew Jordan and published by Cambridge University Press. This book was released on 2018-04-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Climate change governance is in a state of enormous flux. New and more dynamic forms of governing are appearing around the international climate regime centred on the United Nations Framework Convention on Climate Change (UNFCCC). They appear to be emerging spontaneously from the bottom up, producing a more dispersed pattern of governing, which Nobel Laureate Elinor Ostrom famously described as 'polycentric'. This book brings together contributions from some of the world's foremost experts to provide the first systematic test of the ability of polycentric thinking to explain and enhance societal attempts to govern climate change. It is ideal for researchers in public policy, international relations, environmental science, environmental management, politics, law and public administration. It will also be useful on advanced courses in climate policy and governance, and for practitioners seeking incisive summaries of developments in particular sub-areas and sectors. This title is also available as Open Access on Cambridge Core.

Handbook of Creative Cities

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Author :
Publisher : Edward Elgar Publishing
ISBN 13 : 0857936395
Total Pages : 575 pages
Book Rating : 4.8/5 (579 download)

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Book Synopsis Handbook of Creative Cities by : D. E. Andersson

Download or read book Handbook of Creative Cities written by D. E. Andersson and published by Edward Elgar Publishing. This book was released on 2011-01-01 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the publication of The Rise of the Creative Class by Richard Florida in 2002, the 'creative city' became the new hot topic among urban policymakers, planners and economists. Florida has developed one of three path-breaking theories about the relationship between creative individuals and urban environments. The economist Åke E. Andersson and the psychologist Dean Simonton are the other members of this 'creative troika'. In the Handbook of Creative Cities, Florida, Andersson and Simonton appear in the same volume for the first time. The expert contributors in this timely Handbook extend their insights with a varied set of theoretical and empirical tools. The diversity of the contributions reflect the multidisciplinary nature of creative city theorizing, which encompasses urban economics, economic geography, social psychology, urban sociology, and urban planning. The stated policy implications are equally diverse, ranging from libertarian to social democratic visions of our shared creative and urban future. Being truly international in its scope, this major Handbook will be particularly useful for policy makers that are involved in urban development, academics in urban economics, economic geography, urban sociology, social psychology, and urban planning, as well as graduate and advanced undergraduate students across the social sciences and in business.