Pain Models

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Animal Models of Pain

Author : Chao Ma
Publisher : Humana Press
ISBN 13 : 9781607618799
Total Pages : 0 pages
Book Rating : 4.6/5 (187 download)

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Book Synopsis Animal Models of Pain by : Chao Ma

Download or read book Animal Models of Pain written by Chao Ma and published by Humana Press. This book was released on 2010-10-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the loss of work days, the price of health care and payments for compensation, litigation, and malpractice, and the overwhelming cost of human suffering, chronic pain syndromes affect humanity enormously on both an economic and personal level. In Animal Models of Pain, expert investigators in the field provide a consolidated review of the current state of pain research by capturing the diversity of animal models that are used to investigate pain mechanisms, which range from surgical incision to mechanical compression and from spinal cord injury to cutaneous/local inflammation and beyond. As a volume in the respected Neuromethods series, this book delivers its vital content through detailed descriptions of a wide variety of step-by-step laboratory methods. Authoritative and cutting-edge, Animal Models of Pain seeks to lead scientists closer to the ultimate goal of improving the quality of life and relieving the unbearable burden of chronic pain for millions of people throughout the world.

Pain Models

Author : Hermann O. Handwerker
Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1496331931
Total Pages : 663 pages
Book Rating : 4.4/5 (963 download)

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Book Synopsis Pain Models by : Hermann O. Handwerker

Download or read book Pain Models written by Hermann O. Handwerker and published by Lippincott Williams & Wilkins. This book was released on 2015-06-01 with total page 663 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neurobiology and mechanisms discovered in animals often do not translate to patients with a chronic pain condition. To help researchers and clinicians develop and use models that can help translate data from animals into humans, this book presents experimental animal models, with a focus on how they may translate into humans human experimental pain models, including details about pain induction and assessment human surrogate pain models clinical applications of pain models models that may link mechanisms of pain and pruritus Pain Models contains 29 chapters by internationally recognized experts. It is a comprehensive survey of pain models at different levels, and commentaries by clinicians directly address clinical perspectives. This unique book is unprecedented in its content. It's a quick reminder of the hard work needed to investigate the complex issue of pain perception. With the advent of increasingly sensitive noninvasive investigational tools, the authors want readers to know that basic research is still needed to help develop new drugs. This book will enrich anyone who wishes to know all that goes into conducting pain research with a lab-based pain model.

Translational Pain Research

Author : Lawrence Kruger
Publisher : CRC Press
ISBN 13 : 1439812101
Total Pages : 458 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Translational Pain Research by : Lawrence Kruger

Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical

Relieving Pain in America

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 030921484X
Total Pages : 383 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Relieving Pain in America by : Institute of Medicine

Download or read book Relieving Pain in America written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-26 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

Animal Models of Pain

Author : Chao Ma
Publisher : Humana Press
ISBN 13 : 9781493957613
Total Pages : 204 pages
Book Rating : 4.9/5 (576 download)

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Book Synopsis Animal Models of Pain by : Chao Ma

Download or read book Animal Models of Pain written by Chao Ma and published by Humana Press. This book was released on 2016-08-23 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the loss of work days, the price of health care and payments for compensation, litigation, and malpractice, and the overwhelming cost of human suffering, chronic pain syndromes affect humanity enormously on both an economic and personal level. In Animal Models of Pain, expert investigators in the field provide a consolidated review of the current state of pain research by capturing the diversity of animal models that are used to investigate pain mechanisms, which range from surgical incision to mechanical compression and from spinal cord injury to cutaneous/local inflammation and beyond. As a volume in the respected Neuromethods series, this book delivers its vital content through detailed descriptions of a wide variety of step-by-step laboratory methods. Authoritative and cutting-edge, Animal Models of Pain seeks to lead scientists closer to the ultimate goal of improving the quality of life and relieving the unbearable burden of chronic pain for millions of people throughout the world.

Verification of Animal Pain Models by Reverse Translation

Author : Robert M. Caudle
Publisher : Frontiers Media SA
ISBN 13 : 2889718018
Total Pages : 135 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Verification of Animal Pain Models by Reverse Translation by : Robert M. Caudle

Download or read book Verification of Animal Pain Models by Reverse Translation written by Robert M. Caudle and published by Frontiers Media SA. This book was released on 2021-12-06 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Oxford Textbook of Pediatric Pain

Author : Bonnie J. Stevens
Publisher : Oxford University Press
ISBN 13 : 0198818769
Total Pages : 713 pages
Book Rating : 4.1/5 (988 download)

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Book Synopsis Oxford Textbook of Pediatric Pain by : Bonnie J. Stevens

Download or read book Oxford Textbook of Pediatric Pain written by Bonnie J. Stevens and published by Oxford University Press. This book was released on 2021 with total page 713 pages. Available in PDF, EPUB and Kindle. Book excerpt: The oxford textbook of paediatric pain brings together clinicians, educators, trainees and researchers to provide an authoritative resource on all aspects of pain in infants, children and youth.

Methods in Pain Research

Author : Lawrence Kruger
Publisher : CRC Press
ISBN 13 : 1420042564
Total Pages : 338 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Methods in Pain Research by : Lawrence Kruger

Download or read book Methods in Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2001-06-22 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past two decades, pain research has become one of the most rapidly growing areas of neuroscience activity. Methods in Pain Research brings together in a single volume a survey of the methods that can be used to study a reaction or 'sensory report' in humans that can only be inferred by indirect means in animal or tissues studies. It presents

Neuropathic Pain

Author : Cory Toth
Publisher : Cambridge University Press
ISBN 13 : 1107470439
Total Pages : 385 pages
Book Rating : 4.1/5 (74 download)

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Book Synopsis Neuropathic Pain by : Cory Toth

Download or read book Neuropathic Pain written by Cory Toth and published by Cambridge University Press. This book was released on 2013-11-07 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Central or peripheral neuropathic pain can be caused by a wide range of injuries, infections and diseases such as: spinal cord injury, multiple sclerosis, stroke, herpes zoster, diabetes and cancer. Many of these pain syndromes are difficult to treat, representing a challenge for many neurologists not routinely trained in pain management. Written by an international team of experts in the field, Neuropathic Pain: Causes, Management and Understanding gives readers an in-depth understanding of the multitude of conditions causing neuropathic pain. Epidemiology, clinical diagnosis, pathophysiology, outcome measurement and the best evidence-based management of individual and general neuropathic pain conditions are also described in depth. A unique chapter, written from a patient's viewpoint, gives new insight into how chronic neuropathic pain affects the lives of those patients with the condition. This book is essential reading for all pain specialists, neurologists, psychiatrists and anesthesiologists who wish to better understand their patients' neuropathic pain.

Spinal Cord Injury Pain

Author : Christine N. Sang
Publisher : Elsevier
ISBN 13 : 0128186631
Total Pages : 510 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Spinal Cord Injury Pain by : Christine N. Sang

Download or read book Spinal Cord Injury Pain written by Christine N. Sang and published by Elsevier. This book was released on 2021-10-21 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spinal Cord Injury Pain presents the basis for preclinical and clinical investigations, along with strategies for new approaches in the treatment of central neuropathic pain. Contributors from the private sector and academia provide a comprehensive review of state-of-the-art research in this challenging space. Topics include Epidemiology of Chronic Pain Following SCI, experimental models and mechanisms of chronic pain in SCI, and new targets and technologies. This book serves as a resource for continued translational research that will result in novel approaches and treatments that improve function and quality of life for individuals with CNP/SCI. Despite a better understanding of the complexity of mechanisms of CNP/SCI, improved medical and surgical management of SCI, and the subsequent acceleration of the identification of new targets and the development of novel analgesics, there is still a great unmet clinical need in the area of CNP following SCI. Hence, this book is a welcomed addition to current research and developments. Provides a comprehensive resource for novel approaches and treatments that improve function and quality of life for individuals with CNP/SCI Includes contributors from the private sector and academia Covers epidemiology of chronic pain following SCI, experimental models, mechanisms of chronic pain in SCI, and new targets and technologies

The Routledge Handbook of Philosophy of Pain

Author : Jennifer Corns
Publisher : Taylor & Francis
ISBN 13 : 1317585461
Total Pages : 477 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis The Routledge Handbook of Philosophy of Pain by : Jennifer Corns

Download or read book The Routledge Handbook of Philosophy of Pain written by Jennifer Corns and published by Taylor & Francis. This book was released on 2017-07-14 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: The phenomenon of pain presents problems and puzzles for philosophers who want to understand its nature. Though pain might seem simple, there has been disagreement since Aristotle about whether pain is an emotion, sensation, perception, or disturbed state of the body. Despite advances in psychology, neuroscience, and medicine, pain is still poorly understood and multiple theories of pain abound. The Routledge Handbook of Philosophy of Pain is an outstanding reference source to the key topics, problems, and debates in this exciting and interdisciplinary subject and is the first collection of its kind. Comprising over thirty chapters by a team of international contributors the Handbook is divided into nine clear parts: Modeling pain in philosophy Modeling pain in neuroscience Modeling pain in psychology Pain in philosophy of mind Pain in epistemology Pain in philosophy of religion Pain in ethics Pain in medicine Pain in law As well as fundamental topics in the philosophy of pain such as the nature, role, and value of pain, many other important topics are covered including the neurological pathways involved in pain processing; biopsychosocial and cognitive-behavioural models of pain; chronic pain; pain and non-human animals; pain and knowledge; controlled substances for pain; pain and placebo effects; and pain and physician-assisted suicide. The Routledge Handbook of Philosophy of Pain is essential reading for students and researchers in philosophy of mind, philosophy of psychology and ethics. It will also be very useful to researchers of pain from any field, especially those in psychology, medicine, and health studies.

Cytokines and Pain

Author : L.R. Watkins
Publisher : Springer
ISBN 13 : 3034887493
Total Pages : 248 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis Cytokines and Pain by : L.R. Watkins

Download or read book Cytokines and Pain written by L.R. Watkins and published by Springer. This book was released on 2013-03-08 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation has on pain modulation. The purpose of this book is to examine, for the first time, immune-to-brain communication from the viewpoint of its effect on pain processing. It is aimed both at the basic scientist and health care providers, in order to clarify the major role that substances released by immune cells play in pain modulation. This book contains chapters contributed by all of the major laboratories focused on understanding how cytokines modulate pain. These chapters provide a unique vantage point from which to examine this question, as the summarized work ranges from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans.

The Complex Reality of Pain

Author : Jennifer Corns
Publisher : Routledge
ISBN 13 : 1000027902
Total Pages : 216 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis The Complex Reality of Pain by : Jennifer Corns

Download or read book The Complex Reality of Pain written by Jennifer Corns and published by Routledge. This book was released on 2020-01-16 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book employs contemporary philosophy, scientific research, and clinical reports to argue that pain, though real, is not an appropriate object of scientific generalisations or an appropriate target for medical intervention. Each pain experience is instead complex and idiosyncratic in a way which undermines scientific utility. In addition to contributing novel arguments and developing a novel position on the nature of pain, the book provides an interdisciplinary overview of dominant models of pain. The author lays the needed groundwork for improved models and targeted treatments at a time when pain science, pain medicine, and philosophy are explicitly searching for both and failing to find them. The Complex Reality of Pain will be of interest to a broad range of researchers and students, including those working in philosophy of mind, philosophy of science, cognitive science, neuroscience, medicine, health, cognitive and behavioural psychology, and pain science.

Explain Pain

Author : David S Butler
Publisher : Noigroup Publications
ISBN 13 : 0987342673
Total Pages : 138 pages
Book Rating : 4.9/5 (873 download)

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Book Synopsis Explain Pain by : David S Butler

Download or read book Explain Pain written by David S Butler and published by Noigroup Publications. This book was released on 2013-07 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: Imagine an orchestra in your brain. It plays all kinds of harmonious melodies, then pain comes along and the different sections of the orchestra are reduced to a few pain tunes. All pain is real. And for many people it is a debilitating part of everyday life. It is now known that understanding more about why things hurt can actually help people to overcome their pain. Recent advances in fields such as neurophysiology, brain imaging, immunology, psychology and cellular biology have provided an explanatory platform from which to explore pain. In everyday language accompanied by quirky illustrations, Explain Pain discusses how pain responses are produced by the brain: how responses to injury from the autonomic motor and immune systems in your body contribute to pain, and why pain can persist after tissues have had plenty of time to heal. Explain Pain aims to give clinicians and people in pain the power to challenge pain and to consider new models for viewing what happens during pain. Once they have learnt about the processes involved they can follow a scientific route to recovery. The Authors: Dr Lorimer Moseley is Professor of Clinical Neurosciences and the Inaugural Chair in Physiotherapy at the University of South Australia, Adelaide, where he leads research groups at Body in Mind as well as with Neuroscience Research Australia in Sydney. Dr David Butler is an international freelance educator, author and director of the Neuro Orthopaedic Institute, based in Adelaide, Australia. Both authors continue to publish and present widely.

Genomics of Pain and Co-Morbid Symptoms

Author : Susan G. Dorsey
Publisher : Springer Nature
ISBN 13 : 3030216578
Total Pages : 254 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Genomics of Pain and Co-Morbid Symptoms by : Susan G. Dorsey

Download or read book Genomics of Pain and Co-Morbid Symptoms written by Susan G. Dorsey and published by Springer Nature. This book was released on 2020-06-15 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the field of pain genomics and the genomics of related, or co-occuring, symptoms, the current state-of-the-science, and challenges that remain. It brings differing views in the field together and provides examples of translational science from using cellular and rodent models to human clinical trials. This book's structure leads the reader through the physiology of pain and genomics into how pain is studied, mechanisms of acute and chronic pain, various protocols that are used throughout the field along with the pros/cons of the current methods used, and project into the future of pain genomics. This work is intended for classroom teaching, for nurses, for novice researchers in symptom science and pain research as well as students and postdoctoral fellows.

Understanding Pain for Better Clinical Practice

Author : Steven James Linton
Publisher : Elsevier Health Sciences
ISBN 13 : 0444515917
Total Pages : 192 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Understanding Pain for Better Clinical Practice by : Steven James Linton

Download or read book Understanding Pain for Better Clinical Practice written by Steven James Linton and published by Elsevier Health Sciences. This book was released on 2005-05-18 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive review of the current state of thinking and research in relation to the management of the psychological aspects of pain. Written in a style and at a level which is relevant and accessible to the practising clinician and also to students. Addresses the common clinical problems relating to the psychological aspects of pain management and gives practical guidance based on the latest research as to how those problems should be dealt with. Includes an appendix which may be used as a session manual by therapists using cognitive-behavioural therapy with groups for early intervention in pain management. May be used as a textbook as well as a clinical reference. Volume 16 in an established series conceived and commissioned by Sir Patrick Wall Written by probably the best known figure in the field of the psychological management of pain Clinically relevant and research based Written by a leading researcher who is also a practitioner and understands the problems and concerns of clinicians Fully up to the minute - based on the very latest research

An Introduction to Pain and its relation to Nervous System Disorders

Author : Anna A. Battaglia
Publisher : John Wiley & Sons
ISBN 13 : 1118455975
Total Pages : 453 pages
Book Rating : 4.1/5 (184 download)

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Book Synopsis An Introduction to Pain and its relation to Nervous System Disorders by : Anna A. Battaglia

Download or read book An Introduction to Pain and its relation to Nervous System Disorders written by Anna A. Battaglia and published by John Wiley & Sons. This book was released on 2016-05-02 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Pain and its relation to Nervous System Disorders provides an accessible overview of the latest developments in the science underpinning pain research, including, but not limited to, the physiological, pathological and psychological aspects. This unique book fills a gap in current literature by focussing on the intricate relationship between pain and human nervous system disorders such as Autism, Alzheimer Disease, Parkinson’s Disease, Depression and Multiple Sclerosis. This fully illustrated, colour handbook will help non-experts, including advanced undergraduate and new postgraduate students, become familiar with the current, wide-ranging areas of research that cover every aspect of the field from chronic and inflammatory pain to neuropathic pain and biopsychosocial models of pain, functional imaging and genetics. Contributions from leading experts in neuroscience and psychiatry provide both factual information and critical points of view on their approach and the theoretical framework behind their choices. An appreciation of the strengths and weaknesses of brain imaging technology applied to pain research in humans provides the tools required to understand current cutting edge literature on the topic. Chapters covering placebo effects in analgesia and the psychology of pain give a thorough overview of cognitive, psychological and social influences on pain perception. Sections exploring pain in the lifecycle and in relation to nervous system disorders take particular relevance from a clinical point of view. Furthermore, an intellectually stimulating chapter analysing the co-morbidity of pain and depression provides a philosophical angle rarely presented in related handbooks. The references to external research databases and relevant websites aim to prompt readers to become critical and independent thinkers, and motivate them to carry out further reading on these topics. Introduction to Pain and its relation to Nervous System Disorders is essential reading for advanced undergraduate and postgraduate students in neuroscience, medical and biomedical sciences, as well as for clinical and medical healthcare professionals involved in pain management.