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Oxygen And The Brain
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Book Synopsis Oxygen and the Brain: The Journey of Our Lifetime by : Philip B. James
Download or read book Oxygen and the Brain: The Journey of Our Lifetime written by Philip B. James and published by Best Publishing. This book was released on 2014-06-01 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Man has conquered Everest, been to the bottom of the deepest ocean, and even walked on the Moon by understanding pressure and oxygen. But the one area of life the technology has not influenced is the practice of medicine. Billions have been spent researching drugs to treat the brain and they have failed; drug companies are closing their neuroscience laboratories. This is because there is no substitute for oxygen. As the most astonishing discovery since DNA was unraveled has shown, oxygen, the gas in the air we all breathe, controls our most important genes. If we are sick or seriously injured and in intensive care, the amount of oxygen we can be given is limited by the weather. Without a simple pressure chamber, we are forced to accept a variation of more than 10% when just 2% more oxygen on the summit of Everest can mean the difference between life and death. We have already engineered the solution; the technology used in aircraft that sustains us flying at 40,000 feet can facilitate medical recovery safely on the ground. This book follows the human journey from conception to old age and presents evidence amassed over more than a century that can transform the care of patients with birth injury, head trauma, multiple sclerosis, stroke, and even reverse decline in old age. There is no more necessary and scientific action than to correct a deficiency of oxygen, especially in the brain and it is simple to give more.
Book Synopsis The Cerebral Circulation by : Marilyn J. Cipolla
Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Book Synopsis The Brain Without Oxygen by : Peter L. Lutz
Download or read book The Brain Without Oxygen written by Peter L. Lutz and published by R G Landes Company. This book was released on 1997-01-01 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Regulation of Tissue Oxygenation, Second Edition by : Roland N. Pittman
Download or read book Regulation of Tissue Oxygenation, Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Book Synopsis The Brain Without Oxygen by : P. L. Lutz
Download or read book The Brain Without Oxygen written by P. L. Lutz and published by . This book was released on 2014-01-15 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Oxygen Transport to Tissue XX by : Antal G. Hudetz
Download or read book Oxygen Transport to Tissue XX written by Antal G. Hudetz and published by Springer. This book was released on 2012-11-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: ''In addition to a wide variety of traditional oxygen transport topics, particular areas have been selected for emphasis at the 1997 meeting, which are: Molecular and genetic techniques to study oxygen transport in health and disease Angiogenesis during hypoxia, ischemia, and development Physiological mechanisms of oxygen sensing Physiological fluctuations of cerebral blood flow, metabolism and oxygenation Near infrared and phsophorescence techniques for the assessment of blood and tissue oxygenation Advances in biotechnology of anticoagulants and blood substitutes. '' (excerpted from the Preface).
Book Synopsis Annual Update in Intensive Care and Emergency Medicine 2012 by : Jean-Louis Vincent
Download or read book Annual Update in Intensive Care and Emergency Medicine 2012 written by Jean-Louis Vincent and published by Springer Science & Business Media. This book was released on 2012-09-23 with total page 844 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Yearbook compiles the most recent developments in experimental and clinical research and practice in one comprehensive reference book. The chapters are written by well recognized experts in the field of intensive care and emergency medicine. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.
Book Synopsis Oxygen and the Brain by : Philip B James
Download or read book Oxygen and the Brain written by Philip B James and published by . This book was released on 2017-04-11 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book follows the human journey from conception to old age and presents evidence amassed over more than a century that can transform the care of patients with birth injury, head trauma, multiple sclerosis, stroke, and even reverse decline in old age.
Book Synopsis The Brain Without Oxygen by : P.L. Lutz
Download or read book The Brain Without Oxygen written by P.L. Lutz and published by Springer Science & Business Media. This book was released on 2007-05-08 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is well known and researched, that deprivation of oxygen to the brain can quickly result in irreversible damage and death. What is less well known, is that some vertebrate species are exceptionally tolerant of brain hypoxia. The Brain Without Oxygen: Causes of failure - Physiological and molecular mechanisms for survival, Third edition, discusses the mechanisms of brain hypoxia tolerance in these exceptional vertebrates, which include diving marine mammals, high altitude dwellers and the hibernating mammal. Special attention is given to the extraordinary adaptations that allow a few turtle and fish species to tolerate months of brain anoxia. This third, fully updated edition addresses the potential of these animal models as targets for human clinical intervention. Perhaps the most interesting of these, are those involved in the suppression of metabolic activities to new set points well below their normoxic minima or maintenance levels. This volume will be valuable reading for researchers in physiology, medicine and general biological sciences, and of great importance to pharmaceutical companies researching novel models for stroke and brain ischemia.
Download or read book Oxygen Sensing written by and published by Elsevier. This book was released on 2004-05-10 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.
Author :Marian S. McDonagh Publisher :Department of Health and Human Services Public Health Servic ISBN 13 :9781587631382 Total Pages :0 pages Book Rating :4.6/5 (313 download)
Book Synopsis Hyperbaric Oxygen Therapy for Brain Injury, Cerebral Palsy, and Stroke by : Marian S. McDonagh
Download or read book Hyperbaric Oxygen Therapy for Brain Injury, Cerebral Palsy, and Stroke written by Marian S. McDonagh and published by Department of Health and Human Services Public Health Servic. This book was released on 2003 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Oxygen Revolution, Third Edition by : Paul G. Harch, M.D.
Download or read book The Oxygen Revolution, Third Edition written by Paul G. Harch, M.D. and published by Hatherleigh Press. This book was released on 2016-06-21 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: NEW 2016 EDITION INCLUDES NEW RESEARCH ON HBOT AS A GENE THERAPY TO TREAT TRAUMATIC BRAIN INJURY (TBI) AND OTHER DISORDERS. Hyperbaric oxygen therapy (HBOT) is based on a simple idea—that oxygen can be used therapeutically for a wide range of conditions where tissues have been damaged by oxygen deprivation. Inspiring and informative, The Oxygen Revolution, Third Edition is the comprehensive, definitive guide to the miracle of hyperbaric oxygen therapy. HBOT directly affects the body at the genetic level, affecting over 8,000 individual genes—those responsible for healing, growth, and anti-inflammation. Dr. Paul G. Harch’s research and clinical practice has shown that this noninvasive and painless treatment can help those suffering from brain injury or such diseases as: - Stroke - Autism and other learning disabilities - Cerebral palsy and other birth injuries - Alzheimer’s, Parkinson’s, multiple sclerosis, and other degenerative neurological diseases - Emergency situations requiring resuscitation, such as cardiac arrest, carbon monoxide poisoning, or near drowning For those affected by these seemingly “hopeless” diseases, there is finally hope in a proven solution: HBOT. From the Trade Paperback edition.
Book Synopsis Monitoring of Cerebral Blood Flow and Metabolism in Intensive Care by : Andreas Unterberg
Download or read book Monitoring of Cerebral Blood Flow and Metabolism in Intensive Care written by Andreas Unterberg and published by Springer. This book was released on 2012-02-28 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until recently, monitoring of cerebral blood flow and metabolism was an unattained goal. Determination of cerebral blood flow was limited to intermittent measurements and particularly difficult to perform in critically ill patients. Meanwhile there are techniques available, however, to monitor cerebral blood flow and cerebral oxygenation, both globally and regionally. Therefore we thought it worthwhile to discuss these new continuous techniques and to compare them with well-known techniques which discontinuously measure CBF. For that purpose, an international workshop with some leading experts in the field was held in October 1992 in Berlin. The workshop consisted of about 20 lectures, either reviews on a special topic, or latest results. These contributions were given by invitation and were extensively discussed. Unfortunately it is impossible to reproduce the discussions. On the other hand, all speakers delivered a manuscript promptly after the meeting so that we were able to edit them within a short time. Since monitoring of cerebral blood flow in intensive care is a rapidly growing and changing topic, the written contributions should be quickly available. Authors, editors and publishers have tried to come close to this ideal. As editors we would like to thank the authors and the publishers who enabled us to come out with this volume of the proceedings as early as possible.
Book Synopsis Magnetic Resonance Spectroscopy by : Charlotte Stagg
Download or read book Magnetic Resonance Spectroscopy written by Charlotte Stagg and published by Academic Press. This book was released on 2013-11-11 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Spectroscopy: Tools for Neuroscience Research and Emerging Clinical Applications is the first comprehensive book for non-physicists that addresses the emerging and exciting technique of magnetic resonance spectroscopy. Divided into three sections, this book provides coverage of the key areas of concern for researchers. The first, on how MRS is acquired, provides a comprehensive overview of the techniques, analysis, and pitfalls encountered in MRS; the second, on what can be seen by MRS, provides essential background physiology and biochemistry on the major metabolites studied; the final sections, on why MRS is used, constitutes a detailed guide to the major clinical and scientific uses of MRS, the current state of teh art, and recent innovations. Magnetic Resonance Spectroscopy will become the essential guide for people new to the technique and give those more familiar with MRS a new perspective. Chapters written by world-leading experts in the field Fully illustrated Covers both proton and non-proton MRS Includes the background to novel MRS imaging approaches
Book Synopsis Oxygen Transport to Tissue XLI by : Pan-Dong Ryu
Download or read book Oxygen Transport to Tissue XLI written by Pan-Dong Ryu and published by Springer Nature. This book was released on 2019-12-31 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents cutting-edge papers and perspectives on the transport of oxygen to tissues by scientists in a multitude of disciplines such as biochemistry, engineering, mathematics, medicine, physics, physiology, veterinary and complementary medicine. The book is composed of the following 6 parts: Brain Oxygenation and Function, Tumor Oxygenation and Metabolism, Muscle Oxygenation and Sports Medicine, Cell Metabolism and Tissue Oxygenation, Methodology of O2 Measurements, and Special Topics. The articles in this book have been presented at the 46th annual meeting of the International Society on Oxygen Transport to Tissue (ISOTT 2018) held in Seoul, Republic of Korea, from July 1 to July 5, 2018. Academics, clinical and industry researchers, engineers, as well as graduate students who are interested in oxygen transport to tissue will find this book a great reference and a useful learning resource.
Book Synopsis The Brain Without Oxygen by : Peter L. Lutz
Download or read book The Brain Without Oxygen written by Peter L. Lutz and published by . This book was released on 1994 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Management of Severe Traumatic Brain Injury by : Terje Sundstrøm
Download or read book Management of Severe Traumatic Brain Injury written by Terje Sundstrøm and published by Springer Science & Business Media. This book was released on 2012-06-25 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: In order to reduce the number of deaths from severe head injuries, systematic management is essential. This book is a practical, comprehensive guide to the treatment of patients (both adults and children) with such injuries, from the time of initial contact through to the rehabilitation center. Sections are devoted to prehospital treatment, admission and diagnostics, acute management, and neurointensive care and rehabilitation. Evidence-based recommendations are presented for each diagnostic and therapeutic measure, and tips, tricks, and pitfalls are highlighted. Throughout, the emphasis is on the provision of sound clinical advice that will maximize the likelihood of an optimal outcome. Helpful flowcharts designed for use in daily routine are also provided. The authors are all members of the Scandinavian Neurotrauma Committee and have extensive practical experience in the areas they write about.
