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Oxidative Stress In Male Infertility
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Book Synopsis Male Infertility: Understanding, Causes and Treatment by : RAJENDER SINGH
Download or read book Male Infertility: Understanding, Causes and Treatment written by RAJENDER SINGH and published by Springer. This book was released on 2017-06-17 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest research on male infertility. The topics discussed range from understanding the genetic basis of infertility, to its causes and treatment. Since infertility is also of great interest to the general public, the book also includes a detailed description of what infertility is and how one can understand the different types. Given the complex etiology of infertility, the book includes a number of chapters defining the known and probable causes of male infertility. Providing detailed information suitable for patients and clinicians alike, it also features a separate section on treatment, the ultimate goal.
Book Synopsis Oxidants, Antioxidants, and Impact of the Oxidative Status in Male Reproduction by : Ralf Henkel
Download or read book Oxidants, Antioxidants, and Impact of the Oxidative Status in Male Reproduction written by Ralf Henkel and published by Academic Press. This book was released on 2018-08-23 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidants, Antioxidants and Impact of the Oxidative Status in Male Reproduction is an essential reference for fertility practitioners and research and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology. The book focuses on unravelling the pathophysiology of oxidative stress mediated male infertility, recruiting top researchers and clinicians to contribute chapters. This collection of expertise delves into the physico-chemical aspects of oxidative stress, including a new focus on reductive stress. Furthermore, the inclusion of clinical techniques to determine oxidative stress and the OMICS of reductive oxidative stress are also included. This is a must-have reference in the area of oxidative stress and male reproductive function. - Offers comprehensive information on oxidative stress and its role in male reproduction, including new therapeutic approaches - Deals with current approaches to oxidative stress using OMICS platform - Designed for fertility practitioners, reproductive researchers, and laboratory professionals interested in learning about the role of reactive oxygen species in sperm physiology and pathology
Book Synopsis Varicocele and Male Infertility by : Alaa Hamada
Download or read book Varicocele and Male Infertility written by Alaa Hamada and published by Springer. This book was released on 2015-12-07 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This SpringerBrief analyzes varicocele from a novel approach, and provides the reader with a comprehensive view of its scientific and clinical significance. The Brief covers all the important aspects of varicocele related to infertility, from epidemiology to assisted reproduction techniques, contemplating pathophysiology, semen analysis, specialized sperm function tests, and clinical management including all available treatment options form three distinct perspectives, i.e., current concepts, consensus and controversies. Each topic is addressed using the same template, offering the best information from all angles to readers. This SpringerBrief is aimed at both clinicians and scientists involved in the study and care of male and female fertility, and is written by a team of three internationally recognized authors with expertise in andrology and male infertility. The text is the first of its kind, and presents an invaluable tool both for the basic scientists with an interest in reproductive medicine and for clinicians working in the field of infertility.
Book Synopsis Antioxidants in Male Infertility by : Sijo J. Parekattil
Download or read book Antioxidants in Male Infertility written by Sijo J. Parekattil and published by Springer. This book was released on 2013-11-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise, truncated version of Parekattil and Agarwal's Male Infertility: Contemporary Clinical Approaches, Andrology, ART & Antioxidants is the first resource dedicated solely to antioxidants and male infertility. With select chapters that will prove invaluable to the practitioner of reproductive medicine, Antioxidants in Male Infertility addresses issues such as: - Molecular mechanisms of antioxidants in male infertility - Oxidative stress - The impact of infection, aging, obesity, and injury on male infertility - Natural and synthetic antioxidants and antioxidant therapy - Antioxidants in ICSI and IMSI Also included is a new chapter reviewing the physiological role of reactive oxygen species in sperm function. Practical for clinicians and researchers alike, Antioxidants in Male Infertility contains all of the need-to-know information about these cutting-edge topics in reproductive medicine.
Book Synopsis Male Infertility by : Karthik Gunasekaran
Download or read book Male Infertility written by Karthik Gunasekaran and published by Springer. This book was released on 2016-11-09 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book aims to bring into focus the current understanding of male reproduction and the pathological basis of failure to reproduce in men. Infertility in men is a common disorder. However, attempts at scientific study of male infertility are of very recent origin. Many questions about the physiology and pathophysiology of male reproduction are still not clear. The chapters are written by authorities in the field with great clinical experience. The primary focus would be on clinical perspective; however emphasis would also be placed on basic research and molecular biology.
Book Synopsis Andrological Evaluation of Male Infertility by : Ashok Agarwal
Download or read book Andrological Evaluation of Male Infertility written by Ashok Agarwal and published by Springer. This book was released on 2016-07-26 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of-the-art laboratory manual includes 20 clinical protocols used daily for the investigation of the infertile male, presented with easy to understand, step-by-step methodology. The protocols are arranged from routine to advanced laboratory procedures common to clinical practice, including computer-assisted semen analysis, sperm preparation for IUI by density gradient and swim-up, sperm cryopreservation, and sperm DNA fragmentation test by TUNEL method, among others. The methodology in each protocol follows best practice guidelines made clearer by professionally hand-drawn illustrations covering most of the important steps and equipment. The authors, hailing from the world-renowned Andrology Center at Cleveland Clinic, have over 50 years of combined first-hand experience in managing very busy diagnostic and research facilities in male infertility and andrology. The book will be an indispensable resource for thousands of laboratory technologists, clinicians and reproductive professionals (andrologists, embryologist, etc.) engaged in the diagnosis and management of infertile men around the world.
Book Synopsis New Discoveries in Embryology by : Bin Wu
Download or read book New Discoveries in Embryology written by Bin Wu and published by BoD – Books on Demand. This book was released on 2015-10-21 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal individual life begins as combination of sperm and oocyte, which results in the embryogenesis from ovum fertilization to fetal stage. Embryology has become one central discipline for many modern biotechnologies. Although this subject has been studied for more than a century, new discoveries appear continuously. This book contains some new discoveries and updates some theories and technologies in animal and human embryology. Major content include new findings in gamete biology, new theories and discoveries in embryo implantation by three-dimensional imaging technology and new concept and actual application of embryology. Thus, this book will greatly update knowledge in embryology field and provide some basic theories and technologies for animal scientists and breeders as well as embryologists and anthropologists.
Book Synopsis Varicocele and Male Infertility by : Sandro C Esteves
Download or read book Varicocele and Male Infertility written by Sandro C Esteves and published by Springer Nature. This book was released on 2019-09-11 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique textbook – the first of its kind – presents a thoughtful and comprehensive discussion of the significance of varicocele and its impact on male fertility. This hot topic is covered from a multitude of angles in seven thematic sections: origin and pathophysiology, clinical evaluation, medical and surgical therapy, controversies, pro and con debates, and clinical case scenarios. The scope of varicocele includes basic and transitional research, genetics, diagnostic testing with conventional and advanced molecular biology approaches, hormonal control, interventional therapy and assisted reproductive technology (ART). Repair of varicocele, which can be carried out by various methods, not only alleviates oxidative stress‐associated infertility but also prevents and protects against the progressive character of varicocele and its consequent upregulations of systemic oxidative stress. Even with the advances in the understanding of this intriguing disease and consensus on some areas such as diagnosis and pathophysiology, substantial controversy still exists, in particular concerning the benefits of treatment and to whom treatment should be offered. Additional chapters discuss, in depth, such controversies surrounding the role of varicocele in male infertility and present clinical case scenarios dealing with management of subclinical and clinical varicocele. A series of editorial comments is provided by the editors at the end of selected chapters, containing an objective and concise summary of the information from each chapter. In addition, chapters open up with key points for quick references and conclude with multiple choice questions and answers for immediate review and retention of the rich content. Generously illustrated, Varicocele and Male Infertility: A Complete Guide represents an invaluable tool for medical students in reproductive medicine as well as researchers and clinicians working in the field of infertility (e.g., urologists, gynecologists, reproductive endocrinologists, and embryologists) and is comprised of chapters written by leading and internationally recognized clinicians and scientists with expertise in varicocele, skillfully edited by leaders in the field.
Book Synopsis Manual of Sperm Function Testing in Human Assisted Reproduction by : Ashok Agarwal
Download or read book Manual of Sperm Function Testing in Human Assisted Reproduction written by Ashok Agarwal and published by Cambridge University Press. This book was released on 2021-04-15 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on modern sperm function testing, this guide is essential in selecting sperm that will produce viable and healthy embryos.
Book Synopsis Infertility in the Male by : Larry I. Lipshultz
Download or read book Infertility in the Male written by Larry I. Lipshultz and published by Cambridge University Press. This book was released on 2009-09-24 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.
Book Synopsis Clinical Management of Male Infertility by : Giorgio Cavallini
Download or read book Clinical Management of Male Infertility written by Giorgio Cavallini and published by Springer. This book was released on 2014-10-20 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasing importance. Clinicians will find that the book’s straightforward approach ensures that it can be easily and rapidly consulted.
Book Synopsis Reactive Oxygen Species (ROS) in Living Cells by : Filip Cristiana
Download or read book Reactive Oxygen Species (ROS) in Living Cells written by Filip Cristiana and published by BoD – Books on Demand. This book was released on 2018-05-23 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxygen represents only 20% of the Earth's atmosphere, yet it is vital for the survival of aerobic organisms. There is a dark part of the use of oxygen that consists in generating reactive species that are potentially harmful to living organisms. Moreover, reactive oxygen species can combine with nitrogen derivatives and generate many other reactive species. Thus, living organisms are continuously assaulted by reactive species from external or internal sources. However, the real danger comes in the case of high concentrations and prolonged exposure to these species. This book presents an image of the mechanisms of action of reactive species and emphasizes their involvement in diseases. Inflammation and cancer are examined to determine when and how reactive species turn the evolution of a benign process to a malignant one. Some answers may come from recent studies indicating that reactive species are responsible for epigenetic changes.
Book Synopsis A Clinician's Guide to Sperm DNA and Chromatin Damage by : Armand Zini
Download or read book A Clinician's Guide to Sperm DNA and Chromatin Damage written by Armand Zini and published by Springer. This book was released on 2018-03-05 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natural and ART-assisted pregnancies, and debates the clinical utility of such tests. Finally, part V discusses current treatment options, such as antioxidant therapy, varicocelectomy, advanced sperm processing techniques and the use of testicular sperm. We are now beginning to better understand the unique organization of the sperm chromatin, as well as the nature and etiology of sperm DNA damage. Written and edited by worldwide experts in andrology, A Clinician's Guide to Sperm DNA and Chromatin Damage is an excellent resource for reproductive medicine and REI specialists, urologists, reproductive biologists and any professional working with the infertile male.
Book Synopsis Studies on Men's Health and Fertility by : Ashok Agarwal
Download or read book Studies on Men's Health and Fertility written by Ashok Agarwal and published by Springer Science & Business Media. This book was released on 2012-03-17 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies on Men’s Health and Fertility provides a comprehensive series of up-to-the-minute reviews addressing the role of oxidative stress in the aetiology of reproductive pathologies in the male. This volume represents by far the most detailed, authoritative review of the field that has been produced to date. The text encompasses the basic science of reactive oxygen species (ROS) production by mammalian spermatozoa, the way in which these highly reactive molecules are processed by the germ line and the physiological significance of this redox activity in the generation of a functional gamete. The factors responsible for perturbing the delicate balance between physiological redox signaling on the one hand and oxidative stress on the other are also extensively reviewed and some of the first clues concerning the underlying mechanisms (age, heat, infection, cryostorage, aberrant lipid metabolism), clearly identified. From a clinical perspective there are chapters setting out the methods we should be using to diagnose oxidative stress in the male germ line, a clinical perspective on the aetiology of this condition and detailed considerations of the most suitable means of ameliorating such stress from a therapeutic point of view. Studies on Men’s Health and Fertility is intended to provide clinicians and scientists with a snap shot of the current status of this exciting, rapidly moving field. The book will be of value to clinicians interested in strategies for the management of oxidative stress in their infertility patients and scientists wishing to understand the molecular mechanisms underpinning the generation of ROS by these cells and its pathophysiological significance. It was not so long ago that the ability of spermatozoa to generate ROS was a hotly disputed topic. With the publication of this book such doubts can finally be laid to rest. There is now no doubt that these cells actively generate ROS, that oxidative stress is a major contributor to defects in male reproductive health and that the successful clinical management of this condition depends on developing a deeper understanding of the underlying molecular mechanisms. In this quest, Studies on Men’s Health and Fertility will be seen as a clear and important milestone.
Book Synopsis Assisted Reproduction Techniques by : Khaldoun Sharif
Download or read book Assisted Reproduction Techniques written by Khaldoun Sharif and published by John Wiley & Sons. This book was released on 2012-03-26 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assisted reproduction techniques have led to the birth of 4 million babies worldwide Assisted reproduction techniques (ART), in particular in-vitro fertilization and intra-cytoplasmic sperm injection, are the most advanced forms of infertility treatment. They involve numerous counseling, medical, surgical and laboratory-based steps. At each step various problems and complications could be encountered that challenge even the most experienced ART practitioners. Moreover, patients with complex medical disorders may require ART, presenting further challenges. Assisted Reproduction Techniques will stimulate resourceful thinking in the ART practitioner when faced with these challenges. It outlines various management options, the reasoning behind them, and the evidence on which they are based to enable the practitioner to choose the most suitable solution for the needs of each patient. Written by 122 internationally renowned experts, Assisted Reproduction Techniques follows the patient's journey throughout the whole ART process, with chapters on: Counseling and preparation Ovarian stimulation Oocyte retrieval Embryo transfer The luteal phase The ART laboratory The male patient The ART pregnancy Each of the 100 concise chapters includes clinical cases, background, evidence-based practical management options, preventive measures and key-point summaries of the important details. Assisted Reproduction Techniques gives a wide-ranging practical guide to all those wishing to support couples who cannot conceive naturally.
Download or read book Sperm Chromatin written by Armand Zini and published by Springer Science & Business Media. This book was released on 2011-08-04 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage. The work covers the fundamental principles of sperm chromatin architecture and function, the proposed modes of DNA damage and repair, the tests of sperm DNA damage, the clinical aspects of DNA damage and the impact of DNA damage on reproductive outcome. Unlike any other title on the topic, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction is an invaluable addition to the literature and will serve as an indispensable resource for basic scientists with an interest in sperm biology and for urologists, gynecologists, reproductive endocrinologists, and embryologists working in the field of infertility.
Book Synopsis Exercise and Human Reproduction by : Diana Vaamonde
Download or read book Exercise and Human Reproduction written by Diana Vaamonde and published by Springer. This book was released on 2016-03-07 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive review of the interactions between exercise and human reproduction, this unique text focuses on both the positive and negative consequences of sport and physical activity on male and female fertility and infertility and the biological mechanisms and processes behind them. Beginning with a review of the structure and function of the male and female reproductive systems as well as fertilization and gestation, the discussion then turns to the physiology and endocrinology of sport and exercise, which is further elaborated in subsequent chapters on the impact of physical activity, hormonal changes, pathologies, and consequences of drug use for active men and women. Additional chapters address related topics, such as the impact of sport on young athletes and developing reproductive potential, physical activity and pregnancy, the use of oral contraceptives in athletes, oxidative stress, and the impact of nutritional deficiencies on athletes’ fertility, with a final chapter providing recommendations and therapeutic guidelines for exercise-related reproductive disorders. Covering everything from the fundamental principles of sports physiology and human reproductive potential to the interaction between physical exercise and the endocrinology of the reproductive system, Exercise and Human Reproduction is an authoritative resource for helping clinicians understand how the reproductive system adapts to activity and exercise and offers strategies to avoid potential harm to human reproduction.
