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Osteoimmunology
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Download or read book Osteoimmunology written by Joseph Lorenzo and published by Academic Press. This book was released on 2015-09-23 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis. Explains the intricate interaction between the immune system and bone Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems
Download or read book Osteoimmunology written by Yongwon Choi and published by Springer Science & Business Media. This book was released on 2007-10-05 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with estrogen receptors as treatment of arthritis and osteoporosis.- Novel Signaling Pathways And Therapeutic Targets In Osteoclasts.- The Enigmatic Function of TREM-2 in Osteoclastogenesis.- Role of cell-matrix interactions in osteoclast differentiation.- Positive and negative roles of IL-6, STAT3 and SOCS3 in inflammatory arthritis.- Control of Osteoclast activity and bone loss by IKK subunits: new targets for therapy.- Targeting Osteoporosis And Rheumatoid Arthritis By Active Vaccination Against Rankl.- RANKL Inhibition: From Mice to Men (and Women).
Book Synopsis Principles of Osteoimmunology by : Peter Pietschmann
Download or read book Principles of Osteoimmunology written by Peter Pietschmann and published by Springer. This book was released on 2016-08-18 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated and extended second edition provides a comprehensive overview on the basic concepts of the rapidly developing field of osteoimmunology and also offers in-depth insights into the molecular mechanisms of bone diseases. Clinical data is presented and put into context with the latest research findings. This second edition in addition discusses the latest topics in transplantation immunology. The book addresses scientists and physicians working in immunology, pathophysiology and osteology.
Book Synopsis Updates on Osteoimmunology: What’s New on the Crosstalk Between Bone and Immune Cells by : Giacomina Brunetti
Download or read book Updates on Osteoimmunology: What’s New on the Crosstalk Between Bone and Immune Cells written by Giacomina Brunetti and published by Frontiers Media SA. This book was released on 2020-03-24 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Osteoimmunology written by Yongwon Choi and published by Springer Science & Business Media. This book was released on 2007-10-01 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with estrogen receptors as treatment of arthritis and osteoporosis.- Novel Signaling Pathways And Therapeutic Targets In Osteoclasts.- The Enigmatic Function of TREM-2 in Osteoclastogenesis.- Role of cell-matrix interactions in osteoclast differentiation.- Positive and negative roles of IL-6, STAT3 and SOCS3 in inflammatory arthritis.- Control of Osteoclast activity and bone loss by IKK subunits: new targets for therapy.- Targeting Osteoporosis And Rheumatoid Arthritis By Active Vaccination Against Rankl.- RANKL Inhibition: From Mice to Men (and Women).
Download or read book Osteoimmunology written by Yongwon Choi and published by Springer Science & Business Media. This book was released on 2009-12-01 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. The conference will bring together leading international scientists from both fields to interact so that new collaboration can develop and more rapid progress in understanding the relationships between these fields can be achieved. Short talks will be selected from abstracts from the international community. This conference will have a format to provide an environment of maximum interaction and interchange through lectures, posters, and open discussion.
Book Synopsis Advances in Osteoimmunology by : Claudine Blin-Wakkach
Download or read book Advances in Osteoimmunology written by Claudine Blin-Wakkach and published by Frontiers Media SA. This book was released on 2020-01-21 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Recent Advances in Basic and Translational Osteoimmunology by : Rupesh K. Srivastava
Download or read book Recent Advances in Basic and Translational Osteoimmunology written by Rupesh K. Srivastava and published by Frontiers Media SA. This book was released on 2022-01-10 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Innate Immunity in the Context of Osteoimmunology, 2nd Edition by : Cristina Sobacchi
Download or read book Innate Immunity in the Context of Osteoimmunology, 2nd Edition written by Cristina Sobacchi and published by Frontiers Media SA. This book was released on 2021-07-01 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS. Part of the APCs for articles in this collection were financed by the Fondazione Beppe e Nuccy Angiolini ONLUS. Publisher’s note: In this 2nd edition, acknowledgment for the Fondazione Beppe e Nuccy Angiolini ONLUS has been added.
Book Synopsis Bone metastasis in the milieu of Osteoimmunology by : Jawed A. Siddiqui
Download or read book Bone metastasis in the milieu of Osteoimmunology written by Jawed A. Siddiqui and published by Frontiers Media SA. This book was released on 2023-09-01 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone metastases are common in many cancers and associated with skeletal-related events such as spinal cord compression, fractures, pain, disability, and impaired quality of life. Bone metastasis is most prominent in breast, prostate, and lung cancer patients and is the leading cause of cancer-associated death. Osteoblasts and osteoclasts control each other’s functions to maintain normal bone homeostasis. In addition, bone remodeling is governed by the balanced activity of the bone and immune cells. Bone metastasis is a multistage process, and the bone microenvironment influences the seeding and colonization of the disseminated cancer cells. Disruption of bone homeostasis and immune population provides fertile soil to facilitate cancer cell seeding. Despite the advancement of our understanding to treat primary tumors, most of the treatments for bone metastasis are palliative. Proper understanding of the immune component of the bone and their involvement in bone metastasis niche formation will help to explore future directions of bone metastasis research.
Book Synopsis Updates on Osteoimmunology: What's New on the Crosstalk Between Bone and Immune Cells by : Giacomina Brunetti
Download or read book Updates on Osteoimmunology: What's New on the Crosstalk Between Bone and Immune Cells written by Giacomina Brunetti and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last twenty years, different discoveries have emphasized the cross-talk between bone and immune cells as well as their common regulatory pathways. Indeed, soluble molecules produced by immune cells modulate the behavior of osteoblasts and osteoclasts. Moreover, osteoclasts, the bone-resorbing cells, originate from the same myeloid precursor cells that differentiated into macrophages and myeloid dendritic cells. Whereas, the bone-forming osteoblastic cells control hematopoietic stem cell niches and thus immune cell ontology. The amplified recognition of the complex relationship between the immune system and bone led to the designation of osteoimmunology field. This Research Topic collects articles that highlight the cross-talk between bone and immune cells,
Book Synopsis Osteoimmunology : interactions of the immune and skeletal systems by : Joseph Lorenzo
Download or read book Osteoimmunology : interactions of the immune and skeletal systems written by Joseph Lorenzo and published by . This book was released on 2011 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Osteogenesis and Bone Regeneration by : Haisheng Yang
Download or read book Osteogenesis and Bone Regeneration written by Haisheng Yang and published by BoD – Books on Demand. This book was released on 2019-04-24 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteogenesis is a core component of the skeletal system and depends on the well-coordinated proliferation and differentiation of osteogenic cells. Multiple signaling pathways and transcriptional factors tightly regulate the process of osteogenesis. Any abnormities in bone formation could cause severe disorders such as osteogenesis imperfecta and osteoporosis. Bone regeneration, a complex and well-orchestrated physiological process of osteogenesis, remains a medical challenge in the field of orthopedics and maxillofacial surgery. This book provides an overview of the current developments in osteogenesis and bone regeneration, including molecular and cellular mechanisms, physical therapies (low-level laser, distraction osteogenesis), biological therapies (mesenchymal stem cells, stem cell derived exosomes, inflammatory factor, Chinese medicine), as well as tissue engineering approaches promoting bone regeneration by targeting osteogenesis.
Book Synopsis The Immune Response to Implanted Materials and Devices by : Bruna Corradetti
Download or read book The Immune Response to Implanted Materials and Devices written by Bruna Corradetti and published by Springer. This book was released on 2016-11-30 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.
Book Synopsis Recent Progress in Osteoimmunology by : Melonie Armstrong
Download or read book Recent Progress in Osteoimmunology written by Melonie Armstrong and published by American Medical Publishers. This book was released on 2023-09-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Osteoimmunology is the study of the correlation between bone and immune cells. It emphasizes the two sided communication that takes place among the immune cells and bones. The interactions taking place between the immune system and bone are critical in maintaining skeletal homeostasis. The bone marrow cavity is essential for the growth of the immune system. It also houses crucial stem cells for maintaining the immune system. Immune cells create cytokines, which have crucial effects on the modulation of bone homeostasis. There are a few critical cytokines, which are produced by the immune system, such as TNF-α, RANKL, IFNs, M-CSF and ILs. These affect the activity and differentiation of bone resorption and osteoclasts. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of osteoimmunology. It will prove to be immensely beneficial to students and researchers in this field.
Download or read book Osteoimmunology written by Joseph Lorenzo and published by . This book was released on 2005 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bone Regulators and Osteoporosis Therapy by : Paula H. Stern
Download or read book Bone Regulators and Osteoporosis Therapy written by Paula H. Stern and published by Springer. This book was released on 2020-11-29 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is designed to provide an understanding of current and potential therapies for osteoporosis. The opening chapter introduces the cells of bone and their interactions. Several following chapters describe factors affecting bone including systemic hormones with significant effects on bone, and local mediators including growth factors, prostaglandins, cytokines and chemokines. Topics that have commanded particular attention recently are calcium, FGF-23, nervous system bone interactions. Drugs that cause bone loss provide important information on mechanism as well as therapeutic considerations. An overview of the genetics of bone disorders and a discussion of the pathophysiology of osteoporosis establish the clinical context. The final chapters discuss current and potential osteoporosis treatments.
