Organogenetic Gene Networks

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Publisher : Springer
ISBN 13 : 3319427679
Total Pages : 375 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Organogenetic Gene Networks by : James Castelli-Gair Hombría

Download or read book Organogenetic Gene Networks written by James Castelli-Gair Hombría and published by Springer. This book was released on 2016-08-26 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: All animals, including humans, derive from a single cell, which possesses all the genetic instructions needed to define how the animal will look like. However, during development, the millions of cells that derive from the zygote will only select part of this genetic information to give rise to the various organs of the body. The coordination of different cell behaviours during development results in the formation of specialized tissues and organs giving rise to highly adapted animals. This book provides an overview of how this diversification is achieved during organ formation and how it may have evolved. Conserved cellular processes are presented using examples from selected vertebrate and invertebrate species that illustrate how developmental biologists are solving the complex puzzle of organ formation. This volume is aimed to students, researchers and medical doctors alike who want to find a simple but rigorous introduction on how gene networks control organ formation.“div> /div

Gene Regulatory Networks

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Publisher : Academic Press
ISBN 13 : 0128131810
Total Pages : 450 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Gene Regulatory Networks by :

Download or read book Gene Regulatory Networks written by and published by Academic Press. This book was released on 2020-05-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Regulatory Networks, Volume 139 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics in this release include Mouse hindbrain GRN, Xenopus endoderm GRN – organogenesis, Vertebrate limb GRN, The notochord gene regulatory network in chordate evolution: conservation and divergence from Ciona to vertebrates, Ciona early embryo GRNs, Boolean logic models, Modeling GRN response to morphogen gradient, GRN architecture, Theory of GRN evolution, Evolution of fly segmentation GRNs, GRN evolution in echinoderms, Evolution of network specificity, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Includes the latest information on gene regulatory networks

Network Function Shapes Network Structure: the Case of the Arabidopsis Flower Organ Specification Genetic Network

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (931 download)

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Book Synopsis Network Function Shapes Network Structure: the Case of the Arabidopsis Flower Organ Specification Genetic Network by :

Download or read book Network Function Shapes Network Structure: the Case of the Arabidopsis Flower Organ Specification Genetic Network written by and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The reconstruction of many biological networks has allowed detailed studies of their structural properties. Several features exhibited by these networks have been interpreted to be the result of evolutionary dynamics. For instance the degree distributions may follow from a preferential attachment of new genes to older ones during evolution. Here we argue that even in the absence of any evolutionary dynamics, the presence of atypical features may follow from the fact that the network implements certain functions. To examine this network function shapes network structure scenario, we focus on the Arabidopsis genetic network controlling early flower organogenesis in which gene expression dynamics has been modelled using a Boolean framework. Specifically, for a system with 15 master genes, the phenotype consists of 10 experimentally determined steady-state expression patterns, considered here as the functional constraints on the network. The space of genetic networks satisfying these constraints is sometimes referred to as the neutral or genotype network. We sample this space using Markov Chain Monte Carlo which allows us to exhibit how the functional (phenotypic) constraints shape the gene network structure. We find that this shaping is strongest for the edge (interaction) usage, with effects that are functionally interpretable. In contrast, higher order features such as degree assortativity and network motifs are hardly shaped by the phenotypic constraints.

A Multipartite Approach to Mapping the Gene Network Directing Caenorhabditis Elegans Vulval Organogenesis /cTed Olin Ririe ; Paul W. Sternberg, Committee Chair and Advisor

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Publisher :
ISBN 13 :
Total Pages : 258 pages
Book Rating : 4.:/5 (437 download)

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Book Synopsis A Multipartite Approach to Mapping the Gene Network Directing Caenorhabditis Elegans Vulval Organogenesis /cTed Olin Ririe ; Paul W. Sternberg, Committee Chair and Advisor by : Ted Olin Ririe

Download or read book A Multipartite Approach to Mapping the Gene Network Directing Caenorhabditis Elegans Vulval Organogenesis /cTed Olin Ririe ; Paul W. Sternberg, Committee Chair and Advisor written by Ted Olin Ririe and published by . This book was released on 2009 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Plant Systems Biology

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Publisher : Springer Science & Business Media
ISBN 13 : 376437439X
Total Pages : 362 pages
Book Rating : 4.7/5 (643 download)

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Book Synopsis Plant Systems Biology by : Sacha Baginsky

Download or read book Plant Systems Biology written by Sacha Baginsky and published by Springer Science & Business Media. This book was released on 2007-06-25 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume aims to provide a timely view of the state-of-the-art in systems biology. The editors take the opportunity to define systems biology as they and the contributing authors see it, and this will lay the groundwork for future studies. The volume is well-suited to both students and researchers interested in the methods of systems biology. Although the focus is on plant systems biology, the proposed material could be suitably applied to any organism.

Gene Networks in Development

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Publisher :
ISBN 13 :
Total Pages : 156 pages
Book Rating : 4.:/5 (134 download)

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Book Synopsis Gene Networks in Development by : Ernest Rowell Jackson

Download or read book Gene Networks in Development written by Ernest Rowell Jackson and published by . This book was released on 1985 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Systems Biology of Early Mouse Inner Ear Organogenesis

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Publisher :
ISBN 13 :
Total Pages : 634 pages
Book Rating : 4.:/5 (233 download)

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Book Synopsis A Systems Biology of Early Mouse Inner Ear Organogenesis by : Samin Ahmed Sajan

Download or read book A Systems Biology of Early Mouse Inner Ear Organogenesis written by Samin Ahmed Sajan and published by . This book was released on 2008 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Molecular Biology of The Cell

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Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)

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Book Synopsis Molecular Biology of The Cell by : Bruce Alberts

Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Plant Development and Organogenesis

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Publisher : MDPI
ISBN 13 : 3039281267
Total Pages : 246 pages
Book Rating : 4.0/5 (392 download)

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Book Synopsis Plant Development and Organogenesis by : Giovanna Frugis

Download or read book Plant Development and Organogenesis written by Giovanna Frugis and published by MDPI. This book was released on 2020-01-23 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: The way plants grow and develop organs significantly impacts the overall performance and yield of crop plants. The basic knowledge now available in plant development has the potential to help breeders in generating plants with defined architectural features to improve productivity. Plant translational research effort has steadily increased over the last decade due to the huge increase in the availability of crop genomic resources and Arabidopsis-based sequence annotation systems. However, a consistent gap between fundamental and applied science has yet to be filled. One critical point often brought up is the unreadiness of developmental biologists on one side to foresee agricultural applications for their discoveries, and of the breeders to exploit gene function studies to apply to candidate gene approaches when advantageous on the other. In this book, both developmental biologists and breeders make a special effort to reconcile research on the basic principles of plant development and organogenesis with its applications to crop production and genetic improvement. Fundamental and applied science contributions intertwine and chase each other, giving the reader different but complementary perspectives from only apparently distant corners of the same world.

The Regulatory Genome

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Publisher : Elsevier
ISBN 13 : 0080455573
Total Pages : 303 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis The Regulatory Genome by : Eric H. Davidson

Download or read book The Regulatory Genome written by Eric H. Davidson and published by Elsevier. This book was released on 2010-07-19 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene regulatory networks are the most complex, extensive control systems found in nature. The interaction between biology and evolution has been the subject of great interest in recent years. The author, Eric Davidson, has been instrumental in elucidating this relationship. He is a world renowned scientist and a major contributor to the field of developmental biology. The Regulatory Genome beautifully explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences. New insights into the mechanisms of body plan evolution are derived from considerations of the consequences of change in developmental gene regulatory networks. Examples of crucial evidence underscore each major concept. The clear writing style explains regulatory causality without requiring a sophisticated background in descriptive developmental biology. This unique text supersedes anything currently available in the market. The only book in the market that is solely devoted to the genomic regulatory code for animal development Written at a conceptual level, including many novel synthetic concepts that ultimately simplify understanding Presents a comprehensive treatment of molecular control elements that determine the function of genes Provides a comparative treatment of development, based on principles rather than description of developmental processes Considers the evolutionary processes in terms of the structural properties of gene regulatory networks Includes 42 full-color descriptive figures and diagrams

Mammalian Development

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Publisher :
ISBN 13 : 9781936113248
Total Pages : 0 pages
Book Rating : 4.1/5 (132 download)

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Book Synopsis Mammalian Development by : Patrick P. L. Tam

Download or read book Mammalian Development written by Patrick P. L. Tam and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A subject collection from Cold Spring Harbor perspectives in biology."

Branching Morphogenesis

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Publisher : Springer Science & Business Media
ISBN 13 : 0387308733
Total Pages : 255 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Branching Morphogenesis by : Jamie Davies

Download or read book Branching Morphogenesis written by Jamie Davies and published by Springer Science & Business Media. This book was released on 2007-03-20 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.

Gradients and Tissue Patterning

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Publisher : Academic Press
ISBN 13 : 0128127910
Total Pages : 500 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Gradients and Tissue Patterning by :

Download or read book Gradients and Tissue Patterning written by and published by Academic Press. This book was released on 2020-03-04 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gradients and Tissue Patterning, Volume 137 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series Includes the latest information on gradients and tissue patterning

Plant Promoters and Transcription Factors

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Publisher : Springer Science & Business Media
ISBN 13 : 3540480374
Total Pages : 279 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Plant Promoters and Transcription Factors by : Lutz Nover

Download or read book Plant Promoters and Transcription Factors written by Lutz Nover and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: The control of plant gene expression at the transcriptional level is the main subject of this volume. Genetics, molecular biology and gene technology have dramatically improved our knowledge of this event. The functional analysis of promoters and transcription factors provides more and more insights into the molecular anatomy of initiation complexes assembled from RNA polymerase and the multiplicity of helper and control proteins. Formation of specific DNA-protein complexes - activating or repressing transcription - is the crux of developmental or environmental control of gene expression. The book presents an up-to-date, critical overview of this rapidly advancing field.

Bioinformatics Research and Applications

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Publisher : Springer
ISBN 13 : 364213078X
Total Pages : 263 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Bioinformatics Research and Applications by : Mark Borodovsky

Download or read book Bioinformatics Research and Applications written by Mark Borodovsky and published by Springer. This book was released on 2010-05-10 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume constitutes the refereed proceedings of the 6th International Symposium on Bioinformatics Research and Applications, ISBRA 2010, held in Storrs, CT, USA, in May 2010. The 20 revised full papers and 6 invited talks presented were carefully reviewed and selected out of 57 submissions. Topics presented span all areas of bioinformatics and computational biology, including the development of experimental or commercial systems.

Murine Homeobox Gene Control of Embryonic Patterning and Organogenesis

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Publisher : Elsevier
ISBN 13 : 0080497357
Total Pages : 265 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Murine Homeobox Gene Control of Embryonic Patterning and Organogenesis by : Thomas Lufkin

Download or read book Murine Homeobox Gene Control of Embryonic Patterning and Organogenesis written by Thomas Lufkin and published by Elsevier. This book was released on 2003-12-03 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first homeobox gene was molecular cloned nearly two decades ago, and since that time tremendous progress has been made in our understanding of the distribution of homeobox genes in the genomes of many animal species and the common functional role the encoded homeodomains play in cell-type specification, morphogenesis and development. The amino acid sequence of the homeodomain, as well as the presence of other conserved protein domains, has allowed the classification of homeodomain-containing proteins (homeoproteins) into over thirty separate families (e.g. Hox, Dlx, Msx, Otx, Hmx, Cdx etc.). In many cases a single gene has been shown to fully direct the morphogenesis and development of a complex tissue, organ or even an entire body segment. Yet how this "master" regulatory ability of homeoproteins functions at the molecular level to a large degree still remains a mystery, in part owing to our limited understanding of the nature of both homeoprotein transcriptional cofactors and even more elusively, the downstream targets of homeoprotein function. In the reviews presented here it is limited primarily to what has been learned in vertebrate systems, principally focusing on the mouse, owing to the strengths of the technical approaches currently existing in murine developmental genetics that are not yet available to the same degree in other vertebrate species. Despite this mammalian predilection, a common thread to each of these reviews is the underlying importance of what has been learned about homeoprotein function in other animal species, particularly arthropods like Drosophila.

Evolution of Gene Regulatory Networks in Plant Development

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Publisher : Frontiers Media SA
ISBN 13 : 288945407X
Total Pages : 252 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Evolution of Gene Regulatory Networks in Plant Development by : Federico Valverde

Download or read book Evolution of Gene Regulatory Networks in Plant Development written by Federico Valverde and published by Frontiers Media SA. This book was released on 2018-02-15 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: During their life cycle plants undergo a wide variety of morphological and developmental changes. Impinging these developmental processes there is a layer of gene, protein and metabolic networks that are responsible for the initiation of the correct developmental transitions at the right time of the year to ensure plant life success. New omic technologies are allowing the acquisition of massive amount of data to develop holistic and integrative analysis to understand complex processes. Among them, Microarray, Next-generation Sequencing (NGS) and Proteomics are providing enormous amount of data from different plant species and developmental stages, thus allowing the analysis of gene networks globally. Besides, the comparison of molecular networks from different species is providing information on their evolutionary history, shedding light on the origin of many key genes/proteins. Moreover, developmental processes are not only genetically programed but are also affected by internal and external signals. Metabolism, light, hormone action, temperature, biotic and abiotic stresses, etc. have a deep effect on developmental programs. The interface and interplay between these internal and external circuits with developmental programs can be unraveled through the integration of systematic experimentation with the computational analysis of the generated omics data (Molecular Systems Biology). This Research Topic intends to deepen in the different plant developmental pathways and how the corresponding gene networks evolved from a Molecular Systems Biology perspective. Global approaches for photoperiod, circadian clock and hormone regulated processes; pattern formation, phase-transitions, organ development, etc. will provide new insights on how plant complexity was built during evolution. Understanding the interface and interplay between different regulatory networks will also provide fundamental information on plant biology and focus on those traits that may be important for next-generation agriculture.