Assessing Ocular Toxicology in Laboratory Animals

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1627031642
Total Pages : 327 pages
Book Rating : 4.6/5 (27 download)

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Book Synopsis Assessing Ocular Toxicology in Laboratory Animals by : Andrea B Weir

Download or read book Assessing Ocular Toxicology in Laboratory Animals written by Andrea B Weir and published by Springer Science & Business Media. This book was released on 2012-12-04 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. Ocular Toxicity in Laboratory Animals provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes. The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, Ocular Toxicity in Laboratory Animals is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies.

Ophthalmic Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 9781439809983
Total Pages : 398 pages
Book Rating : 4.8/5 (99 download)

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Book Synopsis Ophthalmic Toxicology by : G. C. Y. Chiou

Download or read book Ophthalmic Toxicology written by G. C. Y. Chiou and published by CRC Press. This book was released on 1999-07-01 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and updates, this new edition of Ophthalmic Toxicology retains its uniqueness in covering all aspects of ophthalmic toxicology. With chapters from leading authorities incorporating the latest developments in the field, including a new chapter on the molecular basis of ophthalmic toxicity, this edition covers such topics as: *t

Ocular Pharmacology and Toxicology

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Author :
Publisher : Humana
ISBN 13 : 9781627037440
Total Pages : 0 pages
Book Rating : 4.0/5 (374 download)

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Book Synopsis Ocular Pharmacology and Toxicology by : Brian C. Gilger

Download or read book Ocular Pharmacology and Toxicology written by Brian C. Gilger and published by Humana. This book was released on 2013-11-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering ocular pharmacokinetics, pharmacodynamics, and toxicology, Ocular Pharmacology and Toxicology provides ophthalmologists, toxicologists, and pharmacologists with both an introduction to the proper methods for ocular pharmacology and toxicology as well as providing practical methodologies for conducting ocular studies. Expert authors have contributed detailed chapters on study design, analysis, and routes to regulatory approval for various types and routes of ophthalmic drugs. As a volume in the Methods in Pharmacology and Toxicology series, chapters feature the kind of in-depth specifics and implementation advice to ensure successful results. Practical and authoritative, Ocular Pharmacology and Toxicology serves as an ideal basis of training in the proper design and conduct of essential studies to accurately determine pharmacokinetics and ocular toxicity from the systemic, topical, periocular, or intraocular administration of drugs or compounds, from the use of ocular medical devices and from ocular surgical procedures.

Drug-induced Ocular Side Effects and Drug Interactions

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Author :
Publisher :
ISBN 13 :
Total Pages : 578 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Drug-induced Ocular Side Effects and Drug Interactions by : Frederick T. Fraunfelder

Download or read book Drug-induced Ocular Side Effects and Drug Interactions written by Frederick T. Fraunfelder and published by . This book was released on 1982 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Introduction to Basics of Pharmacology and Toxicology

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Author :
Publisher : Springer Nature
ISBN 13 : 9813360097
Total Pages : 1156 pages
Book Rating : 4.8/5 (133 download)

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Book Synopsis Introduction to Basics of Pharmacology and Toxicology by : Abialbon Paul

Download or read book Introduction to Basics of Pharmacology and Toxicology written by Abialbon Paul and published by Springer Nature. This book was released on 2021-03-13 with total page 1156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Clinical Ocular Toxicology

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Author :
Publisher : Saunders
ISBN 13 : 9781416046738
Total Pages : 370 pages
Book Rating : 4.0/5 (467 download)

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Book Synopsis Clinical Ocular Toxicology by : Frederick T. Fraunfelder

Download or read book Clinical Ocular Toxicology written by Frederick T. Fraunfelder and published by Saunders. This book was released on 2008 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by international authorities in ocular toxicology, including the Founder of The National Registry of Drug-Induced Side Effects and its current Director, this essential resource provides the clinically relevant information you need to effectively diagnose and manage herbal, chemical, and drug-related ocular problems. Comprehensive coverage of all drugs' generic and trade drug names, primary uses, ocular and systemic side effects, and clinical significance make this book - like its best-selling predecessor, Drug-Induced Ocular Side Effects - the ideal reference for quick, on-the-spot consultation. Leaders in the field provide need-to-know information on all aspects of ocular toxicology-all in one concise reference. Data from the National Registry of Drug Induced Ocular Side-Effects (Casey Eye Institute, Portland, OR) and the World Health Organization (Uppsala, Sweden) help you recognize and avoid drug-induced ocular side effects. A highly templated format makes retrieval of essential knowledge quick and easy. A wealth of full-color photographs provide vivid, visual diagnostic guidance. The latest information on approved medications helps you stay up to date and provide state-of-the-art care. Extensive coverage of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics gives you the knowledge you need to manage any challenge in ocular toxicology Authoritative guidance on ocular drugs and their use in pregnancy helps you safely manage the unique needs of these patients. The inclusion of the WHO classification system helps you determine whether a particular side effect is certain, probable, or likely to occur.

Clinical Ocular Pharmacology

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Author :
Publisher : Butterworth-Heinemann
ISBN 13 :
Total Pages : 1080 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Clinical Ocular Pharmacology by : Jimmy D. Bartlett

Download or read book Clinical Ocular Pharmacology written by Jimmy D. Bartlett and published by Butterworth-Heinemann. This book was released on 1995 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in the field, this comprehensive resource offers valuable information on the practical uses of drugs in primary eye care. Discussions of the pharmacology of ocular drugs such as anti-infective agents, anti-glaucoma drugs, and anti-allergy drugs lead to more in-depth information on ocular drugs used to treat a variety of disorders, including diseases of the eyelids, corneal diseases, ocular infections, and glaucoma. The book also covers ocular toxicology, focusing on drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies.

The Actions and Uses of Ophthalmic Drugs

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Author :
Publisher : Elsevier
ISBN 13 : 1483192040
Total Pages : 263 pages
Book Rating : 4.4/5 (831 download)

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Book Synopsis The Actions and Uses of Ophthalmic Drugs by : P. H. O'Connor Davies

Download or read book The Actions and Uses of Ophthalmic Drugs written by P. H. O'Connor Davies and published by Elsevier. This book was released on 2013-10-22 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Actions and Uses of Ophthalmic Drugs, Third Edition discuses the application and discrimination in the use of ophthalmic drugs. The book reviews the general pharmacological principles including drug nomenclature, pharmacological classification, pharmacokinetics, pharmacodynamics, and the use of these drugs. Ophthalmic drugs (cycloplegics, mydriatics, miotics) directly or indirectly, stimulate or inhibit a part of the autonomic nervous system connected to the intra-ocular muscles. The text investigates in detail the structure and function of this involuntary nervous system in the orbital region as it is affected by these drugs. The book explains the different drug classifications, their therapeutic and diagnostic purposes, including the ideal properties, indications, contra-indications, mode of action, or adverse effects of cycloplegics, of mydriatics, and of miotics. The book also describes the uses and characteristics of local anesthetics, stains, anti-infective agents, and miscellaneous agents (antihistamines, vasoconstrictors). The text explains the different types of contact lens solutions, application of ocular first aid, as well as, the possible adverse ocular reactions that can occur during ophthalmic drug therapy. This book is suitable for optometrists, pharmacists, pharmacologists, students and professors related to the discipline of optometry and general medicine.

Vaughan & Asbury's General Ophthalmology

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 0071593209
Total Pages : 486 pages
Book Rating : 4.0/5 (715 download)

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Book Synopsis Vaughan & Asbury's General Ophthalmology by : Paul Riordan-Eva

Download or read book Vaughan & Asbury's General Ophthalmology written by Paul Riordan-Eva and published by McGraw Hill Professional. This book was released on 2007-11-08 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic reference covering the diagnosis and treatment of all major ophthalmic diseases, as well as neurological and systemic diseases causing visual disturbance-extensively revised and updated Features State-of-the-art coverage of diagnostic techniques and therapeutic interventions for the full range of ophthalmic disorders Chapters dedicated to ophthalmic therapeutics, neuro-ophthalmology, ocular disorders associated with systemic diseases, immunologic diseases of the eye, pediatrics, genetics, preventive ophthalmology and lasers The latest clinical perspectives on such topics as: Treatments for age-related macular degeneration, including anti-VEGF therapies Intraocular steroid injections for retinal diseases Immunomodulatory drugs Treatment of corneal infections Medical and surgical treatments for glaucoma Detailed appendices on visual standards, practical factors in illumination, rehabilitation of the visually handicapped, and special services available to the blind Latest references

Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323674011
Total Pages : 597 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology E-Book by : Frederick T. Fraunfelder

Download or read book Drug-Induced Ocular Side Effects: Clinical Ocular Toxicology E-Book written by Frederick T. Fraunfelder and published by Elsevier Health Sciences. This book was released on 2020-06-21 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by global experts in the field of chemical- and drug-related ocular problems, Drug-Induced Ocular Side Effects, 8th Edition, provides need-to-know information on all aspects of ocular toxicology in one concise reference. This best-selling, user-friendly resource features a templated format, numerous full-color illustrations, and sweeping content updates throughout – all designed to eliminate uncertainty and ensure accurate diagnosis and treatment guidance. - Provides comprehensive coverage of drugs' generic and trade names, primary uses, ocular and systemic side effects, and clinical significance. - Features a unique side effect index, a new concise paperback format for portability, and clinical photos of ocular symptoms of adverse drug reactions. - Covers dozens of new drugs used in the U.S. and internationally, as well as extensive updates to drug registry information to ensure access to the latest data. - Includes expanded sections on how to follow patients with visual adverse drug reactions to chloroquine, hydroxychloroquine, isotretinoin, ethambutol, and more. Guidelines can be copied to use as patient handouts. - Offers extensive discussions of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics. - Provides the WHO classification system to help you determine whether a particular side effect is certain, probable, or likely to occur. - Ideal for ophthalmologists, optometrists, and busy clinicians in primary care, emergency medicine, and more – anyone who needs quick, on-the-spot consultation on ocular toxicology. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Ocular Toxicology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461518873
Total Pages : 365 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Ocular Toxicology by : Keith Green

Download or read book Ocular Toxicology written by Keith Green and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: On behalf of the editorial board and the organizing committee of the 4th congress of the International Society of Ocular Toxicology (I SOT), held in AnnecyNeyrier du Lac, France, October 9 -13, 1994, we are pleased to present to the ocular toxicology community this indexed volume of our congress proceedings. The 4th congress was designed primarily to facilitate and update the knowledge in ocular electrophysiology and ocular pharmacokinetics, in both the clinical and preclinical aspects. The outcome of this 4th congress, established in this volume, is a useful contribution to the meth odology in both fields and will hopefully assist in the evaluation and interpretation of ocular findings recorded in animal studies on drugs and other chemicals, in order to protect human health. Undoubtedly, work on the mechanisms of ocular toxicology in the process of pharmaceutical development must continue and these proceedings, embodying the presented papers, will add to the data base. The editors, the congress organizing committee and the members of the International Society of Ocular Toxicology thank the speakers who gave their time, knowledge, and expertise to assist us in this project. The following manuscripts contain the main substance of each of the platform presentations and, in some cases, much more. Moreover, our thanks go to all the participants coming from a range of background- regulatory, academic and industrial -for their attention and excellent contributions during the discussion.

Clinical Ocular Toxicology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1437719678
Total Pages : 383 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Clinical Ocular Toxicology E-Book by : Frederick T. Fraunfelder

Download or read book Clinical Ocular Toxicology E-Book written by Frederick T. Fraunfelder and published by Elsevier Health Sciences. This book was released on 2008-06-12 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by international authorities in ocular toxicology, including the Founder of The National Registry of Drug-Induced Side Effects and its current Director, this essential resource provides the clinically relevant information you need to effectively diagnose and manage herbal, chemical, and drug-related ocular problems. Comprehensive coverage of all drugs’ generic and trade drug names, primary uses, ocular and systemic side effects, and clinical significance make this book - like its best-selling predecessor, Drug-Induced Ocular Side Effects - the ideal reference for quick, on-the-spot consultation. Leaders in the field provide need-to-know information on all aspects of ocular toxicology—all in one concise reference. Data from the National Registry of Drug Induced Ocular Side-Effects (Casey Eye Institute, Portland, OR) and the World Health Organization (Uppsala, Sweden) help you recognize and avoid drug-induced ocular side effects. A highly templated format makes retrieval of essential knowledge quick and easy. A wealth of full-color photographs provide vivid, visual diagnostic guidance. The latest information on approved medications helps you stay up to date and provide state-of-the-art care. Extensive coverage of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics gives you the knowledge you need to manage any challenge in ocular toxicology Authoritative guidance on ocular drugs and their use in pregnancy helps you safely manage the unique needs of these patients. The inclusion of the WHO classification system helps you determine whether a particular side effect is certain, probable, or likely to occur.

TOXICOLOGY OF THE EYE

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Author :
Publisher : Charles C Thomas Publisher
ISBN 13 : 0398082154
Total Pages : 1619 pages
Book Rating : 4.3/5 (98 download)

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Book Synopsis TOXICOLOGY OF THE EYE by : W. Morton Grant

Download or read book TOXICOLOGY OF THE EYE written by W. Morton Grant and published by Charles C Thomas Publisher. This book was released on 1993-01-01 with total page 1619 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to present a synopsis of what is known about substances that have toxic properties injurious to the eyes, disturbing to vision, or affecting eyes in other unwanted ways. The coverage is truly comprehensive, encompassing local and systemic, acute and chronic, human and veterinary toxicology of the eye. The text summarizes mechanisms of injury, treatments, and other relevant knowledge for more than 3000 alphabetized substances - essentially all those on which public information is available. Also described are systemic side effects of ophthalmologic drugs, treatment of chemical burns of the eyes, and testing methods and species specificity for toxic effects on the eyes. Facilitating access to this prodigious amount of information is a large index that cross-references substances and effects, including numerous synonyms. This monumental work is a truly definitive text and a highly useful reference book that should be available to every ophthalmologist, emergency room, and medical library.

Clinical Ocular Pharmacology

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0750675764
Total Pages : 816 pages
Book Rating : 4.7/5 (56 download)

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Book Synopsis Clinical Ocular Pharmacology by : Jimmy D. Bartlett

Download or read book Clinical Ocular Pharmacology written by Jimmy D. Bartlett and published by Elsevier Health Sciences. This book was released on 2007-11-12 with total page 816 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by experts in the field, this comprehensive resource offers valuable information on the practical uses of drugs in primary eye care. Discussions of the pharmacology of ocular drugs such as anti-infective agents, anti-glaucoma drugs, and anti-allergy drugs lead to more in-depth information on ocular drugs used to treat a variety of disorders, including diseases of the eyelids, corneal diseases, ocular infections, and glaucoma. The book also covers ocular toxicology, focusing on drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies. A logical organization makes it easy to find essential information. Complete coverage of the basic fundamentals of pharmacology such as ocular drug delivery and ocular drug formulations. Comprehensive reviews of the pharmacology of specific classes of agents such as the cycloplegics, antiglaucoma drugs, anti-inflammatory drugs, ocular irrigating solutions, and contact lens care products. In-depth information on ocular drugs used in clinical practice, including chapters on drugs used to treat eyelid disorders, lacrimal diseases, conjunctiva diseases, corneal diseases, allergies, uveitis, postoperative cataract, retinal diseases, and glaucoma. Coverage of ocular toxicology, including drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies. Completely revised and updated content that reflects the latest advances in pharmacology. Updated information on post-operative drugs, including LASIK follow up medications. Expanded coverage in the chapters on Anti-infective Drugs, Anti-allergy Drugs and Decongestants, and Lubricants and Other Preparations of Ocular Surface Disease that includes the latest advancements in antibiotics and medications used to treat allergies and dry eye. A dosage quick reference guide on the inside front cover for quick and easy access. Information on the use of herbal medications.

Dermal and Ocular Toxicology

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Author :
Publisher : CRC Press
ISBN 13 : 1000159701
Total Pages : 682 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Dermal and Ocular Toxicology by : David W. Hobson

Download or read book Dermal and Ocular Toxicology written by David W. Hobson and published by CRC Press. This book was released on 2020-11-26 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermal and Ocular Toxicology: Fundamentals and Methods is a procedurally-oriented volume of detailed methods and practical examples discussing the dermal and ocular aspects of toxicology. The book is divided into a dermal section and an ocular section. Each section begins with a chapter on the anatomy and physiology of each organ system and then progresses to more specialized chapters discussing such topics as the toxicological pathology of each system, state-of-the-art in vitro and in vivo evaluatory procedures, statistical considerations for test design and data interpretation, and the utilization of test findings. Test methods are provided for acute dermal exposure effects, dermal hypersensitivity and photoallergy assessment, dermal and ocular 0.pharmacokinetics, skin flap and skin grafting techniques, and in vitro alternative methods. This book can be used as an instructional text or as a sourcebook for practicing toxicologists, pharmacologists, industrial hygienists, occupational health professionals, and graduate students.

Principles and Practice of Ophthalmology E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1437721117
Total Pages : 5689 pages
Book Rating : 4.4/5 (377 download)

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Book Synopsis Principles and Practice of Ophthalmology E-Book by : Daniel M. Albert

Download or read book Principles and Practice of Ophthalmology E-Book written by Daniel M. Albert and published by Elsevier Health Sciences. This book was released on 2008-02-27 with total page 5689 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inside the 3rd edition of this esteemed masterwork, hundreds of the most distinguished authorities from around the world provide today's best answers to every question that arises in your practice. They deliver in-depth guidance on new diagnostic approaches, operative technique, and treatment option, as well as cogent explanations of every new scientific concept and its clinical importance. With its new streamlined, more user-friendly, full-color format, this 3rd edition makes reference much faster, easier, and more versatile. More than ever, it's the source you need to efficiently and confidently overcome any clinical challenge you may face. Comprehensive, authoritative, and richly illustrated coverage of every scientific and clinical principle in ophthalmology ensures that you will always be able to find the guidance you need to diagnose and manage your patients' ocular problems and meet today's standards of care. Updates include completely new sections on "Refractive Surgery" and "Ethics and Professionalism"... an updated and expanded "Geneitcs" section... an updated "Retina" section featuring OCT imaging and new drug therapies for macular degeneration... and many other important new developments that affect your patient care. A streamlined format and a new, more user-friendly full-color design - with many at-a-glance summary tables, algorithms, boxes, diagrams, and thousands of phenomenal color illustrations - allows you to locate the assistance you need more rapidly than ever.

Clinical Atlas of Canine and Feline Ophthalmic Disease

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 1118840844
Total Pages : 336 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Clinical Atlas of Canine and Feline Ophthalmic Disease by : Douglas W. Esson

Download or read book Clinical Atlas of Canine and Feline Ophthalmic Disease written by Douglas W. Esson and published by John Wiley & Sons. This book was released on 2015-06-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Atlas of Canine and Feline Ophthalmic Disease provides an image-rich resource for diagnosing and treating ophthalmic conditions in clinical practice. • Presents more than 600 high-quality color photographs depicting commonly encountered ocular conditions in dogs and cats • Includes multiple images for each disease to show varying presentations • Organized for easy reference, covering the most commonly encountered conditions first • Designed for daily use in the busy clinical setting, allowing practitioners to quickly find and compare images as they see cases • Provides a concise summary of the most clinically relevant information on diagnosing and managing ophthalmic disease