Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancer - Volume II

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Publisher : Frontiers Media SA
ISBN 13 : 2832507387
Total Pages : 793 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancer - Volume II by : Liang Cheng

Download or read book Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancer - Volume II written by Liang Cheng and published by Frontiers Media SA. This book was released on 2022-11-29 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancers and Diseases

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Publisher : Frontiers Media SA
ISBN 13 : 2889718069
Total Pages : 769 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancers and Diseases by : Liang Cheng

Download or read book Omics Data Integration towards Mining of Phenotype Specific Biomarkers in Cancers and Diseases written by Liang Cheng and published by Frontiers Media SA. This book was released on 2022-02-16 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Evolution of Translational Omics

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Publisher : National Academies Press
ISBN 13 : 0309224187
Total Pages : 354 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Evolution of Translational Omics by : Institute of Medicine

Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Multi-omic Data Integration in Oncology

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Multi-omic Data Integration in Oncology by : Chiara Romualdi

Download or read book Multi-omic Data Integration in Oncology written by Chiara Romualdi and published by . This book was released on 2020 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

DNA Methylation

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Publisher : Birkhäuser
ISBN 13 : 3034891180
Total Pages : 581 pages
Book Rating : 4.0/5 (348 download)

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Book Synopsis DNA Methylation by : J. Jost

Download or read book DNA Methylation written by J. Jost and published by Birkhäuser. This book was released on 2013-11-11 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: The occurrence of 5-methylcytosine in DNA was first described in 1948 by Hotchkiss (see first chapter). Recognition of its possible physiologi cal role in eucaryotes was first suggested in 1964 by Srinivasan and Borek (see first chapter). Since then work in a great many laboratories has established both the ubiquity of 5-methylcytosine and the catholicity of its possible regulatory function. The explosive increase in the number of publications dealing with DNA methylation attests to its importance and makes it impossible to write a comprehensive coverage of the literature within the scope of a general review. Since the publication of the 3 most recent books dealing with the subject (DNA methylation by Razin A. , Cedar H. and Riggs A. D. , 1984 Springer Verlag; Molecular Biology of DNA methylation by Adams R. L. P. and Burdon R. H. , 1985 Springer Verlag; Nucleic Acids Methylation, UCLA Symposium suppl. 128, 1989) considerable progress both in the techniques and results has been made in the field of DNA methylation. Thus we asked several authors to write chapters dealing with aspects of DNA methyla tion in which they are experts. This book should be most useful for students, teachers as well as researchers in the field of differentiation and gene regulation. We are most grateful to all our colleagues who were willing to spend much time and effort on the publication of this book. We also want to express our gratitude to Yan Chim Jost for her help in preparing this book.

Molecular Epidemiology

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Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Epidemiology by : Paul A. Schulte

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Multi-omic Data Integration in Oncology

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Publisher : Frontiers Media SA
ISBN 13 : 2889661512
Total Pages : 187 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Multi-omic Data Integration in Oncology by : Chiara Romualdi

Download or read book Multi-omic Data Integration in Oncology written by Chiara Romualdi and published by Frontiers Media SA. This book was released on 2020-12-03 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Data Analytics in Bioinformatics

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Publisher : John Wiley & Sons
ISBN 13 : 111978560X
Total Pages : 433 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Data Analytics in Bioinformatics by : Rabinarayan Satpathy

Download or read book Data Analytics in Bioinformatics written by Rabinarayan Satpathy and published by John Wiley & Sons. This book was released on 2021-01-20 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Machine learning techniques are increasingly being used to address problems in computational biology and bioinformatics. Novel machine learning computational techniques to analyze high throughput data in the form of sequences, gene and protein expressions, pathways, and images are becoming vital for understanding diseases and future drug discovery. Machine learning techniques such as Markov models, support vector machines, neural networks, and graphical models have been successful in analyzing life science data because of their capabilities in handling randomness and uncertainty of data noise and in generalization. Machine Learning in Bioinformatics compiles recent approaches in machine learning methods and their applications in addressing contemporary problems in bioinformatics approximating classification and prediction of disease, feature selection, dimensionality reduction, gene selection and classification of microarray data and many more.

Bioinformatics Analysis of Omics Data for Biomarker Identification in Clinical Research

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Publisher : Frontiers Media SA
ISBN 13 : 2889716635
Total Pages : 574 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Bioinformatics Analysis of Omics Data for Biomarker Identification in Clinical Research by : Lixin Cheng

Download or read book Bioinformatics Analysis of Omics Data for Biomarker Identification in Clinical Research written by Lixin Cheng and published by Frontiers Media SA. This book was released on 2022-01-10 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Machine Learning and Knowledge Discovery in Databases

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Publisher : Springer Science & Business Media
ISBN 13 : 354087478X
Total Pages : 714 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Machine Learning and Knowledge Discovery in Databases by : Walter Daelemans

Download or read book Machine Learning and Knowledge Discovery in Databases written by Walter Daelemans and published by Springer Science & Business Media. This book was released on 2008-09-04 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the joint conference on Machine Learning and Knowledge Discovery in Databases: ECML PKDD 2008, held in Antwerp, Belgium, in September 2008. The 100 papers presented in two volumes, together with 5 invited talks, were carefully reviewed and selected from 521 submissions. In addition to the regular papers the volume contains 14 abstracts of papers appearing in full version in the Machine Learning Journal and the Knowledge Discovery and Databases Journal of Springer. The conference intends to provide an international forum for the discussion of the latest high quality research results in all areas related to machine learning and knowledge discovery in databases. The topics addressed are application of machine learning and data mining methods to real-world problems, particularly exploratory research that describes novel learning and mining tasks and applications requiring non-standard techniques.

Artificial Intelligence

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Publisher : BoD – Books on Demand
ISBN 13 : 178923364X
Total Pages : 466 pages
Book Rating : 4.7/5 (892 download)

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Book Synopsis Artificial Intelligence by : Marco Antonio Aceves-Fernandez

Download or read book Artificial Intelligence written by Marco Antonio Aceves-Fernandez and published by BoD – Books on Demand. This book was released on 2018-06-27 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial intelligence (AI) is taking an increasingly important role in our society. From cars, smartphones, airplanes, consumer applications, and even medical equipment, the impact of AI is changing the world around us. The ability of machines to demonstrate advanced cognitive skills in taking decisions, learn and perceive the environment, predict certain behavior, and process written or spoken languages, among other skills, makes this discipline of paramount importance in today's world. Although AI is changing the world for the better in many applications, it also comes with its challenges. This book encompasses many applications as well as new techniques, challenges, and opportunities in this fascinating area.

Drug Repurposing in Cancer Therapy

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Publisher : Academic Press
ISBN 13 : 0128199032
Total Pages : 460 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Drug Repurposing in Cancer Therapy by : Kenneth K.W. To

Download or read book Drug Repurposing in Cancer Therapy written by Kenneth K.W. To and published by Academic Press. This book was released on 2020-07-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types

Artificial Intelligence in Design ’96

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Publisher : Springer Science & Business Media
ISBN 13 : 9400902794
Total Pages : 765 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Artificial Intelligence in Design ’96 by : John S. Gero

Download or read book Artificial Intelligence in Design ’96 written by John S. Gero and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Change is one of the most significant parameters in our society. Designers are amongst the primary change agents for any society. As a consequence design is an important research topic in engineering and architecture and related disciplines, since design is not only a means of change but is also one of the keystones to economic competitiveness and the fundamental precursor to manufacturing. The development of computational models founded on the artificial intelligence paradigm has provided an impetus for much of current design research -both computational and cognitive. These forms of design research have only been carried out in the last decade or so and in the temporal sense they are still immature. Notwithstanding this immaturity, noticeable advances have been made both in extending our understanding of design and in developing tools based on that understanding. Whilst many researchers in the field of artificial intelligence in design utilise ideas about how humans design as one source of concepts there is normally no attempt to model human designers. Rather the results of the research presented in this volume demonstrate approaches to increasing our understanding of design as a process.

Role of Biomarkers in Medicine

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Publisher : BoD – Books on Demand
ISBN 13 : 9535125052
Total Pages : 262 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Role of Biomarkers in Medicine by : Mu Wang

Download or read book Role of Biomarkers in Medicine written by Mu Wang and published by BoD – Books on Demand. This book was released on 2016-08-17 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of biomarkers in basic and clinical research has become routine in many areas of medicine. They are accepted as molecular signatures that have been well characterized and repeatedly shown to be capable of predicting relevant disease states or clinical outcomes. In Role of Biomarkers in Medicine, expert researchers in their individual field have reviewed many biomarkers or potential biomarkers in various types of diseases. The topics address numerous aspects of medicine, demonstrating the current conceptual status of biomarkers as clinical tools and as surrogate endpoints in clinical research. This book highlights the current state of biomarkers and will aid scientists and clinicians to develop better and more specific biomarkers for disease management.

The Handbook of Metabolic Phenotyping

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Publisher : Elsevier
ISBN 13 : 0128122943
Total Pages : 619 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis The Handbook of Metabolic Phenotyping by : John C. Lindon

Download or read book The Handbook of Metabolic Phenotyping written by John C. Lindon and published by Elsevier. This book was released on 2018-10-04 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics. Contains theoretical and practical explanations of all the main analytical chemistry techniques used in metabolic phenotyping Explores, in detail, the many diverse statistical approaches used in the field Offers practical tips for successfully conducting metabolic phenotyping studies Features reviews of all of the various fields of activity relating to human studies

Learning to Classify Text Using Support Vector Machines

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Publisher : Springer Science & Business Media
ISBN 13 : 1461509076
Total Pages : 218 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Learning to Classify Text Using Support Vector Machines by : Thorsten Joachims

Download or read book Learning to Classify Text Using Support Vector Machines written by Thorsten Joachims and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on ideas from Support Vector Machines (SVMs), Learning To Classify Text Using Support Vector Machines presents a new approach to generating text classifiers from examples. The approach combines high performance and efficiency with theoretical understanding and improved robustness. In particular, it is highly effective without greedy heuristic components. The SVM approach is computationally efficient in training and classification, and it comes with a learning theory that can guide real-world applications. Learning To Classify Text Using Support Vector Machines gives a complete and detailed description of the SVM approach to learning text classifiers, including training algorithms, transductive text classification, efficient performance estimation, and a statistical learning model of text classification. In addition, it includes an overview of the field of text classification, making it self-contained even for newcomers to the field. This book gives a concise introduction to SVMs for pattern recognition, and it includes a detailed description of how to formulate text-classification tasks for machine learning.

Drug Repurposing

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Publisher : BoD – Books on Demand
ISBN 13 : 1839685204
Total Pages : 236 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Drug Repurposing by : Farid A. Badria

Download or read book Drug Repurposing written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2020-12-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.