OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay PDF Online Free

Author :
Publisher : OECD Publishing
ISBN 13 : 9264366067
Total Pages : 37 pages
Book Rating : 4.2/5 (643 download)

DOWNLOAD NOW!


Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 470: Mammalian Erythrocyte Pig-a Gene Mutation Assay written by OECD and published by OECD Publishing. This book was released on 2022-06-30 with total page 37 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the phosphatidylinositol glycan class A gene (Pig-a), as a reporter of somatic-cell gene mutation. In vivo gene mutation tests, such as the Pig-a assay, are especially relevant for assessing mutagenicity because physiological factors, such as absorption of the test chemical from the site of exposure, distribution of the test chemical throughout the test system via systemic circulation, and in vivo metabolism and DNA repair processes, all contribute to the mutagenic responses.

Essentials of Pharmatoxicology in Drug Research, Volume 1

Download Essentials of Pharmatoxicology in Drug Research, Volume 1 PDF Online Free

Author :
Publisher : Elsevier
ISBN 13 : 044315841X
Total Pages : 754 pages
Book Rating : 4.4/5 (431 download)

DOWNLOAD NOW!


Book Synopsis Essentials of Pharmatoxicology in Drug Research, Volume 1 by : Rakesh Kumar Tekade

Download or read book Essentials of Pharmatoxicology in Drug Research, Volume 1 written by Rakesh Kumar Tekade and published by Elsevier. This book was released on 2023-03-23 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicity and Toxicodynamics, Volume One in the Essentials of Pharmatoxicology in Drug Research series provides an overview on the essentials of toxicology, risk assessment and the mechanisms. Topics discussed include the types of cellular responses to chemical toxicants, mechanisms of drug toxicity, and their relevance to pharmaceutical product development. The book examines omics and computer-aided technologies for mechanistic and predictive toxicology and covers state-of-art testing in the evaluation of detrimental pathways, dose selection in toxicity studies, as well as the role of regulatory agencies in toxicity studies. In addition, there is also discussion on clinical interventions such as pharmacotherapy and managed care strategies for acute poisoning. This volume is a valuable resource to those learning more about the drug development process related to toxicology and those who want to get an update on newer concepts on the toxicology aspect of drug research. - Examines toxicological risk assessment in drug research - Discusses toxicity mechanisms - Covers risk assessment and the use of omics and computational technologies in mechanistic and predictive toxicology - Offers clinical interventions and managed care as a result of toxic injury and acute poisoning

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 474: Mammalian Erythrocyte Micronucleus Test

Download OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 474: Mammalian Erythrocyte Micronucleus Test PDF Online Free

Author :
Publisher : OECD Publishing
ISBN 13 : 9264264760
Total Pages : 21 pages
Book Rating : 4.2/5 (642 download)

DOWNLOAD NOW!


Book Synopsis OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 474: Mammalian Erythrocyte Micronucleus Test by : OECD

Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 474: Mammalian Erythrocyte Micronucleus Test written by OECD and published by OECD Publishing. This book was released on 2016-07-29 with total page 21 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mammalian in vivo micronucleus test is used for the detection of damage induced by the test substance to the chromosomes or the mitotic apparatus of erythroblasts, by analysis of erythrocytes as sampled in bone marrow and/or peripheral blood cells of animals, usually rodents (mice or rats).

Test No. 489: In Vivo Mammalian Alkaline Comet Assay

Download Test No. 489: In Vivo Mammalian Alkaline Comet Assay PDF Online Free

Author :
Publisher : OECD Publishing
ISBN 13 : 9264224173
Total Pages : 25 pages
Book Rating : 4.2/5 (642 download)

DOWNLOAD NOW!


Book Synopsis Test No. 489: In Vivo Mammalian Alkaline Comet Assay by : OECD

Download or read book Test No. 489: In Vivo Mammalian Alkaline Comet Assay written by OECD and published by OECD Publishing. This book was released on 2014-09-26 with total page 25 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vivo alkaline single cell gel electrophoresis assay, also called alkaline Comet Assay is a method measuring DNA strand breaks in eukaryotic cells.

Toxicological Profile for Chloromethane

Download Toxicological Profile for Chloromethane PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Toxicological Profile for Chloromethane by :

Download or read book Toxicological Profile for Chloromethane written by and published by . This book was released on 1998 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetic Toxicology

Download Genetic Toxicology PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 9780849388156
Total Pages : 508 pages
Book Rating : 4.3/5 (881 download)

DOWNLOAD NOW!


Book Synopsis Genetic Toxicology by : Albert P. Li

Download or read book Genetic Toxicology written by Albert P. Li and published by CRC Press. This book was released on 1991-03-27 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic Toxicology is a comprehensive book covering the historical perspective of genetic toxicology; basic mechanisms of mutations and chromosomal effects; health consequences of genetic damage, including cancer and inheritable mutations; properties of physical, chemical, and biological mutagens; risk assessment of human exposure to genotoxicants; and the current position of some government regulatory agencies in the United States on the issues of genetic toxicology. The book will be a useful reference for students and researchers in toxicology, genetics, cancer biology, and medicine who are interested in the basic and applied principles of genetic toxicology. It will also benefit industrial toxicologists, products registration specialists, and government regulatory specialists with responsibility for the safety evaluation of industrial and environmental agents.

Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances

Download Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances PDF Online Free

Author :
Publisher : World Health Organization
ISBN 13 :
Total Pages : 696 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!


Book Synopsis Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Some Chemicals that Cause Tumours of the Kidney Or Urinary Bladder in Rodents and Some Other Substances written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 1999 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Allyl isothiocyanate; ortho-Anisidine; Atrazine; Butyl benzyl phthalate; Chloroform; Chlorothalonil;Cyclamates;Dichlorobenzenes;Hexachlorobutadiene; Hexachloroethane; d-Limonene; Melamine; Methyl tert-butyl ether; Nitrilotriaceticacid andits salts;Paracetamol; ortho-Phenylphenol and its sodium salt; Potassium bromate ;Quercetin; Saccharin and its salts;Simazine

Guidelines for Canadian Drinking Water Quality

Download Guidelines for Canadian Drinking Water Quality PDF Online Free

Author :
Publisher :
ISBN 13 : 9780660460239
Total Pages : 0 pages
Book Rating : 4.4/5 (62 download)

DOWNLOAD NOW!


Book Synopsis Guidelines for Canadian Drinking Water Quality by :

Download or read book Guidelines for Canadian Drinking Water Quality written by and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Malathion is a registered insecticide and acaricide used on a wide variety of sites including agricultural and non-agricultural sites. In 2018 (the most recent year for which data are available), over 25 000 kg of malathion was sold in Canada. Malathion may be released into surface water or soil as runoff from the application site. Malathion is not usually found in drinking water sources in Canada. Low levels of malathion have been found in several Canadian provinces. The maximum reported concentrations are well below the MAC. Malathion is rarely detected in foods"--Executive summary.

Soil Ecotoxicology

Download Soil Ecotoxicology PDF Online Free

Author :
Publisher : CRC Press
ISBN 13 : 9781566701341
Total Pages : 406 pages
Book Rating : 4.7/5 (13 download)

DOWNLOAD NOW!


Book Synopsis Soil Ecotoxicology by : Joseph Tarradellas

Download or read book Soil Ecotoxicology written by Joseph Tarradellas and published by CRC Press. This book was released on 1996-12-23 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Soils are receptacles for a wide range of hazardous chemicals generated by human activities. Whether or not this contamination is deliberate, accurate toxicity assessments are important for health and economic reasons. Soil Ecotoxicology discusses the sources, fate, and transport of hazardous chemicals in soils. The fate (biodegradation and modeling) and the potential impacts of pesticides on soil ecosystems are emphasized, and methodologies for performing toxicity assessments are provided.

Nutritional Antioxidant Therapies: Treatments and Perspectives

Download Nutritional Antioxidant Therapies: Treatments and Perspectives PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 3319676253
Total Pages : 572 pages
Book Rating : 4.3/5 (196 download)

DOWNLOAD NOW!


Book Synopsis Nutritional Antioxidant Therapies: Treatments and Perspectives by : Kaïs Hussain Al-Gubory

Download or read book Nutritional Antioxidant Therapies: Treatments and Perspectives written by Kaïs Hussain Al-Gubory and published by Springer. This book was released on 2018-03-10 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a collection of expert reviews on the use of plant-based antioxidant therapies in disease prevention and treatment. Topics discussed include the uses of plant and nutritional antioxidants in the contexts of reproductive health and prenatal development, healthcare and aging, noncommunicable chronic diseases, and environmental pollution. The text is complemented by a wealth of color figures and summary tables.

Environmental Biotechnology Volume 4

Download Environmental Biotechnology Volume 4 PDF Online Free

Author :
Publisher : Springer Nature
ISBN 13 : 3030777952
Total Pages : 269 pages
Book Rating : 4.0/5 (37 download)

DOWNLOAD NOW!


Book Synopsis Environmental Biotechnology Volume 4 by : K. M. Gothandam

Download or read book Environmental Biotechnology Volume 4 written by K. M. Gothandam and published by Springer Nature. This book was released on 2021-09-24 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the production of bioplastic from various raw materials and recycling wastewater into useful bioproducts by bacteria. In addition, it also addresses the recent advancement in pest control in rice plants, different methods to analyse genotoxicity on soil samples and the effect of phytocompounds on acrylamide-induced toxicity in Drosophilla. Interestingly, this book also discusses mesoporous silica nanoparticles' role as nanocarrier material for inhibiting the cancer cell, especially breast cancer and various biotechnological applications of marine fungal exopolysaccharides.

Inorganic Chromium(III) Compounds

Download Inorganic Chromium(III) Compounds PDF Online Free

Author :
Publisher : World Health Organization
ISBN 13 : 9241530766
Total Pages : 101 pages
Book Rating : 4.2/5 (415 download)

DOWNLOAD NOW!


Book Synopsis Inorganic Chromium(III) Compounds by : Tiina Santonen

Download or read book Inorganic Chromium(III) Compounds written by Tiina Santonen and published by World Health Organization. This book was released on 2009 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document on inorganic chromium (III) compounds provides summaries of the relevant scientific information concerning the potential effects of these chemicals upon human health and/or the environment. Chemical safety cards on the most common inorganic trivalent chromium compounds are reproduced in this document.

Ecotoxicology of Antifouling Biocides

Download Ecotoxicology of Antifouling Biocides PDF Online Free

Author :
Publisher : Springer Science & Business Media
ISBN 13 : 4431857095
Total Pages : 431 pages
Book Rating : 4.4/5 (318 download)

DOWNLOAD NOW!


Book Synopsis Ecotoxicology of Antifouling Biocides by : Takaomi Arai

Download or read book Ecotoxicology of Antifouling Biocides written by Takaomi Arai and published by Springer Science & Business Media. This book was released on 2009-01-29 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organotin compounds, used as antifouling biocides since 1960, are chemical compounds that act as endocrine disrupters. It is not known how organotin compounds cause hormone disturbance, however, and many questions remain about their effect on aquatic organisms. Studies on organotin compounds have recently evolved, with many new findings reported. Following a worldwide ban on organotin compounds in 2008, alternative compounds will mainly be used, with the potential for coastal areas to become contaminated, causing, among other effects, cholinesterase inhibition in aquatic organisms. Use of alternative compounds must be controlled to avoid such errors. These and other findings are described and concisely summarized in this book, providing a useful reference in countries where alternative biocides are being considered. Included are studies on the effects on marine organisms, making this book an excellent aid to experts in environmental chemistry, to government organizations, and to students.

Mushrooms traded as food. Vol II sec 2

Download Mushrooms traded as food. Vol II sec 2 PDF Online Free

Author :
Publisher : Nordic Council of Ministers
ISBN 13 : 9289327057
Total Pages : 474 pages
Book Rating : 4.2/5 (893 download)

DOWNLOAD NOW!


Book Synopsis Mushrooms traded as food. Vol II sec 2 by : Jørn Gry

Download or read book Mushrooms traded as food. Vol II sec 2 written by Jørn Gry and published by Nordic Council of Ministers. This book was released on 2014-07-11 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mushrooms recognised as edible have been collected and cultivated for many years. In the Nordic countries, the interest for eating mushrooms has increased. In order to ensure that Nordic consumers will be supplied with safe and well characterised, edible mushrooms on the market, this publication aims at providing tools for the in-house control of actors producing and trading mushroom products. The report is divided into two volumes: a. Volume I: “Mushrooms traded as food - Nordic questionnaire and guidance list for edible mushrooms suitable for commercial marketing b. Volume II: Background information, with general information in section 1 and in section 2, risk assessments of more than 100 mushroom species All mushrooms on the lists have been risk assessed regarding their safe use as food, in particular focusing on their potential content of bioactive constituents.

Toxicological Profile for Aldrin/dieldrin :.

Download Toxicological Profile for Aldrin/dieldrin :. PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (126 download)

DOWNLOAD NOW!


Book Synopsis Toxicological Profile for Aldrin/dieldrin :. by :

Download or read book Toxicological Profile for Aldrin/dieldrin :. written by and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes

Download Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes PDF Online Free

Author :
Publisher : OECD Publishing
ISBN 13 : 9264243089
Total Pages : 18 pages
Book Rating : 4.2/5 (642 download)

DOWNLOAD NOW!


Book Synopsis Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes by : OECD

Download or read book Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes written by OECD and published by OECD Publishing. This book was released on 2015-07-28 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: The in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances. In this test, the used genetic endpoints measure mutation at hypoxanthine-guanine phosphoribosyl transferase (HPRT), and at a transgene of xanthineguanine phosphoribosyl ...

Integrating Emerging Technologies Into Chemical Safety Assessment

Download Integrating Emerging Technologies Into Chemical Safety Assessment PDF Online Free

Author :
Publisher : Council of CanadianAcademies
ISBN 13 : 1926558383
Total Pages : 324 pages
Book Rating : 4.9/5 (265 download)

DOWNLOAD NOW!


Book Synopsis Integrating Emerging Technologies Into Chemical Safety Assessment by : The Expert Panel on the Integrated Testing of Pesticides

Download or read book Integrating Emerging Technologies Into Chemical Safety Assessment written by The Expert Panel on the Integrated Testing of Pesticides and published by Council of CanadianAcademies. This book was released on 2012 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In May 2009, the Government of Canada, through the Pest Management Regulatory Agency (PMRA) of Health Canada, asked the Council of Canadian Academies to appoint an expert panel to answer the question, "What is the scientific status of the use of integrated testing strategies in the human and environmental regulatory risk assessment of pesticides?" The charge to the Panel was further specified in a series of sub-questions: [1] What is the state of the science of the tools and data sources associated with integrated testing strategies? [2] What is the current status of the use of integrated testing strategies for the risk assessment of pesticides, pharmaceuticals, industrial chemicals, and other chemical substances by regulatory agencies around the world? [3] Could there be potential impacts on the public's perception and confidence in regulatory risk assessment and risk management decisions for pesticides if integrated testing strategies were implemented?"--P. xiii-xiv.