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Ode Pde Alpha Synuclein Models For Parkinsons Disease
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Book Synopsis ODE/PDE α-synuclein Models for Parkinson's Disease by : William E. Schiesser
Download or read book ODE/PDE α-synuclein Models for Parkinson's Disease written by William E. Schiesser and published by Academic Press. This book was released on 2018-02-13 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: ODE/PDE Alpha-Synuclein Models for Parkinson's Disease discusses a mechanism for the evolution of Parkinson's Disease (PD) based on the dynamics of the protein a-synuclein, a monomer that has been implicated in this disease. Specifically, a-synuclein morphs and aggregates into a polymer that can interfere with functioning neurons and lead to neurodegenerative pathology. This book first demonstrates computer-based implementation of a prototype ODE/PDE model for the dynamics of the a-synuclein monomer and polymer, and then details the methodology for the numerical integration of ODE/PDE systems which can be applied to computer-based analyses of alternative models based on the reader's interest. This book facilitates immediate computer use for research without the necessity to first learn the basic concepts of numerical analysis for ODE/PDEs and programming algorithms - Includes PDE routines based on the method of lines (MOL) for computer-based implementation of ODE/PDE models - Offers transportable computer source codes for readers, with line-by-line code descriptions relating to the mathematical model and algorithms - Authored by a leading researcher and educator in ODE/PDE models
Book Synopsis Network Spread Models of Neurodegenerative Diseases by : Ashish Raj
Download or read book Network Spread Models of Neurodegenerative Diseases written by Ashish Raj and published by Frontiers Media SA. This book was released on 2019-04-18 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a real pleasure to introduce the excellent papers contributed by leading experts to our Research Topic proposing various network models of dementia spread. The focus is strongly on disease-specific mathematical modeling rather than general graph theory. The emerging field of network neuroscience visualizes the brain as a graph consisting of nodes representing regions and edges as connections between them. This complex network supports efficient communication along neural projections, but also, unfortunately, the transmission and progression of Alzheimer’s and other neurodegenerative disorders. If we could know the brain’s network organization, could we then predict how degenerative processes might develop on this network? As these papers demonstrate, the answer is, increasingly, yes.
Book Synopsis 5th International Conference on Biomedical Engineering in Vietnam by : Vo Van Toi
Download or read book 5th International Conference on Biomedical Engineering in Vietnam written by Vo Van Toi and published by Springer. This book was released on 2014-11-18 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the proceedings of the Fifth International Conference on the Development of Biomedical Engineering in Vietnam which was held from June 16-18, 2014 in Ho Chi Minh City. The volume reflects the progress of Biomedical Engineering and discusses problems and solutions. I aims identifying new challenges, and shaping future directions for research in biomedical engineering fields including medical instrumentation, bioinformatics, biomechanics, medical imaging, drug delivery therapy, regenerative medicine and entrepreneurship in medical devices.
Book Synopsis Adaptive Method of Lines by : A, Vande Wouwer
Download or read book Adaptive Method of Lines written by A, Vande Wouwer and published by CRC Press. This book was released on 2001-04-18 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: The general Method of Lines (MOL) procedure provides a flexible format for the solution of all the major classes of partial differential equations (PDEs) and is particularly well suited to evolutionary, nonlinear wave PDEs. Despite its utility, however, there are relatively few texts that explore it at a more advanced level and reflect the method's
Book Synopsis A Compendium of Partial Differential Equation Models by : William E. Schiesser
Download or read book A Compendium of Partial Differential Equation Models written by William E. Schiesser and published by Cambridge University Press. This book was released on 2009-03-16 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents numerical methods and computer code in Matlab for the solution of ODEs and PDEs with detailed line-by-line discussion.
Book Synopsis Dynamic Modeling of Transport Process Systems by : C. A. Silebi
Download or read book Dynamic Modeling of Transport Process Systems written by C. A. Silebi and published by Elsevier. This book was released on 2012-12-02 with total page 533 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a methodology for the development and computer implementation of dynamic models for transport process systems. Rather than developing the general equations of transport phenomena, it develops the equations required specifically for each new example application. These equations are generally of two types: ordinary differential equations (ODEs) and partial differential equations (PDEs) for which time is an independent variable. The computer-based methodology presented is general purpose and can be applied to most applications requiring the numerical integration of initial-value ODEs/PDEs. A set of approximately two hundred applications of ODEs and PDEs developed by the authors are listed in Appendix 8.
Book Synopsis Lead Compounds from Medicinal Plants for the Treatment of Cancer by : Christophe Wiart
Download or read book Lead Compounds from Medicinal Plants for the Treatment of Cancer written by Christophe Wiart and published by Academic Press. This book was released on 2012-10-22 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Kelley/DNA Repair in Cancer Therapy, 2012, 978-0-12-384999-1.
Book Synopsis The Numerical Method of Lines by : William E. Schiesser
Download or read book The Numerical Method of Lines written by William E. Schiesser and published by Elsevier. This book was released on 2012-07-27 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book on the numerical method of lines, a relatively new method for solving partial differential equations. The Numerical Method of Lines is also the first book to accommodate all major classes of partial differential equations. This is essentially an applications book for computer scientists. The author will separately offer a disk of FORTRAN 77 programs with 250 specific applications, ranging from "Shuttle Launch Simulation" to "Temperature Control of a Nuclear Fuel Rod."
Book Synopsis Posttraumatic Stress Disorder and Related Diseases in Combat Veterans by : Elspeth Cameron Ritchie
Download or read book Posttraumatic Stress Disorder and Related Diseases in Combat Veterans written by Elspeth Cameron Ritchie and published by Springer. This book was released on 2015-10-27 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book takes a case-based approach to addressing the challenges psychiatrists and other clinicians face when working with American combat veterans after their return from a war zone. Written by experts, the book concentrates on a wide variety of concerns associated with posttraumatic stress disorder (PTSD), including different treatments of PTSD. The text also looks at PTSD comorbidities, such as depression and traumatic brain injury (TBI) and other conditions masquerading as PTSD. Finally, the authors touch on other subjects concerning returning veterans, including pain, disability, facing the end of a career, sleep problems , suicidal thoughts, violence, , and mefloquine “toxidrome”. Each case study includes a case presentation, diagnosis and assessment, treatment and management, outcome and case resolution, and clinical pearls and pitfalls. Post-Traumatic Stress Disorder and Related Diseases in Combat Veterans is a valuable resource for civilian and military mental health practitioners, and primary care physicians on how to treat patients returning from active war zones.
Book Synopsis Computational Mathematics in Engineering and Applied Science by : W.E. Schiesser
Download or read book Computational Mathematics in Engineering and Applied Science written by W.E. Schiesser and published by CRC Press. This book was released on 2014-07-22 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Mathematics in Engineering and Applied Science provides numerical algorithms and associated software for solving a spectrum of problems in ordinary differential equations (ODEs), differential algebraic equations (DAEs), and partial differential equations (PDEs) that occur in science and engineering. It presents detailed examples, each
Book Synopsis Waking and the Reticular Activating System in Health and Disease by : Edgar Garcia-Rill
Download or read book Waking and the Reticular Activating System in Health and Disease written by Edgar Garcia-Rill and published by Academic Press. This book was released on 2015-04-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Waking and the Reticular Activating System in Health and Disease provides a comprehensive overview on the "activating properties of the RAS. In health, the RAS provides the basis against which we assess the external world, and in disease it distorts that world and shatters our self-image. This book describes the physiology of each process, how it is disturbed in each disorder, and what the most appropriate treatment should be. Dr. Garcia-Rill, along with contributions from leading specialists, discusses the understanding of the RAS as a system not only modulating waking, but also in charge of survival mechanisms such as fight vs flight responses and reflexes. The full spectrum of these functions helps explain the complexity of symptoms evident in such disorders as disparate as schizophrenia and Parkinson's disease. The book reviews the mechanisms that control waking and arousal, and especially how those mechanisms malfunction in certain neurological and psychiatric disorders. - First comprehensive overview on the RAS and its role in schizophrenia, major depression, autism, Parkinson's, Alzheimer's, and other neurologic and mental diseases - Offers a new way of thinking about brain function and the role of the RAS in our waking lives - Written by a leading translational neuroscience researcher with contributions by specialists in the field
Book Synopsis Computational Transport Phenomena by : W. E. Schiesser
Download or read book Computational Transport Phenomena written by W. E. Schiesser and published by Cambridge University Press. This book was released on 1997-08-13 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: A clear, user-oriented introduction to the subject of computational transport phenomena, first published in 1997.
Book Synopsis Bio-nanoimaging by : Vladimir N Uversky
Download or read book Bio-nanoimaging written by Vladimir N Uversky and published by Academic Press. This book was released on 2013-11-05 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers - Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties. - Provides practical examples of nanoimaging research from leading molecular biology, cell biology, protein chemistry, biotechnology, genetics, and pharmaceutical labs - Includes over 200 color images to illustrate the power of various nanoimaging technologies - Focuses on nanoimaging techniques applied to protein misfolding and aggregation in molecular medicine
Book Synopsis Immersive Analytics by : Kim Marriott
Download or read book Immersive Analytics written by Kim Marriott and published by Springer. This book was released on 2018-10-15 with total page 366 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immersive Analytics is a new research initiative that aims to remove barriers between people, their data and the tools they use for analysis and decision making. Here the aims of immersive analytics research are clarified, its opportunities and historical context, as well as providing a broad research agenda for the field. In addition, it is reviewed how the term immersion has been used to refer to both technological and psychological immersion, both of which are central to immersive analytics research.
Book Synopsis Sexual Dysfunction in Parkinson's Disease by :
Download or read book Sexual Dysfunction in Parkinson's Disease written by and published by Academic Press. This book was released on 2022-04-07 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sexual Dysfunction in Parkinson's Disease, Volume 182, the latest release in the International Review of Neurobiology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of trending and important topics, including Prevalence, clinical presentations and impact on relationship, Pathophysiology, Scales for assessing sexual dysfunction in Parkinson's disease, Diagnostic work up: Laboratory and biomarkers, Management strategies, ICD DDS and sex dysfunction, Non-motor fluctuations and sex dysfunction, Exploring Sexual Dysfunction in Care Homes, and The impact of non-motor symptoms burden on sexual functions. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the International Review of Neurobiology series - Updated release includes the latest information regarding Sexual Dysfunction in Parkinson's Disease
Book Synopsis Quantification of Brain Function Using PET by :
Download or read book Quantification of Brain Function Using PET written by and published by Elsevier. This book was released on 1996-07-17 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional imaging of the brain is one of the most rapidly advancing areas of neuroscience and Positron Emission Tomography (PET) plays a major role in this progress. This book provides a comprehensive overview of the current status of PET and state-of-the-art neuroimaging. It is comprised of summaries of the presentations by experts in the field. Topics covered include radiotracer selection, advances in instrumentation, image reconstruction and data analysis, and statistical mapping of brain activity. This book focuses on the accuracy of the functional image and the strategies for addressing clinical, scientific, and diagnostic questions.Covers the PET imaging process from tracer selection to analysis and interpretationContains 79 concise reports with abundant illustrationsThe definitive state-of-the-art book for functional neuroscience with PET
Book Synopsis Human Mesenchymal Stem Cells by : Mitchell Khan
Download or read book Human Mesenchymal Stem Cells written by Mitchell Khan and published by Nova Science Publishers. This book was released on 2021 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: "In Chapter 1, the COVID-19 pandemic and the damage mechanisms on the cellular level which can be ameliorated with the cellular therapies is thoroughly evaluated. Previous and ongoing stem cell clinical trial data from diseases with similar symptoms is gathered. All this accumulated data and current clinical trial results indicate that the cellular therapies could be the most effective treatment option for COVID-19 patients to ameliorate the damaged tissues and save lives. In Chapter 2, the authors examine activated mesenchymal stem cells for stroke repair. Stem Cell treatment has shown recovery in animal models of stroke, indicating an improved regenerative and repair potential. Though stem cells are still being used in clinical trials, there is no evidence that they enhance recovery in ischemic stroke patients. Nevertheless, the multipotent mesenchymal stem has widely been explored for stroke recovery. An'Activated MSC' as a therapeutic alternative to tackling ischemic stroke is proposed, thereby the activation of MSCs by cytokines, growth factors, hypoxia, pharmacological drugs, etc., could be a novel approach to improving stroke patients' responses to receiving MSCs. In Chapter 3, the potential benefits of in vitro culture of therapeutic stem cells in the presence of HB along with the ketogenic diet, whereby higher physiological concentrations of ketone bodies can be achieved in vivo, as an adjuvant to stem cell transplantation is assessed"--
