Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889455637
Total Pages : 247 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders by : Aasef G. Shaikh

Download or read book Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders written by Aasef G. Shaikh and published by Frontiers Media SA. This book was released on 2018-08-29 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eye movements provide rich source of information about brain functioning for neurologists and neuroscientists. They provide diagnostic clues, define, and localize motor and cognitive disorders. Objective eye movement assessments associated with clinical observation and genetic testing in neurodegenerative, neurometabolic, and neurogenetic diseases provide insight into their pathophysiology and disease mechanism. Finally the eye movements may be used for testing and following the response to therapies. The concrete value of studying eye movement stems from a number of advantages compared to the study of movements of axial or limb muscles. The eye movements are accessible to clinical inspection, they can be measured precisely, their interpretation is clear and therefore ocular motility examination has high localization value. There are several standardized tasks to study of each subclass of eye movements that are recognized for motor or cognitive behavior. Indeed the studies of eye movement had allowed test of motor and cognitive functions of the brain in a vast range of neurological disease. Both cortical and subcortical dysfunctions may be detected with the analysis of subclasses of eye movements and interpreted in association with other clinical, laboratory and neuroimaging features. The goal of this topic-focused volume of Frontiers in Neurology is to gather seminal studies, from well-known scientists and laboratories from across the world, delineating the features of eye movements and vestibular system in neurogenetic, neurometabolic, and neurodegenerative disorders. Such collection of articles, to our knowledge, is unique and never done in the past. The topics and the compilation will be of interest to broad groups of neuroscientists and neurologists for the reasons as follows: 1) Neurodegenerative diseases represent a large portion of neurological diseases encountered in neurological clinical practice. Eye movement changes may occur early in their course and may be specific, thus orienting the diagnosis. 2) Neurometabolic and neurogenetic conditions, although rare, show specific and characteristic eye movements that represent the hallmark of the disease. Such disorders often represent a pathologic model that helps to understand the normal functioning of specific brain regions and networks.

Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders

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Author :
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (136 download)

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Book Synopsis Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders by :

Download or read book Ocular Motor and Vestibular Function in Neurometabolic, Neurogenetic, and Neurodegenerative Disorders written by and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Eye movements provide rich source of information about brain functioning for neurologists and neuroscientists. They provide diagnostic clues, define, and localize motor and cognitive disorders. Objective eye movement assessments associated with clinical observation and genetic testing in neurodegenerative, neurometabolic, and neurogenetic diseases provide insight into their pathophysiology and disease mechanism. Finally the eye movements may be used for testing and following the response to therapies. The concrete value of studying eye movement stems from a number of advantages compared to the study of movements of axial or limb muscles. The eye movements are accessible to clinical inspection, they can be measured precisely, their interpretation is clear and therefore ocular motility examination has high localization value. There are several standardized tasks to study of each subclass of eye movements that are recognized for motor or cognitive behavior. Indeed the studies of eye movement had allowed test of motor and cognitive functions of the brain in a vast range of neurological disease. Both cortical and subcortical dysfunctions may be detected with the analysis of subclasses of eye movements and interpreted in association with other clinical, laboratory and neuroimaging features. The goal of this topic-focused volume of Frontiers in Neurology is to gather seminal studies, from well-known scientists and laboratories from across the world, delineating the features of eye movements and vestibular system in neurogenetic, neurometabolic, and neurodegenerative disorders. Such collection of articles, to our knowledge, is unique and never done in the past. The topics and the compilation will be of interest to broad groups of neuroscientists and neurologists for the reasons as follows: 1) Neurodegenerative diseases represent a large portion of neurological diseases encountered in neurological clinical practice. Eye movement changes may occur early in their course and may be specific, thus orienting the diagnosis. 2) Neurometabolic and neurogenetic conditions, although rare, show specific and characteristic eye movements that represent the hallmark of the disease. Such disorders often represent a pathologic model that helps to understand the normal functioning of specific brain regions and networks.

Advances in Translational Neuroscience of Eye Movement Disorders

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Author :
Publisher : Springer Nature
ISBN 13 : 3030314073
Total Pages : 513 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Advances in Translational Neuroscience of Eye Movement Disorders by : Aasef Shaikh

Download or read book Advances in Translational Neuroscience of Eye Movement Disorders written by Aasef Shaikh and published by Springer Nature. This book was released on 2020-01-03 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive book that reviews advances in ocular motor research on topics of general interest, rare, specialized or unique conditions, and pertinent basic neuroscience. A rare collection with contributions from basic neuroscientists, neurologists, and ophthalmologists. Includes dedicated chapters on mathematical models, pharmacotherapy, neuromodulation, motion perception, visual influence on eye movement, physiology of strabismus, and microsaccades. This book is dedicated to David Robinson - one of the pioneers of contemporary ocular motor and vestibular neuroscience.

Pediatric Neuro-Ophthalmology

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461384575
Total Pages : 692 pages
Book Rating : 4.4/5 (613 download)

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Book Synopsis Pediatric Neuro-Ophthalmology by : Michael C. Brodsky

Download or read book Pediatric Neuro-Ophthalmology written by Michael C. Brodsky and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Neuroophthalmology details the diagnostic criteria, current concepts of pathogenesis, neuroradiological correlates, and clinical management of a large group of neuroophthalmic disorders that present in childhood. Surprisingly distinct from neuroophthalmic disorders afflicting adults, this set of diseases falls between the cracks of most ophthalmology training, and thus, warrants a practical, clinical guide for the practitioner in ophthalmology - the neuroophthalmologist, pediatric ophthalmologist, general ophthalmologist - as well as neurologists and for residents. The authors, leading pediatric ophthalmologists, have taken this difficult subject matter and developed an accessible, user-friendly manual with a detailed approach to the recognition, differential diagnosis, and management of pediatric neuroophthalmologic disorders.

Eye Movement Disorders

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Publisher : Springer Science & Business Media
ISBN 13 : 9400933177
Total Pages : 276 pages
Book Rating : 4.4/5 (9 download)

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Book Synopsis Eye Movement Disorders by : E.A.C.M. Sanders

Download or read book Eye Movement Disorders written by E.A.C.M. Sanders and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is perhaps no area of neuro-ophthalmology that is advancing more rapidly with respect to an understanding of its anatomy and physiology than the ocular motor system. For this reason, it is difficult not only to keep up with the latest information concerning the basic mechanisms involved in the control of eye movements but also to remain up to date regarding the pathophysiology of specific disorders of eye movement. The material in this book is derived from a two-day course on eye movements held in The Netherlands in 1986. The course was designed as an introduction to the normal ocular motor system and to disorders of eye movements and was aimed toward orthoptists, ophthalmolo gists, optometrists, neurologists, and neurosurgeons. The chapters in this book were compiled by a trio of experts in the field of eye movements and contain discussions of anatomy and physiology of the ocular motor system, techniques of examination of patients with diplopia, and pathophysiology of specific disorders of ocular motility. Many of the authors of these chapters are among the most active investigators of eye movements in the world today, and their comments thus reflect the latest information in the field. This text is both basic and com prehensive and thus has something for everyone, from the student just beginning a study of the ocular motor system to the seasoned 'veteran' who wishes to know the latest information regarding central ocular motor control mechanisms. Neil R.

Neuroanatomy Text and Atlas, Fifth Edition

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Author :
Publisher : McGraw Hill Professional
ISBN 13 : 1259642496
Total Pages : 542 pages
Book Rating : 4.2/5 (596 download)

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Book Synopsis Neuroanatomy Text and Atlas, Fifth Edition by : John D. Martin

Download or read book Neuroanatomy Text and Atlas, Fifth Edition written by John D. Martin and published by McGraw Hill Professional. This book was released on 2019-12-22 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: A regional and functional approach to learning human neuroanatomy – enhanced by additional full-color illustrations and PowerPoint® slides of all images in the text for instructors! Neuroanatomy: Text and Atlas covers neuroanatomy from both a functional and regional perspective to provide an understanding of how the components of the central nervous system work together to sense the world around us, regulate body systems, and produce behavior. This trusted text thoroughly covers the sensory, motor, and integrative skills of the brains and presents an overview of the function in relation to structure and the locations of the major pathways and neuronal integrative regions. Neuroanatomy: Text and Atlas also teaches readers how to interpret the new wealth of human brain images by developing an understanding of the anatomical localization of brain function. The authoritative core content of myelin-stained histological sections is enhanced by informative line illustrations, angiography, and brain views produced by MRI, and other imaging technologies. • Revised and updated to reflect advances in clinical neuroanatomy and neural science • Full-color illustrations enrich the text, including many new to this edition • Chapters begin with a clinical case to illustrate the connections and functions of the key material • Chapters end with a series of multiple-choice review questions • NEW Online learning center will display brain views produced by MRI and PET • Increases knowledge of the regional and functional organization of the spinal cord and brain, one system at a time • Provides thorough coverage of the sensory, motor, and integrative systems of the brain, together with cerebral vasculature • Promotes understanding of the complex details of neuroanatomy needed for accurate interpretation of radiological image • Comprehensive atlas provides key views of the surface anatomy of the central nervous systems and photographs of myelin-stained sections in three anatomical planes • Includes learning aids such as clinical topics, boxes, chapter summaries, and a Glossary of key terms and structures

Clinical Neurology, 3Ed

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Publisher : CRC Press
ISBN 13 : 0340807989
Total Pages : 597 pages
Book Rating : 4.3/5 (48 download)

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Book Synopsis Clinical Neurology, 3Ed by : T.J. Fowler

Download or read book Clinical Neurology, 3Ed written by T.J. Fowler and published by CRC Press. This book was released on 2003-11-28 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of this concise but comprehensive textbook follows on from the highly-regarded earlier editions in providing the trainee and general physician with a better understanding of the principles of neurology. Retaining an emphasis on the core clinical skills of history taking and careful neurological examination, the new edition has been thoroughly revised and updated to take into account new developments in investigation and treatment. Particular areas of enhanced coverage include headache, expanded beyond migraine to cover other presentations, and multiple sclerosis. Completely new chapters discuss the increasing role of neurogenetics in the understanding and treatment of neurological disease, the importance of pain and its management and neurological complications associated with respiratory intensive care. Following the sad death of Dr. David Marsden, Dr John Scadding has joined the editorial team retaining the 'Queen Square' connection of earlier editions.

The Neuronal Ceroid Lipofuscinoses (Batten Disease)

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Author :
Publisher : OUP Oxford
ISBN 13 : 019101558X
Total Pages : 480 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis The Neuronal Ceroid Lipofuscinoses (Batten Disease) by : Sara Mole

Download or read book The Neuronal Ceroid Lipofuscinoses (Batten Disease) written by Sara Mole and published by OUP Oxford. This book was released on 2011-03-10 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The neuronal ceroid lipofuscinoses are an extremely rare group of inherited neurodegenerative diseases that primarily affect children. Core symptoms of these conditions typically include epilepsy, cognitive decline and visual failure. These diseases are so rare that professionals who come into contact with them need a consultative reference work that enables them to become expert, or identify who to contact for more details. Fully updated and revised, this second edition continues to be the definitive volume on this devastating group of disorders. Written by an international collection of authorities in the field, it provides invaluable advice on their diagnosis, patient care, and new treatments that are available. This new edition of the definitive reference text on the neuronal ceroid lipofuscinoses will prove useful for clinicians, family physicians, research scientists, diagnostic laboratories, families affected by the disease as well as by workers in industry planning translational research.

The Neurology of Eye Movements : Text and CD-ROM

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0198029705
Total Pages : 658 pages
Book Rating : 4.1/5 (98 download)

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Book Synopsis The Neurology of Eye Movements : Text and CD-ROM by : Departments of Neurology R. John Leigh Professor, Neuroscience Otolaryngology and Biomedical Engineering Case Western Reserve University University Hospitals and Veterans Affairs Medical Center Cleveland Ohio

Download or read book The Neurology of Eye Movements : Text and CD-ROM written by Departments of Neurology R. John Leigh Professor, Neuroscience Otolaryngology and Biomedical Engineering Case Western Reserve University University Hospitals and Veterans Affairs Medical Center Cleveland Ohio and published by Oxford University Press, USA. This book was released on 1999-08-26 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurology of Eye Movements provides clinicians with a synthesis of current scientific information that can be applied to the diagnosis and treatment of disorders of ocular motility. Basic scientists will also benefit from descriptions of how data from anatomical, electrophysiological, pharmacological, and imaging studies can be directly applied to the study of disease. By critically reviewing such basic studies, the authors build a conceptual framework that can be applied to the interpretation of abnormal ocular motor behavior at the bedside. These syntheses are summarized in displays, new figures, schematics and tables. Early chapters discuss the visual need and neural basis for each functional class of eye movements. Two large chapters deal with the evaluation of double vision and systematically evaluate how many disorders of the central nervous system affect eye movements. This edition has been extensively rewritten, and contains many new figures and an up-to-date section on the treatment of abnormal eye movements such as nystagmus. A major innovation has been the development of an option to read the book from a compact disc, make use of hypertext links (which bridge basic science to clinical issues), and view the major disorders of eye movements in over 60 video clips. This volume will provide pertinent, up-to-date information to neurologists, neuroscientists, ophthalmologists, visual scientists, otalaryngologists, optometrists, biomedical engineers, and psychologists.

Eye Tracking Methodology

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Publisher : Springer Science & Business Media
ISBN 13 : 1846286093
Total Pages : 336 pages
Book Rating : 4.8/5 (462 download)

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Book Synopsis Eye Tracking Methodology by : Andrew Duchowski

Download or read book Eye Tracking Methodology written by Andrew Duchowski and published by Springer Science & Business Media. This book was released on 2007-09-14 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the availability of cheap, fast, accurate and usable eye trackers, there is little information available on how to develop, implement and use these systems. This 2nd edition of the successful guide contains significant additional material on the topic and aims to fill that gap in the market by providing an accessible and comprehensive introduction. Additional key features of the 2nd edition include: Technical description of new (state-of-the-art) eye tracking technology; a complete whole new section describing experimental methodology including experimental design, empirical guidelines, and five case studies; and survey material regarding recent research publications.

Principles of Neurobiology

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Author :
Publisher : Garland Science
ISBN 13 : 1317553837
Total Pages : 696 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis Principles of Neurobiology by : Liqun Luo

Download or read book Principles of Neurobiology written by Liqun Luo and published by Garland Science. This book was released on 2015-07-14 with total page 696 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Neurobiology presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in

Traumatic Brain and Spinal Cord Injury

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Publisher : Cambridge University Press
ISBN 13 : 1107007437
Total Pages : 361 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Traumatic Brain and Spinal Cord Injury by : Cristina Morganti-Kossmann

Download or read book Traumatic Brain and Spinal Cord Injury written by Cristina Morganti-Kossmann and published by Cambridge University Press. This book was released on 2012-07-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents the most up-to-date clinical and experimental research in neurotrauma in an illustrated, accessible, comprehensive volume.

Recent insights into perceptual and motor skill learning (The computational and neural processes underlying perceptual and motor skill learning)

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Publisher : Frontiers Media SA
ISBN 13 : 2889194469
Total Pages : 133 pages
Book Rating : 4.8/5 (891 download)

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Book Synopsis Recent insights into perceptual and motor skill learning (The computational and neural processes underlying perceptual and motor skill learning) by : Lior Shmuelof

Download or read book Recent insights into perceptual and motor skill learning (The computational and neural processes underlying perceptual and motor skill learning) written by Lior Shmuelof and published by Frontiers Media SA. This book was released on 2015-03-18 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: Improvements in task performance following practice can occur as a result of changes in distinct cognitive and neural processes. In some cases, we can improve our performance by selecting a more successful behavior that is already part of our available repertoire. Skill learning, on the other hand, refers to a slower process that results in improving the ability to perform a behavior, i.e., it involves the acquisition of a behavior that was not available to the controller before training. Skill learning can take place both in the sensory and in the motor domains. Sensory skill acquisition in perceptual learning tasks is measured by improvements in sensory acuity through practice-induced changes in the sensitivity of relevant neural networks. Motor skill is harder to define as the term is used whenever a motor learning behavior improves along some dimension. Nevertheless, we have recently argued that as in perceptual learning, acuity is an integral component in motor skill learning. In this special topic we set out to integrate experimental and theoretical work on perceptual and motor skill learning and to stimulate a discussion regarding the similarities and differences between these two kinds of learning.

Neuroimaging, Part II

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Author :
Publisher : Newnes
ISBN 13 : 0702045381
Total Pages : 720 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Neuroimaging, Part II by :

Download or read book Neuroimaging, Part II written by and published by Newnes. This book was released on 2016-07-12 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroimaging, Part Two, a volume in The Handbook of Clinical Neurology series, illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This second volume covers imaging of the adult spine and peripheral nervous system, as well as pediatric neuroimaging. In addition, it provides an overview of the differential diagnosis of the most common imaging findings, such as ring enhancement on MRI, and a review of the indications for imaging in the most frequent neurological syndromes. The volume concludes with a review of neuroimaging in experimental animals and how it relates to neuropathology. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, with the entire field moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to the new horizon in the study of neurological disorders. Provides a relevant description of the technologies used in neuroimaging, such as computed tomography, magnetic resonance imaging, positron emission tomography, and several others Discusses the application of these techniques to the study of brain and spinal cord disease Explores the indications for the use of these techniques in various syndromes

Neurodevelopmental Disabilities

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Publisher : Springer Science & Business Media
ISBN 13 : 9400706278
Total Pages : 496 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Neurodevelopmental Disabilities by : Dilip R. Patel

Download or read book Neurodevelopmental Disabilities written by Dilip R. Patel and published by Springer Science & Business Media. This book was released on 2011-04-07 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Increasingly more and more children with developmental disabilities survive into adulthood. Pediatricians and other clinicians are called upon to care for an increasing number of children with developmental disabilities in their practice and thus there is a need for a practical guide specifically written for paediatricians and primary care clinicians that addresses major concepts of neurodevelopmental pediatrics. In the United States, the specialty training leading to a conjoint board certification by the American Board of Pediatrics and American Board of Psychiatry and Neurology, requires a total of 6 years of training (2 years of pediatrics, 1 year of neurology, 18 months of child neurology, 18 months of neurodevelopmental disabilities). As of December 2006, in the US, there were 241 pediatricians and 55 child neurologists certified in the subspecialty of Neurodevelopmental Disabilities. Thus most of the children with developmental disabilities are seen by pediatricians and therefore it is important for these pediatricians to be well informed of common issues in the field. The 60,000 or so pediatricians in the United States (and hundreds more in other countries) are the main target audience for a practical book on neurodevelopmental pediatrics.

Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic, Gaze Orienting Mechanisms and Disease

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Author :
Publisher : Academic Press
ISBN 13 : 0444642552
Total Pages : 426 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic, Gaze Orienting Mechanisms and Disease by :

Download or read book Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic, Gaze Orienting Mechanisms and Disease written by and published by Academic Press. This book was released on 2019-07-18 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical Modelling in Motor Neuroscience: State of the Art and Translation to the Clinic, Gaze Orienting Mechanisms and Disease, Volume 249, the latest release in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Sequential Bayesian updating, Maps and Sensorimotor Transformations for Eye-Head Gaze Shifts: Role of the Midbrain Superior Colliculus, Modeling Gaze Position-Dependent Opsoclonus, Eye Position-Dependent Opsoclonus in Mild Traumatic Brain Injury, Saccades in Parkinson's disease -- hypometric, slow, and maladaptive, Brainstem Neural Circuits for Fixation and Generation of Saccadic Eye Movements, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Brain Research series Includes the latest information on mathematical modeling in motor neuroscience

Horizons in Neuroscience Research

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Author :
Publisher : Nova Science Publishers
ISBN 13 : 9781634829670
Total Pages : 0 pages
Book Rating : 4.8/5 (296 download)

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Book Synopsis Horizons in Neuroscience Research by : Andres Costa

Download or read book Horizons in Neuroscience Research written by Andres Costa and published by Nova Science Publishers. This book was released on 2015-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The authors' of this book discuss the most recent advances in neuroscience research. The chapters include updated information on clinical and technical implementation of digital subtraction angiography (DSA) in stroke imaging; association between word display and executive functioning; the connectivity between the cerebellum and inferior frontal gyrus (IFG); the identification and validation of EEG, MRI and SPECT biomarkers for diagnosing, monitoring progression and predicting the onset of Alzheimer's disease (AD); an examination of the leptin receptor, a drive of adult neurogenesis that may treat Alzheimer's disease; the language of neurons and their clinical applications such as in deep brain stimulation; the use of folic acid and its intake by pregnant women to support both physiological changes in the mother and the optimal growth and development of the fetus and offspring; examples of the continuum of shapes and sizes of different dendritic spines, from simple to complex, observed in the human brain; an examination of spastic diplegia, the most common form of cerebral palsy; and the identification of new mechanisms of pharmacological effects of certain neurotropic peptides.