Novel Fast 4D Phase Contrast Velocity Mapping MRI Sequences and Their Application on Cardiovascular Hemodynamics

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ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (142 download)

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Book Synopsis Novel Fast 4D Phase Contrast Velocity Mapping MRI Sequences and Their Application on Cardiovascular Hemodynamics by : Ali Nahardani

Download or read book Novel Fast 4D Phase Contrast Velocity Mapping MRI Sequences and Their Application on Cardiovascular Hemodynamics written by Ali Nahardani and published by . This book was released on 2023 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: 4D-flow velocity mapping is a technique in magnetic resonance imaging (MRI) to quantify blood flow velocity in 3D space and over time. To increase accuracy, novel sequences have been developed to overcome its technical limitations, including the low signal-to-noise ratio (SNR), low velocity-to-noise ratio (VNR), background velocity fluctuations due to concomitant fields, and flow-related intra-voxel dephasing. However, for a long time, this field was almost untouched in preclinical imaging until Krämer et al. (2017) developed the self-gated ultra-short-echo 4D-flow (UTE-4D-flow) technique. Although UTE-4D-flow showed superior SNR and VNR compared to the conventional prospectively-gated Cartesian-4D-flow method, its total scan time was too long to be applied in routine practice, especially in bigger animals than mice. To shorten the total scan time and preserve SNR and VNR, we combined the concepts of UTE-4D-flow and Cartesian-4D-flow techniques, which resulted in a Stack-of-Stars 4D-flow (SoS-4D-flow) sequence. The in-vitro evaluations of the sequence proved that it benefited from an improved SNR, VNR, and background velocity bias compared to the Cartesian counterpart. Thereafter, we applied the sequence on rats by integrating it into a prospective-gating system. The initial results prompted us to quantify the pulmonary and vena-cava venous blood flow in addition to arterial hemodynamics. The later study resulted in a novel diagnostic marker - “the pulmonary arteriovenous pressure gradient” - to diagnose pulmonary arterial hypertension non-invasively by MRI. Finally, by refining the sequence and replacing the prospective-gating system with a retrospective k0-navigator and compressed sensing (CS) reconstruction, we could shorten the scan time to almost half the measurement time in the UTE-4D-flow sequence. Finally, we tested the sequence on phantoms and mice, and could confirm the expected advantages which the previous study on rats revealed.

4D Reduced TE (RTE) Spiral Phase Contrast NRI for Rapid Quantification and Visualization of Blood Flow and Hemodynamics

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ISBN 13 :
Total Pages : 158 pages
Book Rating : 4.:/5 (938 download)

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Book Synopsis 4D Reduced TE (RTE) Spiral Phase Contrast NRI for Rapid Quantification and Visualization of Blood Flow and Hemodynamics by : Mohammadjavad Negahdar

Download or read book 4D Reduced TE (RTE) Spiral Phase Contrast NRI for Rapid Quantification and Visualization of Blood Flow and Hemodynamics written by Mohammadjavad Negahdar and published by . This book was released on 2015 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: 4D flow Phase Contrast MRI is a relatively new technique in MRI which is capable of deriving time-resolved three-dimensional velocity fields in a 3D volume noninvasively. 4D flow imaging is a 3D k-space acquisition where for the third dimension, an additional phase-encoding step is required. The velocity field can then be used to obtain flow waveform, wall shear stress, vascular compliance, blood pressure, and other hemodynamic information. A significant limitation of 4D flow methods has been the requisite long scan times, requiring the patient to remain motionless at times on the order of 10-20 minutes, depending on scan parameters. The scan times may become more prohibitive in case of 4D cardiovascular studies where respiratory gating with navigator echoes is required. In this thesis the feasibility of using a reduced TE stack of spirals k-space acquisition for 4D flow imaging are investigated. Starting with fundamentals of MRI, the basics of Phase contrast and 4D flow MRI are thoroughly discussed in Chapter 1-3 and subsequently experimental phantom results are reported in Chapter 4, pointing to the feasibility of performing highly accurate 4D velocity and flow measurement with the proposed pulse sequence under a variety of flow conditions and with substantial reductions in scan time when compared to conventional 4D flow. In phantom studies, results based on the root mean square error criterion indicate that 4D Reduced TE (RTE) Spiral PC MRI is capable of providing the same level of accuracy as conventional 4D conventional PC MRI but in a much shorter scan time (30% reduction in scan time when imaging an FOV of 100*100*60 mm3 and spatial resolution of 1.5*1.5*3 mm3). Moreover, the proposed method has the added advantage of achieving the shorter echo time of 2 ms versus 3.6 ms for conventional 4D flow at Q=50ml/s and 1.57 ms versus 3.2 ms at the higher flow rate of Q=150 ml/s leading to more accurate assessment of flow distal to narrowings. Statistical results indicate that at low flow rates performance of both methods are similar. At higher flow rates, however, 4D RTE spiral flow achieves better accuracy. Qualitative results in phantom studies also revealed that at higher flow rates, better flow visualization was achieved with4D RTE spiral flow compared with conventional 4D flow. In the second part of Chapter 4, we also report on application of the proposed sequence, in-vivo, to 5 healthy volunteers and 5 subjects with mild to moderate Aortic Stenosis (AS) disease. Results from the proposed method were statistically correlated with velocity profiles derived from conventional 4D flow and Doppler Ultrasound. Results indicate that 4D RTE Spiral is capable of providing the same level of accuracy in flow measurement as Conventional 4D flow MRI for imaging of the aortic valve, but on average resulted in a 30% reduction in scan time and 45% reduction in echo time. 4D RTE Spiral was also able to achieve an echo time of 1.68 ms versus 2.9 ms for that of conventional 4D flow MRI, permitting less signal dephasing in the presence of jet flows distal to occlusions. With Doppler Ultrasound adopted as the reference method, 4D RTE Spiral flow measured peak velocity and maximum pressure gradient with a higher level of accuracy when compared to Conventional 4D flow MRI. Both methods measured left-ventricular out flow tract (LVOT) diameter, Aortic Valve (AV) eject time and time to AV peak with same accuracy. It is concluded that 4D RTE Spiral flow MRI is an excellent technique for flow measurement in cardiac patients who are unable to tolerate longer scan times, currently required by conventional 4D flow methods.

Vascular Imaging of the Central Nervous System

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Publisher : John Wiley & Sons
ISBN 13 : 1118188756
Total Pages : 432 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Vascular Imaging of the Central Nervous System by : Joana Ramalho

Download or read book Vascular Imaging of the Central Nervous System written by Joana Ramalho and published by John Wiley & Sons. This book was released on 2014-03-31 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first book-length reference to thoroughly describe diagnostic and therapeutic advances in the development of vascular radiology over the last decade The last ten years has seen vascular imaging of the central nervous system (CNS) evolve from fairly crude, invasive procedures to more advanced imaging methods that are safer, faster, and more precise—with computed tomographic (CT) and magnetic resonance (MR) imaging methods playing a special role in these advances. Vascular Imaging of the Central Nervous System is the first full-length reference text that shows radiologists—especially neuroradiologists—how to optimize the use of the many techniques available in order to increase the sensitivity and specificity of vascular imaging, thereby improving the diagnosis and treatment of individual patients. Each chapter is formatted carefully and divided into two essential parts: The first part describes the physical principles underlying each imaging technique, along potential associated artifacts and pitfalls; the second part addresses clinical applications and novel applications of each method. With a strong focus on the clinical application of each modality or technique in CNS radiology, this book provides in-depth chapter coverage of: • Ultrasound Vascular Imaging (UVI) • Computed Tomography Angiography (CTA) • Magnetic Resonance Vascular imaging (MRV) • Digital subtraction angiography (DSA) • Brain perfusion techniques: CT and MRI • Plaque imaging • Intravascular imaging • Pediatric vascular imaging Along with numerous illustrations and case studies, Vascular Imaging of the Central Nervous System: Physical Principles, Clinical Applications, and Emerging Techniques is an important book for those faced with choosing from the wide range of choices available for clinical practice.

Adult Hydrocephalus

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Publisher : Cambridge University Press
ISBN 13 : 110703177X
Total Pages : 331 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Adult Hydrocephalus by : Daniele Rigamonti

Download or read book Adult Hydrocephalus written by Daniele Rigamonti and published by Cambridge University Press. This book was released on 2014-02-06 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides guidelines for managing this grossly underdiagnosed and undertreated condition, focusing on early detection and timely, effective interventions.

CT and MRI in Congenital Heart Diseases

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Publisher : Springer Nature
ISBN 13 : 9811567557
Total Pages : 584 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis CT and MRI in Congenital Heart Diseases by : Ramiah Rajeshkannan

Download or read book CT and MRI in Congenital Heart Diseases written by Ramiah Rajeshkannan and published by Springer Nature. This book was released on 2020-12-18 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the cross-sectional imaging of congenital heart diseases, and features a wealth of relevant CT and MRI images. Important details concerning anatomy, physiology, embryology and management options are discussed, and the key technical aspects of performing the imaging are explained step by step. Written by a team of respected authors, the book is richly illustrated and supplemented with access to a number of clinical videos. Intended to provide quick and reliable access to high-quality MRI and CT images of frequently encountered congenital and structural heart abnormalities, the book offers a go-to guide for imaging physicians, helping them overcome the steep learning curve for pediatric cardiac imaging.

Cardiac and Vascular Diseases

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ISBN 13 :
Total Pages : 976 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Cardiac and Vascular Diseases by : Hadley L. Conn

Download or read book Cardiac and Vascular Diseases written by Hadley L. Conn and published by . This book was released on 1971 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Improving Assessments of Hemodynamics and Vascular Disease

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Publisher : Linköping University Electronic Press
ISBN 13 : 9176850986
Total Pages : 64 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Improving Assessments of Hemodynamics and Vascular Disease by : Magnus Ziegler

Download or read book Improving Assessments of Hemodynamics and Vascular Disease written by Magnus Ziegler and published by Linköping University Electronic Press. This book was released on 2019-04-24 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood vessels are more than simple pipes, passively enabling blood to pass through them. Their form and function are dynamic, changing with both aging and disease. This process involves a feedback loop wherein changes to the shape of a blood vessel affect the hemodynamics, causing yet more structural adaptation. This feedback loop is driven in part by the hemodynamic forces generated by the blood flow, and the distribution and strength of these forces appear to play a role in the initiation, progression, severity, and the outcome of vascular diseases. Magnetic Resonance Imaging (MRI) offers a unique platform for investigating both the form and function of the vascular system. The form of the vascular system can be examined using MR-based angiography, to generate detailed geometric analyses, or through quantitative techniques for measuring the composition of the vessel wall and atherosclerotic plaques. To complement these analyses, 4D Flow MRI can be used to quantify the functional aspect of the vascular system, by generating a full time-resolved three-dimensional velocity field that represents the blood flow. This thesis aims to develop and evaluate new methods for assessing vascular disease using novel hemodynamic markers generated from 4D Flow MRI and quantitative MRI data towards the larger goal of a more comprehensive non-invasive examination oriented towards vascular disease. In Paper I, we developed and evaluated techniques to quantify flow stasis in abdominal aortic aneurysms to measure this under-explored aspect of aneurysmal hemodynamics. In Paper II, the distribution and intensity of turbulence in the aorta was quantified in both younger and older men to understand how aging changes this aspect of hemodynamics. A method to quantify the stresses generated by turbulence that act on the vessel wall was developed and evaluated using simulated flow data in Paper III, and in Paper V this method was utilized to examine the wall stresses of the carotid artery. The hemodynamics of vascular disease cannot be uncoupled from the anatomical changes the vessel wall undergoes, and therefore Paper IV developed and evaluated a semi-automatic method for quantifying several aspects of vessel wall composition. These developments, taken together, help generate more valuable information from imaging data, and can be pooled together with other methods to form a more comprehensive non-invasive examination for vascular disease.

Chesley's Hypertensive Disorders in Pregnancy

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Publisher : Elsevier
ISBN 13 : 0124079458
Total Pages : 500 pages
Book Rating : 4.1/5 (24 download)

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Book Synopsis Chesley's Hypertensive Disorders in Pregnancy by : Robert N. Taylor

Download or read book Chesley's Hypertensive Disorders in Pregnancy written by Robert N. Taylor and published by Elsevier. This book was released on 2014-08-28 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chesley’s Hypertensive Disorders in Pregnancy continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this the hypertensive disorders remain marginally studied and management is often controversial. The fourth edition of Chesley’s Hypertensive Disorders in Pregnancy focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, and not just preeclampsia. Features new chapters focusing on recent discoveries in areas such as fetal programming, genomics/proteomics, and angiogenesis Includes extensive updates to chapters on epidemiology, etiological considerations, pathophysiology, prediction, prevention, and management Discusses the emerging roles of metabolic syndrome and obesity and the increasing incidence of preeclampsia Each section overseen by one of the editors; each chapter co-authored by one of the editors, ensuring coherence throughout book

Principles and Practice of Cardiac Magnetic Resonance in Congenital Heart Disease

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Publisher : John Wiley & Sons
ISBN 13 : 1444317040
Total Pages : 480 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Principles and Practice of Cardiac Magnetic Resonance in Congenital Heart Disease by : Mark A. Fogel

Download or read book Principles and Practice of Cardiac Magnetic Resonance in Congenital Heart Disease written by Mark A. Fogel and published by John Wiley & Sons. This book was released on 2010-03-02 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: CMR is a powerful tool in the armamentarium of pediatric cardiology and health care workers caring for patients with congenital heart disease (CHD), but a successful study still presents major technical and clinical challenges. This text was created to give trainees, practitioners, allied professionals, and researchers a repository of dependable information and images to base their use of CMR on. Because CHD presents an intricate web of connections and associations that need to be deciphered, the imager performing CMR needs to understand not only anatomy, physiology, function, and surgery for CHD, but also the technical aspects of imaging. Written by experts from the world’s leading institutions, many of whom pioneered the techniques and strategies described, the text is organized in a logical way to provide a complete understanding of the issues involved. It is divided into three main parts: The Basics of CMR - familiarizes the reader with the minimum tools needed to understand the basics, such as evaluating morphology, ventricular function, and utilizing contrast agents CMR of Congenital and Acquired Pediatric Heart Disease - discusses broad categories of CHD and the use of CMR in specific disease states Special Topics in Pediatric Cardiac MR - covers other important areas such as the complementary role of CT scanning, interventional CMR, the role of the technologist in performing a CMR exam, and more With the ever increasing sophistication of technology, more can be done with CMR in a high quality manner in a shorter period of time than had been imagined as recently as just a few years ago. Principles and Practice of Cardiac Magnetic Resonance in Congenital Heart Disease: Form, Function, and Flow makes a major contribution to applying these techniques to improved patient care. An ideal introduction for the novice or just the curious, this reference will be equally useful to the seasoned practitioner who wants to keep pace with developments in the field and would like a repository of information and images readily availalble.

The Mechanics of the Circulation

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Publisher : Cambridge University Press
ISBN 13 : 0521151775
Total Pages : 551 pages
Book Rating : 4.5/5 (211 download)

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Book Synopsis The Mechanics of the Circulation by : C. G. Caro

Download or read book The Mechanics of the Circulation written by C. G. Caro and published by Cambridge University Press. This book was released on 2012 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: This classic book outlines the anatomy and physiology of the circulation and explains the mechanical principles that govern it.

Fascia: The Tensional Network of the Human Body

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Publisher : Elsevier Health Sciences
ISBN 13 : 0702052280
Total Pages : 566 pages
Book Rating : 4.7/5 (2 download)

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Book Synopsis Fascia: The Tensional Network of the Human Body by : Robert Schleip

Download or read book Fascia: The Tensional Network of the Human Body written by Robert Schleip and published by Elsevier Health Sciences. This book was released on 2013-02-26 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the product of an important collaboration between clinicians of the manual therapies and scientists in several disciplines that grew out of the three recent International Fascia Research Congresses (Boston, Amsterdam, and Vancouver). The book editors, Thomas Findley MD PhD, Robert Schleip PhD, Peter Huijing PhD and Leon Chaitow DO, were major organizers of these congresses and used their extensive experience to select chapters and contributors for this book. This volume therefore brings together contributors from diverse backgrounds who share the desire to bridge the gap between theory and practice in our current knowledge of the fascia and goes beyond the 2007, 2009 and 2012 congresses to define the state-of-the-art, from both the clinical and scientific perspective. Prepared by over 100 specialists and researchers from throughout the world, Fascia: The Tensional Network of the Human Body will be ideal for all professionals who have an interest in fascia and human movement - physiotherapists, osteopathic physicians, osteopaths, chiropractors, structural integration practitioners, manual therapists, massage therapists, acupuncturists, yoga or Pilates instructors, exercise scientists and personal trainers - as well as physicians involved with musculoskeletal medicine, pain management and rehabilitation, and basic scientists working in the field. Reflects the efforts of almost 100 scientists and clinicians from throughout the world Offers comprehensive coverage ranging from anatomy and physiology, clinical conditions and associated therapies, to recently developed research techniques Explores the role of fascia as a bodywide communication system Presents the latest information available on myofascial force transmission which helps establish a scientific basis for given clinical experiences Explores the importance of fascia as a sensory organ - for example, its important proprioceptive and nociceptive functions which have implications for the generation of low back pain Describes new imaging methods which confirm the connectivity of organs and tissues Designed to organize relevant information for professionals involved in the therapeutic manipulation of the body’s connective tissue matrix (fascia) as well as for scientists involved in basic science research Reflects the increasing need for information about the properties of fascia, particularly for osteopaths, massage therapists, physiotherapists and other complementary health care professionals Offers new insights on the fascial related foundations of Traditional Chinese Medicine Meridians and the fascial effects of acupuncture

Aortic Dissection and Related Syndromes

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Publisher : Springer Science & Business Media
ISBN 13 : 0387360018
Total Pages : 363 pages
Book Rating : 4.3/5 (873 download)

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Book Synopsis Aortic Dissection and Related Syndromes by : Ragavendra Baliga

Download or read book Aortic Dissection and Related Syndromes written by Ragavendra Baliga and published by Springer Science & Business Media. This book was released on 2007-04-03 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: This state-of the-art publication is a result of the combined efforts of participants from the International Registry of Aortic Dissection (IRAD). It is the most comprehensive reference on aortic dissection The book has been divided into sections. Each chapter provides a succinct overview of the current clinical literature and incorporates illustrations for further explanation.

Towards Personalized Models of the Cardiovascular System Using 4D Flow MRI

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Publisher : Linköping University Electronic Press
ISBN 13 : 9176852172
Total Pages : 71 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Towards Personalized Models of the Cardiovascular System Using 4D Flow MRI by : Belén Casas Garcia

Download or read book Towards Personalized Models of the Cardiovascular System Using 4D Flow MRI written by Belén Casas Garcia and published by Linköping University Electronic Press. This book was released on 2019-02-15 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current diagnostic tools for assessing cardiovascular disease mostly focus on measuring a given biomarker at a specific spatial location where an abnormality is suspected. However, as a result of the dynamic and complex nature of the cardiovascular system, the analysis of isolated biomarkers is generally not sufficient to characterize the pathological mechanisms behind a disease. Model-based approaches that integrate the mechanisms through which different components interact, and present possibilities for system-level analyses, give us a better picture of a patient’s overall health status. One of the main goals of cardiovascular modelling is the development of personalized models based on clinical measurements. Recent years have seen remarkable advances in medical imaging and the use of personalized models is slowly becoming a reality. Modern imaging techniques can provide an unprecedented amount of anatomical and functional information about the heart and vessels. In this context, three-dimensional, three-directional, cine phase-contrast (PC) magnetic resonance imaging (MRI), commonly referred to as 4D Flow MRI, arises as a powerful tool for creating personalized models. 4D Flow MRI enables the measurement of time-resolved velocity information with volumetric coverage. Besides providing a rich dataset within a single acquisition, the technique permits retrospective analysis of the data at any location within the acquired volume. This thesis focuses on improving subject-specific assessment of cardiovascular function through model-based analysis of 4D Flow MRI data. By using computational models, we aimed to provide mechanistic explanations of the underlying physiological processes, derive novel or improved hemodynamic markers, and estimate quantities that typically require invasive measurements. Paper I presents an evaluation of current markers of stenosis severity using advanced models to simulate flow through a stenosis. Paper II presents a framework to personalize a reduced-order, mechanistic model of the cardiovascular system using exclusively non-invasive measurements, including 4D Flow MRI data. The modelling approach can unravel a number of clinically relevant parameters from the input data, including those representing the contraction and relaxation patterns of the left ventricle, and provide estimations of the pressure-volume loop. In Paper III, this framework is applied to study cardiovascular function at rest and during stress conditions, and the capability of the model to infer load-independent measures of heart function based on the imaging data is demonstrated. Paper IV focuses on evaluating the reliability of the model parameters as a step towards translation of the model to the clinic.

Automated Assessment of Blood Flow in the Cardiovascular System Using 4D Flow MRI

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Publisher : Linköping University Electronic Press
ISBN 13 : 9176853462
Total Pages : 77 pages
Book Rating : 4.1/5 (768 download)

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Book Synopsis Automated Assessment of Blood Flow in the Cardiovascular System Using 4D Flow MRI by : Mariana Bustamante

Download or read book Automated Assessment of Blood Flow in the Cardiovascular System Using 4D Flow MRI written by Mariana Bustamante and published by Linköping University Electronic Press. This book was released on 2018-03-23 with total page 77 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical image analysis focuses on the extraction of meaningful information from medical images in order to facilitate clinical assessment, diagnostics and treatment. Image processing techniques have gradually become an essential part of the modern health care system, a consequence of the continuous technological improvements and the availability of a variety of medical imaging techniques. Magnetic Resonance Imaging (MRI) is an imaging technique that stands out as non-invasive, highly versatile, and capable of generating high quality images without the use of ionizing radiation. MRI is frequently performed in the clinical setting to assess the morphology and function of the heart and vessels. When focusing on the cardiovascular system, blood flow visualization and quantification is essential in order to fully understand and identify related pathologies. Among the variety of MR techniques available for cardiac imaging, 4D Flow MRI allows for full three-dimensional spatial coverage over time, also including three-directional velocity information. It is a very powerful technique that can be used for retrospective analysis of blood flow dynamics at any location in the acquired volume. In the clinical routine, however, flow analysis is typically done using two-dimensional imaging methods. This can be explained by their shorter acquisition times, higher in-plane spatial resolution and signal-to-noise ratio, and their relatively simpler post-processing requirements when compared to 4D Flow MRI. The extraction of useful knowledge from 4D Flow MR data is especially challenging due to the large amount of information included in these images, and typically requires substantial user interaction. This thesis aims to develop and evaluate techniques that facilitate the post-processing of thoracic 4D Flow MRI by automating the steps necessary to obtain hemodynamic parameters of interest from the data. The proposed methods require little to no user interaction, are fairly quick, make effective use of the information available in the four-dimensional images, and can easily be applied to sizable groups of data.The addition of the proposed techniques to the current pipeline of 4D Flow MRI analysis simplifies and expedites the assessment of these images, thus bringing them closer to the clinical routine. Medicinsk bildanalys fokuserar på extrahering av meningsfull information från medicinska bilder för att underlätta klinisk bedömning, diagnostik, och behandling. Bildbehandlingsteknik har gradvis blivit en viktig del av det moderna sjukvårdsystemet, en följd av de kontinuerliga tekniska förbättringarna och tillgången till en mängd olika medicinska bildtekniker. Magnetic resonanstomografi (MRT) är en bildteknik som är ickeinvasiv, flexibel och kan generera bilder av hög kvalitet utan joniserande strålning. MRT utförs ofta i klinisk miljö för att bedöma anatomi och funktion av hjärtat och blodkärlen. När man fokuserar på hjärt-kärlsystemet är bedömning av blodflödet viktigt för att kunna förstå och identifiera sjukdomar fullt ut. Bland de olika MRT-teknikerna som är tillgängliga för avbildning av hjärtat möjliggör 4D flödes-MRT komplett täckning av hjärtat i tre dimensioner över tid, och med hastighetsinformation i tre riktningar. 4D flödes-MRT är en mycket effektiv metod som kan användas för retrospektiv analys av blodflödesdynamik på vilken position som helst i den avbildade volymen. Till vardags görs dock blodflödesanalysen vanligtvis på bilder tagna med tvådimensionella avbildningsmetoder. Detta kan förklaras av deras kortare insamlingstider, högre spatiella upplösning, bättre signal-brusförhållandet, och att de är relativt enklare att efterbehandla jämfört med 4D flödes-MRT. Utvinningen av användbar information från 4D flödes-MRT-data är väldigt utmanande på grund av den stora mängden information som dessa bilder innehåller och kräver vanligtvis väsentlig användarinteraktion. Denna avhandling syftar till att utveckla och utvärdera metoder som underlättar efterbehandlingen av 4D flödes-MRT genom att automatisera de steg som är nödvändiga för att härleda hemodynamiska parametrarna av intresse från dessa data. De föreslagna metoderna kräver liten eller ingen användarinteraktion, är relativt snabba, använder all information som finns i de fyrdimensionella bilderna, och kan enkelt appliceras på stora datamängder. Tillägget av de i avhandlingen beskrivna metoderna till den nuvarande analysen av 4D flödes-MRT medger en avsevärd förenkling och uppsnabbad utvärdering, vilket gör att den avancerade 4D flödes MRT-tekniken kommer närmare att kunna användas i kliniskt rutinarbete.

Ultrafast Ultrasound Imaging

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Publisher : MDPI
ISBN 13 : 3038971278
Total Pages : 185 pages
Book Rating : 4.0/5 (389 download)

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Book Synopsis Ultrafast Ultrasound Imaging by : Hideyuki Hasegawa

Download or read book Ultrafast Ultrasound Imaging written by Hideyuki Hasegawa and published by MDPI. This book was released on 2018-09-21 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue "Ultrafast Ultrasound Imaging" that was published in Applied Sciences

Snapshots of Hemodynamics

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Publisher : Springer Science & Business Media
ISBN 13 : 0387233466
Total Pages : 182 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Snapshots of Hemodynamics by : Nico Westerhof

Download or read book Snapshots of Hemodynamics written by Nico Westerhof and published by Springer Science & Business Media. This book was released on 2006-01-12 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemodynamics makes it possible to characterize in a quantitative way, the function of the heart and arterial system, thereby producing information about what genetic and molecular processes are of importance for cardiovascular function. Snapshots of Hemodynamics: An Aid for Clinical Research and Graduate Education by Nico Westerhof, Nikos Stergiopulos and Mark I. M. Noble is a quick reference guide designed to help basic and clinical researchers as well as graduate students to understand hemodynamics. The layout of the book provides short and independent chapters that provide teaching diagrams as well as clear descriptions of the essentials of basic and applied principles of hemodynamics. References are provided at the end of each chapter for further reading and reference.

The EACVI Textbook of Cardiovascular Magnetic Resonance

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Publisher : Oxford University Press
ISBN 13 : 0191085057
Total Pages : 673 pages
Book Rating : 4.1/5 (91 download)

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Book Synopsis The EACVI Textbook of Cardiovascular Magnetic Resonance by : Victor Ferrari

Download or read book The EACVI Textbook of Cardiovascular Magnetic Resonance written by Victor Ferrari and published by Oxford University Press. This book was released on 2018-09-13 with total page 673 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly comprehensive and informed textbook has been prepared by the Cardiovascular Magnetic Resonance section of the European Society of Cardiology association on imaging, the EACVI. The EACVI Textbook of Cardiovascular Magnetic Resonance is the authority on the subject. The textbook is aligned with ESC Core Curriculum and EACVI Core Syllabus for CMR. It is a practical resource and provides a disease orientated outlook on the subject. Structured with thirteen clear and detailed sections, ranging from Physics to Methodology, and featuring specific sections on ischemic heart disease, myocardial disease, pericardial disease, and congenital heart disease and adult congenital heart disease, The EACVI Textbook of Cardiovascular Magnetic Resonance provides extensive knowledge across the entire subject area in CMR. Beautifully illustrated and physical principles enriched with schematic animations, the textbook is advanced further with key video content based on clinical cases. Written by leading experts in the field from across the world, the textbook aims to summarise the existing research and clinical evidence for the various CMR indications and provide an invaluable resource for cardiologists and radiologists across the board. The textbook is ideal for cardiologists and radiologists new to the field of Cardiovascular Magnetic Resonance, those preparing for ESC certification in CMR, and those established in the field wishing to gain a deep understanding of CMR. Online access to the digital version is included with purchase of the print book, with accompanying videos referenced within the text available on Oxford Medicine Online.