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Nih State Of The Science Conference Statement On Role Of Active Surveillance In The Management Of Men With Localized Prostate Cancer
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Book Synopsis NIH State-of-the-Science Conference Statement on Role of Active Surveillance in the Management of Men with Localized Prostate Cancer by :
Download or read book NIH State-of-the-Science Conference Statement on Role of Active Surveillance in the Management of Men with Localized Prostate Cancer written by and published by . This book was released on 2011 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :U. S. Department of Health and Human Services Publisher :CreateSpace ISBN 13 :9781484054628 Total Pages :344 pages Book Rating :4.0/5 (546 download)
Book Synopsis An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer by : U. S. Department of Health and Human Services
Download or read book An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer written by U. S. Department of Health and Human Services and published by CreateSpace. This book was released on 2013-04-06 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2011, more than 240,000 men are projected to be diagnosed with prostate cancer, and 33,000 are projected to die from the disease in the United States. In the United States, most cases of prostate cancer are detected via prostate-specific antigen (PSA) screening. The cancer is usually localized, and most tumors have low histological grades and low Gleason scores. Indeed, more than half of prostate cancers detected by PSA screening are expected to be early-stage, low-risk tumors. Such cancers are an infrequent cause of death, and those affected are more likely to die of unrelated causes. A number of immediate active treatment options are available for localized prostate cancer. Most commonly, radical prostatectomy (RP) or radiation therapy (RT), with or without androgen deprivation therapy (ADT), are offered with curative intent. However, the clinical benefit of immediate therapy with curative intent has not yet been demonstrated for localized prostate cancer in a PSA-screened population. It is likely that a large number of men are receiving active treatment with curative intent without much likelihood of obtaining any clinical benefit due to the slow progression of many prostate tumors. Both surgical and radiation treatments result in significant short- and long-term adverse events, including impotence, urinary dysfunction, and other complications. Thus, determination of the appropriate management strategy for early-stage, low-risk prostate cancer is an important public health concern. Active surveillance (AS) and watchful waiting (WW) are two observational followup strategies that forgo immediate therapy in patients with prostate cancer, with the goal of minimizing the morbidities and costs of immediate active treatment for men who may never develop cancer-related symptoms or who are interested in palliative treatments only. AS is curative in intent, and WW is palliative. AS is appropriate in men with disease believed to be indolent and therefore may not require therapy. Because prediction tools are imperfect, these men are monitored closely and treated with curative intent at signs of progression or patient choice. In this way, the considerable adverse effects of treatment are at best avoided, and at least deferred. This approach is to be distinguished from men for whom treatment is deemed inappropriate because of comorbidity; for these men, WW is generally considered, as it offers the option of palliative therapy upon symptomatic disease progression. AS often entails a multifactorial followup of patients—monitoring of PSA values, digital rectal examinations (DRE), prostate imaging, and periodic prostate biopsies—while WW is commonly a relatively passive strategy—with interventions triggered by symptoms. However, there is a continuum of aggressiveness of followup for both AS and WW, as practiced in the community. The objective of this report is to summarize the existing literature regarding the role of AS in the management of early-stage, low-risk prostate cancer. Both the report and the corresponding NIH State-of-the-Science conference are a part of the NIH Consensus Development Program, the purpose of which is to evaluate the scientific evidence on a particular topic and develop a consensus statement that advances research in that area. Key Questions provided to the EPC for systematic review include: 1. How have the patient population and the natural history of prostate cancer diagnosed in the United States changed in the last 30 years? 2. How are active surveillance and other observational management strategies defined? 3. What factors affect the offer of, acceptance, and adherence to active surveillance? 4. What are the comparative short- and long-term outcomes of active surveillance versus immediate treatment with curative intent for localized prostate cancer? 5. What are the research needs regarding active surveillance (or watchful waiting) in localized prostate cancer?
Book Synopsis Role of Active Surveillance in the Management of Localized Prostate Cancer by : National Cancer Institute (U.S.)
Download or read book Role of Active Surveillance in the Management of Localized Prostate Cancer written by National Cancer Institute (U.S.) and published by . This book was released on 2011 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Active Surveillance for Localized Prostate Cancer by : Laurence Klotz
Download or read book Active Surveillance for Localized Prostate Cancer written by Laurence Klotz and published by Springer Science & Business Media. This book was released on 2012-06-21 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Active Surveillance for Localized Prostate Cancer: A New Paradigm for Clinical Management will serve as a useful resource for physicians dealing with, and interested in, this complex and evolving branch of prostate cancer management. The book will also be of interest to scientifically literate patients and their families. The volume provides an introduction to the concept of active surveillance in oncology in general and prostate cancer specifically. The primary focus is to provide a comprehensive guide to the management of patients on surveillance. The volume covers the many complexities and nuances to this approach including, patient selection, risk assessment, how to overcome 'cancer hysteria' when counseling patients, identifying appropriate triggers for intervention, use of PSA kinetics and MR imaging information, technique and frequency of biopsies, secondary prevention interventions, and the relative roles of surveillance and focal therapy.
Book Synopsis Journal of the National Cancer Institute by :
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 1990 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Active Surveillance for Localized Prostate Cancer by : Laurence Klotz
Download or read book Active Surveillance for Localized Prostate Cancer written by Laurence Klotz and published by Humana Press. This book was released on 2017-09-29 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the role of biomarkers and MRI in patient selection and management and details the world wide results of active surveillance. Specific chapters address communication and ethical issues, QOL outcomes, economic aspects, and psycho-social aspects of surveillance. The role of focal therapy for low risk disease is summarized, and the data supporting preventive interventions during surveillance reviewed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in this common malignancy, as it provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.
Book Synopsis An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer by :
Download or read book An Evidence Review of Active Surveillance in Men with Localized Prostate Cancer written by and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: BACKGROUND: Radical prostatectomy and radiation therapy for prostate cancer have side effects and unclear survival benefits for early stage and low-risk disease. Prostate cancer often has an indolent natural history, making observational management strategies potentially appealing. PURPOSE: To systematically review the role of active surveillance for triggers to begin curative treatment in men with low-risk prostate cancer. Key Questions address changes in prostate cancer characteristics over time, definitions of active surveillance and other observational strategies, factors affecting the offer of, acceptance of, and adherence to active surveillance, the comparative effectiveness of active surveillance with curative treatments, and research gaps. DATA SOURCES: MEDLINE(r), Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and existing systematic reviews, evidence reports, and economic evaluations. STUDY SELECTION: Randomized controlled trials and nonrandomized comparative studies of treatments, multivariable association studies, and studies of temporal trends in prostate cancer natural history. Only published, peer-reviewed, English-language articles were selected based on predetermined eligibility criteria. DATA EXTRACTION: A standardized protocol was used to extract details on design, diagnoses, interventions, predictive factors, outcomes, and study validity. DATA SYNTHESIS: In total, 80 studies provided information on epidemiologic trends; 56 on definitions of active surveillance; 42 on factors affecting the offer of, acceptance of, or adherence to observational management strategies; and 26 on comparative effectiveness. Increased diagnosis of early-stage prostate cancer due to prostate-specific antigen (PSA) testing, led to an increase in prostate cancer incidence from the mid-1980s to the mid-1990s. The prostate cancer-specific mortality rate decreased for all age groups from the early-1990s to 1999. Currently, patients are diagnosed with earlier stage and lower risk prostate cancers compared to the pre-PSA era. Over time, a lower proportion of men received observational management versus active treatment, even among those with low-risk disease. There was no standardized definition of active surveillance. Sixteen cohorts used different monitoring protocols, all with different combinations of periodic digital rectal examination, PSA testing, rebiopsy, and/or imaging findings. Predictors that a patient received no initial active treatment generally included older age, presence of comorbidities, lower Gleason score, lower tumor stage, lower diagnostic PSA, and lower disease progression risk group. No trial provided results comparing men with localized disease on active surveillance with surgery or radiation therapy. LIMITATIONS: Because of the nonstandardized usages of the terms "active surveillance" and "watchful waiting" and their intended and often mixed (both curative and palliative) treatment objectives, it was difficult to determine which study patients received active monitoring for triggers indicative of curative treatment and which observation for clinical symptoms indicative of palliative treatment. CONCLUSIONS: More men are being diagnosed with early stage prostate cancer. Whether active monitoring with a curative intent is an appropriate option for these men remains unclear. A standard, universally agreed-upon definition of active surveillance that clearly distinguishes it from watchful waiting and other observational management strategies is needed to help clarify scientific discourse on this topic. Ongoing clinical trials may provide information on the comparative effectiveness of active surveillance compared to immediate active treatment, but will require long term followup.
Book Synopsis Cancer Prevention and Screening by : Rosalind A. Eeles
Download or read book Cancer Prevention and Screening written by Rosalind A. Eeles and published by John Wiley & Sons. This book was released on 2018-08-15 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer Prevention and Screening offers physicians and all clinical healthcare professionals a comprehensive, useful source of the latest information on cancer screening and prevention with both a global and a multidisciplinary perspective. Includes background information on epidemiology, cancer prevention, and cancer screening, for quick reference Offers the latest information for clinical application of the most recent techniques in prevention and screening of all major and many lesser cancer types Emphasises the importance of multidisciplinary teamwork in cancer screening Highlights frequent dilemmas and difficulties encountered during cancer screening Provides clear-cut clinical strategies for optimal patient education, communication, and compliance with cancer prevention techniques
Book Synopsis Oxford Textbook of Urological Surgery by : Freddie C. Hamdy
Download or read book Oxford Textbook of Urological Surgery written by Freddie C. Hamdy and published by Oxford University Press. This book was released on 2017-10-20 with total page 3091 pages. Available in PDF, EPUB and Kindle. Book excerpt: Offering a comprehensive guide, the Oxford Textbook of Urological Surgery is a practical resource mapped to the curriculum for urological training as approved by the General Medical Council (GMC), making it particularly useful in preparation for the Intercollegiate Examination. Presented in a clear and accessible way, this evidence based volume covers all major areas, including functional urology, stone disease, infection, andrology, nephrology, transplantation, uroradiology, and paediatric urology. This highly illustrated full colour textbook has an innovative and user-friendly style, including over 500 photographs, clinical images, and line drawings. Bringing together the expertise of over 100 specialist contributors in the field, the Oxford Textbook of Urological Surgery is a highly valuable source of information, and will become the standard reference text for all who study urological disease and its treatment.
Book Synopsis Ferri's Clinical Advisor 2017 E-Book by : Fred F. Ferri
Download or read book Ferri's Clinical Advisor 2017 E-Book written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2016-05-27 with total page 7076 pages. Available in PDF, EPUB and Kindle. Book excerpt: Access up-to-date diagnostic and treatment information on more than 700 common medical conditions with Ferri’s Clinical Advisor 2017, which boasts the popular "5 books in 1" format! Published annually and now in its 19th year, it provides quick guidance on diseases and disorders, differential diagnoses, medical algorithms, laboratory tests, and clinical practice guidelines, while additional electronic content equips you with e-only topics, images, tables, and much more. Updated content by experts in key clinical fields helps you keep pace with the speed of modern medicine. Popular "5 books in 1" format includes cross-references, outlines, bullets, tables, boxes, and algorithms to help expedite search. Diseases and Disorders section features more than 300 new figures and tables, as well as 20 new topics including: cyclic vomiting syndrome, traveler’s diarrhea, chronic pruritus, post-herpetic neuralgia, enteropathic arthritis, and hoarding disorder. Differential Diagnosis section highlights 50 new topics, including: alcohol-related seizures, dysentery and inflammatory enterocolitis, hair loss, cystic and solid pancreatic lesions, and COPD decompensation. New algorithms offer important diagnostic information on 19 added conditions, including allergic reaction to vaccines, cardiac arrest, occupational asthma, urinary tract infection, and vertigo and dizziness. Current ICD-10 insurance billing codes help expedite insurance reimbursements.
Book Synopsis Ferri's Clinical Advisor 2021 by : Fred F. Ferri
Download or read book Ferri's Clinical Advisor 2021 written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2020-06-10 with total page 4158 pages. Available in PDF, EPUB and Kindle. Book excerpt: Find fast answers to inform your daily diagnosis and treatment decisions! Ferri’s Clinical Advisor 2021 uses the popular "5 books in 1" format to deliver vast amounts of information in a clinically relevant, user-friendly manner. This bestselling reference has been significantly updated to provide you with easy access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, clinical algorithms, laboratory tests, and clinical practice guidelines—all carefully reviewed by experts in key clinical fields. Extensive algorithms, along with hundreds of new figures and tables, ensure that you stay current with today's medical practice. Contains significant updates throughout, covering all aspects of current diagnosis and treatment. Features 27 all-new topics including chronic rhinosinusitis, subclinical brain infarction, reflux-cough syndrome, radiation pneumonitis, catatonia, end-stage renal disease, and genitourinary syndrome of menopause, among others. Includes new appendices covering common herbs in integrated medicine and herbal activities against pain and chronic diseases; palliative care; and preoperative evaluation. Offers online access to Patient Teaching Guides in both English and Spanish.
Book Synopsis The Handbook of Health Behavior Change by : Marisa E. Hilliard, PhD
Download or read book The Handbook of Health Behavior Change written by Marisa E. Hilliard, PhD and published by Springer Publishing Company. This book was released on 2018-04-28 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised and updated fifth edition of the highly acclaimed “gold standard” textbook continues to provide a foundational review of health behavior change theories, research methodologies, and intervention strategies across a range of populations, age groups, and health conditions. It examines numerous, complex, and often co-occurring factors that can both positively and negatively influence people’s ability to change behaviors to enhance their health including intrapersonal, interpersonal, sociocultural, environmental, systems, and policy factors, in the context of leading theoretical frameworks. Beyond understanding predictors and barriers to achieving meaningful health behavior change, the Handbook provides an updated review of the evidence base for novel and well-supported behavioral interventions and offers recommendations for future research. New content includes chapters on Sun Protection, Interventions With the Family System, and the Role of Technology in Behavior Change. Throughout the textbook, updated reviews emphasize mobile health technologies and electronic health data capture and transmission and a focus on implementation science. And the fifth edition, like the previous edition, provides learning objectives to facilitate use by course instructors in health psychology, behavioral medicine, and public health. The Handbook of Health Behavior Change, Fifth Edition, is a valuable resource for students at the graduate and advanced undergraduate level in the fields of public or population health, medicine, behavioral science, health communications, medical sociology and anthropology, preventive medicine, and health psychology. It also is a great reference for clinical investigators, behavioral and social scientists, and healthcare practitioners who grapple with the challenges of supporting individuals, families, and systems when trying to make impactful health behavior change. NEW TO THE FIFTH EDITION: Revised and updated to encompass the most current research and empirical evidence in health behavior change Includes new chapters on Sun Protection, Interventions With the Family System, and the Role of Technology in Behavior Change Increased focus on innovations in technology in relation to health behavior change research and interventions KEY FEATURES: The most comprehensive review of behavior change interventions Provides practical, empirically based information and tools for behavior change Focuses on robust behavior theories, multiple contexts of health behaviors, and the role of technology in health behavior change Applicable to a wide variety of courses including public health, behavior change, preventive medicine, and health psychology Organized to facilitate curriculum development and includes tools to assist course instructors, including learning objectives for each chapter
Download or read book Prostate Cancer written by Jack H. Mydlo and published by Academic Press. This book was released on 2015-09-29 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility, cancer metastases, prostate physiology, proteomics, new therapeutics, and clinical trials. Presents a comprehensive, translational source for all aspects of prostate cancer in one reference work Provides a common language for cancer researchers, oncologists, and urologists to discuss prostate tumors and how prostate cancer metastases affects other major organ systems Offers insights to research clinicians, giving them a key understanding the molecular basis of prostate cancer Offers insights to cancer researchers into how clinical observations and practices can feed back into the research cycle and, therefore, can contribute to the development of more targeted genomic and proteomic assays
Book Synopsis Ferri's Clinical Advisor 2020 E-Book by : Fred F. Ferri
Download or read book Ferri's Clinical Advisor 2020 E-Book written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2019-06-01 with total page 2136 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significantly updated with the latest developments in diagnosis and treatment recommendations, Ferri’s Clinical Advisor 2020 features the popular "5 books in 1" format to organize vast amounts of information in a clinically relevant, user-friendly manner. This efficient, intuitive format provides quick access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, and laboratory tests – all reviewed by experts in key clinical fields. Updated algorithms, along with hundreds of new figures, tables, and boxes, ensure that you stay current with today’s medical practice. Contains significant updates throughout, covering all aspects of current diagnosis and treatment. Features 27 all-new topics including chronic traumatic encephalopathy, medical marijuana, acute respiratory failure, gallbladder carcinoma, shift work disorder, radial tunnel syndrome, fertility preservation in women, fallopian tube cancer, primary chest wall cancer, large-bowel obstruction, inguinal hernia, and bundle branch block, among others. Includes a new appendix covering Physician Quality Reporting System (PQRS) Measures. Provides current ICD-10 insurance billing codes to help expedite insurance reimbursements. Patient Teaching Guides for many of the diseases and disorders are included, most available in both English and Spanish versions, which can be downloaded and printed for patients.
Book Synopsis Ferri's Clinical Advisor 2019 E-Book by : Fred F. Ferri
Download or read book Ferri's Clinical Advisor 2019 E-Book written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2018-05-26 with total page 7409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated annually with the latest developments in diagnosis and treatment recommendations, Ferri’s Clinical Advisor uses the popular "5 books in 1" format to organize vast amounts of information in a clinically relevant, user-friendly manner. This efficient, intuitive format provides quick access to answers on more than 900 common medical conditions, including diseases and disorders, differential diagnoses, and laboratory tests – all updated by experts in key clinical fields. Updated algorithms and current clinical practice guidelines help you keep pace with the speed of modern medicine. Contains significant updates throughout, with more than 500 new figures, tables, and boxes added to this new edition. Features 17 all-new topics including opioid overdose, obesity-Hypoventilation syndrome, acute pelvic pain in women, new-onset seizures, and eosinophilic esophagitis, among many others. Provides current ICD-10 insurance billing codes to help expedite insurance reimbursements. Includes cross-references, outlines, bullets, tables, boxes, and algorithms to help you navigate a wealth of clinical information. Offers access to exclusive online content: more than 90 additional topics; new algorithms, images, and tables; EBM boxes; patient teaching guides, color images, and more.
Book Synopsis Genitourinary Pathology, An Issue of Surgical Pathology Clinics by : Michelle S. Hirsch
Download or read book Genitourinary Pathology, An Issue of Surgical Pathology Clinics written by Michelle S. Hirsch and published by Elsevier Health Sciences. This book was released on 2016-01-14 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Surgical Pathology Clinics focuses on diseases of the genitourinary tract: Prostate, Kidney, Bladder, Testes, and Adrenals. As with all information in this series, presentations relate to the daily practice of surgical pathologists. A practical and innovative feature in this issue is the inclusion of several articles from the "clinician's perspective” in which an oncologist discusses the diagnosis of the disease and relates this to the information they require from the pathologist. Topics include: Morphologic updates in prostate pathology; Molecular updates in prostate pathology; Diagnosis of prostate carcinoma: A clinician's perspective; Commonly encountered renal neoplasms; Emerging entities in renal neoplasia; Diagnosis of renal cell carcinoma: A clinician's perspective; Morphologic and molecular characteristics of bladder cancer; Diagnosis of bladder carcinoma: A clinician's perspective; Overview of testicular neoplasia; Diagnosis of testicular cancer: A clinician's perspective; Overview of adrenal neoplasia; Diagnosis of adrenal carcinoma: A clinician's perspective; Benign lesions of the GU tract . Michelle Hirsch leads this issue with a group of expert genitourinary pathologists and oncologists.
Book Synopsis Ferri's Clinical Advisor 2016 E-Book by : Fred F. Ferri
Download or read book Ferri's Clinical Advisor 2016 E-Book written by Fred F. Ferri and published by Elsevier Health Sciences. This book was released on 2015-05-28 with total page 5308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ferri’s Clinical Advisor 2016 is simply the fastest, most effective way to access up-to-date diagnostic and treatment information on more than 700 common medical conditions. The popular "5 books in 1" format provides quick guidance on diseases and disorders, differential diagnoses, medical algorithms, laboratory tests, and clinical practice guidelines. An easy-to-use format with cross-references, outlines, bullets, tables, boxes, and algorithms to expedite your search More than 200 lab tests help hone your skills in reviewing normal values and interpreting results Electronic access to additional algorithms, new images and tables, EBM boxes, patient teaching guides, and extra topics. Links between each section allow you to navigate easily from a selected topic to relevant associated material and back again
