New Frontiers In Gene Modified T Cell Technology

Download New Frontiers In Gene Modified T Cell Technology full books in PDF, epub, and Kindle. Read online New Frontiers In Gene Modified T Cell Technology ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

New Frontiers in Gene-Modified T Cell Technology

Author : Ignazio Caruana
Publisher : Frontiers Media SA
ISBN 13 : 283255041X
Total Pages : 222 pages
Book Rating : 4.8/5 (325 download)

DOWNLOAD NOW!

Book Synopsis New Frontiers in Gene-Modified T Cell Technology by : Ignazio Caruana

Download or read book New Frontiers in Gene-Modified T Cell Technology written by Ignazio Caruana and published by Frontiers Media SA. This book was released on 2024-06-13 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development, clinical translation and recent efficacy of novel gene therapies targeting refractory malignancies has led to research that extends this technology to a variety of infectious and rheumatological diseases. Unlike conventional drugs or antibodies, T cells have the potential to target and exert effector function in response to disease in a dynamic manner, acting as a “living drug”. The most efficacious form of gene-modified T cells to date is the chimeric antigen receptor (CAR)-modified T cell, which redirects the specificity of T cells to an antigen expressed by tumor cells. Clinical experience with autologous CAR-T cells, primarily in hematologic malignancies, has underscored the feasibility and safety of the approach, while also demonstrating dramatic and sustained antitumor effects through mechanisms orthogonal to those of traditional anticancer therapies. However, several challenging obstacles must be surmounted in order to improve the broader efficacy of this approach.

New Frontiers of Multidisciplinary Research in STEAM-H (Science, Technology, Engineering, Agriculture, Mathematics, and Health)

Author : Bourama Toni
Publisher : Springer
ISBN 13 : 3319077554
Total Pages : 389 pages
Book Rating : 4.3/5 (19 download)

DOWNLOAD NOW!

Book Synopsis New Frontiers of Multidisciplinary Research in STEAM-H (Science, Technology, Engineering, Agriculture, Mathematics, and Health) by : Bourama Toni

Download or read book New Frontiers of Multidisciplinary Research in STEAM-H (Science, Technology, Engineering, Agriculture, Mathematics, and Health) written by Bourama Toni and published by Springer. This book was released on 2014-09-25 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly multidisciplinary volume contains contributions from leading researchers in STEAM-H disciplines (Science, Technology, Engineering, Agriculture, Mathematics and Health). The volume explores new frontiers in multidisciplinary research, including: the mathematics of cardiac arrhythmia; brain research on working memory; penalized ordinal regression to classify melanoma skin samples; forecasting of time series data; dynamics of niche models; analysis of chemical moieties as anticancer agents; study of gene locus control regions; qualitative mathematical modelling; convex quadrics and group circle systems; remanufacturing planning and control; complexity reduction of functional differential equations; computation of viscous interfacial motion; and differentiation in human pluripotent stem cells. An extension of a seminar series at Virginia State University, the collection is intended to foster student interest and participation in interdisciplinary research and to stimulate new research. The content will be of interest to a broad spectrum of scientists, mathematicians and research students working in interdisciplinary fields including the biosciences, mathematics, engineering, neurosciences and behavioral sciences.

The Heterogeneity of Cancer Metabolism

Author : Anne Le
Publisher : Springer
ISBN 13 : 331977736X
Total Pages : 186 pages
Book Rating : 4.3/5 (197 download)

DOWNLOAD NOW!

Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le

Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Redesigning Life

Author : John Parrington
Publisher : Oxford University Press
ISBN 13 : 0198766823
Total Pages : 371 pages
Book Rating : 4.1/5 (987 download)

DOWNLOAD NOW!

Book Synopsis Redesigning Life by : John Parrington

Download or read book Redesigning Life written by John Parrington and published by Oxford University Press. This book was released on 2016 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid developments in the manipulation of genomes, including editing genes with 'molecular scissors' and the synthesizing of new lifeforms look set to transform our future, and perhaps that of life on Earth. John Parrington explains the cutting edge science and its implications.

Regulatory Aspects of Gene Therapy and Cell Therapy Products

Author : Maria Cristina Galli
Publisher : Springer Nature
ISBN 13 : 3031345673
Total Pages : 243 pages
Book Rating : 4.0/5 (313 download)

DOWNLOAD NOW!

Book Synopsis Regulatory Aspects of Gene Therapy and Cell Therapy Products by : Maria Cristina Galli

Download or read book Regulatory Aspects of Gene Therapy and Cell Therapy Products written by Maria Cristina Galli and published by Springer Nature. This book was released on 2023-08-01 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the different regulatory pathways for Advanced Therapy Medicinal Products implemented by national agencies in North and South America, Europe and Asia and by international bodies in the effort of international harmonization. This book represents an update of the first edition, as it covers regulatory novelties and accumulated experience in the regions already addressed. In addition, this new edition offers a wider international perspective: new chapters are included covering Advanced Therapy Medicinal Products regulations in India, Malaysia, Spain and Thailand, the European Pharmacopoeia texts for gene therapy medicinal products as well as international harmonization programs. Each chapter, authored by experts from various regulatory bodies throughout the international community, walks the reader through the applications of nonclinical research to translational clinical research to licensure and therapeutic use of these innovative products. More specifically, each chapter offers insights into fundamental considerations that are essential for developers of Advanced Therapy Medicinal Products in the areas of product quality, pharmacology and toxicology, clinical trial design and HTA pathways, as well as pertinent ‘must-know’ guidelines and regulations. Regulatory Aspects of Gene Therapy and Cell Therapy Products: a Global Perspective is part of the American Society of Gene & Cell Therapy sub-series of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students, clinicians, and researchers interested in gene and cell therapy and the regulation of pharmaceuticals.

Genetically Engineered Crops

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309437385
Total Pages : 607 pages
Book Rating : 4.3/5 (94 download)

DOWNLOAD NOW!

Book Synopsis Genetically Engineered Crops by : National Academies of Sciences, Engineering, and Medicine

Download or read book Genetically Engineered Crops written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-01-28 with total page 607 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.

Novel Designs of Early Phase Trials for Cancer Therapeutics

Author : Shivaani Kummar
Publisher : Academic Press
ISBN 13 : 0128125705
Total Pages : 234 pages
Book Rating : 4.1/5 (281 download)

DOWNLOAD NOW!

Book Synopsis Novel Designs of Early Phase Trials for Cancer Therapeutics by : Shivaani Kummar

Download or read book Novel Designs of Early Phase Trials for Cancer Therapeutics written by Shivaani Kummar and published by Academic Press. This book was released on 2018-05-22 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials. Brings a comprehensive review and recommendations for new clinical trial designs for modern cancer therapeutics Provides the reader with a better understanding on how to design and implement early phase oncology trials Presents a better and updated understanding of the process of developing new treatments for cancer, the exciting scientific advances and how they are informing drug development

Exploring Immune Variability in Susceptibility to Tuberculosis Infection in Humans

Author : Julie G. Burel
Publisher : Frontiers Media SA
ISBN 13 : 2889744051
Total Pages : 169 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!

Book Synopsis Exploring Immune Variability in Susceptibility to Tuberculosis Infection in Humans by : Julie G. Burel

Download or read book Exploring Immune Variability in Susceptibility to Tuberculosis Infection in Humans written by Julie G. Burel and published by Frontiers Media SA. This book was released on 2022-02-16 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Targeting Leukocyte Trafficking: Insights and Future Directions

Author : Helen Michelle McGettrick
Publisher : Frontiers Media SA
ISBN 13 : 2889742857
Total Pages : 172 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!

Book Synopsis Targeting Leukocyte Trafficking: Insights and Future Directions by : Helen Michelle McGettrick

Download or read book Targeting Leukocyte Trafficking: Insights and Future Directions written by Helen Michelle McGettrick and published by Frontiers Media SA. This book was released on 2022-02-04 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Interaction of Immune and Cancer Cells

Author : Magdalena Klink
Publisher : Springer Nature
ISBN 13 : 3030913112
Total Pages : 358 pages
Book Rating : 4.0/5 (39 download)

DOWNLOAD NOW!

Book Synopsis Interaction of Immune and Cancer Cells by : Magdalena Klink

Download or read book Interaction of Immune and Cancer Cells written by Magdalena Klink and published by Springer Nature. This book was released on 2022-02-14 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now, it its second edition, this book summarizes the role of immune cells in tumor suppression and progression. It describes in detail why tumor cells can survive and spread in spite of the antitumor response of immune cells. Since immunotherapy is an attractive approach to cancer therapy, this book also provides information on the two main strategies: monoclonal antibodies and adaptive T cell immunotherapy, with a focus on recent human clinical trials. A newly added chapter also focuses on the role of Natural Killer cells in tumor progression. The book provides a state-of-the-art, comprehensive overview of immune cells in cancer and is an indispensable resource for researchers and practitioners working or lecturing in the field of cancer research and immunology.

Genetic Technology: A New Frontier

Author : Assessment Office Of Technology
Publisher : CRC Press
ISBN 13 : 0429704798
Total Pages : 352 pages
Book Rating : 4.4/5 (297 download)

DOWNLOAD NOW!

Book Synopsis Genetic Technology: A New Frontier by : Assessment Office Of Technology

Download or read book Genetic Technology: A New Frontier written by Assessment Office Of Technology and published by CRC Press. This book was released on 2020-09-23 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1982 . This report examines the application of classical and molecular genetic technologies to micro-organisms, plants, and animals. This book is one of the first comprehensive documents on emerging genetic technologies and their implications for society. The authors discuss the opportunities and problems involved, describe current techniques, and attempt to project some of the economic, environmental, and institutional impacts of those techniques. The issues they raise go beyond those of technology, utility, and economic feasibility. As we gain the ability to manipulate life, we must face basic questions of just what life means and how far we can reasonably-and safely-allow ourselves to go.

Commercializing Successful Biomedical Technologies

Author : Shreefal S. Mehta
Publisher : Cambridge University Press
ISBN 13 : 1009302337
Total Pages : 457 pages
Book Rating : 4.0/5 (93 download)

DOWNLOAD NOW!

Book Synopsis Commercializing Successful Biomedical Technologies by : Shreefal S. Mehta

Download or read book Commercializing Successful Biomedical Technologies written by Shreefal S. Mehta and published by Cambridge University Press. This book was released on 2022-11-17 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transform your research into commercial biomedical products with this revised and updated second edition. Covering drugs, devices and diagnostics, this book provides a step-by-step introduction to the process of commercialization, and will allow you to create a realistic business plan to develop your ideas into approved biomedical technologies. This new edition includes: Over 25% new material, including practical tips on startup creation from experienced entrepreneurs. Tools for starting, growing and managing a new venture, including business planning and commercial strategy, pitching investors, and managing operations. Global real-world case studies, including emerging technologies such as regulated medical software and Artificial Intelligence (AI), offer insights into key challenges and help illustrate complex points. Tips and operational tools from established industry insiders, suitable for graduate students and new biomedical entrepreneurs.

Genome Editing and Engineering

Author : Krishnarao Appasani
Publisher : Cambridge University Press
ISBN 13 : 1107170370
Total Pages : 535 pages
Book Rating : 4.1/5 (71 download)

DOWNLOAD NOW!

Book Synopsis Genome Editing and Engineering by : Krishnarao Appasani

Download or read book Genome Editing and Engineering written by Krishnarao Appasani and published by Cambridge University Press. This book was released on 2018-08-23 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment.

Thymic Epithelial Cells: New Insights into the Essential Driving Force of T-Cell Differentiation

Author : Marita Bosticardo
Publisher : Frontiers Media SA
ISBN 13 : 2889714497
Total Pages : 177 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!

Book Synopsis Thymic Epithelial Cells: New Insights into the Essential Driving Force of T-Cell Differentiation by : Marita Bosticardo

Download or read book Thymic Epithelial Cells: New Insights into the Essential Driving Force of T-Cell Differentiation written by Marita Bosticardo and published by Frontiers Media SA. This book was released on 2021-09-30 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Immune Cell Lineage Reprogramming in Cancer

Author : Jianmei Wu Leavenworth
Publisher : Frontiers Media SA
ISBN 13 : 2889744736
Total Pages : 244 pages
Book Rating : 4.8/5 (897 download)

DOWNLOAD NOW!

Book Synopsis Immune Cell Lineage Reprogramming in Cancer by : Jianmei Wu Leavenworth

Download or read book Immune Cell Lineage Reprogramming in Cancer written by Jianmei Wu Leavenworth and published by Frontiers Media SA. This book was released on 2022-02-22 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topic Editor Dr. Lewis Shi received financial support from Varian Medical System, Inc. The other Topic Editors declare no competing interests with regard to the Research Topic subject.

New Frontiers and Applications of Synthetic Biology

Author : Vijai Singh
Publisher : Academic Press
ISBN 13 : 0323859860
Total Pages : 487 pages
Book Rating : 4.3/5 (238 download)

DOWNLOAD NOW!

Book Synopsis New Frontiers and Applications of Synthetic Biology by : Vijai Singh

Download or read book New Frontiers and Applications of Synthetic Biology written by Vijai Singh and published by Academic Press. This book was released on 2022-01-12 with total page 487 pages. Available in PDF, EPUB and Kindle. Book excerpt: New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more. This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas. Offers basic understanding and knowledge in several aspects of synthetic biology Covers state-of-the-art tools and technologies of synthetic biology, including promoter design, DNA synthesis, DNA sequencing, genome design, directed evolution, protein engineering, computational tools, phage design, CRISPR-Cas systems, and more Discusses the applications of synthetic biology for smart drugs, vaccines, therapeutics, drug discovery, self-assembled materials, cell free systems, microfluidics, and more

Gene Therapy for Cancer

Author : Kelly K. Hunt
Publisher : Springer Science & Business Media
ISBN 13 : 159745222X
Total Pages : 469 pages
Book Rating : 4.5/5 (974 download)

DOWNLOAD NOW!

Book Synopsis Gene Therapy for Cancer by : Kelly K. Hunt

Download or read book Gene Therapy for Cancer written by Kelly K. Hunt and published by Springer Science & Business Media. This book was released on 2007-10-26 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic. This book will prove valuable as the volume of preclinical and clinical data continues to increase.