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Neuroprotective Therapy For Stroke And Ischemic Disease
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Book Synopsis Neuroprotective Therapy for Stroke and Ischemic Disease by : Paul A. Lapchak
Download or read book Neuroprotective Therapy for Stroke and Ischemic Disease written by Paul A. Lapchak and published by Springer. This book was released on 2017-01-12 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: A critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in academia and industry, to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischemic diseases. Currently stroke can be successfully treated through the administration of a thrombolytic, but the therapeutic window is short and many patients are not able to receive treatment. Only about 30% of patients are "cured" by available treatments. In 5 sections, the proposed volume will explore historical and novel neuroprotection mechanisms and targets, new and combination therapies, as well as clinical trial design for some of the recent bench-side research.
Book Synopsis Magnesium in the Central Nervous System by : Robert Vink
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Book Synopsis Translational Stroke Research by : Paul A. Lapchak
Download or read book Translational Stroke Research written by Paul A. Lapchak and published by Springer Science & Business Media. This book was released on 2012-03-23 with total page 926 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume sets a basis for effective translational research. Authored by experts in the field of translational stroke research, each chapter specifically addresses one or more components of preclinical stroke research. The emphasis is placed on target identification and drug development using state-of-the-art in vitro and in vivo assays, in combination with in vitro toxicology assays, AMDE and clinical design.
Book Synopsis Ischemic Stroke Therapeutics by : Bruce Ovbiagele
Download or read book Ischemic Stroke Therapeutics written by Bruce Ovbiagele and published by Springer Nature. This book was released on with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Acute Ischemic Stroke by : R. Gilberto González
Download or read book Acute Ischemic Stroke written by R. Gilberto González and published by Springer Science & Business Media. This book was released on 2010-10-05 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.
Book Synopsis Thrombolytic Therapy for Acute Stroke by : Patrick D. Lyden
Download or read book Thrombolytic Therapy for Acute Stroke written by Patrick D. Lyden and published by Springer Science & Business Media. This book was released on 2007-11-08 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: It often takes time for a new therapeutic modality to mature into an accepted treatment option. After initial approval, new drugs, devices, and procedures all go through this process until they become “vetted” by the scientific community as well as the medical community at large. Thrombolysis for treatment of stroke is no exception. Thrombolytic Therapy for Acute Stroke, Second Edition comes four years after the first edition and provides a very comprehensive, updated perspective on the use of intravenous rt-TPA in acute stroke. The authors provide longer term follow-up on the pivotal clinical trials that led to Food and Drug Administration approval, data concerning phase 4 trials in larger numbers of patients, and, most importantly, the community experience that has accumulated since its release. They add to this the latest promising information concerning intra-arterial thrombolysis, which is still under investigation and more speculative sections concerning possible new avenues of clinical research such as combining intravenous thr- bolysis with neuroprotective therapies or intra-arterial thrombolysis. A wealth of factual information is supplemented by chapters containing sage opinion from Drs. Lyden and Caplan concerning the logistical, economic, and procedural issues that have been generated since the advent of this technology. Importantly, diagnosis does not take a back seat to therapeutics as illustrated by sections devoted to eva- ation of the stroke patient, very useful illustrative cases and clinical comments, and chapters on the latest in imaging as applied to this field.
Book Synopsis The Stroke Book by : Michel T. Torbey
Download or read book The Stroke Book written by Michel T. Torbey and published by Cambridge University Press. This book was released on 2013-07-18 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: An essential companion for busy professionals seeking to navigate stroke-related clinical situations successfully and make quick informed treatment decisions.
Book Synopsis Prevention and Treatment of Ischemic Stroke by : Scott Eric Kasner
Download or read book Prevention and Treatment of Ischemic Stroke written by Scott Eric Kasner and published by Butterworth-Heinemann. This book was released on 2004 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume covers prevention and treatment options for both primary and secondary ischemic stroke; offers practical, scientific guidance on all aspects of patient care, including critical care management and rehabilitation; provides author recommendations where clinical answers are not yet clear; and discusses topics such as diagnostic evaluation of TIA and ischemic stroke, large vessel atherosclerosis, small vessel occlusive disease, ususual and cryptogenic etiologies of stroke, and emerging therapies.
Book Synopsis Neuroprotection by : Matilde Otero-Losada
Download or read book Neuroprotection written by Matilde Otero-Losada and published by BoD – Books on Demand. This book was released on 2020-11-26 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neurological disease affects nearly 25%–30% of the world’s population, exerting enormous financial strain on the healthcare system. Estimated current costs are around $800 annual billion, and this number is expected to increase exponentially as the global population ages. As such, new and alternative neuroprotective strategies are urgently needed. This book examines some of the most promising approaches in neuroprotection as well as discusses current goals and prospects. Organized into three sections, chapters cover such topics as the use of cannabinoids, medicinal plants, and essential oils in Alzheimer’s and Parkinson’s; protein misfolding and the neuroprotective potential of vitamin E in cerebral ischemia; and potential new neurological treatments and their mechanisms of action.
Book Synopsis Evidence-Based Neurology by : Livia Candelise
Download or read book Evidence-Based Neurology written by Livia Candelise and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Evidence-based Neurology: Management of Neurological Disorders a carefully selected group of clinically experienced collaborators use the best available evidence to answer more than 100 clinical questions about the treatment and management of neurological disorders. Divided into three sections and 24 chapters, this book fills the gap between guidelines and primary studies as well as between primary and secondary scientific medical literature summarizes the most recent and important findings on treatments for neurological patients measures the benefit and, when applicable, the risk of harm inherent in specific neurological interventions. This unique, evidence-based text, edited by members of the Cochrane Neurological Network will be an essential resource for all general neurologists, from the novice to the most experienced, in their everyday clinical practice.
Download or read book Brain Ischemia written by Eugene I. Gusev and published by Springer Science & Business Media. This book was released on 2003-04-30 with total page 414 pages. Available in PDF, EPUB and Kindle. Book excerpt: Highlighting concepts of brain ischemia, this book looks at the molecular mechanisms of its development leading to brain tissue changes and describes strategies of neuroprotective therapy. Coverage includes cellular reactions in response to acute focal brain ischemia, microglial activation and local inflammation in focal brain ischemia, programmed cell death, primary and secondary neuroprotection, gangliosides, and modern therapeutic approaches to acute focal brain ischemia. The authors are neurologists affiliated with the Russian State Medical University. Annotation (c)2003 Book News, Inc., Portland, OR (booknews.com).
Book Synopsis Neuroprotective Effects of Phytochemicals in Neurological Disorders by : Tahira Farooqui
Download or read book Neuroprotective Effects of Phytochemicals in Neurological Disorders written by Tahira Farooqui and published by John Wiley & Sons. This book was released on 2017-01-03 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals are naturally occurring bioactive compounds found in edible fruits, plants, vegetables, and herbs. Unlike vitamins and minerals, phytochemicals are not needed for the maintenance of cell viability, but they play a vital role in protecting neural cells from inflammation and oxidative stress associated with normal aging and acute and chronic age-related brain diseases. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the advances in our understanding of the potential neuroprotective benefits that these naturally occurring chemicals contain. Neuroprotective Effects of Phytochemicals in Neurological Disorders explores the role that a number of plant-based chemical compounds play in a wide variety of neurological disorders. Chapters explore the impact of phytochemicals on neurotraumatic disorders, such as stroke and spinal cord injury, alongside neurodegenerative diseases such as Alzheimer's and Parkinson's Disease, as well as neuropsychiatric disorders such as depression and schizophrenia. The chapters and sections of this book provide the reader with a big picture view of this field of research. Neuroprotective Effects of Phytochemicals in Neurological Disorders aims to present readers with a comprehensive and cutting edge look at the effects of phytochemicals on the brain and neurological disorders in a manner useful to researchers, neuroscientists, clinical nutritionists, and physicians.
Book Synopsis Translational Research in Stroke by : Paul A. Lapchak
Download or read book Translational Research in Stroke written by Paul A. Lapchak and published by Springer. This book was released on 2017-12-20 with total page 581 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book mainly discusses the current status of stroke transnational research and allows the reader to understand the interplay of common comorbidities in the stroke population such as diabetes and hypertension, and provides insight into stroke targets to promote cell survival, angiogenesis, neurogenesis, and most importantly, functional recovery after stroke. Throughout the world, stroke is still a leading cause of mortality and morbidity; each year approximately 15 million people worldwide suffer from stroke. Stroke is now the leading cause of death and disability in China. Large communities of stroke survivors are eagerly awaiting scientific advances in transnational stroke research that would offer neuroprotective therapeutics for acute stroke management, or rehabilitation and regenerative strategies utilizing novel stem cell-based approaches. While research is ongoing, the Editors have compiled this volume to help the further understanding of the pathophysiology of stroke and to review and identify future potential biomarkers. The book is written for students, researchers and physicians in neurosciences, neurology and neuroradiology.
Download or read book Ischemic Stroke written by Chung Y. Hsu and published by Karger Medical and Scientific Publishers. This book was released on 1998 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: '... Provides an admirable review of current knowledge regarding experimental stroke research, and outlines the problems and some solutions in the clinical application of such knowledge.'
Book Synopsis The Handbook of Neuroprotection by : Kewal K. Jain
Download or read book The Handbook of Neuroprotection written by Kewal K. Jain and published by Springer Science & Business Media. This book was released on 2011-02-14 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuroprotection has been placed on a firm scientific basis during the past decade due to an improved understanding of the molecular basis of neurological diseases and the knowledge that treatment of neurological disorders should not be merely symptomatic but preventative against the progression of the underlying disease, as well as regenerative. The Handbook of Neuroprotection serves as a comprehensive review of neuroprotection based on knowledge of the molecular basis of neurological disorders. Neuroprotective effects of older, established drugs, as well as new drugs in development, are well documented in this detailed volume, featuring the most cutting-edge and innovative methods currently in use. In-depth and authoritative, The Handbook of Neuroprotection features a compendium of vital knowledge aimed at providing researchers with an essential reference for this key neurological area of study.
Book Synopsis Acute Stroke Treatment by : Julien Bogousslavsky
Download or read book Acute Stroke Treatment written by Julien Bogousslavsky and published by CRC Press. This book was released on 1997-09-04 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Owing to the increased interest in brain ischemia and the new therapeutic options from pharmaceutical companies for the treatment of acute stroke, Professor Julien Bogousslavsky, one of the world's stroke experts, has revised his best-selling book. It is the emergence of huge possibilities in the management of stroke - ultra-early diagnosis, intensive care, surgical and other interventional therapies, thrombolysis, anti-ischemic drugs and prevention of immediate recurrence - which necessiates this timely update.
Book Synopsis Textbook of Stroke Medicine by : Michael Brainin
Download or read book Textbook of Stroke Medicine written by Michael Brainin and published by Cambridge University Press. This book was released on 2014-09-11 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.