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Neuroprogression And Staging In Bipolar Disorder
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Book Synopsis Neuroprogression and Staging in Bipolar Disorder by : Flávio Kapczinski
Download or read book Neuroprogression and Staging in Bipolar Disorder written by Flávio Kapczinski and published by Oxford University Press, USA. This book was released on 2015 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a solid and in-depth outline that can be used to influence research and practice in the field of bipolar disorder. This book would be of use to anyone working with mood disorders, and serves as a valuable resource for both researchers interested in bipolar disorder and clinicians involved in the day-to-day management of patientswithh this condition.--
Book Synopsis Neuroprogression in Psychiatry by : Flávio Kapczinski
Download or read book Neuroprogression in Psychiatry written by Flávio Kapczinski and published by Oxford University Press. This book was released on 2019-03-05 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.
Book Synopsis Bipolar Disorder Vulnerability by : Jair Soares
Download or read book Bipolar Disorder Vulnerability written by Jair Soares and published by Academic Press. This book was released on 2018-06-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.
Book Synopsis Clinical Staging in Psychiatry by : Patrick D. McGorry
Download or read book Clinical Staging in Psychiatry written by Patrick D. McGorry and published by Cambridge University Press. This book was released on 2019-08-29 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical staging is a solution to transform psychiatric diagnosis and improve mental health outcomes.
Book Synopsis Neurobiology of Bipolar Disorder by : Joao Quevedo
Download or read book Neurobiology of Bipolar Disorder written by Joao Quevedo and published by Academic Press. This book was released on 2020-11-25 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder
Book Synopsis The Treatment of Bipolar Disorder by : André F. Carvalho
Download or read book The Treatment of Bipolar Disorder written by André F. Carvalho and published by Oxford University Press. This book was released on 2017-03-01 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar disorder is a chronic and debilitating mental illness affecting a significant proportion of the world's population. It is associated with significant impairments in health-related quality of life and psychosocial functioning, and has significant illness-related morbidity and heightened mortality rates due to medical comorbidities and suicide. The management of this disorder requires a complex combination of pharmacological and psychosocial interventions which can be challenging for clinicians. Written by world experts in the field of bipolar disorder, The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions provides readers with a concise and comprehensive guide to the integrative management of bipolar disorder. This resource contains 31 chapters on the various management choices available, from both established and novel treatment areas, such as psychoeducation, psychotherapeutic interventions, neuromodulatory approaches and novel therapeutic targets. The complexity and diversity of the management choices available makes this a continually evolving field and necessitates forward thinking. By both discussing the current management of bipolar disorder, and the future developments available, this resource provides all clinicians working with patients with bipolar disorder an up-to-date and reflective guide to its management and what the future holds.
Book Synopsis Neuroprogression and Staging in Bipolar Disorder by : Flávio Kapczinski
Download or read book Neuroprogression and Staging in Bipolar Disorder written by Flávio Kapczinski and published by OUP Oxford. This book was released on 2015-06-11 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the original proposals of staging for psychotic disorders developed by McGorry and colleagues, a few systems have been put forward specifically for people with bipolar disorder. There is now consistent evidence that, at least for a significant portion of people with this disease, clinical course and outcome are not as benign as initially described. The evidence thus far points to relevant differences between early and late stages of bipolar disorders in the clinical course of illness, neurobiology and systemic pathology. These differences all suggest that staging is a viable addition to clinical care in bipolar disorder. Neuroprogression and Staging in Bipolar Disorder provides a comprehensive summary of the current state of the evidence regarding the use of staging systems in bipolar disorder. Edited by the leading researchers in the field, the book systematically covers the theoretical basis for staging, comparisons between different proposals, neurobiological underpinnings, the current evidence-base, limitations and future directions, and clinical implications and recommendations for practice. The book provides a solid and in-depth outline and thus to influence research and practice in the field of bipolar disorder.
Download or read book Mood Disorders written by Ather Muneer and published by Routledge. This book was released on 2018-02-01 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mood Disorders: Practical Issues in Diagnosis and Management provides cutting edge knowledge about the diagnosis and treatment of principal mood disorders, namely major depressive disorder and bipolar disorder. Covering diagnosis, differentiating features, and illness course and trajectories of principal mood disorders, Dr. Ather Muneer provides essential information in a succinct and practical manner, while highlighting significant new findings in the area. This book will help a broad range of mental health professionals better treat the millions of people with mood disorders across the globe.
Book Synopsis The Science and Practice of Lithium Therapy by : Gin S. Malhi
Download or read book The Science and Practice of Lithium Therapy written by Gin S. Malhi and published by Springer. This book was released on 2016-11-24 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide, and those that are recipients of lithium therapy.
Book Synopsis Bipolar Disorder: From Neuroscience to Treatment by : Allan H. Young
Download or read book Bipolar Disorder: From Neuroscience to Treatment written by Allan H. Young and published by Springer Nature. This book was released on 2021-03-29 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry. Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously. With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.
Book Synopsis Bipolar Disorder in Older Age Patients by : Susan W. Lehmann
Download or read book Bipolar Disorder in Older Age Patients written by Susan W. Lehmann and published by Springer. This book was released on 2017-01-05 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive but practical understanding of the clinical approach to evaluating and caring for older people with bipolar disorder. Aspects of aging that impact the diagnosis, clinical course, and management of bipolar disorder are explained; in particular, attention is drawn to the implications of comorbidities and medical complexity for the psychiatric care of older individuals with the disorder. On the other hand, similarities to treatment in younger patients are also identified. The coverage includes thorough review of current research in the field. Clinical case vignettes are used throughout to highlight practical points, and each chapter includes “clinical pearls” that summarize key points for the clinician. The book closes by examining anticipated research directions and the future needs of this patient population. Bipolar Disorder in Older Age Patients will be an ideal update for the practicing community or geriatric psychiatrist working with older patients with bipolar disorder.
Book Synopsis Functional Remediation for Bipolar Disorder by : Eduard Vieta
Download or read book Functional Remediation for Bipolar Disorder written by Eduard Vieta and published by Cambridge University Press. This book was released on 2014-12-11 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a novel, evidence-based psychological intervention to help therapists manage cognitive and functional deficits in bipolar disorder patients.
Book Synopsis Biomarkers in Bipolar Disorders by : Rodrigo Machado-Vieira
Download or read book Biomarkers in Bipolar Disorders written by Rodrigo Machado-Vieira and published by Academic Press. This book was released on 2022-01-16 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomarkers in Bipolar Disorders summarizes cutting-edge findings in biomarkers' research, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings cover different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes), prediction of treatment response and follow-up outcomes, along with the most promising perspectives in each area. Each section includes a comprehensive and focused overview on the state-of-the-art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder. Describes strategies for the biomarker discovery of relevant proteins differentially expressed in Bipolar Disorder Presents techniques and main findings in transcriptome research related to CNS synaptic function Provides an overview on current behavioral strategies and their validity in drug development in Bipolar Disorder Discusses current genetic findings, integrating tests for treatments leading to personalized treatments
Book Synopsis Inflammation and Immunity in Depression by : Bernhard Baune
Download or read book Inflammation and Immunity in Depression written by Bernhard Baune and published by Academic Press. This book was released on 2018-05-23 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation and Immunity in Depression: Basic Science and Clinical Applications is the first book to move beyond the established theory of cytokine-induced depression and explore the broader role the immune system plays in this devastating mood disorder. The book fully explores the most recent lines of research into this rapidly advancing field, including alterations of T-cells, the neurobiological implications of neuroinflammation and immune alterations for brain development and function, and the genetic components of neuroinflammation in depression, including the relationships between stress and inflammation that are revealing gene-environment interactions in the disorder. Combining contributions from researchers worldwide, this book provides the most comprehensive discussion available today on the involvement of the innate immune and adaptive immune systems in depressive disorder. Chapters span neuroscience, psychology, clinical applications and future directions, making this book an invaluable resource for advanced students, researchers and practitioners who need to understand the complex and varied role of inflammation and immune responses in depression. Synthesizes current knowledge of inflammation and immunity in depression, ranging from basic neuroscience research, to clinical applications in psychiatry Expands on the long-established theory of cytokine-induced depression to discuss broader involvement of the immune system Explores translational potential of targeting immune dysfunction for clinical interventions
Book Synopsis Practical Psychopharmacology by : Joseph F. Goldberg
Download or read book Practical Psychopharmacology written by Joseph F. Goldberg and published by Cambridge University Press. This book was released on 2021-04-29 with total page 611 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide translating clinical trials findings, across major psychiatric disorders, to devise tailored, evidence-based treatments.
Book Synopsis Eating Disorders and Obesity in Children and Adolescents by : Johannes Hebebrand
Download or read book Eating Disorders and Obesity in Children and Adolescents written by Johannes Hebebrand and published by Elsevier Health Sciences. This book was released on 2018-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get a quick, expert overview of best practices for diagnosis and treatment of eating disorders in children and adolescents. This concise resource by Drs. Johannes Hebebrand and Beate Herpertz-Dahlmann provides psychiatrists and pediatricians with current information in this increasingly important field, including practical sections on developmental aspects of eating disorders, symptomology, epidemiology, etiology and pathyphysiology, treatment and outcomes, and prevention. Discusses general concepts for feeding, eating, and weight disorders; body weight and composition, appetite regulation, and the emergence of body perception and image. Covers genetics of eating and weight disorders, influence of hormones, intergenerational effects, and food addiction. Includes information on cognitive behavioral therapy, family-based therapies, early intervention, pharmacotherapy, bariatric surgery, and other treatments. Consolidates today’s available information on this timely topic into a single convenient resource.
Book Synopsis Personalized Psychiatry by : Ives Cavalcante Passos
Download or read book Personalized Psychiatry written by Ives Cavalcante Passos and published by Springer. This book was released on 2019-02-12 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book integrates the concepts of big data analytics into mental health practice and research. Mental disorders represent a public health challenge of staggering proportions. According to the most recent Global Burden of Disease study, psychiatric disorders constitute the leading cause of years lost to disability. The high morbidity and mortality related to these conditions are proportional to the potential for overall health gains if mental disorders can be more effectively diagnosed and treated. In order to fill these gaps, analysis in science, industry, and government seeks to use big data for a variety of problems, including clinical outcomes and diagnosis in psychiatry. Multiple mental healthcare providers and research laboratories are increasingly using large data sets to fulfill their mission. Briefly, big data is characterized by high volume, high velocity, variety and veracity of information, and to be useful it must be analyzed, interpreted, and acted upon. As such, focus has to shift to new analytical tools from the field of machine learning that will be critical for anyone practicing medicine, psychiatry and behavioral sciences in the 21st century. Big data analytics is gaining traction in psychiatric research, being used to provide predictive models for both clinical practice and public health systems. As compared with traditional statistical methods that provide primarily average group-level results, big data analytics allows predictions and stratification of clinical outcomes at an individual subject level. Personalized Psychiatry – Big Data Analytics in Mental Health provides a unique opportunity to showcase innovative solutions tackling complex problems in mental health using big data and machine learning. It represents an interesting platform to work with key opinion leaders to document current achievements, introduce new concepts as well as project the future role of big data and machine learning in mental health.
