Neurons And The Dha Principle

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Neurons and the DHA Principle

Author : Raymond C. Valentine
Publisher : CRC Press
ISBN 13 : 1439874875
Total Pages : 287 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Neurons and the DHA Principle by : Raymond C. Valentine

Download or read book Neurons and the DHA Principle written by Raymond C. Valentine and published by CRC Press. This book was released on 2012-10-26 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies with bacteria and other systems suggest that the omega-3 fatty acid DHA confers great benefits to neurons in maximizing both speed of neural impulses and energy efficiency. Unfortunately, studies also show that DHA’s ease of oxidation damages membrane integrity. Exploring this duality, Neurons and the DHA Principle proposes a new model for the causes of neurodegeneration, in which DHA-enriched membranes of neurons become dysfunctional and energetically wasteful, triggering the premature death of neurons. The challenge of this book is to digest how DHA acts as an essential building block of neurons while also conspiring for their assassination during aging. As the book reviews the extraordinary properties of DHA in life forms from deep-sea bacteria to human neurons, it asks: Is there a trade-off between speed and efficiency of brain function enabled by DHA versus longevity or life span? Has modern medicine advanced significantly in the treatment of the body but not necessarily of the brain? What are the molecular explanations for the decline in brain health during the age of longevity? A full accounting of the roles of DHA in neurons requires balancing the enormous benefits of these molecules against the risks. Introducing the dual chemical personalities of DHA from an evolutionary perspective, Neurons and the DHA Principle explores DHA from the standpoint of benefit–risk analysis, opening new perspectives for understanding how DHA functions in neurons.

Omega-3 Fatty Acids and the DHA Principle

Author : Raymond C. Valentine
Publisher : CRC Press
ISBN 13 : 1439813000
Total Pages : 278 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Omega-3 Fatty Acids and the DHA Principle by : Raymond C. Valentine

Download or read book Omega-3 Fatty Acids and the DHA Principle written by Raymond C. Valentine and published by CRC Press. This book was released on 2009-12-03 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: The physical-chemical properties of the omega-3 fatty acid DHA (docosahexaenoic acid) enable it to facilitate rapid biochemical processes in the membrane. This effect has numerous benefits, including those involved in the growth of bacteria, rapid energy generation, human vision, brain impulse, and photosynthesis, to name a few. Yet DHA also carries risks that can lead to cellular death and disease. Omega-3 Fatty Acids and the DHA Principle explores the roles of omega-3 fatty acids in cellular membranes ranging from human neurons and swimming sperm to deep sea bacteria, and develops a principle by which to assess their benefits and risks. The DHA Principle states that the blending of lipids to form cellular membranes is evolutionarily-honed to maximize benefit while minimizing risk, and that a complex blending code involving conformational dynamics, energy stress, energy yield, and chemical stability underlies all cellular membranes. This book lays the groundwork to understanding this code. It examines the evolution of DHA and the membrane and explores the general properties of omega-3s and other membrane lipids. It then focuses on cellular biology before shifting to a practical discussion on applications. The authors discuss the DHA Principle as applied to petroleum degradation, winemaking, global warming, molecular farming, aging, neurodegenerative diseases, and the prevention of colon cancer. Reflecting the increased public interest that has emerged over the years, this volume uses an integrative approach to explain the complex roles of omega-3s in the membrane. Incorporating principles from chemistry, cellular biology, evolution, and ecology, this work gives researchers in a variety of fields the building blocks to stimulate further study.

Human Longevity

Author : Raymond C. Valentine
Publisher : CRC Press
ISBN 13 : 146659487X
Total Pages : 259 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Human Longevity by : Raymond C. Valentine

Download or read book Human Longevity written by Raymond C. Valentine and published by CRC Press. This book was released on 2014-09-18 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman’s famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging. Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington’s disease, Parkinson’s disease, and traumatic brain disease in animal models of neurodegeneration. This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity.

Omega Fatty Acids in Brain and Neurological Health

Author : Ronald Ross Watson
Publisher : Academic Press
ISBN 13 : 0128152397
Total Pages : 518 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Omega Fatty Acids in Brain and Neurological Health by : Ronald Ross Watson

Download or read book Omega Fatty Acids in Brain and Neurological Health written by Ronald Ross Watson and published by Academic Press. This book was released on 2019-06-12 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases. Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements

Principles of Orthomolecularism

Author : R. A. S. Hemat
Publisher : Urotext
ISBN 13 : 1903737052
Total Pages : 489 pages
Book Rating : 4.9/5 (37 download)

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Book Synopsis Principles of Orthomolecularism by : R. A. S. Hemat

Download or read book Principles of Orthomolecularism written by R. A. S. Hemat and published by Urotext. This book was released on 2004 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Neural Development

Author : Dale Purves
Publisher : Sinauer Associates, Incorporated
ISBN 13 :
Total Pages : 456 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Principles of Neural Development by : Dale Purves

Download or read book Principles of Neural Development written by Dale Purves and published by Sinauer Associates, Incorporated. This book was released on 1985 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles of Nutrigenetics and Nutrigenomics

Author : Raffaele De Caterina
Publisher : Academic Press
ISBN 13 : 0128045876
Total Pages : 586 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Principles of Nutrigenetics and Nutrigenomics by : Raffaele De Caterina

Download or read book Principles of Nutrigenetics and Nutrigenomics written by Raffaele De Caterina and published by Academic Press. This book was released on 2019-09-22 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from the most well-cited researchers conducting groundbreaking research in the field, the book covers how the genetic makeup influences the response to foods and nutrients and how nutrients affect gene expression. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that helps to translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. Uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomics Includes a valuable guide to ethics for genetic testing for nutritional advice Chapters include definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts Companion website includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book

Principles of Modern Urology

Author : R.A.S Hemat
Publisher : Urotext
ISBN 13 : 1903737079
Total Pages : 600 pages
Book Rating : 4.9/5 (37 download)

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Book Synopsis Principles of Modern Urology by : R.A.S Hemat

Download or read book Principles of Modern Urology written by R.A.S Hemat and published by Urotext. This book was released on 1998-12-31 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Modern Urology is an authorative guide to urology and integrated urology. Principles of Modern Urology is an advanced urological textbook. This book begins by showing you how to implement your pathobiology, anatomy and physiology into practical simple approach to every client you meet. This book was written for medical student, resident and professional in medicine and especially urology. The author had adapted his proven teaching strategies into a unique approach that makes integrated urology accessible, and provides the foundations for understanding urology based upon the principles of structural pathobiology. Principles of Modern Urology presents well-integrated and practical approach to most urological condition. It is a versatile retrievable e-book. Principles of Modern Urology provides the reader with current concepts of the pathobiology and interventions for diseases. Anatomy, physiology, and radiology are also included within specific topical chapters. Principles of Modern Urology is based on the extensive international clinical and teaching experience of the author, both in traditional and integrated systems of medical schools.

Principles of Neural Coding

Author : Rodrigo Quian Quiroga
Publisher : CRC Press
ISBN 13 : 1439853312
Total Pages : 625 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Principles of Neural Coding by : Rodrigo Quian Quiroga

Download or read book Principles of Neural Coding written by Rodrigo Quian Quiroga and published by CRC Press. This book was released on 2013-05-06 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding how populations of neurons encode information is the challenge faced by researchers in the field of neural coding. Focusing on the many mysteries and marvels of the mind has prompted a prominent team of experts in the field to put their heads together and fire up a book on the subject. Simply titled Principles of Neural Coding, this b

Endothelial Cell Plasticity in the Normal and Injured Central Nervous System

Author : Esperanza Meléndez Herrera
Publisher : CRC Press
ISBN 13 : 1466599235
Total Pages : 270 pages
Book Rating : 4.4/5 (665 download)

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Book Synopsis Endothelial Cell Plasticity in the Normal and Injured Central Nervous System by : Esperanza Meléndez Herrera

Download or read book Endothelial Cell Plasticity in the Normal and Injured Central Nervous System written by Esperanza Meléndez Herrera and published by CRC Press. This book was released on 2015-01-28 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the importance of endothelial cells as key players in the functioning of the nervous system under both normal and pathological conditions. The book demonstrates that endothelial cells are an essential and dynamic cell population in the central nervous system, with multiple and complex roles, not only in the maintenance of homeostasis, but also in the regulation of important processes. These include neurogenesis, neural control of reproduction, aging, neurodegeneration, and tumor invasion. The book exhaustively reviews the newest findings in this exciting new area of investigation.

Rossi's Principles of Transfusion Medicine

Author : Toby L. Simon
Publisher : John Wiley & Sons
ISBN 13 : 1119719755
Total Pages : 740 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Rossi's Principles of Transfusion Medicine by : Toby L. Simon

Download or read book Rossi's Principles of Transfusion Medicine written by Toby L. Simon and published by John Wiley & Sons. This book was released on 2022-08-15 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: ROSSI’S PRINCIPLES OF TRANSFUSION MEDICINE Transfusion Medicine impacts patients with hematologic, oncologic, and surgical conditions as well as all areas of critical care medicine and multiple areas of chronic care. This book aims to be the single best source for information related to any aspect or application of Transfusion Medicine. Contributors for the sixth edition have once again been drawn from various scientific, medical, and surgical disciplines. Thus, this book ranges from encouraging and managing donors, to collecting and preserving the blood, to matching it to the appropriate recipient, all the way to its clinical uses. It also extends these concepts to implantable tissue and regenerative medicine. Other sample topics covered within the work include: Contemporary issues in donation and transfusion: patient blood management, clinical and technical aspects of blood administration, and donor and patient Hemovigilance Blood components and derivatives: red blood cell metabolism, preservation and oxygen delivery, blood groups, and composition of plasma Apheresis, transplantation, and new therapies: hematopoietic growth factors, therapeutic phlebotomy and cellular apheresis, HLA antigens, alleles, and antibodies How Transfusion Medicine has been affected by the coronavirus pandemic, the role of pathogen reduction and other modern trends This book serves as a complete and comprehensive resource on Transfusion Medicine for clinicians who prescribe blood, students who expect to enter clinical practice, and for the scientists, physicians, nurses, technologists, and others who assure the quality and availability of blood services.

Polyunsaturated Fatty Acid Metabolism

Author : Graham C. Burdge
Publisher : Elsevier
ISBN 13 : 012811231X
Total Pages : 252 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Polyunsaturated Fatty Acid Metabolism by : Graham C. Burdge

Download or read book Polyunsaturated Fatty Acid Metabolism written by Graham C. Burdge and published by Elsevier. This book was released on 2018-05-04 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyunsaturated Fatty Acid Metabolism explores a number of major roles of PUFA in the body, including its role as a component of cell membranes and how it provides substrates for the synthesis of lipid second messengers. Recent studies are unraveling the effect of interactions between diet and endocrine factors and genetic and epigenetic variation on the regulation of PUFA biosynthesis in animals. Together, these recent findings provide novel insights into the impact of differences in PUFA supply on health. This book captures these findings in a manner that marks the state-of-the-art, placing them in the wider context of PUFA metabolism and nutritional science. Users will find a comprehensive discussion on the topic that presents the contributions of leading researchers who combine their knowledge to create a cohesive academic resource for researchers, those involved in production, and health policymakers. Provides a comprehensive view of polyunsaturated fatty acid metabolism Describes underlying metabolism on lipids that include polyunsaturated fatty acids Includes discussions on recent findings on the genetic and epigenetic regulation of polyunsaturated fatty acid metabolism

Principles of Cellular, Molecular, and Developmental Neuroscience

Author : Oswald Steward
Publisher :
ISBN 13 :
Total Pages : 282 pages
Book Rating : 4.:/5 (45 download)

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Book Synopsis Principles of Cellular, Molecular, and Developmental Neuroscience by : Oswald Steward

Download or read book Principles of Cellular, Molecular, and Developmental Neuroscience written by Oswald Steward and published by . This book was released on 1989 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Buddha's Brain

Author : Rick Hanson
Publisher : ReadHowYouWant.com
ISBN 13 : 1459624157
Total Pages : 350 pages
Book Rating : 4.4/5 (596 download)

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Book Synopsis Buddha's Brain by : Rick Hanson

Download or read book Buddha's Brain written by Rick Hanson and published by ReadHowYouWant.com. This book was released on 2011-07-13 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jesus, Moses, Mohammed, Gandhi, and the Buddha all had brains built essentially like anyone else's, yet they were able to harness their thoughts and shape their patterns of thinking in ways that changed history. With new breakthroughs in modern neuroscience and the wisdom of thousands of years of contemplative practice, it is possible for us to shape our own thoughts in a similar way for greater happiness, love, compassion, and wisdom. Buddha's Brain joins the forces of modern neuroscience with ancient contemplative teachings to show readers how they can work toward greater emotional well-being, healthier relationships, more effective actions, and deepened religious and spiritual understanding. This book will explain how the core elements of both psychological well-being and religious or spiritual life-virtue, mindfulness, and wisdom--are based in the core functions of the brain: regulating, learning, and valuing. Readers will also learn practical ways to apply this information, as the book offers many exercises they can do to tap the unused potential of the brain and rewire it over time for greater peace and well-being.

The Omega Principle

Author : Paul Greenberg
Publisher : Penguin
ISBN 13 : 0698183460
Total Pages : 276 pages
Book Rating : 4.6/5 (981 download)

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Book Synopsis The Omega Principle by : Paul Greenberg

Download or read book The Omega Principle written by Paul Greenberg and published by Penguin. This book was released on 2018-07-10 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: By the bestselling author of Four Fish and American Catch, an eye-opening investigation of the history, science, and business behind omega-3 fatty acids, the "miracle compound" whose story is intertwined with human health and the future of our planet Omega-3 fatty acids have long been celebrated by doctors and dieticians as key to a healthy heart and a sharper brain. In the last few decades, that promise has been encapsulated in one of America's most popular dietary supplements. Omega-3s are today a multi-billion dollar business, and sales are still growing apace--even as recent medical studies caution that the promise of omega-3s may not be what it first appeared. But a closer look at the omega-3 sensation reveals something much deeper and more troubling. The miracle pill is only the latest product of the reduction industry, a vast, global endeavor that over the last century has boiled down trillions of pounds of marine life into animal feed, fertilizer, margarine, and dietary supplements. The creatures that are the victims of that industry seem insignificant to the untrained eye, but turn out to be essential to the survival of whales, penguins, and fish of all kinds, including many that we love to eat. Behind these tiny molecules is a big story: of the push-and-pull of science and business; of the fate of our oceans in a human-dominated age; of the explosion of land food at the expense of healthier and more sustainable seafood; of the human quest for health and long life at all costs. James Beard Award-winning author Paul Greenberg probes the rich and surprising history of omega-3s--from the dawn of complex life, when these compounds were first formed; to human prehistory, when the discovery of seafood may have produced major cognitive leaps for our species; and on to the modern era, when omega-3s may point the way to a bold new direction for our food system. With wit and boundless curiosity, Greenberg brings us along on his travels--from Peru to Antarctica, from the Canary Islands to the Amalfi Coast--to reveal firsthand the practice and repercussions of our unbalanced way of eating. Rigorously reported and winningly told, The Omega Principle is a powerful argument for a more deliberate and forward-thinking relationship to the food we eat and the oceans that sustain us.

Survival of the Fattest

Author : Stephen C. Cunnane
Publisher : World Scientific
ISBN 13 : 9812567704
Total Pages : 363 pages
Book Rating : 4.8/5 (125 download)

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Book Synopsis Survival of the Fattest by : Stephen C. Cunnane

Download or read book Survival of the Fattest written by Stephen C. Cunnane and published by World Scientific. This book was released on 2005 with total page 363 pages. Available in PDF, EPUB and Kindle. Book excerpt: How did humans evolve larger and more sophisticated brains? In general, evolution depends on a special combination of circumstances: part genetics, part time, and part environment. In the case of human brain evolution, the main environmental influence was adaptation to a OCyshore-basedOCO diet, which provided the worldOCOs richest source of nutrition, as well as a sedentary lifestyle that promoted fat deposition. Such a diet included shellfish, fish, marsh plants, frogs, birdOCOs eggs, etc. Humans and, and more importantly, hominid babies started to get fat, a crucial distinction that led to the development of larger brains and to the evolution of modern humans. A larger brain is expensive to maintain and this increasing demand for energy results in, succinctly, survival of the fattest."

Principles of Neural Science

Author : Eric R. Kandel
Publisher :
ISBN 13 : 9781264267682
Total Pages : 1646 pages
Book Rating : 4.2/5 (676 download)

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Book Synopsis Principles of Neural Science by : Eric R. Kandel

Download or read book Principles of Neural Science written by Eric R. Kandel and published by . This book was released on 2021 with total page 1646 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this sixth edition of Principles of Neural Science is to provide readers with insight into how genes, molecules, neurons, and the circuits they form give rise to behavior. With the exponential growth in neuroscience research over the 40 years since the first edition of this book, an increasing challenge is to provide a comprehensive overview of the field while remaining true to the original goal of the first edition, which is to elevate imparting basic principles over detailed encyclopedic knowledge.