Neural Regulation Of Metabolism

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Neural Regulation of Metabolism

Author : Qi Wu
Publisher : Springer
ISBN 13 : 9811312869
Total Pages : 233 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Neural Regulation of Metabolism by : Qi Wu

Download or read book Neural Regulation of Metabolism written by Qi Wu and published by Springer. This book was released on 2018-11-02 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.

Neuron Signaling in Metabolic Regulation

Author : Qingchun Tong
Publisher : CRC Press
ISBN 13 : 100036691X
Total Pages : 330 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Neuron Signaling in Metabolic Regulation by : Qingchun Tong

Download or read book Neuron Signaling in Metabolic Regulation written by Qingchun Tong and published by CRC Press. This book was released on 2021-06-07 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on neuron signaling in the regulation of metabolism and body weight, and especially on methods used in these studies. Obesity and related metabolic syndromes have reached epidemic status, but still are no effective strategies for prevention and treatment. Body weight homeostasis is maintained by balanced food intake and energy expenditure, both of which are under the control of brain neurons. In the recent years, significant progress has been made in identifying specific neurons, neural pathways, and non-neuron cells in feeding regulation, as well as in delineating autonomic nervous systems targeting peripheral metabolic tissues in the regulation of energy expenditure and metabolism. This book reviews recent progress on important neuron signaling for body weight and metabolic regulation and the state-of-the-art methods that has been applied in this field, ranging from animal models with neuron-specific manipulations, pharmacology, optogenetics, in vivo Ca2+ imaging, and viral tracing. Readers will be exposed to latest research frontiers on neuron regulation of metabolism. Key Features Explores the role signaling between neurons plays with respect to metabolism Documents how neurotransmitters affect the regulation of feeding Describes various methods and technologies used to study the neuronal control of metabolism Includes contributions from an international team of leading researchers. Related Titles Lim, W. & B. Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Feltz, A. Physiology of Neurons (ISBN 978-0-8153-4600-5) Zempleni, J. & K. Dakshinamurti, eds. Nutrients and Cell Signaling (ISBN 978-0367-39307-6)

Central Nervous System

Author : E. Genazzani
Publisher : Springer Science & Business Media
ISBN 13 : 3642657141
Total Pages : 252 pages
Book Rating : 4.6/5 (426 download)

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Book Synopsis Central Nervous System by : E. Genazzani

Download or read book Central Nervous System written by E. Genazzani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the Symposium "Metabolic Regulation and Functional Activity in the Central Nervous System" which was held on September 16 and 17, 1972, at Saint Vincent (Aosta)/Italy, and was sponsored by the Accademia di Medicina di Torino with the scientific cooperation of the Istituto di Farmacologia, Universita di Torino, and the Pharmakologisches Institut der Freien Universitat Berlin. Its purpose was to give a greater number of scientists from different countries an opportunity to report their latest results under a heading concerning general relationships between metabolism and function. We quite deliberately refrained from pursuing the partly heterogenous subjects into details. Thus, the organizers hoped to be able to interest a greater circle of readers for the manifold subjects from various fields dealing with the investigation of metabolic processes in the central nervous system. The discussion remarks to the lectures could not be considered for printing. The Accademia di Medicina di Torino and all others concerned do not only thank Dr. R. Di Carlo and other members of the Istituto di Farmacologia, Universita di Torino, for the excellent work they performed in preparing this Symposium, but also the Amministrazione Regionale della Valle di Aosta and SIT A V di Saint-Vincent for their generous support and their kind hospitality which made the stay at Saint-Vincent most agreeable for all participants.

Neural Metabolism In Vivo

Author : In-Young Choi
Publisher : Springer Science & Business Media
ISBN 13 : 1461417872
Total Pages : 1168 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Neural Metabolism In Vivo by : In-Young Choi

Download or read book Neural Metabolism In Vivo written by In-Young Choi and published by Springer Science & Business Media. This book was released on 2012-03-14 with total page 1168 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the preface: “Neural Metabolism In Vivo aims to provide a comprehensive overview of neurobiology by presenting the basic principles of up-to-date and cutting-edge technology, as well as their application in assessing the functional, morphological and metabolic aspects of the brain. Investigation of neural activity of the living brain via neurovascular coupling using multimodal imaging techniques extended our understanding of fundamental neurophysiological mechanisms, regulation of cerebral blood flow in connection to neural activity and the interplay between neurons, astrocytes and blood vessels. Constant delivery of glucose and oxygen for energy metabolism is vital for brain function, and the physiological basis of neural activity can be assessed through measurements of cerebral blood flow and consumption of glucose and oxygen.... This book presents the complex physiological and neurochemical processes of neural metabolism and function in response to various physiological conditions and pharmacological stimulations. Neurochemical detection technologies and quantitative aspects of monitoring cerebral energy substrates and other metabolites in the living brain are described under the “Cerebral metabolism of antioxidants, osmolytes and others in vivo” section. Altogether, the advent of new in vivo tools has transformed neuroscience and neurobiology research, and demands interdisciplinary approaches as each technology could only approximate a very small fraction of the true complexity of the underlying biological processes. However, translational values of the emerging in vivo methods to the application of preclinical to clinical studies cannot be emphasized enough. Thus, it is our hope that advances in our understanding of biochemical, molecular, functional and physiological processes of the brain could eventually help people with neurological problems, which are still dominated by the unknowns.” -- In-Young Choi and Rolf Gruetter

Glial-Neuronal Signaling in Neuroendocrine Systems

Author : Jeffrey G. Tasker
Publisher : Springer Nature
ISBN 13 : 3030623831
Total Pages : 324 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Glial-Neuronal Signaling in Neuroendocrine Systems by : Jeffrey G. Tasker

Download or read book Glial-Neuronal Signaling in Neuroendocrine Systems written by Jeffrey G. Tasker and published by Springer Nature. This book was released on 2021-04-01 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today. Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication. Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems. This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

The Orexin System. Basic Science and Role in Sleep Pathology

Author : M.A. Steiner
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318068446
Total Pages : 165 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis The Orexin System. Basic Science and Role in Sleep Pathology by : M.A. Steiner

Download or read book The Orexin System. Basic Science and Role in Sleep Pathology written by M.A. Steiner and published by Karger Medical and Scientific Publishers. This book was released on 2021-05-28 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

Human Metabolism

Author : Keith N. Frayn
Publisher : John Wiley & Sons
ISBN 13 : 1119331447
Total Pages : 392 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Human Metabolism by : Keith N. Frayn

Download or read book Human Metabolism written by Keith N. Frayn and published by John Wiley & Sons. This book was released on 2019-03-13 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: The updated bestselling guide to human metabolism and metabolic regulation The revised and comprehensively updated new edition of Human Metabolism (formerly Metabolic Regulation – A Human Perspective) offers a current and integrated review of metabolism and metabolic regulation. The authors explain difficult concepts in clear and concise terms in order to provide an accessible and essential guide to the topic. This comprehensive text covers a wide range of topics such as energy balance, body weight regulation, exercise, and how the body copes with extreme situations, and illustrates how metabolic regulation allows the human body to adapt to many different conditions. This fourth edition has been revised with a new full colour text design and helpful illustrations that illuminate the regulatory mechanisms by which all cells control the metabolic processes necessary for life. The text includes chapter summaries and additional explanatory text that help to clarify the information presented. In addition, the newly revised edition includes more content on metabolic pathways and metabolic diseases. This important resource: Is a valuable tool for scientists, practitioners and students across a broad range of health sciences including medicine, biochemistry, nutrition, dietetics, sports science and nursing Includes a full colour text filled with illustrations and additional diagrams to aid understanding Offers a companion website with additional learning and teaching resources. Written for students of medicine, biochemistry, nutrition, dietetics, sports science and nursing, Human Metabolism has been revised and updated to provide a comprehensive review of metabolism and metabolic regulation.

How Gut and Brain Control Metabolism

Author : P.J.D. Delhanty
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318026395
Total Pages : 204 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis How Gut and Brain Control Metabolism by : P.J.D. Delhanty

Download or read book How Gut and Brain Control Metabolism written by P.J.D. Delhanty and published by Karger Medical and Scientific Publishers. This book was released on 2014-04-10 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is an epidemic problem not limited to Western society, but also in emerging industrial nations with large populations, especially in Asia. The connection between the gut and the brain is probably one of the most promising therapeutic targets for the treatment of obesity and metabolic syndrome. This book brings together reviews on the current understanding of how the gut and brain communicate in the regulation of metabolism. Individual chapters explore novel aspects of this interaction. A comprehensive update on the roles of smell and taste, the gut microbiome, and novel gut-derived neuropeptides in regulating metabolism via the brain is offered. Furthermore, the regulation of insulin sensitivity in the brain is discussed in detail. Providing an overview of the most recent findings, 'How Gut and Brain Control Metabolism' could spark in the reader new ideas or approaches, thus leading to much-needed new medical treatments. Physicians with an involvement in the treatment of metabolic disease and scientists performing research in the fields of nutrition and obesity will find this book a valuable addition to their bookshelves.

Cerebral Metabolism and Neural Function

Author : Janet V. Passonneau
Publisher :
ISBN 13 :
Total Pages : 440 pages
Book Rating : 4.3/5 (129 download)

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Book Synopsis Cerebral Metabolism and Neural Function by : Janet V. Passonneau

Download or read book Cerebral Metabolism and Neural Function written by Janet V. Passonneau and published by . This book was released on 1980 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Obesity and Diabetes Mellitus

Author : E. I. Sokolov
Publisher : CRC Press
ISBN 13 : 1000109755
Total Pages : 334 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Obesity and Diabetes Mellitus by : E. I. Sokolov

Download or read book Obesity and Diabetes Mellitus written by E. I. Sokolov and published by CRC Press. This book was released on 2020-08-13 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the result of the study of metabolic and hormonal disorders in patients suffering obesity and diabetes mellitus, focusing on mechanisms of formation of atherosclerotic changes in the myocardium and vessels in diabetes mellitus patient.

Exogenous and Endogenous Influences on Metabolic and Neural Control of Respiration, Feeding, Activity and Energy Supply in Muscles, Ion- and Osmoregulation, Reproduction, Perception and Orientation: Abstracts

Download Exogenous and Endogenous Influences on Metabolic and Neural Control of Respiration, Feeding, Activity and Energy Supply in Muscles, Ion- and Osmoregulation, Reproduction, Perception and Orientation: Abstracts PDF Online Free

Author : European Society for Comparative Physiology and Biochemistry. Congress
Publisher : Pergamon
ISBN 13 : 9780080288451
Total Pages : 260 pages
Book Rating : 4.2/5 (884 download)

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Book Synopsis Exogenous and Endogenous Influences on Metabolic and Neural Control of Respiration, Feeding, Activity and Energy Supply in Muscles, Ion- and Osmoregulation, Reproduction, Perception and Orientation: Abstracts by : European Society for Comparative Physiology and Biochemistry. Congress

Brain Energy Metabolism

Author : Johannes Hirrlinger
Publisher : Humana Press
ISBN 13 : 9781493910588
Total Pages : 0 pages
Book Rating : 4.9/5 (15 download)

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Book Synopsis Brain Energy Metabolism by : Johannes Hirrlinger

Download or read book Brain Energy Metabolism written by Johannes Hirrlinger and published by Humana Press. This book was released on 2014-09-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Energy Metabolism addresses its challenging subject by presenting diverse technologies allowing for the investigation of brain energy metabolism on different levels of complexity. Model systems are discussed, starting from the reductionist approach like primary cell cultures which allow assessing of the properties and functions of a single brain cell type with many different types of analysis, however, at the expense of neglecting the interaction between cell types in the brain. On the other end, analysis in animals and humans in vivo is discussed, maintaining the full complexity of the tissue and the organism but making high demands on the methods of analysis. Written for the popular Neuromethods series, chapters include the kind of detailed description and key implementation advice that aims to support reproducible results in the lab. Meticulous and authoritative, Brain Energy Metabolism provides an ideal guide for researchers interested in brain energy metabolism with the hope of stimulating more research in this exciting and very important field.

Neural and Metabolic Control of Macronutrient Intake

Author : Hans-Rudolf Berthoud
Publisher : CRC Press
ISBN 13 : 9780367399351
Total Pages : 528 pages
Book Rating : 4.3/5 (993 download)

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Book Synopsis Neural and Metabolic Control of Macronutrient Intake by : Hans-Rudolf Berthoud

Download or read book Neural and Metabolic Control of Macronutrient Intake written by Hans-Rudolf Berthoud and published by CRC Press. This book was released on 2019-10-07 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: When an excessive proportion of the human energy requirement is derived from fat, the likelihood of obesity increases. Any such individual is at risk for diabetes and cardiovascular disease- grave and costly health hazards. The selective control of fat ingestion is a promising solution to these concerns. Existing data suggests that macronutrient intake can be manipulated. Further research is working to create pharmacological tools that will suppress fat consumption. It will also be possible to fight obesity, heart disease and diabetes. Neural and Metabolic Control of Macronutrient Intake systematically discusses the known physiological mechanisms involved in macronutrientselection, including their molecular, genetic and neurochemical aspects. The book is also a critical review of the hypothesis that ingestion of the three nutrients is regulated by separate neural control mechanisms, leaving open the possibility that strategies could be devised to intervene in bodily control systems and alter the proportion of fat in the diet. This reference provides three types of information: First, the basic background of the biochemical and physiological systems as they relate to macronutrient selection. Second, opinions and data concerning to what degree animals and humans show evidence of macronutrient selection. And, third, evidence about how the central nervous system might be involved in the choices animals make among macronutrients.

Metabolic Regulation

Author : Keith N. Frayn
Publisher : John Wiley & Sons
ISBN 13 : 140514761X
Total Pages : 352 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Metabolic Regulation by : Keith N. Frayn

Download or read book Metabolic Regulation written by Keith N. Frayn and published by John Wiley & Sons. This book was released on 2009-02-11 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metabolic Regulation looks in detail at how molecules, cells and tissues operate collectively in human health and disease, using an approach that has become known as ‘integrative physiology’. Since the publication of the first edition of this extremely well received book, the understanding of how metabolism is regulated has developed substantially in several ways, for example with the discovery of the hormone leptin, and also in the continuing advances in the understanding of gene expression. Full details of these and other new advances are included in this fully updated edition. Carefully laid out with relevant and clearly explained examples, and containing much new material, this new edition covers in an integrated way: concepts and mechanisms, digestion and intestinal absorption, organs and tissues, endocrine organs and hormones, the integration of carbohydrate, fat and protein metabolism, the nervous system and metabolism, lipoprotein metabolism, diabetes mellitus, energy balance and body weight regulation and how the body copes with some extreme situations. The author, Keith Frayn, who has many years’ experience teaching and researching in this subject, has written a book of great clarity, which is an extremely valuable tool for scientists, practitioners and students working and studying across a broad range of allied health sciences including nutrition, dietetics, sports science and nursing. Students of medicine, physiology, biochemistry and biological sciences will also find much of great use and interest in this book. All libraries in research establishments, universities and medical schools where these subjects are studied and taught should have multiple copies of this excellent book on their shelves. Keith Frayn is Professor of Human Metabolism at the University of Oxford, UK.Reviews of the First Edition ‘This is an excellent textbook’: Trends in Endocrinology and Metabolism ‘The coverage is excellent for students following courses such as nutrition and human biology’:Biologist ‘This book is ideal for medical students’:Australian Society for Biochemistry and Molecular Biology

Fuel Homeostasis and the Nervous System

Author : Mladen Vranic
Publisher : Springer Science & Business Media
ISBN 13 : 1468459317
Total Pages : 276 pages
Book Rating : 4.4/5 (684 download)

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Book Synopsis Fuel Homeostasis and the Nervous System by : Mladen Vranic

Download or read book Fuel Homeostasis and the Nervous System written by Mladen Vranic and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book has a dual purpose, to review in depth the control of fuel homeostasis in the brain and the role of the nervous system in the control of fuel deposition in the body. From the methodological point of view the emphasis is on the application of advanced technologies to assess fuel transport and brain metabolism, the role of peptides in the neuroendocrine system and the response of the brain to hypoglycemia. These technologies include positron emmission tomography, nuclear magnetic resonance, immunocytochemistry, molecular biology, autoradiography. To study fuel homeostasis in the body advanced tracer methods that include modelling are set out. From the pathophysiological point of view the emphasis is on abnormalities in stress, brain metabolism in diabetes, eating and degenerative disorders. This book contains contributions from endocrinologists, physiologists, neurologists, psychoneuroendocrinOlogists, biophysicists, biochemists and experts in nutrition. This authorship represents a unique diversity of researchers who, for the first time, cover comprehensively the interaction between the nervous system and fuel homeostasis, both in health and disease. We hope this book will be an important source of information for both researchers and practicing clinicians. Mladen Vranic Suad Efendic Charles Hollenberg v ACKNOWLEDGEMENTS The Symposium from which this volume arose (University of Toronto, June 27-28, 1990) was the first Toronto-Stockholm symposium on Perspectives in Diabetes Research. These Symposia are organized triennially by the Banting and Best Diabetes Centre, University of Toronto and the Department of Endocrinology, Karolinska Institute, Stockholm.

Exogenous and Endogenous Influences on Metabolic and Neural Control of Respiration, Feeding, Activity and Energy Supply in Muscles, Ion- and Osmoregulation, Reproduction, Perception and Orientation: Invited lectures

Author : European Society for Comparative Physiology and Biochemistry. Congress
Publisher : Pergamon
ISBN 13 :
Total Pages : 442 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Exogenous and Endogenous Influences on Metabolic and Neural Control of Respiration, Feeding, Activity and Energy Supply in Muscles, Ion- and Osmoregulation, Reproduction, Perception and Orientation: Invited lectures by : European Society for Comparative Physiology and Biochemistry. Congress

Download or read book Exogenous and Endogenous Influences on Metabolic and Neural Control of Respiration, Feeding, Activity and Energy Supply in Muscles, Ion- and Osmoregulation, Reproduction, Perception and Orientation: Invited lectures written by European Society for Comparative Physiology and Biochemistry. Congress and published by Pergamon. This book was released on 1982 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exogenous and Endogenous Influences on Metabolic and Neural Control, Volume 1: Invited Lectures covers the proceedings of the Third Congress of the European Society for Comparative Physiology and Biochemistry. The book presents 35 papers that cover various aspects in the control of physiological activities in animals. The text first details the origin of physiology and comparative physiology. Next, the book covers papers that deal with different physiological systems, which include feeding, respiration, reproduction, osmoregulation, and perception. The text will be of great use to students, re ...

Brain Iron Metabolism and CNS Diseases

Author : Yan-Zhong Chang
Publisher : Springer Nature
ISBN 13 : 9811395896
Total Pages : 194 pages
Book Rating : 4.8/5 (113 download)

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Book Synopsis Brain Iron Metabolism and CNS Diseases by : Yan-Zhong Chang

Download or read book Brain Iron Metabolism and CNS Diseases written by Yan-Zhong Chang and published by Springer Nature. This book was released on 2019-08-27 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on advances in our understanding of the regulatory mechanisms of brain iron uptake, iron homeostasis and iron metabolism in the pathophysiology and pharmacology of CNS disease models. Dysregulation of brain iron homeostasis can lead to severe pathological changes in the neural system. Iron deficiency can slow down the development of the neural system and cause language and motion disorders, while iron overload is closely related to neurodegenerative diseases. Although some current books include chapters on iron metabolism and certain neurodegenerative diseases, this is the first systematic summary of the latest discoveries regarding brain iron metabolism and CNS diseases. By providing novel and thought-provoking insights into the mechanisms and physiological significance of brain iron metabolism and related diseases, the book stimulates further new research directions. It helps graduate students and researchers gain an overall picture of brain iron metabolism and the pathogenesis of neurodegenerative diseases, and also offers pharmaceutical companies inspiration for new treatment strategies for CNS diseases.