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Nano Medicine And Nano Safety
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Book Synopsis Nano Medicine and Nano Safety by : Malay K. Das
Download or read book Nano Medicine and Nano Safety written by Malay K. Das and published by Springer Nature. This book was released on 2020-12-09 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the application of Nanobiotechnology in the development of Nanomedicine, while also discussing the latest trends and challenges in the clinical translation of Nanomedicine. Nanomedicine refers to the application of Nanotechnology to medicine and holds tremendous potential for achieving improved efficiency, bioavailability, dose response, personalized medicine and enhanced safety as compared to conventional medicines. The book first introduces readers to the basic concepts of Nanomedicine, and to technological advances in and applications of Nanotechnology in treatment, diagnosis, monitoring, and drug delivery. In turn, it reviews the current status of multi-functionalization strategies for using Nanoparticles in the targeted delivery of therapeutic agents. The book’s third and final section focuses on the regulatory and safety challenges posed by Nanomedicine, including industry and regulatory agencies’ efforts to address them.
Book Synopsis Nano-Safety by : Dominick E. Fazarro
Download or read book Nano-Safety written by Dominick E. Fazarro and published by Walter de Gruyter GmbH & Co KG. This book was released on 2023-12-31 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology safety is the practice of handling engineered nanomaterials in production and manufacturing. Good practice consists of understanding and interpreting Material Safety Data Sheets, behaving safely when working with yet unknown nanomaterials, understanding health effects, and proactively creating safety measures against potential hazards. This book addresses nanotechnology risk management.
Book Synopsis Nanotechnology in Medicine by : Mahendra Rai
Download or read book Nanotechnology in Medicine written by Mahendra Rai and published by John Wiley & Sons. This book was released on 2021-10-25 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: NANOTECHNOLOGY IN MEDICINE Discover thorough insights into the toxicology of nanomaterials used in medicine In Nanotechnology in Medicine: Toxicity and Safety, an expert team of nanotechnologists delivers a robust and up-to-date review of current and future applications of nanotechnology in medicine with a special focus on neurodegenerative diseases, cancer, diagnostics, nano-nutraceuticals, dermatology, and gene therapy. The editors offer resources that address nanomaterial safety, which tends to be the greatest hurdle to obtaining the benefits of nanomedicine in healthcare. The book is a one-stop resource for recent and comprehensive information on the toxico logical and safety aspects of nanotechnology used in human health and medicine. It provides readers with cutting-edge techniques for delivering therapeutic agents into targeted cellular compartments, cells, tissues, and organs by using nanoparticulate carriers. The book also offers methodological considerations for toxicity, safety, and risk assessment. Nanotechnology in Medicine: Toxicity and Safety also provides readers with: A thorough introduction to the nanotoxicological aspects of nanomedicine, including translational nanomedicine and nanomedicine personalization Comprehensive introductions to nanoparticle toxicity and safety, including selenium nanoparticles and metallic nanoparticles Practical discussions of nanotoxicology and drug delivery, including gene delivery using nanocarriers and the use of nanomaterials for ocular delivery applications In-depth examinations of nanotechnology ethics and the regulatory framework of nanotechnology and medicine Perfect for researchers, post-doctoral candidates, and specialists in the fields of nanotechnology, nanomaterials, and nanocarriers, Nanotechnology in Medicine: Toxicity and Safety will also prove to be an indispensable part of the libraries of nanoengineering, nanomedicine, and biopharmaceutical professionals and nanobiotechnologists.
Book Synopsis Handbook of Safety Assessment of Nanomaterials by : Bengt Fadeel
Download or read book Handbook of Safety Assessment of Nanomaterials written by Bengt Fadeel and published by CRC Press. This book was released on 2014-12-10 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapidly evolving field of nanomedicine refers to the clinical application of nanotechnologies. However, as with all new technologies, there are ethical, safety, and regulatory issues. This handbook, written by leading international experts, provides a meticulous overview of the state of the art of safety assessment of nanomaterials (nanotoxicology) in the context of their application in nanomedicine. The volume includes a historical perspective on the development of nanomedicine and its regulation, and a personal view of the future of (nano)medicine by Patrick Hunziker, president of the European Society of Nanomedicine. Ethical considerations in relation to nanomedicine are discussed. There are a series of chapters on organ-specific toxicities of nanomaterials, including pulmonary and cardiovascular toxicity, neurotoxicity, dermatotoxicity, and reproductive toxicity, as well as a discussion on immunotoxicity and genotoxicity. The importance of a thorough characterization of physicochemical properties of nanomaterials is emphasized. The handbook also contains a critical discussion on the applicability of in vitro versus in vivo methods and models for nanosafety assessment, along with an introduction to mathematical modeling approaches with a view to a predictive toxicology of nanomaterials. The overall aim is to provide a comprehensive, science-based framework for safety assessment of current and future nanomedicines.
Author :Stergios Logothetidis Publisher :Springer Science & Business Media ISBN 13 :3642241816 Total Pages :140 pages Book Rating :4.6/5 (422 download)
Book Synopsis Nanomedicine and Nanobiotechnology by : Stergios Logothetidis
Download or read book Nanomedicine and Nanobiotechnology written by Stergios Logothetidis and published by Springer Science & Business Media. This book was released on 2012-01-15 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the laboratory, scientific and clinical aspects of nanomaterials used for medical applications in the fields of regenerative medicine, dentistry and pharmacy. It gives a broad overview on the in vitro compatibility assessment of nanostructured materials implemented in the medical field by the combination of classical biological protocols and advanced non-destructive nano-precision techniques with special emphasis on the topographical, surface energy, optical and electrical properties. Materials in the physical form of nanoparticles, nanotubes, and thin films are addressed in terms of their toxicity. The different pillars of the Nanomedicine field are also highlighted. The book takes an interdisciplinary approach of medicine, biology, pharmacy, physics, chemistry, engineering, nanotechnology and materials science. The international group of authors specifically chosen for their distinguished expertise belong to the academic and industrial world in order to provide a broader perspective. It appeals to researchers and graduate students.
Book Synopsis Nano-Safety by : Dominick E. Fazarro
Download or read book Nano-Safety written by Dominick E. Fazarro and published by Walter de Gruyter GmbH & Co KG. This book was released on 2017-09-25 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology safety is the practice of handling engineered nanomaterials in production and manufacturing. Good practice consists of understanding and interpreting Material Safety Data Sheets, behaving safely when working with yet unknown nanomaterials, understanding health effects, and proactively creating safety measures against potential hazards. This book introduces nanotechnology risk management to readers from academia and industry.
Book Synopsis Medical Nanotechnology and Nanomedicine by : Harry F. Tibbals
Download or read book Medical Nanotechnology and Nanomedicine written by Harry F. Tibbals and published by CRC Press. This book was released on 2010-09-29 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Considering the fluid nature of nano breakthroughs—and the delicate balance between benefits and consequences as they apply to medicine—readers at all levels require a practical, understandable base of information about these developments to take greatest advantage of them. Medical Nanotechnology and Nanomedicine meets that need by introducing non-experts to nanomedicine and its evolving organizational infrastructure. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects—an ideal foundation upon which to plan and make decisions. Covers the use of nanotechnology in medical applications including imaging, diagnosis and monitoring, drug delivery systems, surgery, tissue regeneration, and prosthetics Part of the Perspectives in Nanotechnology series—which contains broader coverage of the societal implications of nanotechnology—this book can be used as a standalone reference. Organized by historical perspective, current status, and future prospects, this powerful book: Explores background, definitions and terms, and recent trends and forces in nanomedicine Surveys the landscape of nanomedicine in government, academia, and the private sector Reviews projected future directions, capabilities, sustainability, and equity of nanomedicine, and choices to be made regarding its use Includes graphical illustrations, references, and keywords to reinforce concepts and aid further research In its assessment of alternative and sometimes conflicting concepts proposed for the application of nanotechnology to medicine, this book surveys major initiatives and the work of leading labs and innovators. It uses informative examples and case summaries to illustrate proven accomplishments and imagined possibilities in research and development.
Book Synopsis Nanotoxicology by : Nancy A. Monteiro-Riviere
Download or read book Nanotoxicology written by Nancy A. Monteiro-Riviere and published by CRC Press. This book was released on 2014-03-03 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This includes new improved characterization endpoints, screening, and detection methods for in vitro and in vivo toxicity testing. These tools also contribute greatly to nanosafety research applied to nanomedicines. Topics include The impacts of nanotechnology on biomedicine, including functionalization for tissue-specific targeting, the biointeractions of multifunctional nanoparticle-based therapy, and the ability to control specific physicochemical properties of nanoparticles The requirements for proper detection, measurement, and assessment both for workplace exposure and in consumer products—with a focus on potential health and safety implications Predictive modeling, using quantitative nanostructure activity relationships to predict the pharmacokinetics and biodistribution of nanomaterials in the body Specific methodologies, imaging, and techniques to assess nanomaterials from the manufacturing process to nanomedicine applications Tools for assessing nanoparticle toxicity and the limitations of detection methods for assessing toxicity in both in vivo and in vitro systems and at the single cell and tissue levels Toxicity of nanomaterials to specific organ systems, cell–based targeting to tumors, and other biomedical applications The difficulty of conducting risk assessments and the need for addressing knowledge gaps, especially with long-term studies A roadmap for future research The development of nanotechnology-based products must be complemented with appropriate validated methods to assess, monitor, manage, and reduce the potential risks of ENM to human health and the environment. This volume provides a cogent survey of advances in this area by a well-respected and diverse group of international scientists.
Book Synopsis Nanotechnology Safety by : Ramazan Asmatulu
Download or read book Nanotechnology Safety written by Ramazan Asmatulu and published by Newnes. This book was released on 2013-06-12 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is a new and emerging discipline that is multidisciplinary and interdisciplinary. The usage of nanosystems, nanomaterials, nano-devices, etc. permeates all aspects of society. Cancer targeting and curing nanosystems are being introduced into the biomedical and pharmaceutical industries; so are lightweight energy absorbing or blast-proof nanohybrid material in the aerospace, automotive and marine industries and high-efficiency energy harvesting nanomaterials, etc. Society has a vested interest in knowing how these new materials, devices and systems are changing the economy and similar landscapes. The book outlines the regulatory and environmental issues related to nanotechnology per industry, offers guidelines in assessing the risks and discusses the legal and socioeconomical issues involved. Case studies will be utilized to provide examples of the positive and negative impacts of nanotechnology. Provides an overview and the basis for understanding the critical importance of the reactivity and efficacy of nanomaterials and the emerging role of nanotechnology in society Explains the fundamentals, ethics, regulatory and environmental issues of nanosafety and how they shape the emerging nanotechnology industry and markets and includes extensive lists of glossary terms, terminologies and concepts needed for Material Data Safety Sheets Discusses the relevance and specificity of nanosafety issues per industry and includes discussions on the "Homeland Security and Infrastructure Industries" of interest to society in general Includes nanotechnology risk assessment and delineates and quantifies the risk assessment process for nanotechnology safety of paramount importance to most industries and systems Outlines the legal and intellectual property ramifications of nanotechnology and its impact on productivity and society
Book Synopsis Safety of Nanoparticles by : Thomas J. Webster
Download or read book Safety of Nanoparticles written by Thomas J. Webster and published by Springer Science & Business Media. This book was released on 2008-11-18 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first (if not the first) detailed views of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.
Book Synopsis Advances and Challenges in Nanomedicine by : Susan Hua
Download or read book Advances and Challenges in Nanomedicine written by Susan Hua and published by Frontiers Media SA. This book was released on 2019-02-28 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology is a multidisciplinary field that is revolutionizing the way we detect and treat damage to the human body. Nanomedicine applies nanotechnology to highly specific medical interventions for the prevention, diagnosis, and treatment of diseases. They are increasingly being used to overcome biological barriers in the body to improve the way we deliver compounds to specific tissues and organs. In particular, nanomedicines have been shown to be beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake, and improving biodistribution of compounds to target sites in vivo. Nanomedicines have demonstrated significant therapeutic advantages for a multitude of biomedical applications, however the clinical translation of these nanotechnology platforms has not progressed as quickly as the plethora of positive results would have suggested. Understanding the advances in nanomedicine to date and the challenges that still need to be overcome, will allow future research to improve on existing platforms and to address the current translational and regulatory limitations. This eBook “Advances and Challenges in Nanomedicine” has brought together experts in the fields of nanomedicine, nanotechnology, nanotoxicology, pharmaceutics, manufacturing, and translation to discuss the application of nanotechnology to drug delivery. This information is presented as original research, opinion, perspective, and review articles. The goal of this eBook is to generate collaborative discussion on the current status, general trends, challenges, strategies, and future direction of pharmaceutical nanotechnology, as well as highlight current and emerging nanoparticulate platforms with potential medical applications.
Download or read book Nanotechnology written by Jo Anne Shatkin and published by CRC Press. This book was released on 2017-12-19 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Should you adopt nanotechnology? If you have already adopted it, what do you need to know? What are the risks? Nanomaterials and nanotechnologies are revolutionizing the ways we treat disease, produce energy, manufacture products, and attend to our daily wants and needs. To continue to capture the promise of these transformative products, however, we need to ask critical questions about the broader impacts of nanotechnology on society and the environment. Exploring these questions, the second edition of Nanotechnology: Health and Environmental Risks gives you the latest tools to understand the risks of nanotechnology and make better decisions about using it. Examining the state of the science, the book discusses what is known, and what still needs to be understood, about nanotechnology risk. It looks at the uses of nanotechnology for energy, industry, medicine, technology, and consumer applications and explains how to determine whether there is risk—even when there is little reliable evidence—and how to manage it. Contributors cover a wide range of topics, including: Current concerns, among them perceived risks and the challenges of evaluating emerging technology A historical perspective on product safety and chemicals policy The importance of being proactive about identifying and managing health and environmental risks during product development How the concepts of sustainability and life cycle assessment can guide nanotechnology product development Methods for evaluating nanotechnology risks, including screening approaches and research How to manage risk when working with nanoscale materials at the research stage and in occupational environments What international organizations are doing to address risk issues How risk assessment can inform environmental decision making Written in easy-to-understand language, without sacrificing complexity or scientific accuracy, this book offers a wide-angle view of nanotechnology and risk. Supplying cutting-edge approaches and insight, it explains what types of risks could exist and what you can do to address them. What’s New in This Edition Updates throughout, reflecting advances in the field, new literature, and policy developments A new chapter on nanotechnology risk communication, including insights into risk perceptions and the mental models people use to evaluate technological risks An emphasis on developing nanotechnology products that are sustainable in the long term Advances in the understanding of nanomaterials toxicity Cutting-edge research on occupational exposure to nanoparticles Changes in the international landscape of organizations working on the environmental, health, and safety aspects of nanotechnologies
Book Synopsis Health and Environmental Safety of Nanomaterials by : James Njuguna
Download or read book Health and Environmental Safety of Nanomaterials written by James Njuguna and published by Elsevier. This book was released on 2014-02-15 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health and Environmental Safety of Nanomaterials addresses concerns about the impact of nanomaterials on the environment and human health, and examines the safety of specific nanomaterials. Understanding the unique chemical and physical properties of nanostructures has led to many developments in the applications of nanocomposite materials. While these materials have applications in a huge range of areas, their potential for toxicity must be thoroughly understood. Part one introduces the properties of nanomaterials, nanofillers, and nanocomposites, and questions whether they are more toxic than their bulk counterparts. Part two looks at the release and exposure of nanomaterials. The text covers sampling techniques and data analysis methods used to assess nanoparticle exposure, as well as protocols for testing the safety of polymer nanocomposites. It explains characterization techniques of airborne nanoparticles and life cycle assessment of engineered nanomaterials. Part three focuses on the safety of certain nanomaterials, including nanolayered silicates, carbon nanotubes, and metal oxides. In particular, it explores the potential ecotoxicological hazards associated with the different structures of carbon nanotubes and the safe recycling of inorganic and carbon nanoparticles. The final two chapters address the risks of nanomaterials in fire conditions: their thermal degradation, flammability, and toxicity in different fire scenarios. This is a scientific guide with technical background for professionals using nanomaterials in industry, scientists, academicians, research scholars, and polymer engineers. It also offers a deep understanding of the subject for undergraduate and postgraduate students. Introduces the properties of nanomaterials, nanofillers, and nanocomposites, and questions whether they are more toxic than their bulk counterparts Covers sampling techniques and data analysis methods used to assess nanoparticle exposure, as well as protocols for testing the safety of polymer nanocomposites Explores the potential ecotoxicological hazards associated with the different structures of carbon nanotubes and the safe recycling of inorganic and carbon nanoparticles
Book Synopsis Handbook of Clinical Nanomedicine by : Raj Bawa
Download or read book Handbook of Clinical Nanomedicine written by Raj Bawa and published by CRC Press. This book was released on 2016-04-27 with total page 1502 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique handbook (60 chapters) examines the entire "product life cycle," from the creation of nanomedical products to their final market introduction. While focusing on critical issues relevant to nanoproduct development and translational activities, it tackles topics such as regulatory science, patent law, FDA law, ethics, personalized medicine, risk analysis, toxicology, nano-characterization and commercialization activities. A separate section provides fascinating perspectives and editorials from leading experts in this complex interdisciplinary field.
Book Synopsis Interaction of Nanomaterials With the Immune System: Role in Nanosafety and Nanomedicine by : Paola Italiani
Download or read book Interaction of Nanomaterials With the Immune System: Role in Nanosafety and Nanomedicine written by Paola Italiani and published by Frontiers Media SA. This book was released on 2018-04-10 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: The immune system has the double role of maintaining tissue integrity and homeostasis and of protecting the organism from possible dangers, from invading pathogens to environmentally-borne dangerous chemicals. New chemicals recognisable by the immune system are engineered nanomaterials/ nanoparticles, new agents in our environment that are becoming common due to their presence in many products, from constructions and building material (e.g., solar cells, pigments and paints, tilesand masonry materials) to daily products (e.g., food packaging, cosmetics, and cigarettes). Human beings can be accidentally exposed to engineered nanomaterials when these are released from products containing them or during production in workplaces. Furthermore, intentional exposure occurs in medicine, as engineered nanoparticles are used as tools for improving delivery of drugs and vaccines, vaccine adjuvants and contrast agents in therapeutic, preventive and diagnostic strategies. Nanoparticles that come in contact with the immune system after unintentional exposure need to be eliminated from the organism as they represent a potential threat. In this case, however, due to their peculiar characteristics of size, shape, surface charge and persistence, nanoparticles may elicit undesirable reactions and have detrimental effects on the immune system, such as cytotoxicity, inflammation, anaphylaxis, immunosuppression. Conversely, nanomedicines need to escape immune recognition/elimination and must persist in the organism long enough for reaching their target and exerting their beneficial effects. Immune cells and molecules at the body surface (airway and digestive mucosae, skin) are the first that come in contact with nanomaterials upon accidental exposure, while immune effectors in blood are those that more easily come in contact with nanomedical products. Thus, evaluating the interaction of the immune system with nanoparticles/nanomaterials is a topic of key importance both in nanotoxicology and in nanomedicine. Immuno-nanosafety studies consider both accidental exposure to nanoparticles, which may occur by skin contact, ingestion or inhalation (at doses and with a frequency that are not known), and medical exposure, which takes place with a defined administration schedule (route, dose, frequency). Many studies focus on the interaction between the immune system and nanoparticles that, for medical purposes, have been specifically modified to stimulate immunity or to avoid immune recognition, as in the case of vaccine carriers/adjuvants or drug delivery systems, respectively. The aims of this Research Topic is to provide an overview of recent strategies: 1.for assessing the immunosafety of engineered nanomaterials/nanoparticles, in particular in terms of activation of inflammatory responses, such as complement activation and allergic reactions, based on the nanomaterial intrinsic characteristics and on the possible carry-over of bioactive contaminants such as LPS. Production of new nanoparticles taking into account their effects on immune responses, in order to avoid undesirable effects on one hand, and to design particles with desirable effects for medical applications on the other hand; 2.for designing more effective nanomedicines by either avoiding or exploiting their interaction with the immune systems, with particular focus on cancer diagnosis and therapy, and vaccination. This collection of articles gives a comprehensive view of the state-of-the-art of the interaction of nanoparticles with the immune system from the two perspectives of safety and medical use, and aims at providing immunologists with the relevant knowledge for designing improved strategies for immunologically safe nanomaterial applications.
Book Synopsis Nanotoxicology by : Hemant Kumar Daima
Download or read book Nanotoxicology written by Hemant Kumar Daima and published by CRC Press. This book was released on 2021-07-15 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges. This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment. Key Features: Reveals novel nanoscale approaches, toxicity assessment, and biomedical applications Includes importance of nanotoxicity concepts in developing smart nanomaterials Highlights unique contributions and "A to Z" aspects on the state-of-the-art from global leaders Offers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicines Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Further, this book reports legal, ethical, safety, and regulatory issues associated with nanomaterials, which have often been neglected, if not overlooked in literature and limiting clinical translation at nanoscale level. It will equip readers with cutting-edge knowledge of promising developments in nanomedicine and nanotoxicology, along with potential future prospects.
Book Synopsis Safety of Nanoparticles by : Thomas J. Webster
Download or read book Safety of Nanoparticles written by Thomas J. Webster and published by Springer. This book was released on 2008-12-02 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: In spite of the potential use of nanomaterials as tissue engineering devices, implants, biosensors, drug delivery devices, etc., there has yet to be a compilation of the risks associated with the in vivo use of nanomaterials. There are numerous and well-known risks because of the size of nanoparticles. For example, nanoparticles can cross cell membranes and enter the cytoplasm undetected. The aim of this book is to provide one of the first (if not the first) detailed views of how cells and tissues in the body deal with nanoparticles. This is important not only for implantable devices, but also for the manufacturing of nanophase materials when particles can be inhaled or enter the body through the skin. Only by compiling research at the intersection of nanoparticles and biological processes can we determine if nanophase materials are safe to be manufactured, handled, and/or implanted for various medical applications.
