The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine

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Author :
Publisher : Springer
ISBN 13 : 9811053111
Total Pages : 392 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine by : Richard Eugene Frye

Download or read book The Therapeutic Use of N-Acetylcysteine (NAC) in Medicine written by Richard Eugene Frye and published by Springer. This book was released on 2018-09-20 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on the practical use of N-Acetyl-Cysteine (NAC) in medicine, this book provides a comprehensive review of the basic biological and clinical studies documenting its benefits in treating medical disease. NAC is perhaps best known as an antidote for acetaminophen, but its therapeutic effect in a wide range of medical diseases has recently been realized. In addition to its well recognized use in radiological contrast prophylaxis for renal disease and pulmonary disorders, studies have suggested significant promise in psychiatric and neurological disorders such as addiction, Alzheimer’s disease, ataxia, autism, bipolar disorder, depression, epilepsy, neuropathy, obsessive-compulsive disorder, schizophrenia, traumatic brain injury and trichotillomania in addition to promising studies in audiology, cardiology, exercise physiology, gastroenterology, hematology, infectious disease, infertility and ophthalmology. Given the promising studies for a wide range of medical conditions, coupled with a excellent safety profile, the potential for NAC in the treatment of human disease appears considerable. Dr Leonore A Herzenberg from Stanford University, a pioneer of redox physiology and the use of NAC, provides a succinct history of the development of the therapeutic use of NAC for medical disease. This is followed by a series of basic science chapters outlining the role of NAC in important physiological processes, including modulation of dopamine and glutamate neurotransmitter systems, redox and mitochondrial metabolism, apoptosis and inflammation. The last section of the book is dedicated to clinically oriented chapters that comprehensively review the literature on medical disorders in which NAC has been found to be effective, including toxicity and cardiovascular, gastrointestinal, neurological, psychiatric, pulmonary and renal disorders. Each chapter reviews the theoretical biological mechanisms of NAC for the specific diseases reviewed, rates the clinical studies using a standardized criteria in order to provide an objective level of evidence and grade of recommendation for the use of NAC for specific medical conditions and outlines the ongoing clinical trials examining NAC for the treatment of specific diseases. Final chapters review the clinical evidence verifying that specific theoretical biological mechanisms are actually being targeted by NAC in medical disease. Studies on the pharmacology, formulation and potential adverse effects of NAC are also reviewed. A final chapter synthesizes the clinical studies to suggest that the effectiveness of NAC may signal a new basic physiological disorder, glutathione deficiency, which may be an important pathophysiological mechanism of many diseases.

Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals

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Author :
Publisher : National Academies Press
ISBN 13 : 030907553X
Total Pages : 225 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals by : National Research Council

Download or read book Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals written by National Research Council and published by National Academies Press. This book was released on 2001-06-25 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Standing Operating Procedures for Developing Acute Exposure Guideline Levels for Hazardous Chemicals contains a detailed and comprehensive methodology for developing acute exposure guideline levels (AEGLs) for toxic substances from inhalation exposures. The book provides guidance on what documents and databases to use, toxicity endpoints that need to be evaluated, dosimetry corrections from animal to human exposures, selection of appropriate uncertainty factors to address the variability between animals and humans and within the human population, selection of modifying factors to address data deficiencies, time scaling, and quantitative cancer risk assessment. It also contains an example of a summary of a technical support document and an example of AEGL derivation. This book will be useful to persons in the derivation of levels from other exposure routesâ€"both oral and dermalâ€"as well as risk assessors in the government, academe, and private industry.

NAC OSCE

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Author :
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781466464162
Total Pages : 0 pages
Book Rating : 4.4/5 (641 download)

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Book Synopsis NAC OSCE by : Canadaprep

Download or read book NAC OSCE written by Canadaprep and published by Createspace Independent Publishing Platform. This book was released on 2011-10-30 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a guide through the steps of the National Association Collaboration (NAC) Objective Structured Clinical Examination (OSCE).

Tiffany Aching Complete 5-Book Collection

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Publisher : HarperCollins
ISBN 13 : 006245742X
Total Pages : 834 pages
Book Rating : 4.0/5 (624 download)

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Book Synopsis Tiffany Aching Complete 5-Book Collection by : Terry Pratchett

Download or read book Tiffany Aching Complete 5-Book Collection written by Terry Pratchett and published by HarperCollins. This book was released on 2015-09-01 with total page 834 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection includes all five Tiffany Aching novels in Terry Pratchett's beloved and bestselling Discworld series, including the final Discworld novel, The Shepherd's Crown. The Wee Free Men: Armed with only a frying pan and her common sense, young witch-to-be Tiffany Aching must defend her home against the monsters of Fairyland. Luckily she has some very unusual help: the local Nac Mac Feegle—aka the Wee Free Men. A Hat Full of Sky: Tiffany Aching is ready to begin her apprenticeship in magic. She expects spells and magic—not chores and ill-tempered nanny goats! Surely there must be more to witchcraft than this! Indeed, there is. . . . Wintersmith: When the Spirit of Winter takes a fancy to Tiffany Aching, he wants her to stay in his gleaming, frozen world. Forever. It will take the young witch's skill and cunning, as well as help from the legendary Granny Weatherwax and the irrepressible Wee Free Men, to survive until Spring. I Shall Wear Midnight: As the witch of the Chalk, Tiffany Aching performs the distinctly unglamorous work of caring for the needy. But someone—or something—is inciting fear, generating dark thoughts and angry murmurs against witches. Tiffany must find the source of unrest and defeat the evil at its root, for if she falls, the whole Chalk falls with her. . . . The Shepherd's Crown: Deep in the Chalk, something is stirring. The owls and the foxes can sense it, and Tiffany Aching feels it in her boots. An old enemy is gathering strength. This is a time of endings and beginnings, old friends and new, a blurring of edges and a shifting of power. Now Tiffany stands between the light and the dark, the good and the bad. There will be a reckoning. . . .

Exodus

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Publisher : B&H Publishing Group
ISBN 13 : 1433672596
Total Pages : 832 pages
Book Rating : 4.4/5 (336 download)

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Book Synopsis Exodus by : Douglas K. Stuart

Download or read book Exodus written by Douglas K. Stuart and published by B&H Publishing Group. This book was released on 2006-06-15 with total page 832 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE NEW AMERICAN COMMENTARY is for the minister or Bible student who wants to understand and expound the Scriptures. Notable features include:* commentary based on THE NEW INTERNATIONAL VERSION;* the NIV text printed in the body of the commentary; * sound scholarly methodology that reflects capable research in the original languages; * interpretation that emphasizes the theological unity of each book and of Scripture as a whole; * readable and applicable exposition.

Network Access Control For Dummies

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Publisher : John Wiley & Sons
ISBN 13 : 0470501340
Total Pages : 340 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Network Access Control For Dummies by : Jay Kelley

Download or read book Network Access Control For Dummies written by Jay Kelley and published by John Wiley & Sons. This book was released on 2009-04-13 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Network access control (NAC) is how you manage network security when your employees, partners, and guests need to access your network using laptops and mobile devices. Network Access Control For Dummies is where you learn how NAC works, how to implement a program, and how to take real-world challenges in stride. You’ll learn how to deploy and maintain NAC in your environment, identify and apply NAC standards, and extend NAC for greater network security. Along the way you’ll become familiar with what NAC is (and what it isn’t) as well as the key business drivers for deploying NAC. Learn the steps of assessing, evaluating, remediating, enforcing, and monitoring your program Understand the essential functions of Authentication, Authorization, and Accounting Decide on the best NAC approach for your organization and which NAC policies are appropriate Discover how to set policies that are enforceable and reasonable enough to be followed, yet still effective Become familiar with the architectures and standards essential to NAC Involve and motivate everyone in the organization whose support is critical to a successful implementation Network Access Control For Dummies shows you the steps for planning your implementation, who should be involved, where enforcement should occur, and much more. When you flip the switch, you’ll know what to expect.

The Bible in a Year Notebook

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Publisher :
ISBN 13 : 9781950784721
Total Pages : pages
Book Rating : 4.7/5 (847 download)

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Book Synopsis The Bible in a Year Notebook by : Ascension

Download or read book The Bible in a Year Notebook written by Ascension and published by . This book was released on 2021-04-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies

Download Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies PDF Online Free

Author :
Publisher : Springer
ISBN 13 : 331928570X
Total Pages : 246 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies by : Afshin Amini

Download or read book Utility of Bromelain and N-Acetylcysteine in Treatment of Peritoneal Dissemination of Gastrointestinal Mucin-Producing Malignancies written by Afshin Amini and published by Springer. This book was released on 2016-03-05 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will describe both growth-inhibitory and mucin-depleting effects of bromelain and N-acetylcysteine, on their own or in combination, in cancer. It will coherently review the pathophysiological aspects of the mucin glycoproteins in malignancies and provide an updated account of the status of bromelain and N-acetylcysteine in cancer therapy. The volume will develop the idea of using these two drugs as a combination formulation for mucin-depleting effects.

1, 2 Samuel

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Publisher : B&H Publishing Group
ISBN 13 : 0805401075
Total Pages : 516 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis 1, 2 Samuel by : Robert D. Bergen

Download or read book 1, 2 Samuel written by Robert D. Bergen and published by B&H Publishing Group. This book was released on 1996 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: One in an ongoing series of esteemed and popular Bible commentary volumes based on the New International Version text.

Statistics for Spatial Data

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Publisher : John Wiley & Sons
ISBN 13 : 1119115183
Total Pages : 931 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Statistics for Spatial Data by : Noel Cressie

Download or read book Statistics for Spatial Data written by Noel Cressie and published by John Wiley & Sons. This book was released on 2015-03-18 with total page 931 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Wiley Classics Library consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. Spatial statistics — analyzing spatial data through statistical models — has proven exceptionally versatile, encompassing problems ranging from the microscopic to the astronomic. However, for the scientist and engineer faced only with scattered and uneven treatments of the subject in the scientific literature, learning how to make practical use of spatial statistics in day-to-day analytical work is very difficult. Designed exclusively for scientists eager to tap into the enormous potential of this analytical tool and upgrade their range of technical skills, Statistics for Spatial Data is a comprehensive, single-source guide to both the theory and applied aspects of spatial statistical methods. The hard-cover edition was hailed by Mathematical Reviews as an "excellent book which will become a basic reference." This paper-back edition of the 1993 edition, is designed to meet the many technological challenges facing the scientist and engineer. Concentrating on the three areas of geostatistical data, lattice data, and point patterns, the book sheds light on the link between data and model, revealing how design, inference, and diagnostics are an outgrowth of that link. It then explores new methods to reveal just how spatial statistical models can be used to solve important problems in a host of areas in science and engineering. Discussion includes: Exploratory spatial data analysis Spectral theory for stationary processes Spatial scale Simulation methods for spatial processes Spatial bootstrapping Statistical image analysis and remote sensing Computational aspects of model fitting Application of models to disease mapping Designed to accommodate the practical needs of the professional, it features a unified and common notation for its subject as well as many detailed examples woven into the text, numerous illustrations (including graphs that illuminate the theory discussed) and over 1,000 references. Fully balancing theory with applications, Statistics for Spatial Data, Revised Edition is an exceptionally clear guide on making optimal use of one of the ascendant analytical tools of the decade, one that has begun to capture the imagination of professionals in biology, earth science, civil, electrical, and agricultural engineering, geography, epidemiology, and ecology.

Ending Discrimination Against People with Mental and Substance Use Disorders

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Author :
Publisher : National Academies Press
ISBN 13 : 0309439124
Total Pages : 171 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Ending Discrimination Against People with Mental and Substance Use Disorders by : National Academies of Sciences, Engineering, and Medicine

Download or read book Ending Discrimination Against People with Mental and Substance Use Disorders written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-09-03 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Estimates indicate that as many as 1 in 4 Americans will experience a mental health problem or will misuse alcohol or drugs in their lifetimes. These disorders are among the most highly stigmatized health conditions in the United States, and they remain barriers to full participation in society in areas as basic as education, housing, and employment. Improving the lives of people with mental health and substance abuse disorders has been a priority in the United States for more than 50 years. The Community Mental Health Act of 1963 is considered a major turning point in America's efforts to improve behavioral healthcare. It ushered in an era of optimism and hope and laid the groundwork for the consumer movement and new models of recovery. The consumer movement gave voice to people with mental and substance use disorders and brought their perspectives and experience into national discussions about mental health. However over the same 50-year period, positive change in American public attitudes and beliefs about mental and substance use disorders has lagged behind these advances. Stigma is a complex social phenomenon based on a relationship between an attribute and a stereotype that assigns undesirable labels, qualities, and behaviors to a person with that attribute. Labeled individuals are then socially devalued, which leads to inequality and discrimination. This report contributes to national efforts to understand and change attitudes, beliefs and behaviors that can lead to stigma and discrimination. Changing stigma in a lasting way will require coordinated efforts, which are based on the best possible evidence, supported at the national level with multiyear funding, and planned and implemented by an effective coalition of representative stakeholders. Ending Discrimination Against People with Mental and Substance Use Disorders: The Evidence for Stigma Change explores stigma and discrimination faced by individuals with mental or substance use disorders and recommends effective strategies for reducing stigma and encouraging people to seek treatment and other supportive services. It offers a set of conclusions and recommendations about successful stigma change strategies and the research needed to inform and evaluate these efforts in the United States.

Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis

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Author :
Publisher : OUP USA
ISBN 13 : 0195133641
Total Pages : 319 pages
Book Rating : 4.1/5 (951 download)

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Book Synopsis Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis by : Diana B. Petitti

Download or read book Meta-Analysis, Decision Analysis, and Cost-Effectiveness Analysis written by Diana B. Petitti and published by OUP USA. This book was released on 2000 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public health and in health policy courses at the undergraduate and graduate level.

The Big Book of Canada

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Publisher : Tundra Books (NY)
ISBN 13 : 0887764576
Total Pages : 262 pages
Book Rating : 4.8/5 (877 download)

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Book Synopsis The Big Book of Canada by : Christopher Moore

Download or read book The Big Book of Canada written by Christopher Moore and published by Tundra Books (NY). This book was released on 2002 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides information and photographs on Canada, exploring the history, politics, territories, and people that have formed this nation.

Acts

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Publisher : B&H Publishing Group
ISBN 13 : 1433675641
Total Pages : 537 pages
Book Rating : 4.4/5 (336 download)

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Book Synopsis Acts by : John B. Polhill

Download or read book Acts written by John B. Polhill and published by B&H Publishing Group. This book was released on 1992-01-06 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE NEW AMERICAN COMMENTARY is for the minister or Bible student who wants to understand and expound the Scriptures. Notable features include:* commentary based on THE NEW INTERNATIONAL VERSION;* the NIV text printed in the body of the commentary;* sound scholarly methodology that reflects capable research in the original languages;* interpretation that emphasizes the theological unity of each book and of Scripture as a whole;* readable and applicable exposition.

Nebraska Highway 35 (N-35) Corridor, Norfolk, Nebraska to South Sioux City, Nebraska, Madison, Stanton, Wayne, Dixon, and Dakota Counties

Download Nebraska Highway 35 (N-35) Corridor, Norfolk, Nebraska to South Sioux City, Nebraska, Madison, Stanton, Wayne, Dixon, and Dakota Counties PDF Online Free

Author :
Publisher :
ISBN 13 :
Total Pages : 266 pages
Book Rating : 4.3/5 (555 download)

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Book Synopsis Nebraska Highway 35 (N-35) Corridor, Norfolk, Nebraska to South Sioux City, Nebraska, Madison, Stanton, Wayne, Dixon, and Dakota Counties by :

Download or read book Nebraska Highway 35 (N-35) Corridor, Norfolk, Nebraska to South Sioux City, Nebraska, Madison, Stanton, Wayne, Dixon, and Dakota Counties written by and published by . This book was released on 2007 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Monthly Bulletin

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Publisher :
ISBN 13 :
Total Pages : 1410 pages
Book Rating : 4.3/5 (117 download)

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Book Synopsis Monthly Bulletin by :

Download or read book Monthly Bulletin written by and published by . This book was released on 1900 with total page 1410 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Bulletin of the Pan American Union

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Publisher :
ISBN 13 :
Total Pages : 1278 pages
Book Rating : 4.7/5 (869 download)

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Book Synopsis Bulletin of the Pan American Union by : Pan American Union

Download or read book Bulletin of the Pan American Union written by Pan American Union and published by . This book was released on 1900 with total page 1278 pages. Available in PDF, EPUB and Kindle. Book excerpt: